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  • Search results for: 'btk inhibitor 1'

Search results for: 'btk inhibitor 1'

Items 321-330 of 1009

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  1. Enzastaurin (LY317615)
    A1670 Enzastaurin (LY317615)
     2 Citation
    Target: PKC
    Summary: PKC beta inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥8.59 mg/mL
  2. S-Ruxolitinib (INCB018424)
    A4149 S-Ruxolitinib (INCB018424)
    Target: JAK
    Summary: JAK1/2 inhibitor,potent and selective
      Soluble in DMSO
  3. RG7112
    A3762 RG7112
     5 Citation
    Target: MDM2
    Summary: MDM2 inhibitor, first clinical
      ≥36.4 mg/mL
  4. Axitinib (AG 013736)
    A8370 Axitinib (AG 013736)
     1 Citation
    Target: VEGFR|PDGFR|c-Kit
    Summary: VEGFR1/ c-Kit inhibitor
      insoluble in H2O; ≥19.3 mg/mL
  5. BMS-378806
    B1533 BMS-378806
     1 Citation
    Target: gp120/CD4
    Summary: Gp120/CD4 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥20.2 mg/mL
  6. Simeprevir
    A3820 Simeprevir
     1 Citation
    Target: HCV Proteases
    Summary: Inhibitor of HCV NS3/4A protease
      insoluble in H2O; insoluble in EtOH; ≥18.75 mg/mL
  7. Celastrol
    A2604 Celastrol
    Target: Proteasome
    Summary: Antioxidant, anti-inflammatory and immunosuppressive agent
      ≥22.55 mg/mL
  8. Piroxicam
    A8503 Piroxicam
    Target: COX|Prostaglandin synthesis
    Summary: Prostaglandin synthesis/Coxinhibitor
      insoluble in H2O; insoluble in EtOH; ≥16.57 mg/mL
  9. NPPB
    B6367 NPPB
    Target: Calcium-activated chloride channels (CaCC)|GPR35
    Summary: inhibitor of chloride channel
      insoluble in EtOH; insoluble in H2O; ≥11.05 mg/mL
  10. CVT-313
    A3336 CVT-313
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Cdk2 inhibitor
      ≥20 mg/mL

Items 321-330 of 1009

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Category
  1. Proteases 89item
  2. Apoptosis 57item
  3. Chromatin/Epigenetics 119item
  4. Metabolism 93item
  5. MAPK Signaling 47item
  6. Tyrosine Kinase 138item
  7. DNA Damage/DNA Repair 79item
  8. PI3K/Akt/mTOR Signaling 79item
  9. Microbiology & Virology 46item
  10. Cell Cycle/Checkpoint 84item
  11. Ubiquitination/ Proteasome 29item
  12. JAK/STAT Signaling 45item
  13. TGF-β / Smad Signaling 42item
  14. Angiogenesis 8item
  15. GPCR/G protein 43item
  16. Stem Cell 36item
  17. Membrane Transporter/Ion Channel 33item
  18. Endocrinology and Hormones 19item
  19. Neuroscience 43item
  20. Obesity, Appetite Control & Diabetes 1 item
  21. Other Signal Transduction 3item
  22. Others 75item
  23. Immunology/Inflammation 19item
  24. Cardiovascular 3item
  25. Vitamin D Related 2item
  26. NF-κB 1 item
Specificity
  1. Selective 715item
  2. Non-Selective 5item
Reversibility
  1. Reversible 55item
  2. Irreversible 31item
Target
  1. Caspases 9item
  2. Cyclin-Dependent Kinases 25item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 12item
  5. Cathepsins 9item
  6. Histone Deacetylases (HDACs) 32item
  7. Inhibitor of apoptosis proteins (IAP) 3item
  8. Akt 13item
  9. Bcl-2 9item
  10. PI3K 36item
  11. CXCR 4item
  12. Raf 13item
  13. Aurora Kinases 20item
  14. Bcl-xl 2item
  15. CSF-1R 4item
  16. Glycoproteins 1 item
  17. p97 1 item
  18. Gap Junctions 1 item
  19. MDM2 2item
  20. EZH2 4item
  21. mTOR 20item
  22. Bromodomains 6item
  23. AP-1 3item
  24. MMP 8item
  25. Thymidine Phosphorylases 1 item
  26. Androgen Receptors 5item
  27. Peptidylprolyl isomerases 1 item
  28. Acyl coenzyme A: cholesterol acyltransferases 1 item
  29. Myosin II ATPases 1 item
  30. DT-diaphorases 1 item
  31. Voltage-gated Potassium (KV) Channels 1 item
  32. MER 1 item
  33. FLT3 19item
  34. GSK-3 10item
  35. Factor Xa 4item
  36. LPA Receptors 3item
  37. P-glycoprotein (P-gp) 5item
  38. PLK 10item
  39. Chk 7item
  40. Eph Receptors 2item
  41. VEGFR 40item
  42. PDGFR 25item
  43. c-Kit 13item
  44. RET 4item
  45. IRAK 1 item
  46. Bromodomain-containing proteins(BRDs) 1 item
  47. Phosphodiesterases (PDEs) 16item
  48. Mcl-1 6item
  49. Hydrolase 1 item
  50. Thymidylate Synthase 3item
  51. p38 10item
  52. PKB 1 item
  53. JNK 4item
  54. SGK 1 item
  55. Bcr-Abl 13item
  56. Kynurenine-3-monooxygenase 1 item
  57. MEK 13item
  58. PORCN 1 item
  59. DOT1L 3item
  60. FGFR 17item
  61. Nrf2 2item
  62. Insulin-like growth factor receptors(IGFRs) 1 item
  63. CGRP receptors 1 item
  64. Pim 3item
  65. Liver X receptors (LXRs) 1 item
  66. Glucagon-like peptide 1 (GLP-1) receptors 2item
  67. Sir2-like Family Deacetylases (Sirtuins) 3item
  68. Voltage-gated Sodium (NaV) Channels 1 item
  69. Deubiquitinating enzymes (DUBs) 3item
  70. PP1 1 item
  71. PP2A 1 item
  72. Smoothened 4item
  73. Eukaryotic elongation factors 1 item
  74. Neuraminidases (NA) 2item
  75. MET 7item
  76. Src 14item
  77. Trk Receptors 6item
  78. Integrins 1 item
  79. Aminopeptidases 4item
  80. NMDA Receptors 2item
  81. STAT 8item
  82. ATP Citrate Lyases 1 item
  83. Microtubules/Tubulins 5item
  84. Estrogen and Related Receptors 2item
  85. EGFR 23item
  86. Hedgehog 1 item
  87. Reverse Transcriptases 5item
  88. ROCK 9item
  89. BTK 1 item
  90. RIP kinases 1 item
  91. PAK 3item
  92. Hypoxia Inducible Factors (HIFs) 2item
  93. Tankyrases 1 item
  94. Inositol Phosphatases 1 item
  95. FAK 6item
  96. BMP and Other Activin Receptors 3item
  97. JAK 20item
  98. p300 1 item
  99. Stearoyl-CoA 9-desaturase (SCD-1) 2item
  100. Syk 7item
  101. Progesterone Receptors 1 item
  102. EZH1 2item
  103. DNA-PK 7item
  104. HSP90 12item
  105. AMPK 2item
  106. Gutathione S-transferase 1 item
  107. CCR 2item
  108. PDHK 1 item
  109. Angiotensin AT2 Receptors 1 item
  110. Notch 1 item
  111. S-nitrosoglutathione reductase 1 item
  112. CFTR 2item
  113. TNKS 1 item
  114. Topoisomerases 13item
  115. Cytochrome P450 (CYP450) 10item
  116. thrombin 1 item
  117. Ksp 2item
  118. Renin 1 item
  119. Influenza viruses 1 item
  120. ErbB 5item
  121. S6 kinases 1 item
  122. Toll-like receptors (TLRs) 4item
  123. Adenosine Kinases 2item
  124. Serine Proteases 2item
  125. DNA Methyltransferases 4item
  126. Survivin 1 item
  127. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  128. ERK 7item
  129. HMG-CoA Reductases 6item
  130. c-MET 8item
  131. BMI-1 1 item
  132. PKC 14item
  133. Calpains 5item
  134. Ubiquitin-specific proteases 1 item
  135. M1 Receptors 1 item
  136. HCV Proteases 3item
  137. Ca2 /calmodulin-dependent protein kinases (CaMKs) 6item
  138. MLK3 1 item
  139. CREBBP 1 item
  140. EP300 1 item
  141. Protease-Activated Receptors 1 item
  142. Lyn 2item
  143. SGLT 1 item
  144. RAD51 2item
  145. Trypsins 1 item
  146. HER2 3item
  147. Pyk2 3item
  148. 5-HT2 Receptors 6item
  149. LRRK2 6item
  150. Voltage-gated Calcium Channels (CaV) 1 item
  151. Calcium chelator 1 item
  152. DGAT 2item
  153. Insulin and Insulin-like Receptors 4item
  154. PARP 6item
  155. CB1 Receptors 2item
  156. Pyruvate dehydrogenases (PDH) 2item
  157. ALK 9item
  158. ROS1 2item
  159. Sphingosine kinases (SphKs) 3item
  160. Trypsin 1 item
  161. Chymotrypsin 1 item
  162. Kallikrein 1 item
  163. Trypsinogen 1 item
  164. Monocarboxylate transporters (MCTs) 2item
  165. CETP 2item
  166. Dehydrogenase 1 item
  167. PKG 2item
  168. PKA 6item
  169. Myosin light chain kinases (MLCKs) 2item
  170. GPR30 1 item
  171. HIV-1 gp120 1 item
  172. D1 and D5 Receptors 1 item
  173. D2 Receptors 4item
  174. D3 Receptors 2item
  175. 5-HT1 Receptors 2item
  176. 5-HT7 Receptors 1 item
  177. MELK 1 item
  178. Serotonin reuptake 1 item
  179. Insulin-like growth factors (IGFs) 1 item
  180. CSF1R 1 item
  181. Bromodomain and Extra-Terminal motif (BET) 1 item
  182. Lactate Dehydrogenases (LDH) 2item
  183. MK2 2item
  184. Fatty-acid-binding proteins (FABPs) 1 item
  185. Angiotensin-Converting Enzymes (ACEs) 4item
  186. Tie-2 5item
  187. RSK 3item
  188. p70 S6K 1 item
  189. Free Fatty Acid Receptors 1 item
  190. phosphatases 1 item
  191. Autophagy 4item
  192. ATM/ATR 5item
  193. COX 11item
  194. YAP 1 item
  195. CK1 1 item
  196. CK2 3item
  197. HIPK2 1 item
  198. HIPK3 1 item
  199. HIV Integrases 1 item
  200. Squalene epoxidases 2item
  201. PRAK 1 item
  202. MAPKAP-K2 1 item
  203. Delayed rectifier outward potassium current (IKr) 1 item
  204. 20S proteasomal chymotrypsin 1 item
  205. Geranylgeranyltransferase I 1 item
  206. Farnesyltransferase 1 item
  207. Nampt 3item
  208. eIF4F 1 item
  209. Cdc42 1 item
  210. SRPK1 1 item
  211. P2X Receptors 2item
  212. Glutaminases 2item
  213. Carbonic Anhydrases 6item
  214. Ron 1 item
  215. G9a 1 item
  216. BLM 1 item
  217. HSV 2item
  218. NADPH Oxidases 3item
  219. Calcium-activated chloride channels (CaCC) 1 item
  220. GPR35 1 item
  221. Aldehyde Dehydrogenases 2item
  222. Synthases/Synthetases 2item
  223. MAGL 1 item
  224. Leukotriene and Related Receptors 1 item
  225. Histamine H1 Receptors 3item
  226. Na /K ATPases 2item
  227. P110 1 item
  228. Hck 2item
  229. Inositol-requiring enzyme 1 (IRE1) 1 item
  230. Na /K /Cl- Symporters (NKCCs) 2item
  231. GABAA Receptors 1 item
  232. Phospholipases 1 item
  233. TRP Channel 2item
  234. RNA Polymerases 2item
  235. Norepinephrine transporter 1 item
  236. 5-HT Transporters 3item
  237. Xanthine oxidoreductases 1 item
  238. Dihydroorotate dehydrogenase 1 item
  239. Guanylyl Cyclases 1 item
  240. Histone Demethylases 1 item
  241. MNK 2item
  242. 5-Lipoxygenases 1 item
  243. NO Donors / Precursors 1 item
  244. CB2 Receptors 1 item
  245. HIV-1 reverse transcriptase 1 item
  246. IL Receptors 2item
  247. CCL2 1 item
  248. Norepinephrine transporters 1 item
  249. 15-lipoxygenases 1 item
  250. Calcium-Activated Potassium (KCa) Channels 2item
  251. AChE 3item
  252. Insulin Receptors 1 item
  253. IRG-1R 1 item
  254. cAMP 1 item
  255. Sulfonylurea receptors 1 item
  256. eEF-2 1 item
  257. Inward Rectifier Potassium (Kir) Channels 2item
  258. CRTH2 1 item
  259. Cdc7 1 item
  260. Nuclear Receptors 1 item
  261. CMV 1 item
  262. ZAP-70 1 item
  263. Catechol O-Methyltransferase (COMT) 2item
  264. fibrinolysis 1 item
  265. Angiotensin AT1 Receptors 3item
  266. D4 Receptors 1 item
  267. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  268. NMDA receptor 1 item
  269. HBV Proteases 1 item
  270. Hydroxylases 2item
  271. Flk-1 1 item
  272. Papains 1 item
  273. Protein Arginine Methyltransferases 1 item
  274. IMPDH 1 item
  275. Na /Ca2 Exchangers (NCXs) 1 item
  276. NAE 2item
  277. Ubiquitin-activating Enzyme E1 2item
  278. SUMOylation 1 item
  279. ATGL 1 item
  280. BACE 1 item
  281. Cytidine deaminases 1 item
  282. angiogenesis 1 item
  283. Glucagon Receptors 1 item
  284. 15-PGDH 1 item
  285. DPP-4 5item
  286. PP4 1 item
  287. c-RET 3item
  288. Nonstructural protein 5B (NS5B) 1 item
  289. guanylyl cyclase 1 item
  290. ETA Receptors 2item
  291. ETB Receptors 1 item
  292. p70 rsk 3item
  293. voltage-gated chloride channels 1 item
  294. FPTase 1 item
  295. 5-HT1 Receptor 1 item
  296. Microtubule/Tubulin 1 item
  297. VEGFR3/FLT4 1 item
  298. NTRK1/TRKA 1 item
  299. CSF-1R/c-Fms 1 item
  300. Tryptophan hydroxylases (TPH) 2item
  301. ADAMs 1 item
  302. NMPRTase 1 item
  303. Bfl-1 1 item
  304. TAM kinase 1 item
  305. p53-MDM2 interaction 1 item
  306. nuclear export 1 item
  307. CRM1 1 item
  308. PTP 1 item
  309. KDR 2item
  310. Fyn kinase 1 item
  311. AXL 1 item
  312. Glyoxalase I 1 item
  313. Dipeptidyl-peptidase II 1 item
  314. p53 5item
  315. metalloprotease 1 item
  316. HDAC 2item
  317. Antifungal 1 item
  318. 5-HT receptors 1 item
  319. sodium channel 2item
  320. c-Fms tyrosine kinase 1 item
  321. human lyase 1 item
  322. insulin 1 item
  323. Ub-conjugating enzyme (E2) complex 1 item
  324. Smoothened receptor 1 item
  325. cysteine protease 2item
  326. PPAR 1 item
  327. IKK 1 item
  328. MSK 1 item
  329. gp120-CD4 interaction 1 item
  330. HCV polymerase 2item
  331. Ftase 1 item
  332. PC-PLC 2item
  333. Elastases 1 item
  334. ATP synthase 1 item
  335. Vitamin D receptors (VDRs) 1 item
  336. Antibiotic 2item
  337. Mer tyrosine kinase 1 item
  338. Hec1 1 item
  339. neprilysin 1 item
  340. GLI 1 item
  341. Stem Cell Differentiation 1 item
  342. PP2A/Nkd interaction 1 item
  343. HMGCR 1 item
  344. ErbB-2 1 item
  345. adrenergic receptor 2item
  346. HIV 1 item
  347. 5-HT4 Receptor 1 item
  348. TRPA 1 item
  349. sterol demethylase 1 item
  350. PDK-1 1 item
  351. GAPDH 1 item
  352. Histone Acetyltransferases (HATs) 2item
  353. complex I of the mitochondrial electron transport chain 1 item
  354. F1 Fo-ATPase 1 item
  355. Prk 1 item
  356. potassium channel 1 item
  357. calcium channel 1 item
  358. Ribonucleotide Reductases 1 item
  359. Trx 1 item
  360. Tyrosinases 1 item
  361. Neurokinin receptor 1 item
  362. HSP70 1 item
  363. ICAM 1 item
  364. ITK 1 item
  365. HIF-PH 1 item
  366. NUAK 1 item
  367. Rho 1 item
  368. Aryl hydrocarbon receptors (AHRs) 1 item
  369. Ubiquitin E3 Ligases 1 item
  370. DCLK2 1 item
  371. FAAH 1 item
  372. PTK 1 item
  373. integrase 1 item
  374. NOS 2item
  375. TYK2 2item
  376. MUSK 1 item
  377. MAP3K 1 item
  378. GPR3 1 item
  379. Adenosine Deaminases 2item
  380. mitochondrial pyruvate carrier (MPC) 1 item
  381. DNA gyrase 1 item
  382. prolactin secretion 1 item
  383. gonadotropin release 1 item
  384. DprE 1 item
  385. Vitamin D 1 item
  386. carnitine reabsorption 1 item
  387. Histamine receptors 1 item
  388. GluR 1 item
  389. 5-HT receptor 1 item
  390. dopamine receptors 1 item
  391. AMPA receptor 1 item
  392. 5-alpha Reductases 1 item
  393. Flk1 2item
  394. SAPK 1 item
  395. p21 1 item
  396. Prostaglandin synthesis 1 item
  397. Protein Tyrosine Phosphatases 1 item
  398. alkaline phosphatases 1 item
  399. ATPases 1 item
  400. glutamate release 1 item
  401. PAFR 1 item
  402. Aromatases 2item
  403. DHFR 1 item
  404. GARFT 1 item
  405. 5-HT 1 item
  406. FGR 1 item
  407. YES 2item
  408. Fyn 2item
  409. ARG 1 item
  410. Autotaxin 1 item
  411. UCH 1 item
  412. RHA 1 item
  413. HCV NS3-4A protease 1 item
  414. PKD 1 item
  415. Thioredoxin Reductases 1 item
  416. enoyl-acyl-carrier protein reductase 1 item
  417. SHIP 1 item
  418. MCL1 1 item
  419. Bcl-w 1 item
  420. glutathione peroxidase 4 1 item
  421. S-adenosylhomocysteine hydrolase 1 item
  422. Rho-kinase 1 item
  423. tropomyosin receptor kinase 1 item
  424. LSD 1 item
  425. DDX3 1 item
  426. PRMT 1 item
  427. ACE 1 item
  428. GLP 1 item
  429. SK 1 item
  430. MST 1 item
  431. PPK 1 item
  432. c-Syk 1 item
  433. CDK1/CyclinB 1 item
  434. NHE 1 item
  435. IDO 1 item
  436. Tph 1 item
  437. PIM1 kinase 1 item
  438. phospholipase A2 1 item
  439. reverse transcriptase 1 item
  440. epoxide hydrolase 1 item
  441. Serotonin (5-HT) reuptake 1 item
  442. Cholesterol absorption 1 item
  443. Vascular Disrupting Agents (VDA) 1 item
  444. Androgen Receptor 1 item
  445. Substance P/NK1 Receptor 1 item
  446. gp120/CD4 1 item
  447. ATM 1 item
  448. Sirtuin 1 item
  449. NE 1 item
  450. PIKfyve 1 item
  451. Bax 1 item
  452. Glycogen Phosphorylases 1 item
  453. MTH1 1 item
  454. PTEN 1 item
  455. Insulin Receptor 1 item
  456. NS3/4a Proteases 1 item
  457. Ca2 -ATPases 1 item
  458. p90 S6K 1 item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acne 1 item
  3. Acute Disseminated Candidiasis 1 item
  4. Acute Kidney Injury 2item
  5. Acute Lung Injury 1 item
  6. Acute Myelogenous Leukemia 5item
  7. Acute Myeloid Leukemia 26item
  8. Acute Renal Failure 1 item
  9. Adrenocortical Carcinoma 4item
  10. Advanced Renal Cell Carcinoma 1 item
  11. Autoimmune Diseases 1 item
  12. Biliary Cancer 1 item
  13. Bladder Cancer 11item
  14. Bladder Carcinoma 4item
  15. Bladder Diseases 2item
  16. B-lymphoid Malignancies 1 item
  17. Brain Injuries Studies 3item
  18. Breast Cancer 116item
  19. Cancer 514item
  20. Candida Peritonitis 1 item
  21. Candidemia 1 item
  22. Castration-resistant Prostate Cancer 1 item
  23. Cervical Cancer 6item
  24. Cholangiocarcinoma 2item
  25. Chronic Lymphocytic Leukemia 8item
  26. Chronic Myeloproliferative Disorders 1 item
  27. Clear Cell Renal Cell Carcinoma 2item
  28. Cocaine-Related Disorders 2item
  29. Colon Cancer 41item
  30. Colon Carcinoma 7item
  31. Colorectal Cancer 40item
  32. Depression 2item
  33. Diabetes 7item
  34. Diffuse Large B-cell Lymphoma 1 item
  35. Dyskinesia 1 item
  36. Dyslipidemia 2item
  37. Epilepsy 4item
  38. Erectile Dysfunction 4item
  39. Friedreich's Ataxia 1 item
  40. Fungal Infection 1 item
  41. Fungi 1 item
  42. Glioblastoma 33item
  43. Glioma 17item
  44. HCV 4item
  45. Heart Failure 5item
  46. Hepatic Cancer 2item
  47. Hepatitis C 4item
  48. Hepatocellular Carcinoma 8item
  49. HIV 14item
  50. HIV Infections 11item
  51. Hypercholesterolemia 3item
  52. Immunological Diseases 1 item
  53. Inflammation 1 item
  54. Inflammatory Bowel Disease 1 item
  55. Inflammatory Diseases 17item
  56. Influenza 3item
  57. Kidney Injury Studies 2item
  58. Leukemia 25item
  59. Liver Cancer 3item
  60. Lung Cancer 39item
  61. Lung Carcinoma 4item
  62. Lymphoma 28item
  63. Mantle Cell Lymphoma 2item
  64. Medulloblastoma 1 item
  65. Melanoma 35item
  66. Mixed Lineage Leukemia 3item
  67. Multiple Myeloma 21item
  68. Myelofibrosis 2item
  69. Myeloma 7item
  70. Neuroblastoma 14item
  71. Neurocognitive Disorders 1 item
  72. Neuronal Protection 1 item
  73. Non-small Cell Lung Cancer 26item
  74. Non-small Cell Lung Carcinoma 2item
  75. Obsessive-Compulsive Disorder 1 item
  76. Osteoporosis 2item
  77. Ovarian Cancer 34item
  78. Pancreatic Cancer 47item
  79. Pancreatic Carcinoma 3item
  80. Pentacyclic Triterpenoid 1 item
  81. Prostate Cancer 53item
  82. Psoriasis 4item
  83. Psoriasis Vulgaris 1 item
  84. Pulmonary Arterial Hypertension 2item
  85. Pulmonary Fibrosis 2item
  86. Renal Cancer 4item
  87. Renal Cell Carcinoma 8item
  88. Rheumatoid Arthritis 14item
  89. Sarcoma 1 item
  90. Schizophrenia 8item
  91. Sleep Disorders 1 item
  92. Soft Tissue Sarcoma 1 item
  93. Squamous Cell Carcinoma 2item
  94. Testicular Cancer 2item
  95. Thyroid Cancer 6item
  96. Tuberculosis 4item
  97. Type 2 Diabetes 16item