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  • Search results for: 'btk inhibitor 1'

Search results for: 'btk inhibitor 1'

Items 111-120 of 837

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  1. Avasimibe
    A4318 Avasimibe
    Target: Acyl coenzyme A: cholesterol acyltransferases
    Summary: ACAT inhibitor,orally bioavailable
      ≥25.09 mg/mL
  2. Isosafrole
    A8703 Isosafrole
    Target: Lactate Dehydrogenases (LDH)
    Summary: A stiripentol analog, a potent LDH inhibitor.
  3. RO4929097
    A4005 RO4929097
     1 Citation
    Summary: γ secretase inhibitor
      ≥23.47 mg/mL
  4. Anastrozole
    B1382 Anastrozole
    Target: Aromatases
    Summary: Aromatase inhibitor
      insoluble in H2O; ≥14.15 mg/mL
  5. DMOG
    A4506 DMOG
    Target: Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs)
    Summary: Competitive HIF-PH inhibitor, cell-permeable
  6. BIBR 1532
    A1945 BIBR 1532
     2 Citation
    Target: telomerase
    Summary: Telomerase inhibitor,novel and selective
      insoluble in H2O; ≥15.65 mg/mL
  7. U-104
    A4358 U-104
    Target: Carbonic Anhydrases
    Summary: CAIX inhibitor
      insoluble in H2O; ≥11.5 mg/mL
  8. PI-3065
    B4660 PI-3065
    Target: PI3K
    Summary: P110δkinase inhibitor
      ≥22.7 mg/mL
  9. U0126-EtOH
    A1337 U0126-EtOH
     10 Citation
    Target: MEK
    Summary: MEK1/2 inhibitor
      ≥21.33 mg/mL
  10. PP242
    A8318 PP242
    Target: mTOR
    Summary: MTOR inhibitor, selective and ATP-competitive

Items 111-120 of 837

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Category
  1. Proteases 79item
  2. Apoptosis 44item
  3. Chromatin/Epigenetics 106item
  4. Metabolism 63item
  5. MAPK Signaling 46item
  6. Tyrosine Kinase 114item
  7. DNA Damage/DNA Repair 62item
  8. PI3K/Akt/mTOR Signaling 62item
  9. Microbiology & Virology 31item
  10. Cell Cycle/Checkpoint 76item
  11. Ubiquitination/ Proteasome 33item
  12. JAK/STAT Signaling 33item
  13. TGF-β / Smad Signaling 34item
  14. Angiogenesis 9item
  15. GPCR/G protein 33item
  16. Stem Cell 31item
  17. Membrane Transporter/Ion Channel 31item
  18. Endocrinology and Hormones 12item
  19. Neuroscience 29item
  20. Obesity, Appetite Control & Diabetes 1 item
  21. Other Signal Transduction 2item
  22. Others 67item
  23. Immunology/Inflammation 15item
  24. Cardiovascular 1 item
Reversibility
  1. Reversible 54item
  2. Irreversible 25item
Target
  1. Caspases 11item
  2. Cyclin-Dependent Kinases 26item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 11item
  5. Cathepsins 11item
  6. Histone Deacetylases (HDACs) 27item
  7. Inhibitor of apoptosis proteins (IAP) 3item
  8. Akt 6item
  9. Bcl-2 6item
  10. PI3K 27item
  11. CXCR 4item
  12. Raf 10item
  13. Aurora Kinases 14item
  14. Bcl-xl 3item
  15. CSF-1R 2item
  16. Glycoproteins 1 item
  17. p97 1 item
  18. Gap Junctions 1 item
  19. MDM2 1 item
  20. EZH2 6item
  21. mTOR 15item
  22. Bromodomains 5item
  23. AP-1 3item
  24. MMP 10item
  25. Thymidine Phosphorylases 1 item
  26. Androgen Receptors 4item
  27. Peptidylprolyl isomerases 1 item
  28. Acyl coenzyme A: cholesterol acyltransferases 1 item
  29. Myosin II ATPases 1 item
  30. DT-diaphorases 1 item
  31. MER 1 item
  32. FLT3 12item
  33. GSK-3 9item
  34. Factor Xa 3item
  35. LPA Receptors 1 item
  36. P-glycoprotein (P-gp) 5item
  37. PLK 7item
  38. Chk 8item
  39. ULK1 1 item
  40. Eph Receptors 3item
  41. VEGFR 25item
  42. PDGFR 19item
  43. c-Kit 7item
  44. RET 3item
  45. IRAK 3item
  46. Bromodomain-containing proteins(BRDs) 1 item
  47. Phosphodiesterases (PDEs) 10item
  48. Mcl-1 5item
  49. Hydrolase 1 item
  50. Thymidylate Synthase 2item
  51. p38 9item
  52. PKB 1 item
  53. 3-phosphoglycerate dehydrogenase 1 item
  54. JNK 6item
  55. SGK 2item
  56. Bcr-Abl 10item
  57. Kynurenine-3-monooxygenase 1 item
  58. MEK 15item
  59. PORCN 1 item
  60. DOT1L 3item
  61. FGFR 9item
  62. Nrf2 1 item
  63. Insulin-like growth factor receptors(IGFRs) 1 item
  64. CGRP receptors 1 item
  65. Pim 4item
  66. Glucagon-like peptide 1 (GLP-1) receptors 2item
  67. Sir2-like Family Deacetylases (Sirtuins) 2item
  68. Deubiquitinating enzymes (DUBs) 4item
  69. PP1 1 item
  70. PP2A 1 item
  71. Smoothened 4item
  72. Eukaryotic elongation factors 1 item
  73. Ribosomal s6 kinases (RSK) 1 item
  74. Neuraminidases (NA) 1 item
  75. MET 7item
  76. Src 9item
  77. Trk Receptors 5item
  78. Integrins 1 item
  79. Aminopeptidases 2item
  80. STAT 5item
  81. ATP Citrate Lyases 1 item
  82. Microtubules/Tubulins 5item
  83. EGFR 15item
  84. Hedgehog 1 item
  85. Reverse Transcriptases 1 item
  86. ROCK 7item
  87. BTK 2item
  88. RIP kinases 1 item
  89. PAK 3item
  90. Hypoxia Inducible Factors (HIFs) 2item
  91. Tankyrases 1 item
  92. Inositol Phosphatases 1 item
  93. FAK 5item
  94. BMP and Other Activin Receptors 4item
  95. JAK 13item
  96. p300 1 item
  97. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  98. Syk 7item
  99. Progesterone Receptors 1 item
  100. EZH1 2item
  101. DNA-PK 6item
  102. HSP90 10item
  103. AMPK 2item
  104. Gutathione S-transferase 1 item
  105. CCR 2item
  106. PDHK 1 item
  107. Angiotensin AT2 Receptors 1 item
  108. eIF4E/eIF3G interaction 1 item
  109. Notch 1 item
  110. S-nitrosoglutathione reductase 1 item
  111. CFTR 2item
  112. TNKS 1 item
  113. Topoisomerases 7item
  114. Cytochrome P450 (CYP450) 6item
  115. thrombin 1 item
  116. Ksp 1 item
  117. Ribosomes 1 item
  118. Renin 2item
  119. HIV proteases 1 item
  120. Pepsins 1 item
  121. Influenza viruses 1 item
  122. ErbB 2item
  123. Ferroptosis 1 item
  124. S6 kinases 1 item
  125. Toll-like receptors (TLRs) 2item
  126. Adenosine Kinases 2item
  127. Actin 1 item
  128. DNA Methyltransferases 4item
  129. Survivin 1 item
  130. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  131. ERK 5item
  132. HMG-CoA Reductases 5item
  133. Vacuolar-type ATPase 1 item
  134. c-MET 8item
  135. BMI-1 1 item
  136. PKC 7item
  137. Calpains 5item
  138. Ubiquitin-specific proteases 1 item
  139. HCV Proteases 3item
  140. Ca2 /calmodulin-dependent protein kinases (CaMKs) 7item
  141. MLK3 1 item
  142. SMYD2 1 item
  143. CREBBP 2item
  144. EP300 2item
  145. Protease-Activated Receptors 1 item
  146. Lyn 1 item
  147. SGLT 1 item
  148. RAD51 1 item
  149. Trypsins 1 item
  150. HER2 2item
  151. Pyk2 3item
  152. USP 2item
  153. 5-HT2 Receptors 6item
  154. LRRK2 4item
  155. Calcium chelator 1 item
  156. DGAT 2item
  157. Insulin and Insulin-like Receptors 3item
  158. PARP 4item
  159. CB1 Receptors 1 item
  160. Pyruvate dehydrogenases (PDH) 1 item
  161. ALK 5item
  162. ROS1 2item
  163. Sphingosine kinases (SphKs) 2item
  164. Trypsin 1 item
  165. Chymotrypsin 1 item
  166. Kallikrein 1 item
  167. Trypsinogen 1 item
  168. KRAS G12C 1 item
  169. GTPases 1 item
  170. Monocarboxylate transporters (MCTs) 1 item
  171. CETP 2item
  172. Dehydrogenase 1 item
  173. PKG 1 item
  174. PKA 1 item
  175. Myosin light chain kinases (MLCKs) 2item
  176. GPR30 1 item
  177. HIV-1 gp120 1 item
  178. D1 and D5 Receptors 1 item
  179. D2 Receptors 4item
  180. D3 Receptors 2item
  181. 5-HT1 Receptors 2item
  182. 5-HT7 Receptors 1 item
  183. CaM-KK 1 item
  184. Valosin-containing protein (VCP) 1 item
  185. MELK 1 item
  186. Serotonin reuptake 1 item
  187. Insulin-like growth factors (IGFs) 1 item
  188. Clk 1 item
  189. TBK1 1 item
  190. MARK1 1 item
  191. NUAK1 2item
  192. Integrin-ligand interactions 1 item
  193. CSF1R 1 item
  194. Bromodomain and Extra-Terminal motif (BET) 1 item
  195. NUAK2 1 item
  196. Na /H Exchangers (NHEs) 1 item
  197. Lactate Dehydrogenases (LDH) 2item
  198. MK2 3item
  199. Fatty-acid-binding proteins (FABPs) 1 item
  200. Angiotensin-Converting Enzymes (ACEs) 2item
  201. Tie-2 4item
  202. RSK 2item
  203. p70 S6K 1 item
  204. Free Fatty Acid Receptors 1 item
  205. phosphatases 1 item
  206. Autophagy 2item
  207. ATM/ATR 7item
  208. Mixed lineage kinase domain-like protein (MLKL) 1 item
  209. COX 6item
  210. Heparanases 1 item
  211. YAP 1 item
  212. CK1 1 item
  213. IDH2 1 item
  214. CK2 3item
  215. HIPK2 1 item
  216. HIPK3 1 item
  217. HIV Integrases 1 item
  218. Cryptochromes 1 item
  219. G-quadruplexes 1 item
  220. Squalene epoxidases 2item
  221. PRAK 1 item
  222. MAPKAP-K2 1 item
  223. Delayed rectifier outward potassium current (IKr) 1 item
  224. 20S proteasomal chymotrypsin 1 item
  225. Geranylgeranyltransferase I 1 item
  226. Farnesyltransferase 1 item
  227. NAT10 1 item
  228. Nampt 2item
  229. eIF4F 1 item
  230. Cdc42 1 item
  231. SRPK1 1 item
  232. P2X Receptors 2item
  233. Glutaminases 1 item
  234. Carbonic Anhydrases 5item
  235. Ron 1 item
  236. AP endonucleases 1 item
  237. G9a 2item
  238. BLM 1 item
  239. HSV 2item
  240. NADPH Oxidases 2item
  241. Calcium-activated chloride channels (CaCC) 1 item
  242. GPR35 1 item
  243. Aldehyde Dehydrogenases 2item
  244. Synthases/Synthetases 3item
  245. MAGL 1 item
  246. c-Fyn 1 item
  247. Leukotriene and Related Receptors 1 item
  248. TAK1 1 item
  249. Histamine H1 Receptors 2item
  250. Na /K ATPases 2item
  251. P110 1 item
  252. Hck 1 item
  253. Inositol-requiring enzyme 1 (IRE1) 1 item
  254. SETD7 1 item
  255. Na /K /Cl- Symporters (NKCCs) 1 item
  256. GABAA Receptors 1 item
  257. Phospholipases 1 item
  258. TRP Channel 2item
  259. RNA Polymerases 2item
  260. Norepinephrine transporter 1 item
  261. 5-HT Transporters 3item
  262. Xanthine oxidoreductases 1 item
  263. Dihydroorotate dehydrogenase 1 item
  264. Guanylyl Cyclases 1 item
  265. Histone Demethylases 1 item
  266. MNK 1 item
  267. NO Donors / Precursors 1 item
  268. CB2 Receptors 1 item
  269. HIV-1 reverse transcriptase 1 item
  270. IL Receptors 2item
  271. CCL2 1 item
  272. Norepinephrine transporters 1 item
  273. 15-lipoxygenases 1 item
  274. Calcium-Activated Potassium (KCa) Channels 1 item
  275. AChE 2item
  276. Insulin Receptors 1 item
  277. IRG-1R 1 item
  278. Proton Pump 1 item
  279. cAMP 1 item
  280. Sulfonylurea receptors 1 item
  281. eEF-2 1 item
  282. Inward Rectifier Potassium (Kir) Channels 3item
  283. Arp2/3 complex 1 item
  284. CRTH2 1 item
  285. Cdc7 1 item
  286. Nuclear Receptors 1 item
  287. CMV 1 item
  288. ZAP-70 1 item
  289. Catechol O-Methyltransferase (COMT) 2item
  290. fibrinolysis 1 item
  291. Angiotensin AT1 Receptors 2item
  292. D4 Receptors 1 item
  293. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  294. HBV Proteases 1 item
  295. Flk-1 1 item
  296. Papains 1 item
  297. Protein Arginine Methyltransferases 1 item
  298. IMPDH 1 item
  299. Na /Ca2 Exchangers (NCXs) 1 item
  300. NAE 2item
  301. Ubiquitin-activating Enzyme E1 1 item
  302. SUMOylation 1 item
  303. ATGL 1 item
  304. BACE 1 item
  305. Cytidine deaminases 1 item
  306. angiogenesis 1 item
  307. Glucagon Receptors 1 item
  308. 15-PGDH 1 item
  309. DPP-4 4item
  310. PP4 1 item
  311. c-RET 1 item
  312. Nonstructural protein 5B (NS5B) 1 item
  313. ETA Receptors 2item
  314. ETB Receptors 1 item
  315. p70 rsk 1 item
  316. FPTase 1 item
  317. ADAMs 1 item
  318. TAM kinase 1 item
  319. p53-MDM2 interaction 1 item
  320. nuclear export 1 item
  321. CRM1 1 item
  322. AXL 1 item
  323. Protein polybromo-1 1 item
  324. SMARCA4 1 item
  325. SMARCA2 1 item
  326. Dipeptidyl-peptidase II 1 item
  327. HDAC 1 item
  328. c-Fms tyrosine kinase 1 item
  329. human lyase 1 item
  330. Ub-conjugating enzyme (E2) complex 1 item
  331. STK 1 item
  332. IKK 1 item
  333. MSK 1 item
  334. HCV polymerase 2item
  335. Ftase 1 item
  336. PC-PLC 1 item
  337. Elastases 1 item
  338. P97 ATPase 1 item
  339. NTPDases 1 item
  340. telomerase 1 item
  341. Histone Acetyltransferases (HATs) 1 item
  342. F1 Fo-ATPase 1 item
  343. ITK 1 item
  344. NOD1 1 item
  345. NUAK 1 item
  346. DCLK2 1 item
  347. FAAH 1 item
  348. TYK2 1 item
  349. Lck 1 item
  350. Aromatases 1 item
  351. PKD 1 item
  352. SHIP 1 item
  353. MCL1 1 item
  354. Bcl-w 1 item
  355. tropomyosin receptor kinase 1 item
  356. LSD 1 item
  357. PRMT 1 item
  358. GLP 1 item
  359. SK 1 item
  360. MST 1 item
  361. IDO 1 item
  362. Serotonin (5-HT) reuptake 1 item
  363. Androgen Receptor 1 item
  364. Substance P/NK1 Receptor 1 item
  365. gp120/CD4 1 item
  366. ATM 2item
  367. Sirtuin 1 item
  368. NE 1 item
  369. PIKfyve 1 item
  370. Glycogen Phosphorylases 1 item
  371. MTH1 1 item
  372. Insulin Receptor 1 item
Reported Experiments
  1. Animal Experiments 715item
  2. Cell Experiments 488item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acne 1 item
  3. Acute Disseminated Candidiasis 1 item
  4. Acute Kidney Injury 1 item
  5. Acute Lung Injury 1 item
  6. Acute Myelogenous Leukemia 6item
  7. Acute Myeloid Leukemia 27item
  8. Acute Renal Failure 1 item
  9. Adrenocortical Carcinoma 4item
  10. Advanced Renal Cell Carcinoma 1 item
  11. Autoimmune Diseases 1 item
  12. Biliary Cancer 1 item
  13. Bladder Cancer 10item
  14. Bladder Carcinoma 4item
  15. Bladder Diseases 2item
  16. B-lymphoid Malignancies 1 item
  17. Brain Injuries Studies 3item
  18. Breast Cancer 119item
  19. Cancer 445item
  20. Candida Peritonitis 1 item
  21. Candidemia 1 item
  22. Castration-resistant Prostate Cancer 1 item
  23. Cervical Cancer 5item
  24. Cholangiocarcinoma 2item
  25. Chronic Lymphocytic Leukemia 8item
  26. Chronic Myeloproliferative Disorders 1 item
  27. Clear Cell Renal Cell Carcinoma 2item
  28. Cocaine-Related Disorders 2item
  29. Colon Cancer 45item
  30. Colon Carcinoma 7item
  31. Colorectal Cancer 42item
  32. Depression 2item
  33. Diabetes 8item
  34. Diffuse Large B-cell Lymphoma 1 item
  35. Dyskinesia 1 item
  36. Dyslipidemia 2item
  37. Epilepsy 2item
  38. Erectile Dysfunction 3item
  39. Friedreich's Ataxia 1 item
  40. Fungal Infection 1 item
  41. Glioblastoma 35item
  42. Glioma 18item
  43. HCV 3item
  44. Heart Failure 1 item
  45. Hepatic Cancer 2item
  46. Hepatitis C 3item
  47. Hepatocellular Carcinoma 8item
  48. HIV 5item
  49. HIV Infections 11item
  50. Hypercholesterolemia 2item
  51. Immunological Diseases 1 item
  52. Inflammation 1 item
  53. Inflammatory Bowel Disease 1 item
  54. Inflammatory Diseases 16item
  55. Influenza 2item
  56. Kidney Injury Studies 1 item
  57. Leukemia 23item
  58. Liver Cancer 3item
  59. Lung Cancer 43item
  60. Lung Carcinoma 4item
  61. Lymphoma 31item
  62. Mantle Cell Lymphoma 2item
  63. Medulloblastoma 1 item
  64. Melanoma 38item
  65. Mixed Lineage Leukemia 3item
  66. Multiple Myeloma 23item
  67. Myelofibrosis 2item
  68. Myeloma 7item
  69. Neuroblastoma 14item
  70. Neurocognitive Disorders 1 item
  71. Neuronal Protection 1 item
  72. Non-small Cell Lung Cancer 26item
  73. Non-small Cell Lung Carcinoma 2item
  74. Obsessive-Compulsive Disorder 1 item
  75. Osteoporosis 2item
  76. Ovarian Cancer 35item
  77. Pancreatic Cancer 48item
  78. Pancreatic Carcinoma 3item
  79. Prostate Cancer 57item
  80. Psoriasis 4item
  81. Psoriasis Vulgaris 1 item
  82. Pulmonary Arterial Hypertension 2item
  83. Pulmonary Fibrosis 2item
  84. Renal Cancer 4item
  85. Renal Cell Carcinoma 8item
  86. Rheumatoid Arthritis 14item
  87. Sarcoma 1 item
  88. Schizophrenia 7item
  89. Sleep Disorders 1 item
  90. Soft Tissue Sarcoma 1 item
  91. Squamous Cell Carcinoma 2item
  92. Testicular Cancer 2item
  93. Thyroid Cancer 6item
  94. Tuberculosis 1 item
  95. Type 2 Diabetes 17item