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  • Search results for: 'btk inhibitor 1 hydrochloride'

Search results for: 'btk inhibitor 1 hydrochloride'

Items 1-10 of 852

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  1. IRAK-1-4 Inhibitor I
    A3505 IRAK-1-4 Inhibitor I
     3 Citation
    Target: IRAK
    Summary: IRAK-1/4 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥19.75 mg/mL
  2. IRAK inhibitor 1
    A3500 IRAK inhibitor 1
     2 Citation
    Target: IRAK
    Summary: IRAK-4 inhibitor
      insoluble in EtOH; insoluble in H2O; ≥14.4 mg/mL
  3. Torin 1
    A8312 Torin 1
     7 Citation
    Target: mTOR
    Summary: MTOR inhibitor,potent and selective
  4. BMS345541 hydrochloride
    A3248 BMS345541 hydrochloride
    Target: IKK
    Summary: IKK inhibitor,highly selective
      insoluble in EtOH; insoluble in DMSO; ≥60 mg/mL
  5. PRT062607 Hydrochloride
    A3736 PRT062607 Hydrochloride
     1 Citation
    Target: Syk
    Summary: SYK inhibitor,potent and selective
      ≥21.5 mg/mL
  6. KN-92 hydrochloride
    A3530 KN-92 hydrochloride
    Target: Ca2 /calmodulin-dependent protein kinases (CaMKs)
    Summary: Inactive derivative of KN-93,control compound
      ≥24.65 mg/mL
  7. NB-598 hydrochloride
    A3646 NB-598 hydrochloride
    Target: Squalene epoxidases
    Summary: SE inhibitor
      ≥54 mg/mL
      insoluble in H2O
  8. CGI-1746
    A3302 CGI-1746
     1 Citation
    Target: BTK
    Summary: Btk inhibitor
      ≥29 mg/mL
  9. LKB1 (AAK1 dual inhibitor)
    A3556 LKB1 (AAK1 dual inhibitor)
    Target: Pim
    Summary: Pim-1 kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥34.8 mg/mL
  10. 3-Deazaneplanocin A (DZNep) hydrochloride
    A8182 3-Deazaneplanocin A (DZNep) hydrochloride
     1 Citation
    Target: EZH2
    Summary: SAHH and EZH2 inhibitor
      insoluble in EtOH; ≥14.94 mg/mL

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Category
  1. Proteases 79item
  2. Apoptosis 45item
  3. Chromatin/Epigenetics 107item
  4. Metabolism 63item
  5. MAPK Signaling 46item
  6. Tyrosine Kinase 114item
  7. DNA Damage/DNA Repair 62item
  8. PI3K/Akt/mTOR Signaling 62item
  9. Microbiology & Virology 32item
  10. Cell Cycle/Checkpoint 76item
  11. Ubiquitination/ Proteasome 33item
  12. JAK/STAT Signaling 33item
  13. TGF-β / Smad Signaling 34item
  14. Angiogenesis 9item
  15. GPCR/G protein 39item
  16. Stem Cell 31item
  17. Membrane Transporter/Ion Channel 33item
  18. Endocrinology and Hormones 13item
  19. Neuroscience 31item
  20. Obesity, Appetite Control & Diabetes 1 item
  21. Other Signal Transduction 2item
  22. Others 69item
  23. Immunology/Inflammation 15item
  24. Cardiovascular 1 item
Reversibility
  1. Reversible 54item
  2. Irreversible 25item
Target
  1. Caspases 11item
  2. Cyclin-Dependent Kinases 26item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 11item
  5. Cathepsins 11item
  6. Histone Deacetylases (HDACs) 27item
  7. Inhibitor of apoptosis proteins (IAP) 3item
  8. Akt 6item
  9. Bcl-2 6item
  10. PI3K 27item
  11. CXCR 4item
  12. Raf 10item
  13. Aurora Kinases 14item
  14. Bcl-xl 3item
  15. CSF-1R 2item
  16. Glycoproteins 1 item
  17. p97 1 item
  18. Gap Junctions 1 item
  19. MDM2 1 item
  20. EZH2 6item
  21. mTOR 15item
  22. Bromodomains 5item
  23. AP-1 3item
  24. MMP 10item
  25. Thymidine Phosphorylases 1 item
  26. Androgen Receptors 4item
  27. Peptidylprolyl isomerases 1 item
  28. Acyl coenzyme A: cholesterol acyltransferases 1 item
  29. Myosin II ATPases 1 item
  30. DT-diaphorases 1 item
  31. MER 1 item
  32. FLT3 12item
  33. GSK-3 9item
  34. Factor Xa 3item
  35. LPA Receptors 1 item
  36. P-glycoprotein (P-gp) 5item
  37. PLK 7item
  38. Chk 8item
  39. ULK1 1 item
  40. Eph Receptors 3item
  41. VEGFR 25item
  42. PDGFR 19item
  43. c-Kit 7item
  44. RET 3item
  45. IRAK 3item
  46. Bromodomain-containing proteins(BRDs) 1 item
  47. Phosphodiesterases (PDEs) 10item
  48. Mcl-1 5item
  49. Hydrolase 1 item
  50. Thymidylate Synthase 2item
  51. p38 9item
  52. PKB 1 item
  53. 3-phosphoglycerate dehydrogenase 1 item
  54. JNK 6item
  55. SGK 2item
  56. Bcr-Abl 10item
  57. Kynurenine-3-monooxygenase 1 item
  58. MEK 15item
  59. PORCN 1 item
  60. DOT1L 3item
  61. FGFR 9item
  62. Nrf2 1 item
  63. Insulin-like growth factor receptors(IGFRs) 1 item
  64. CGRP receptors 1 item
  65. Pim 4item
  66. GABAB Receptors 1 item
  67. Glucagon-like peptide 1 (GLP-1) receptors 2item
  68. Sir2-like Family Deacetylases (Sirtuins) 3item
  69. Deubiquitinating enzymes (DUBs) 4item
  70. PP1 1 item
  71. PP2A 1 item
  72. Smoothened 4item
  73. Eukaryotic elongation factors 1 item
  74. Ribosomal s6 kinases (RSK) 1 item
  75. Neuraminidases (NA) 1 item
  76. MET 7item
  77. Src 9item
  78. Trk Receptors 5item
  79. Integrins 1 item
  80. Aminopeptidases 2item
  81. STAT 5item
  82. ATP Citrate Lyases 1 item
  83. Microtubules/Tubulins 5item
  84. EGFR 15item
  85. Hedgehog 1 item
  86. Reverse Transcriptases 1 item
  87. ROCK 7item
  88. BTK 2item
  89. RIP kinases 1 item
  90. PAK 3item
  91. Hypoxia Inducible Factors (HIFs) 2item
  92. Tankyrases 1 item
  93. Inositol Phosphatases 1 item
  94. FAK 5item
  95. BMP and Other Activin Receptors 4item
  96. JAK 13item
  97. p300 1 item
  98. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  99. Syk 7item
  100. Progesterone Receptors 1 item
  101. EZH1 2item
  102. DNA-PK 6item
  103. HSP90 10item
  104. AMPK 3item
  105. Gutathione S-transferase 1 item
  106. CCR 2item
  107. PDHK 1 item
  108. Angiotensin AT2 Receptors 1 item
  109. eIF4E/eIF3G interaction 1 item
  110. Notch 1 item
  111. S-nitrosoglutathione reductase 1 item
  112. CFTR 2item
  113. TNKS 1 item
  114. Topoisomerases 7item
  115. Cytochrome P450 (CYP450) 6item
  116. thrombin 1 item
  117. Ksp 1 item
  118. Ribosomes 1 item
  119. Renin 2item
  120. HIV proteases 1 item
  121. Pepsins 1 item
  122. Influenza viruses 1 item
  123. ErbB 2item
  124. Ferroptosis 1 item
  125. S6 kinases 1 item
  126. Toll-like receptors (TLRs) 2item
  127. Adenosine Kinases 2item
  128. Actin 1 item
  129. DNA Methyltransferases 4item
  130. Survivin 1 item
  131. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  132. ERK 5item
  133. HMG-CoA Reductases 5item
  134. Vacuolar-type ATPase 1 item
  135. c-MET 8item
  136. BMI-1 1 item
  137. PKC 7item
  138. Calpains 5item
  139. Ubiquitin-specific proteases 1 item
  140. HCV Proteases 3item
  141. Ca2 /calmodulin-dependent protein kinases (CaMKs) 8item
  142. MLK3 1 item
  143. SMYD2 1 item
  144. CREBBP 2item
  145. EP300 2item
  146. Protease-Activated Receptors 1 item
  147. Lyn 1 item
  148. SGLT 1 item
  149. RAD51 1 item
  150. Trypsins 1 item
  151. HER2 2item
  152. Pyk2 3item
  153. USP 2item
  154. 5-HT2 Receptors 7item
  155. LRRK2 4item
  156. S1P receptors 1 item
  157. Calcium chelator 1 item
  158. DGAT 2item
  159. Insulin and Insulin-like Receptors 3item
  160. PARP 4item
  161. CB1 Receptors 1 item
  162. Pyruvate dehydrogenases (PDH) 1 item
  163. ALK 5item
  164. ROS1 2item
  165. Sphingosine kinases (SphKs) 2item
  166. Trypsin 1 item
  167. Chymotrypsin 1 item
  168. Kallikrein 1 item
  169. Trypsinogen 1 item
  170. KRAS G12C 1 item
  171. GTPases 1 item
  172. Monocarboxylate transporters (MCTs) 1 item
  173. CETP 2item
  174. Dehydrogenase 1 item
  175. PKG 1 item
  176. PKA 1 item
  177. Myosin light chain kinases (MLCKs) 2item
  178. GPR30 1 item
  179. HIV-1 gp120 1 item
  180. D1 and D5 Receptors 1 item
  181. D2 Receptors 4item
  182. D3 Receptors 2item
  183. 5-HT1 Receptors 2item
  184. 5-HT7 Receptors 1 item
  185. CaM-KK 1 item
  186. Valosin-containing protein (VCP) 1 item
  187. MELK 1 item
  188. Serotonin reuptake 1 item
  189. Insulin-like growth factors (IGFs) 1 item
  190. Clk 1 item
  191. TBK1 1 item
  192. MARK1 1 item
  193. NUAK1 2item
  194. Integrin-ligand interactions 1 item
  195. CSF1R 1 item
  196. Bromodomain and Extra-Terminal motif (BET) 1 item
  197. NUAK2 1 item
  198. Na /H Exchangers (NHEs) 1 item
  199. Lactate Dehydrogenases (LDH) 2item
  200. MK2 3item
  201. Fatty-acid-binding proteins (FABPs) 1 item
  202. 5-HT3 Receptors 1 item
  203. Angiotensin-Converting Enzymes (ACEs) 2item
  204. Tie-2 4item
  205. RSK 2item
  206. p70 S6K 1 item
  207. Free Fatty Acid Receptors 1 item
  208. phosphatases 1 item
  209. Autophagy 2item
  210. ATM/ATR 7item
  211. Mixed lineage kinase domain-like protein (MLKL) 1 item
  212. COX 6item
  213. Heparanases 1 item
  214. YAP 1 item
  215. CK1 1 item
  216. IDH2 1 item
  217. CK2 3item
  218. HIPK2 1 item
  219. HIPK3 1 item
  220. HIV Integrases 1 item
  221. Cryptochromes 1 item
  222. G-quadruplexes 1 item
  223. Squalene epoxidases 2item
  224. PRAK 1 item
  225. MAPKAP-K2 1 item
  226. Delayed rectifier outward potassium current (IKr) 1 item
  227. 20S proteasomal chymotrypsin 1 item
  228. Geranylgeranyltransferase I 1 item
  229. Farnesyltransferase 1 item
  230. NAT10 1 item
  231. Nampt 2item
  232. eIF4F 1 item
  233. Cdc42 1 item
  234. SRPK1 1 item
  235. P2X Receptors 2item
  236. Glutaminases 1 item
  237. Carbonic Anhydrases 5item
  238. Ron 1 item
  239. AP endonucleases 1 item
  240. G9a 2item
  241. BLM 1 item
  242. HSV 2item
  243. NADPH Oxidases 2item
  244. Glutamate (Metabotropic) Group I Receptors 1 item
  245. Calcium-activated chloride channels (CaCC) 1 item
  246. GPR35 1 item
  247. Aldehyde Dehydrogenases 2item
  248. Synthases/Synthetases 3item
  249. MAGL 1 item
  250. c-Fyn 1 item
  251. Leukotriene and Related Receptors 1 item
  252. TAK1 1 item
  253. Histamine H1 Receptors 2item
  254. Na /K ATPases 2item
  255. P110 1 item
  256. Hck 1 item
  257. Inositol-requiring enzyme 1 (IRE1) 1 item
  258. SETD7 1 item
  259. Na /K /Cl- Symporters (NKCCs) 1 item
  260. GABAA Receptors 1 item
  261. Phospholipases 1 item
  262. TRP Channel 2item
  263. RNA Polymerases 2item
  264. Norepinephrine transporter 1 item
  265. 5-HT Transporters 3item
  266. Xanthine oxidoreductases 1 item
  267. Dihydroorotate dehydrogenase 1 item
  268. Guanylyl Cyclases 1 item
  269. Histone Demethylases 1 item
  270. Apoptosis Inducers 1 item
  271. MNK 1 item
  272. NO Donors / Precursors 1 item
  273. CB2 Receptors 1 item
  274. HIV-1 reverse transcriptase 1 item
  275. IL Receptors 2item
  276. CCL2 1 item
  277. Norepinephrine transporters 1 item
  278. 15-lipoxygenases 1 item
  279. Calcium-Activated Potassium (KCa) Channels 1 item
  280. AChE 2item
  281. Insulin Receptors 1 item
  282. IRG-1R 1 item
  283. Proton Pump 1 item
  284. cAMP 1 item
  285. Sulfonylurea receptors 1 item
  286. eEF-2 1 item
  287. Inward Rectifier Potassium (Kir) Channels 3item
  288. Arp2/3 complex 1 item
  289. CRTH2 1 item
  290. Cdc7 1 item
  291. Nuclear Receptors 1 item
  292. CMV 1 item
  293. ZAP-70 1 item
  294. Catechol O-Methyltransferase (COMT) 2item
  295. fibrinolysis 1 item
  296. Angiotensin AT1 Receptors 2item
  297. D4 Receptors 1 item
  298. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  299. HBV Proteases 1 item
  300. Flk-1 1 item
  301. Papains 1 item
  302. Protein Arginine Methyltransferases 1 item
  303. IMPDH 1 item
  304. Na /Ca2 Exchangers (NCXs) 1 item
  305. NAE 2item
  306. Ubiquitin-activating Enzyme E1 1 item
  307. SUMOylation 1 item
  308. ATGL 1 item
  309. BACE 1 item
  310. Cytidine deaminases 1 item
  311. angiogenesis 1 item
  312. Glucagon Receptors 1 item
  313. 15-PGDH 1 item
  314. DPP-4 4item
  315. PP4 1 item
  316. c-RET 1 item
  317. Nonstructural protein 5B (NS5B) 1 item
  318. ETA Receptors 2item
  319. ETB Receptors 1 item
  320. p70 rsk 1 item
  321. FPTase 1 item
  322. ADAMs 1 item
  323. TAM kinase 1 item
  324. p53-MDM2 interaction 1 item
  325. nuclear export 1 item
  326. CRM1 1 item
  327. AXL 1 item
  328. Protein polybromo-1 1 item
  329. SMARCA4 1 item
  330. SMARCA2 1 item
  331. Dipeptidyl-peptidase II 1 item
  332. HDAC 1 item
  333. c-Fms tyrosine kinase 1 item
  334. human lyase 1 item
  335. Ub-conjugating enzyme (E2) complex 1 item
  336. STK 1 item
  337. IKK 1 item
  338. MSK 1 item
  339. HCV polymerase 2item
  340. Ftase 1 item
  341. PC-PLC 1 item
  342. Elastases 1 item
  343. P97 ATPase 1 item
  344. NTPDases 1 item
  345. Calcium-Sensing Receptors (CaSRs) 1 item
  346. telomerase 1 item
  347. Histone Acetyltransferases (HATs) 1 item
  348. F1 Fo-ATPase 1 item
  349. ITK 1 item
  350. NOD1 1 item
  351. NUAK 1 item
  352. DCLK2 1 item
  353. FAAH 1 item
  354. TYK2 1 item
  355. Lck 1 item
  356. Aromatases 1 item
  357. PKD 1 item
  358. SHIP 1 item
  359. MCL1 1 item
  360. Bcl-w 1 item
  361. tropomyosin receptor kinase 1 item
  362. LSD 1 item
  363. PRMT 1 item
  364. GLP 1 item
  365. SK 1 item
  366. MST 1 item
  367. IDO 1 item
  368. Serotonin (5-HT) reuptake 1 item
  369. Androgen Receptor 1 item
  370. Substance P/NK1 Receptor 1 item
  371. gp120/CD4 1 item
  372. ATM 2item
  373. Sirtuin 1 item
  374. NE 1 item
  375. CRF1 Receptors 1 item
  376. PIKfyve 1 item
  377. Glycogen Phosphorylases 1 item
  378. MTH1 1 item
  379. Insulin Receptor 1 item
Reported Experiments
  1. Animal Experiments 728item
  2. Cell Experiments 501item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acne 1 item
  3. Acute Disseminated Candidiasis 1 item
  4. Acute Kidney Injury 1 item
  5. Acute Lung Injury 1 item
  6. Acute Myelogenous Leukemia 6item
  7. Acute Myeloid Leukemia 27item
  8. Acute Renal Failure 1 item
  9. Adrenocortical Carcinoma 4item
  10. Advanced Renal Cell Carcinoma 1 item
  11. Autoimmune Diseases 1 item
  12. Bacterial Infectios 1 item
  13. Biliary Cancer 1 item
  14. Bladder Cancer 10item
  15. Bladder Carcinoma 4item
  16. Bladder Diseases 2item
  17. B-lymphoid Malignancies 1 item
  18. Brain Injuries Studies 3item
  19. Breast Cancer 119item
  20. Cancer 449item
  21. Candida Peritonitis 1 item
  22. Candidemia 1 item
  23. Castration-resistant Prostate Cancer 1 item
  24. Cervical Cancer 5item
  25. Cholangiocarcinoma 2item
  26. Chronic Lymphocytic Leukemia 8item
  27. Chronic Myeloproliferative Disorders 1 item
  28. Clear Cell Renal Cell Carcinoma 2item
  29. Cocaine-Related Disorders 2item
  30. Colon Cancer 46item
  31. Colon Carcinoma 7item
  32. Colorectal Cancer 42item
  33. Depression 2item
  34. Diabetes 8item
  35. Diffuse Large B-cell Lymphoma 1 item
  36. Dyskinesia 1 item
  37. Dyslipidemia 2item
  38. Epilepsy 2item
  39. Erectile Dysfunction 3item
  40. Friedreich's Ataxia 1 item
  41. Fungal Infection 1 item
  42. Glioblastoma 35item
  43. Glioma 19item
  44. HCV 3item
  45. Heart Failure 1 item
  46. Hepatic Cancer 2item
  47. Hepatitis C 3item
  48. Hepatocellular Carcinoma 8item
  49. HIV 5item
  50. HIV Infections 11item
  51. Hypercholesterolemia 2item
  52. Immunological Diseases 1 item
  53. Inflammation 1 item
  54. Inflammatory Bowel Disease 1 item
  55. Inflammatory Diseases 16item
  56. Influenza 2item
  57. Kidney Injury Studies 1 item
  58. Leukemia 23item
  59. Liver Cancer 3item
  60. Lung Cancer 45item
  61. Lung Carcinoma 4item
  62. Lymphoma 31item
  63. Mantle Cell Lymphoma 2item
  64. Medulloblastoma 1 item
  65. Melanoma 38item
  66. Mixed Lineage Leukemia 3item
  67. Multidrug Resistance Studies 1 item
  68. Multiple Myeloma 24item
  69. Myelofibrosis 2item
  70. Myeloma 7item
  71. Narcolepsy 1 item
  72. Neuroblastoma 14item
  73. Neurocognitive Disorders 1 item
  74. Neuronal Protection 1 item
  75. Non-small Cell Lung Cancer 26item
  76. Non-small Cell Lung Carcinoma 2item
  77. Obsessive-Compulsive Disorder 1 item
  78. Osteoporosis 2item
  79. Ovarian Cancer 35item
  80. Pancreatic Cancer 48item
  81. Pancreatic Carcinoma 3item
  82. Prostate Cancer 57item
  83. Psoriasis 4item
  84. Psoriasis Vulgaris 1 item
  85. Pulmonary Arterial Hypertension 2item
  86. Pulmonary Fibrosis 2item
  87. Renal Cancer 4item
  88. Renal Cell Carcinoma 8item
  89. Rheumatoid Arthritis 14item
  90. Sarcoma 1 item
  91. Schizophrenia 8item
  92. Sleep Disorders 1 item
  93. Soft Tissue Sarcoma 1 item
  94. Squamous Cell Carcinoma 2item
  95. Testicular Cancer 2item
  96. Thyroid Cancer 6item
  97. Tuberculosis 1 item
  98. Type 2 Diabetes 18item