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Search results for: 'btk inhibitor 1 hydrochloride'

Items 421-430 of 882

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  1. Tacrolimus (FK506)
    B2143 Tacrolimus (FK506)
     2 Citation
    Target: Peptidylprolyl isomerases
    Summary: Macrolide calcineurin inhibitor,immunosuppressant
      ≥26.6 mg/mL
  2. Lomeguatrib
    A1912 Lomeguatrib
    Target: O6-methylguanine-DNA-methyl-transferase (MGMT)
    Summary: MGMT inhibitor
      ≥50 mg/mL
  3. RG2833
    A3761 RG2833
    Target: HDAC
    Summary: Brain-penetrant HDAC inhibitor
      insoluble in H2O; ≥16.95 mg/mL
  4. AZD3839
    B3224 AZD3839
    Target: BACE
    Summary: BACE1 inhibitor,potent and selective
      Soluble in DMSO
  5. Salinosporamide A (NPI-0052, Marizomib)
    A4010 Salinosporamide A (NPI-0052, Marizomib)
    Target: Proteasome
    Summary: 20S proteasome inhibitor
      Soluble in DMSO
  6. Triapine
    B3209 Triapine
    Target: Ribonucleotide Reductases
    Summary: Ribonucleotide reductase inhibitor
      ≥83.33 mg/mL
  7. GDC-0032
    B1047 GDC-0032
    Target: PI3K
    Summary: PI3Kα inhibitor
      ≥23.05 mg/mL
  8. Curcumin
    A3335 Curcumin
     1 Citation
    Target: Histone Deacetylases (HDACs)|Nrf2|Histone Acetyltransferases (HATs)|Tyrosinases
    Summary: Tyrosinase inhibitor
      ≥36.8 mg/mL
  9. LY2801653
    A3573 LY2801653
    Target: MET
    Summary: MET inhibitor
      ≥27.65 mg/mL
  10. GKT137831
    B4763 GKT137831
     1 Citation
    Target: NADPH Oxidases
    Summary: dual NADPH oxidase Nox1/Nox4 inhibitor
      ≥39.5 mg/mL

Items 421-430 of 882

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  1. Signaling Pathways 834item
  2. Natural Products 12item
  3. Protein 2item
  4. Peptides 1 item
  5. Probes & Dyes 1 item
  6. Peptides & Proteins 4item
  7. Lab Reagents 12item
Specificity
  1. Selective 522item
  2. Non-Selective 4item
Reversibility
  1. Reversible 34item
  2. Irreversible 25item
Target
  1. Caspases 7item
  2. Cyclin-Dependent Kinases 21item
  3. Proteasome 11item
  4. Cathepsins 5item
  5. Histone Deacetylases (HDACs) 27item
  6. Inhibitor of apoptosis proteins (IAP) 1 item
  7. Akt 11item
  8. Bcl-2 8item
  9. PI3K 28item
  10. CXCR 2item
  11. Raf 10item
  12. Aurora Kinases 18item
  13. Bcl-xl 3item
  14. CSF-1R 4item
  15. Glycoproteins 1 item
  16. p97 1 item
  17. Gap Junctions 1 item
  18. MDM2 2item
  19. EZH2 3item
  20. mTOR 16item
  21. Bromodomains 5item
  22. AP-1 3item
  23. MMP 7item
  24. Thymidine Phosphorylases 1 item
  25. Androgen Receptors 3item
  26. Peptidylprolyl isomerases 1 item
  27. Acyl coenzyme A: cholesterol acyltransferases 1 item
  28. Myosin II ATPases 1 item
  29. DT-diaphorases 1 item
  30. Voltage-gated Potassium (KV) Channels 1 item
  31. MER 1 item
  32. FLT3 16item
  33. GSK-3 6item
  34. Factor Xa 4item
  35. LPA Receptors 2item
  36. P-glycoprotein (P-gp) 3item
  37. PLK 9item
  38. Chk 4item
  39. Eph Receptors 2item
  40. VEGFR 28item
  41. PDGFR 19item
  42. c-Kit 9item
  43. RET 2item
  44. IRAK 2item
  45. Bromodomain-containing proteins(BRDs) 1 item
  46. Phosphodiesterases (PDEs) 12item
  47. Mcl-1 5item
  48. Hydrolase 1 item
  49. Thymidylate Synthase 3item
  50. p38 7item
  51. PKB 1 item
  52. JNK 2item
  53. Bcr-Abl 10item
  54. MEK 8item
  55. PORCN 1 item
  56. DOT1L 1 item
  57. FGFR 10item
  58. Nrf2 1 item
  59. Pim 4item
  60. Liver X receptors (LXRs) 1 item
  61. Sir2-like Family Deacetylases (Sirtuins) 2item
  62. Voltage-gated Sodium (NaV) Channels 1 item
  63. Deubiquitinating enzymes (DUBs) 2item
  64. PP1 1 item
  65. PP2A 1 item
  66. Smoothened 1 item
  67. Neuraminidases (NA) 1 item
  68. MET 5item
  69. Src 14item
  70. Trk Receptors 4item
  71. Aminopeptidases 2item
  72. NMDA Receptors 2item
  73. STAT 8item
  74. Microtubules/Tubulins 1 item
  75. Estrogen and Related Receptors 2item
  76. EGFR 19item
  77. Reverse Transcriptases 6item
  78. ROCK 7item
  79. Hypoxia Inducible Factors (HIFs) 1 item
  80. FAK 4item
  81. JAK 17item
  82. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  83. Syk 4item
  84. Progesterone Receptors 1 item
  85. EZH1 1 item
  86. DNA-PK 6item
  87. HSP90 8item
  88. AMPK 2item
  89. CCR 1 item
  90. Angiotensin AT2 Receptors 1 item
  91. CFTR 2item
  92. Topoisomerases 15item
  93. Cytochrome P450 (CYP450) 8item
  94. Ksp 1 item
  95. Renin 1 item
  96. ErbB 4item
  97. Toll-like receptors (TLRs) 3item
  98. Actin 2item
  99. Serine Proteases 1 item
  100. DNA Methyltransferases 3item
  101. ERK 7item
  102. HMG-CoA Reductases 4item
  103. c-MET 6item
  104. PKC 11item
  105. Calpains 3item
  106. Ca2 /calmodulin-dependent protein kinases (CaMKs) 5item
  107. Protease-Activated Receptors 1 item
  108. Lyn 1 item
  109. RAD51 1 item
  110. HER2 1 item
  111. Pyk2 2item
  112. USP 1 item
  113. 5-HT2 Receptors 5item
  114. LRRK2 5item
  115. S1P receptors 1 item
  116. Voltage-gated Calcium Channels (CaV) 2item
  117. DGAT 1 item
  118. Insulin and Insulin-like Receptors 4item
  119. PARP 7item
  120. CB1 Receptors 2item
  121. Pyruvate dehydrogenases (PDH) 1 item
  122. ALK 7item
  123. Sphingosine kinases (SphKs) 2item
  124. Monocarboxylate transporters (MCTs) 1 item
  125. CETP 1 item
  126. PKG 2item
  127. PKA 5item
  128. Myosin light chain kinases (MLCKs) 2item
  129. GPR30 1 item
  130. D1 and D5 Receptors 1 item
  131. D2 Receptors 3item
  132. D3 Receptors 2item
  133. 5-HT1 Receptors 2item
  134. 5-HT7 Receptors 1 item
  135. Lactate Dehydrogenases (LDH) 2item
  136. MK2 2item
  137. 5-HT3 Receptors 2item
  138. Angiotensin-Converting Enzymes (ACEs) 5item
  139. Tie-2 3item
  140. RSK 2item
  141. phosphatases 2item
  142. Autophagy 3item
  143. ATM/ATR 5item
  144. COX 11item
  145. YAP 1 item
  146. CK1 1 item
  147. CK2 4item
  148. HIPK2 1 item
  149. HIPK3 1 item
  150. HIV Integrases 2item
  151. Pregnane X Receptors 1 item
  152. Squalene epoxidases 2item
  153. PRAK 1 item
  154. MAPKAP-K2 1 item
  155. GpIIb/IIIa receptor 1 item
  156. Guanine nucleotide exchange factors (GEFs) 1 item
  157. 20S proteasomal chymotrypsin 1 item
  158. Geranylgeranyltransferase I 1 item
  159. Farnesyltransferase 1 item
  160. Nampt 3item
  161. eIF4F 1 item
  162. Cdc42 1 item
  163. SRPK1 1 item
  164. P2X Receptors 2item
  165. Glutaminases 2item
  166. Carbonic Anhydrases 7item
  167. Ron 1 item
  168. G9a 1 item
  169. BLM 1 item
  170. HSV 2item
  171. NADPH Oxidases 3item
  172. Glutamate (Metabotropic) Group I Receptors 1 item
  173. Calcium-activated chloride channels (CaCC) 1 item
  174. GPR35 1 item
  175. Aldehyde Dehydrogenases 2item
  176. Synthases/Synthetases 2item
  177. MAGL 2item
  178. Leukotriene and Related Receptors 1 item
  179. Histamine H1 Receptors 5item
  180. RAR/RXR 1 item
  181. Sigma Receptors 1 item
  182. Na /K ATPases 3item
  183. P110 1 item
  184. Hck 2item
  185. Inositol-requiring enzyme 1 (IRE1) 3item
  186. Na /K /Cl- Symporters (NKCCs) 2item
  187. GABAA Receptors 1 item
  188. Phospholipases 1 item
  189. Monoamine oxidases (MAOs) 1 item
  190. Organic anion transporters (OATs) 1 item
  191. TRP Channel 3item
  192. RNA Polymerases 3item
  193. DYRK 1 item
  194. Norepinephrine transporter 1 item
  195. 5-HT Transporters 3item
  196. Xanthine oxidoreductases 1 item
  197. Dihydroorotate dehydrogenase 1 item
  198. Guanylyl Cyclases 1 item
  199. Histone Demethylases 2item
  200. MNK 2item
  201. 5-Lipoxygenases 1 item
  202. NO Donors / Precursors 2item
  203. CB2 Receptors 2item
  204. HIV-1 reverse transcriptase 1 item
  205. IL Receptors 2item
  206. CCL2 1 item
  207. Noradrenaline reuptake 1 item
  208. Norepinephrine transporters 1 item
  209. 15-lipoxygenases 1 item
  210. Calcium-Activated Potassium (KCa) Channels 2item
  211. AChE 3item
  212. Insulin Receptors 1 item
  213. IRG-1R 1 item
  214. cAMP 1 item
  215. Sulfonylurea receptors 1 item
  216. Cdc2-like kinase (Clk) 1 item
  217. eEF-2 1 item
  218. Inward Rectifier Potassium (Kir) Channels 3item
  219. CRTH2 1 item
  220. Cdc7 1 item
  221. Nuclear Receptors 1 item
  222. CMV 1 item
  223. ZAP-70 1 item
  224. Catechol O-Methyltransferase (COMT) 2item
  225. fibrinolysis 1 item
  226. Angiotensin AT1 Receptors 3item
  227. D4 Receptors 1 item
  228. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  229. NMDA receptor 1 item
  230. HBV Proteases 1 item
  231. Hydroxylases 2item
  232. Flk-1 1 item
  233. Papains 1 item
  234. Protein Arginine Methyltransferases 1 item
  235. IMPDH 1 item
  236. Na /Ca2 Exchangers (NCXs) 1 item
  237. NAE 2item
  238. Ubiquitin-activating Enzyme E1 2item
  239. SUMOylation 1 item
  240. ATGL 1 item
  241. BACE 2item
  242. Cytidine deaminases 1 item
  243. angiogenesis 1 item
  244. Glucagon Receptors 1 item
  245. 15-PGDH 1 item
  246. DPP-4 5item
  247. PP4 1 item
  248. c-RET 3item
  249. Nonstructural protein 5B (NS5B) 1 item
  250. guanylyl cyclase 2item
  251. ETA Receptors 2item
  252. ETB Receptors 1 item
  253. p70 rsk 3item
  254. voltage-gated chloride channels 1 item
  255. FPTase 1 item
  256. dopamine receptor 1 item
  257. 5-HT1 Receptor 2item
  258. 5-HT2 Receptor 1 item
  259. Microtubule/Tubulin 1 item
  260. VEGFR3/FLT4 1 item
  261. NTRK1/TRKA 1 item
  262. CSF-1R/c-Fms 1 item
  263. Menin-MLL 2item
  264. Tryptophan hydroxylases (TPH) 2item
  265. ADAMs 1 item
  266. NMPRTase 1 item
  267. Bfl-1 1 item
  268. TAM kinase 1 item
  269. p53-MDM2 interaction 2item
  270. nuclear export 1 item
  271. CRM1 1 item
  272. PTP 1 item
  273. KDR 2item
  274. Fyn kinase 1 item
  275. Abl kinases 1 item
  276. Trypsin-like protease 1 item
  277. AXL 1 item
  278. Glyoxalase I 1 item
  279. dCTP Pyrophosphatases 1 item
  280. Protein polybromo-1 1 item
  281. SMARCA4 1 item
  282. SMARCA2 1 item
  283. ERAD 1 item
  284. Dipeptidyl-peptidase II 1 item
  285. p53 5item
  286. metalloprotease 1 item
  287. HDAC 2item
  288. Antifungal 1 item
  289. KDM 2item
  290. 5-HT receptors 1 item
  291. sodium channel 3item
  292. c-Fms tyrosine kinase 1 item
  293. PAR 1 item
  294. human lyase 1 item
  295. insulin 1 item
  296. Ub-conjugating enzyme (E2) complex 1 item
  297. Smoothened receptor 1 item
  298. quinone oxidoreductase 1 item
  299. cysteine protease 2item
  300. PPAR 1 item
  301. STK 1 item
  302. USP1/USF1 complex 1 item
  303. IKK 1 item
  304. MSK 1 item
  305. gp120-CD4 interaction 1 item
  306. TRPV 1 item
  307. HCV polymerase 3item
  308. Ftase 1 item
  309. Subtilisin/Kex2p-like proprotein convertase 1 item
  310. PC-PLC 2item
  311. Elastases 1 item
  312. P97 ATPase 1 item
  313. ATP synthase 1 item
  314. Glucosidases 1 item
  315. NTPDases 1 item
  316. Vitamin D receptors (VDRs) 1 item
  317. Antibiotic 4item
  318. Mer tyrosine kinase 1 item
  319. Hec1 1 item
  320. Calmodulins 1 item
  321. neprilysin 1 item
  322. Calcium-Sensing Receptors (CaSRs) 2item
  323. GLI 1 item
  324. decarboxylase 1 item
  325. Stem Cell Differentiation 1 item
  326. PP2A/Nkd interaction 1 item
  327. HMGCR 1 item
  328. AAT 1 item
  329. ErbB-2 1 item
  330. adrenergic receptor 2item
  331. HIV 1 item
  332. 5-HT4 Receptor 1 item
  333. PAR receptor 1 item
  334. TRPA 1 item
  335. sterol demethylase 1 item
  336. PDK-1 1 item
  337. GAPDH 1 item
  338. telomerase 1 item
  339. Histone Acetyltransferases (HATs) 3item
  340. complex I of the mitochondrial electron transport chain 1 item
  341. F1 Fo-ATPase 1 item
  342. Prk 1 item
  343. potassium channel 1 item
  344. calcium channel 1 item
  345. Ribonucleotide Reductases 1 item
  346. Trx 1 item
  347. Tyrosinases 1 item
  348. Neurokinin receptor 1 item
  349. HSP70 1 item
  350. ICAM 1 item
  351. ITK 1 item
  352. HIF-PH 1 item
  353. NOD1 1 item
  354. troponin 1 item
  355. NUAK 1 item
  356. Rho 1 item
  357. Aryl hydrocarbon receptors (AHRs) 1 item
  358. Ubiquitin E3 Ligases 1 item
  359. DCLK2 1 item
  360. FAAH 1 item
  361. PTK 1 item
  362. integrase 1 item
  363. L3MBTL 1 item
  364. NOS 2item
  365. MDMX 1 item
  366. TYK2 2item
  367. MUSK 1 item
  368. MAP3K 1 item
  369. GPR3 1 item
  370. Lck 1 item
  371. Adenosine Deaminases 2item
  372. mitochondrial pyruvate carrier (MPC) 1 item
  373. DNA gyrase 1 item
  374. prolactin secretion 1 item
  375. gonadotropin release 1 item
  376. DprE 1 item
  377. Vitamin D 1 item
  378. carnitine reabsorption 1 item
  379. Histamine receptors 1 item
  380. GluR 1 item
  381. 5-HT receptor 1 item
  382. dopamine receptors 1 item
  383. AMPA receptor 1 item
  384. 5-alpha Reductases 1 item
  385. Flk1 2item
  386. SAPK 1 item
  387. p21 1 item
  388. DNA Ligases 1 item
  389. Prostaglandin synthesis 1 item
  390. Protein Tyrosine Phosphatases 1 item
  391. alkaline phosphatases 1 item
  392. ATPases 1 item
  393. glutamate release 1 item
  394. PAFR 1 item
  395. Aromatases 2item
  396. DHFR 1 item
  397. GARFT 1 item
  398. 5-HT 1 item
  399. PHF 1 item
  400. FGR 1 item
  401. YES 2item
  402. Fyn 2item
  403. ARG 1 item
  404. Autotaxin 1 item
  405. UCH 1 item
  406. RHA 1 item
  407. HCV NS3-4A protease 1 item
  408. TRPC channel 1 item
  409. PKD 1 item
  410. Octamer-binding transcription factor 4 (Oct4) 1 item
  411. Pyruvate kinases 1 item
  412. Thioredoxin Reductases 1 item
  413. enoyl-acyl-carrier protein reductase 1 item
  414. SHIP 1 item
  415. MCL1 1 item
  416. Bcl-w 1 item
  417. glutathione peroxidase 4 1 item
  418. NADH oxidase 1 item
  419. S-adenosylhomocysteine hydrolase 1 item
  420. Rho-kinase 1 item
  421. tropomyosin receptor kinase 1 item
  422. LSD 1 item
  423. DDX3 1 item
  424. PRMT 1 item
  425. ACE 1 item
  426. GLP 1 item
  427. SK 1 item
  428. MST 1 item
  429. PPK 1 item
  430. c-Syk 1 item
  431. CDK1/CyclinB 1 item
  432. NHE 1 item
  433. IDO 2item
  434. Tph 1 item
  435. PIM1 kinase 1 item
  436. phospholipase A2 1 item
  437. reverse transcriptase 1 item
  438. GABAA receptor 1 item
  439. epoxide hydrolase 1 item
  440. Serotonin (5-HT) reuptake 1 item
  441. Cholesterol absorption 1 item
  442. Vascular Disrupting Agents (VDA) 1 item
  443. Androgen Receptor 1 item
  444. Substance P/NK1 Receptor 1 item
  445. gp120/CD4 1 item
  446. ATM 1 item
  447. Sirtuin 1 item
  448. NE 1 item
  449. CRF1 Receptors 1 item
  450. PIKfyve 1 item
  451. Bax 1 item
  452. Glycogen Phosphorylases 1 item
  453. MTH1 1 item
  454. PTEN 1 item
  455. Insulin Receptor 1 item
  456. NS3/4a Proteases 1 item
  457. p90 S6K 1 item
Related Disease
  1. Acne 1 item
  2. Acute Kidney Injury 3item
  3. Acute Lung Injury 1 item
  4. Acute Myelogenous Leukemia 4item
  5. Acute Myeloid Leukemia 19item
  6. Acute Renal Failure 1 item
  7. Adrenocortical Carcinoma 3item
  8. Bacterial Infectios 1 item
  9. Biliary Cancer 1 item
  10. Bladder Cancer 9item
  11. Bladder Carcinoma 3item
  12. Bladder Diseases 2item
  13. B-lymphoid Malignancies 1 item
  14. Brain Injuries Studies 3item
  15. Breast Cancer 75item
  16. Cancer 363item
  17. Castration-resistant Prostate Cancer 1 item
  18. Cervical Cancer 4item
  19. Cholangiocarcinoma 1 item
  20. Chronic Lymphocytic Leukemia 6item
  21. Chronic Myeloproliferative Disorders 1 item
  22. Clear Cell Renal Cell Carcinoma 1 item
  23. Cocaine-Related Disorders 2item
  24. Colon Cancer 23item
  25. Colon Carcinoma 3item
  26. Colorectal Cancer 28item
  27. Depression 2item
  28. Diabetes 7item
  29. Diffuse Large B-cell Lymphoma 1 item
  30. Dyskinesia 1 item
  31. Dyslipidemia 2item
  32. Epilepsy 3item
  33. Erectile Dysfunction 3item
  34. Friedreich's Ataxia 2item
  35. Fungi 1 item
  36. Glioblastoma 19item
  37. Glioma 11item
  38. HCV 3item
  39. Heart Failure 6item
  40. Hepatitis C 3item
  41. Hepatocellular Carcinoma 5item
  42. HIV 11item
  43. HIV Infections 11item
  44. Hypercholesterolemia 1 item
  45. Inflammation 1 item
  46. Inflammatory Diseases 7item
  47. Influenza 1 item
  48. Kidney Injury Studies 3item
  49. Leukemia 19item
  50. Liver Cancer 2item
  51. Lung Cancer 22item
  52. Lung Carcinoma 2item
  53. Lymphoma 26item
  54. Mantle Cell Lymphoma 2item
  55. Melanoma 20item
  56. Mixed Lineage Leukemia 1 item
  57. Multidrug Resistance Studies 1 item
  58. Multiple Myeloma 16item
  59. Myelofibrosis 2item
  60. Myeloma 2item
  61. Narcolepsy 1 item
  62. Neuroblastoma 7item
  63. Neurocognitive Disorders 1 item
  64. Neuronal Protection 1 item
  65. Non-small Cell Lung Cancer 15item
  66. Non-small Cell Lung Carcinoma 1 item
  67. Obsessive-Compulsive Disorder 1 item
  68. Osteoporosis 2item
  69. Ovarian Cancer 22item
  70. Pancreatic Cancer 31item
  71. Pancreatic Carcinoma 1 item
  72. Pentacyclic Triterpenoid 1 item
  73. Prostate Cancer 37item
  74. Psoriasis 3item
  75. Psoriasis Vulgaris 1 item
  76. Pulmonary Fibrosis 2item
  77. Renal Cancer 3item
  78. Renal Cell Carcinoma 4item
  79. Rheumatoid Arthritis 11item
  80. Sarcoma 1 item
  81. Schizophrenia 6item
  82. Sleep Disorders 2item
  83. Soft Tissue Sarcoma 1 item
  84. Squamous Cell Carcinoma 2item
  85. Thyroid Cancer 4item
  86. Tuberculosis 3item
  87. Type 2 Diabetes 12item