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  • Search results for: 'CASPASE-8'

Search results for: 'CASPASE-8'

Items 41-50 of 147

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  1. VX-745
    A8686 VX-745
    Target: p38
    Summary: P38α inhibitor,highly potent and selective
      ≥21.8 mg/mL
  2. ME0328
    A8808 ME0328
    Target: PARP
    Summary: PARP inhibitor,potent and selective
      ≥71.43 mg/mL
  3. CRT0044876
    B3061 CRT0044876
    Target: AP endonucleases
    Summary: APE1 inhibitor, potent and selective
      ≥55.56 mg/mL
  4. NMS-873
    B2168 NMS-873
     3 Citation
    Target: Valosin-containing protein (VCP)
    Summary: VCP/p97 inhibitor,selective and allosteric
      insoluble in H2O; ≥17.1 mg/mL
  5. Beta-Lapachone
    B2290 Beta-Lapachone
    Target: Topoisomerases
    Summary: DNA topoisomerase I inhibitor,selective
      insoluble in H2O; ≥10.85 mg/mL
  6. Zanamivir
    B2136 Zanamivir
    Target: Influenza viruses
    Summary: Influenza A/B virus neuraminidases inhibitor
      insoluble in DMSO; insoluble in EtOH; ≥8.99 mg/mL
  7. Anidulafungin
    B1224 Anidulafungin
     1 Citation
    Target: Glucan synthase
    Summary: Antifungal drug
      insoluble in EtOH; insoluble in H2O; ≥20.8 mg/mL
  8. Raloxifene HCl
    B1515 Raloxifene HCl
    Target: Estrogen and Related Receptors
    Summary: Estrogen receptor (ER)
      ≥22.35 mg/mL
  9. D609
    A3343 D609
    Target: PC-PLC
    Summary: PC-PLC inhibitor
      ≥12.7 mg/mL
  10. EMD638683
    A3389 EMD638683
     4 Citation
    Target: SGK
    Summary: SGK1 inhibitor
      insoluble in H2O; ≥18.2 mg/mL

Items 41-50 of 147

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  1. Signaling Pathways 136item
  2. Natural Products 3item
  3. Kits 1 item
  4. Probes & Dyes 1 item
  5. Lab Reagents 3item
Reversibility
  1. Reversible 10item
  2. Irreversible 7item
Target
  1. Caspases 12item
  2. Cyclin-Dependent Kinases 4item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 2item
  5. Cathepsins 2item
  6. Histone Deacetylases (HDACs) 5item
  7. Akt 2item
  8. Bcl-2 1 item
  9. PI3K 2item
  10. mTOR 3item
  11. MMP 2item
  12. Myosin II ATPases 1 item
  13. Voltage-gated Potassium (KV) Channels 1 item
  14. FLT3 3item
  15. GSK-3 1 item
  16. Factor Xa 1 item
  17. P-glycoprotein (P-gp) 1 item
  18. PLK 1 item
  19. Chk 3item
  20. Eph Receptors 1 item
  21. VEGFR 7item
  22. PDGFR 5item
  23. c-Kit 2item
  24. RET 2item
  25. IRAK 1 item
  26. Thymidylate Synthase 1 item
  27. p38 1 item
  28. SGK 1 item
  29. Bcr-Abl 2item
  30. MEK 1 item
  31. DOT1L 1 item
  32. FGFR 3item
  33. GABAB Receptors 1 item
  34. Sir2-like Family Deacetylases (Sirtuins) 1 item
  35. Voltage-gated Sodium (NaV) Channels 1 item
  36. Smoothened 2item
  37. Neuraminidases (NA) 1 item
  38. MET 1 item
  39. Glucan synthase 1 item
  40. Src 4item
  41. RARs 2item
  42. Trk Receptors 1 item
  43. NMDA Receptors 1 item
  44. STAT 2item
  45. ATP Citrate Lyases 1 item
  46. Estrogen and Related Receptors 1 item
  47. EGFR 2item
  48. PAK 1 item
  49. JAK 5item
  50. Syk 1 item
  51. DNA-PK 1 item
  52. CCR 1 item
  53. CFTR 1 item
  54. Topoisomerases 1 item
  55. Cytochrome P450 (CYP450) 2item
  56. Influenza viruses 1 item
  57. Epac 1 item
  58. HMG-CoA Reductases 1 item
  59. c-MET 1 item
  60. Calpains 1 item
  61. HER2 1 item
  62. 5-HT2 Receptors 1 item
  63. LRRK2 1 item
  64. Voltage-gated Calcium Channels (CaV) 1 item
  65. Calcium chelator 1 item
  66. PARP 1 item
  67. CB1 Receptors 1 item
  68. Monocarboxylate transporters (MCTs) 1 item
  69. 5-HT1 Receptors 1 item
  70. Valosin-containing protein (VCP) 1 item
  71. Fatty-acid-binding proteins (FABPs) 1 item
  72. Tie-2 1 item
  73. RSK 1 item
  74. p70 S6K 1 item
  75. ATM/ATR 1 item
  76. Acetylcholine 1 item
  77. COX 1 item
  78. Farnesyl Diphosphate Synthases 1 item
  79. G-quadruplexes 1 item
  80. SRPK1 1 item
  81. Carbonic Anhydrases 1 item
  82. AP endonucleases 1 item
  83. Aldehyde Dehydrogenases 1 item
  84. Synthases/Synthetases 1 item
  85. MAGL 1 item
  86. Histamine H1 Receptors 1 item
  87. P110 1 item
  88. Hck 1 item
  89. SETD7 1 item
  90. Norepinephrine transporter 1 item
  91. 5-HT Transporters 3item
  92. Ionophores 1 item
  93. NO Donors / Precursors 1 item
  94. CB2 Receptors 1 item
  95. Norepinephrine transporters 1 item
  96. Inward Rectifier Potassium (Kir) Channels 1 item
  97. ZAP-70 1 item
  98. fibrinolysis 1 item
  99. Na /Ca2 Exchangers (NCXs) 1 item
  100. GPR40 1 item
  101. 15-PGDH 1 item
  102. DPP-4 2item
  103. c-RET 1 item
  104. TAM kinase 1 item
  105. endothelin receptor 1 item
  106. Protein polybromo-1 1 item
  107. SMARCA4 1 item
  108. SMARCA2 1 item
  109. adrenoceptor 1 item
  110. PPAR 1 item
  111. PC-PLC 1 item
  112. P97 ATPase 1 item
  113. Calcium-Sensing Receptors (CaSRs) 1 item
  114. SK 1 item
  115. IDO 1 item
  116. Androgen Receptor 1 item
  117. Insulin Receptor 1 item
Reported Experiments
  1. Animal Experiments 123item
  2. Cell Experiments 89item
Related Disease
  1. Acute Kidney Injury 1 item
  2. Acute Myelogenous Leukemia 1 item
  3. Acute Myeloid Leukemia 2item
  4. Adrenocortical Carcinoma 1 item
  5. Advanced Renal Cell Carcinoma 1 item
  6. Bacteria Infection 1 item
  7. Bladder Cancer 3item
  8. Bladder Diseases 1 item
  9. Brain Injuries Studies 2item
  10. Breast Cancer 13item
  11. Cancer 59item
  12. Chronic Lymphocytic Leukemia 1 item
  13. Chronic Myeloproliferative Disorders 1 item
  14. Clear Cell Renal Cell Carcinoma 1 item
  15. Cocaine Abuse 1 item
  16. Cocaine-Related Disorders 1 item
  17. Colon Cancer 7item
  18. Colorectal Cancer 4item
  19. Depression 1 item
  20. Diabetes 3item
  21. Epilepsy 1 item
  22. Fungal Infection 1 item
  23. Glioblastoma 2item
  24. Glioma 3item
  25. HIV Infections 2item
  26. Hypercholesterolemia 1 item
  27. Inflammatory Diseases 2item
  28. Influenza 2item
  29. Kidney Injury Studies 1 item
  30. Leukemia 6item
  31. Lung Cancer 5item
  32. Lymphoma 5item
  33. Melanoma 3item
  34. Mixed Lineage Leukemia 1 item
  35. Multiple Myeloma 4item
  36. Myelofibrosis 2item
  37. Myeloma 2item
  38. Neuronal Protection 1 item
  39. Non-small Cell Lung Carcinoma 1 item
  40. Ovarian Cancer 6item
  41. Pancreatic Cancer 7item
  42. Prostate Cancer 6item
  43. Pulmonary Fibrosis 1 item
  44. Renal Cancer 1 item
  45. Rheumatoid Arthritis 3item
  46. Sleep Disorders 1 item
  47. Soft Tissue Sarcoma 1 item
  48. Thyroid Cancer 2item
  49. Type 2 Diabetes 2item