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  • Search results for: 'btk inhibitor 1'

Search results for: 'btk inhibitor 1'

Items 541-550 of 810

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  1. WEHI-539
    A3935 WEHI-539
     15 Citation
    Target: Bcl-xl
    Summary: Bcl-xL inhibitor,potent and selective
      insoluble in DMSO; insoluble in H2O; insoluble in EtOH
  2. UNC2025
    B8016 UNC2025
     1 Citation
    Target: MER|FLT3
    Summary: orally bioavailable dual MER/FLT3 inhibitor
      ≥23.85 mg/mL
  3. AZD-5438
    A8326 AZD-5438
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Potent CDK1/2/9 inhibitor
      insoluble in H2O; ≥18.55 mg/mL
  4. Zebularine
    A1915 Zebularine
     1 Citation
    Target: DNA Methyltransferases|Cytidine deaminases
    Summary: DNA methylation inhibitor
      insoluble in EtOH; ≥50.7 mg/mL
  5. ETP-46464
    A8626 ETP-46464
    Target: PI3K|mTOR|DNA-PK|ATM/ATR
    Summary: ATR inhibitor,potent and selective
      ≥16.13 mg/mL
  6. HG-10-102-01
    B1262 HG-10-102-01
     1 Citation
    Target: LRRK2
    Summary: LRRK2 inhibitor
      insoluble in H2O; ≥18.9 mg/mL
  7. Fostamatinib (R788)
    B2284 Fostamatinib (R788)
    Target: Syk
    Summary: Spleen tyrosine kinase (Syk) inhibitor
      insoluble in H2O; ≥100.4 mg/mL
  8. AS-252424
    B2180 AS-252424
    Target: Akt|PI3K
    Summary: PI3Kγ inhibitor,novel and potent
      insoluble in EtOH; insoluble in H2O; ≥30.5 mg/mL
  9. TG100713
    B2177 TG100713
    Target: PI3K
    Summary: pan-PI3K inhibitor
      soluble in DMSO
  10. Lapatinib
    A8218 Lapatinib
     2 Citation
    Target: ErbB
    Summary: EGFR/HER2 inhibitor,potent,selective and reversible
      ≥29.05 mg/mL

Items 541-550 of 810

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Category
  1. Proteases 69item
  2. Apoptosis 47item
  3. Chromatin/Epigenetics 99item
  4. Metabolism 77item
  5. MAPK Signaling 32item
  6. Tyrosine Kinase 97item
  7. DNA Damage/DNA Repair 67item
  8. PI3K/Akt/mTOR Signaling 61item
  9. Microbiology & Virology 39item
  10. Cell Cycle/Checkpoint 68item
  11. Ubiquitination/ Proteasome 27item
  12. JAK/STAT Signaling 36item
  13. TGF-β / Smad Signaling 29item
  14. Angiogenesis 6item
  15. GPCR/G protein 27item
  16. Stem Cell 26item
  17. Membrane Transporter/Ion Channel 30item
  18. Endocrinology and Hormones 17item
  19. Neuroscience 37item
  20. Obesity, Appetite Control & Diabetes 1 item
  21. Other Signal Transduction 3item
  22. Others 69item
  23. Immunology/Inflammation 18item
  24. Cardiovascular 3item
  25. Vitamin D Related 2item
  26. NF-κB 1 item
Specificity
  1. Selective 488item
  2. Non-Selective 3item
Reversibility
  1. Reversible 34item
  2. Irreversible 25item
Target
  1. Caspases 7item
  2. Cyclin-Dependent Kinases 21item
  3. Proteasome 11item
  4. Cathepsins 5item
  5. Histone Deacetylases (HDACs) 26item
  6. Inhibitor of apoptosis proteins (IAP) 1 item
  7. Akt 11item
  8. Bcl-2 8item
  9. PI3K 28item
  10. CXCR 2item
  11. Raf 10item
  12. Aurora Kinases 18item
  13. Bcl-xl 3item
  14. CSF-1R 4item
  15. Glycoproteins 1 item
  16. p97 1 item
  17. Gap Junctions 1 item
  18. MDM2 2item
  19. EZH2 3item
  20. mTOR 16item
  21. Bromodomains 5item
  22. AP-1 3item
  23. MMP 7item
  24. Thymidine Phosphorylases 1 item
  25. Androgen Receptors 3item
  26. Peptidylprolyl isomerases 1 item
  27. Acyl coenzyme A: cholesterol acyltransferases 1 item
  28. Myosin II ATPases 1 item
  29. DT-diaphorases 1 item
  30. Voltage-gated Potassium (KV) Channels 1 item
  31. MER 1 item
  32. FLT3 16item
  33. GSK-3 6item
  34. Factor Xa 4item
  35. LPA Receptors 2item
  36. P-glycoprotein (P-gp) 3item
  37. PLK 9item
  38. Chk 4item
  39. Eph Receptors 2item
  40. VEGFR 28item
  41. PDGFR 19item
  42. c-Kit 9item
  43. RET 2item
  44. IRAK 2item
  45. Bromodomain-containing proteins(BRDs) 1 item
  46. Phosphodiesterases (PDEs) 12item
  47. Mcl-1 5item
  48. Hydrolase 1 item
  49. Thymidylate Synthase 3item
  50. p38 7item
  51. PKB 1 item
  52. JNK 2item
  53. Bcr-Abl 10item
  54. MEK 8item
  55. PORCN 1 item
  56. DOT1L 1 item
  57. FGFR 10item
  58. Nrf2 1 item
  59. Pim 3item
  60. Liver X receptors (LXRs) 1 item
  61. Sir2-like Family Deacetylases (Sirtuins) 1 item
  62. Voltage-gated Sodium (NaV) Channels 1 item
  63. Deubiquitinating enzymes (DUBs) 2item
  64. PP1 1 item
  65. PP2A 1 item
  66. Smoothened 1 item
  67. Neuraminidases (NA) 1 item
  68. MET 5item
  69. Src 14item
  70. Trk Receptors 4item
  71. Aminopeptidases 2item
  72. NMDA Receptors 2item
  73. STAT 6item
  74. Microtubules/Tubulins 1 item
  75. Estrogen and Related Receptors 2item
  76. EGFR 18item
  77. Reverse Transcriptases 5item
  78. ROCK 7item
  79. Hypoxia Inducible Factors (HIFs) 1 item
  80. FAK 3item
  81. JAK 17item
  82. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  83. Syk 4item
  84. Progesterone Receptors 1 item
  85. EZH1 1 item
  86. DNA-PK 6item
  87. HSP90 8item
  88. AMPK 1 item
  89. CCR 1 item
  90. CFTR 2item
  91. Topoisomerases 13item
  92. Cytochrome P450 (CYP450) 8item
  93. Ksp 1 item
  94. Renin 1 item
  95. ErbB 4item
  96. Toll-like receptors (TLRs) 3item
  97. Actin 2item
  98. Serine Proteases 1 item
  99. DNA Methyltransferases 3item
  100. ERK 6item
  101. HMG-CoA Reductases 4item
  102. c-MET 6item
  103. PKC 11item
  104. Calpains 3item
  105. Ca2 /calmodulin-dependent protein kinases (CaMKs) 4item
  106. Protease-Activated Receptors 1 item
  107. Lyn 1 item
  108. RAD51 1 item
  109. HER2 1 item
  110. Pyk2 2item
  111. 5-HT2 Receptors 4item
  112. LRRK2 5item
  113. Voltage-gated Calcium Channels (CaV) 1 item
  114. DGAT 1 item
  115. Insulin and Insulin-like Receptors 4item
  116. PARP 6item
  117. CB1 Receptors 1 item
  118. Pyruvate dehydrogenases (PDH) 1 item
  119. ALK 6item
  120. Sphingosine kinases (SphKs) 2item
  121. Monocarboxylate transporters (MCTs) 1 item
  122. CETP 1 item
  123. PKG 2item
  124. PKA 5item
  125. Myosin light chain kinases (MLCKs) 2item
  126. GPR30 1 item
  127. D1 and D5 Receptors 1 item
  128. D2 Receptors 3item
  129. D3 Receptors 2item
  130. 5-HT1 Receptors 2item
  131. 5-HT7 Receptors 1 item
  132. Lactate Dehydrogenases (LDH) 2item
  133. MK2 2item
  134. Angiotensin-Converting Enzymes (ACEs) 3item
  135. Tie-2 3item
  136. RSK 2item
  137. phosphatases 1 item
  138. Autophagy 3item
  139. ATM/ATR 5item
  140. COX 10item
  141. YAP 1 item
  142. CK1 1 item
  143. CK2 4item
  144. HIPK2 1 item
  145. HIPK3 1 item
  146. HIV Integrases 1 item
  147. Squalene epoxidases 1 item
  148. PRAK 1 item
  149. MAPKAP-K2 1 item
  150. 20S proteasomal chymotrypsin 1 item
  151. Geranylgeranyltransferase I 1 item
  152. Farnesyltransferase 1 item
  153. Nampt 3item
  154. eIF4F 1 item
  155. Cdc42 1 item
  156. SRPK1 1 item
  157. P2X Receptors 2item
  158. Glutaminases 2item
  159. Carbonic Anhydrases 6item
  160. Ron 1 item
  161. G9a 1 item
  162. BLM 1 item
  163. HSV 2item
  164. NADPH Oxidases 3item
  165. Calcium-activated chloride channels (CaCC) 1 item
  166. GPR35 1 item
  167. Aldehyde Dehydrogenases 2item
  168. Synthases/Synthetases 2item
  169. MAGL 1 item
  170. Leukotriene and Related Receptors 1 item
  171. Histamine H1 Receptors 3item
  172. RAR/RXR 1 item
  173. Na /K ATPases 2item
  174. P110 1 item
  175. Hck 2item
  176. Inositol-requiring enzyme 1 (IRE1) 1 item
  177. Na /K /Cl- Symporters (NKCCs) 2item
  178. GABAA Receptors 1 item
  179. Phospholipases 1 item
  180. TRP Channel 2item
  181. RNA Polymerases 2item
  182. DYRK 1 item
  183. Norepinephrine transporter 1 item
  184. 5-HT Transporters 3item
  185. Xanthine oxidoreductases 1 item
  186. Dihydroorotate dehydrogenase 1 item
  187. Guanylyl Cyclases 1 item
  188. Histone Demethylases 1 item
  189. MNK 2item
  190. 5-Lipoxygenases 1 item
  191. NO Donors / Precursors 1 item
  192. CB2 Receptors 1 item
  193. HIV-1 reverse transcriptase 1 item
  194. IL Receptors 2item
  195. CCL2 1 item
  196. Norepinephrine transporters 1 item
  197. 15-lipoxygenases 1 item
  198. Calcium-Activated Potassium (KCa) Channels 2item
  199. AChE 3item
  200. Insulin Receptors 1 item
  201. IRG-1R 1 item
  202. cAMP 1 item
  203. Sulfonylurea receptors 1 item
  204. eEF-2 1 item
  205. Inward Rectifier Potassium (Kir) Channels 2item
  206. CRTH2 1 item
  207. Cdc7 1 item
  208. Nuclear Receptors 1 item
  209. CMV 1 item
  210. ZAP-70 1 item
  211. Catechol O-Methyltransferase (COMT) 2item
  212. fibrinolysis 1 item
  213. Angiotensin AT1 Receptors 3item
  214. D4 Receptors 1 item
  215. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  216. NMDA receptor 1 item
  217. HBV Proteases 1 item
  218. Hydroxylases 2item
  219. Flk-1 1 item
  220. Papains 1 item
  221. Protein Arginine Methyltransferases 1 item
  222. IMPDH 1 item
  223. Na /Ca2 Exchangers (NCXs) 1 item
  224. NAE 2item
  225. Ubiquitin-activating Enzyme E1 2item
  226. SUMOylation 1 item
  227. ATGL 1 item
  228. BACE 2item
  229. Cytidine deaminases 1 item
  230. angiogenesis 1 item
  231. Glucagon Receptors 1 item
  232. 15-PGDH 1 item
  233. DPP-4 5item
  234. PP4 1 item
  235. c-RET 3item
  236. Nonstructural protein 5B (NS5B) 1 item
  237. guanylyl cyclase 1 item
  238. ETA Receptors 2item
  239. ETB Receptors 1 item
  240. p70 rsk 3item
  241. voltage-gated chloride channels 1 item
  242. FPTase 1 item
  243. 5-HT1 Receptor 1 item
  244. Microtubule/Tubulin 1 item
  245. VEGFR3/FLT4 1 item
  246. NTRK1/TRKA 1 item
  247. CSF-1R/c-Fms 1 item
  248. Menin-MLL 2item
  249. Tryptophan hydroxylases (TPH) 2item
  250. ADAMs 1 item
  251. NMPRTase 1 item
  252. Bfl-1 1 item
  253. TAM kinase 1 item
  254. p53-MDM2 interaction 2item
  255. nuclear export 1 item
  256. CRM1 1 item
  257. PTP 1 item
  258. KDR 2item
  259. Fyn kinase 1 item
  260. Abl kinases 1 item
  261. AXL 1 item
  262. Glyoxalase I 1 item
  263. dCTP Pyrophosphatases 1 item
  264. Protein polybromo-1 1 item
  265. SMARCA4 1 item
  266. SMARCA2 1 item
  267. Dipeptidyl-peptidase II 1 item
  268. p53 5item
  269. metalloprotease 1 item
  270. HDAC 2item
  271. Antifungal 1 item
  272. KDM 2item
  273. 5-HT receptors 1 item
  274. sodium channel 2item
  275. c-Fms tyrosine kinase 1 item
  276. PAR 1 item
  277. human lyase 1 item
  278. insulin 1 item
  279. Ub-conjugating enzyme (E2) complex 1 item
  280. Smoothened receptor 1 item
  281. quinone oxidoreductase 1 item
  282. cysteine protease 2item
  283. PPAR 1 item
  284. STK 1 item
  285. USP1/USF1 complex 1 item
  286. IKK 1 item
  287. MSK 1 item
  288. gp120-CD4 interaction 1 item
  289. TRPV 1 item
  290. HCV polymerase 3item
  291. Ftase 1 item
  292. Subtilisin/Kex2p-like proprotein convertase 1 item
  293. PC-PLC 2item
  294. Elastases 1 item
  295. P97 ATPase 1 item
  296. ATP synthase 1 item
  297. NTPDases 1 item
  298. Vitamin D receptors (VDRs) 1 item
  299. Antibiotic 2item
  300. Mer tyrosine kinase 1 item
  301. Hec1 1 item
  302. neprilysin 1 item
  303. GLI 1 item
  304. Stem Cell Differentiation 1 item
  305. PP2A/Nkd interaction 1 item
  306. HMGCR 1 item
  307. AAT 1 item
  308. ErbB-2 1 item
  309. adrenergic receptor 2item
  310. HIV 1 item
  311. 5-HT4 Receptor 1 item
  312. TRPA 1 item
  313. sterol demethylase 1 item
  314. PDK-1 1 item
  315. GAPDH 1 item
  316. telomerase 1 item
  317. Histone Acetyltransferases (HATs) 3item
  318. complex I of the mitochondrial electron transport chain 1 item
  319. F1 Fo-ATPase 1 item
  320. Prk 1 item
  321. potassium channel 1 item
  322. calcium channel 1 item
  323. Ribonucleotide Reductases 1 item
  324. Trx 1 item
  325. Tyrosinases 1 item
  326. Neurokinin receptor 1 item
  327. HSP70 1 item
  328. ICAM 1 item
  329. ITK 1 item
  330. HIF-PH 1 item
  331. NOD1 1 item
  332. NUAK 1 item
  333. Rho 1 item
  334. Aryl hydrocarbon receptors (AHRs) 1 item
  335. Ubiquitin E3 Ligases 1 item
  336. DCLK2 1 item
  337. FAAH 1 item
  338. PTK 1 item
  339. integrase 1 item
  340. L3MBTL 1 item
  341. NOS 2item
  342. MDMX 1 item
  343. TYK2 2item
  344. MUSK 1 item
  345. MAP3K 1 item
  346. GPR3 1 item
  347. Lck 1 item
  348. Adenosine Deaminases 2item
  349. mitochondrial pyruvate carrier (MPC) 1 item
  350. DNA gyrase 1 item
  351. prolactin secretion 1 item
  352. gonadotropin release 1 item
  353. DprE 1 item
  354. Vitamin D 1 item
  355. carnitine reabsorption 1 item
  356. Histamine receptors 1 item
  357. GluR 1 item
  358. 5-HT receptor 1 item
  359. dopamine receptors 1 item
  360. AMPA receptor 1 item
  361. 5-alpha Reductases 1 item
  362. Flk1 2item
  363. SAPK 1 item
  364. p21 1 item
  365. DNA Ligases 1 item
  366. Prostaglandin synthesis 1 item
  367. Protein Tyrosine Phosphatases 1 item
  368. alkaline phosphatases 1 item
  369. ATPases 1 item
  370. glutamate release 1 item
  371. PAFR 1 item
  372. Aromatases 2item
  373. DHFR 1 item
  374. GARFT 1 item
  375. 5-HT 1 item
  376. PHF 1 item
  377. FGR 1 item
  378. YES 2item
  379. Fyn 2item
  380. ARG 1 item
  381. Autotaxin 1 item
  382. UCH 1 item
  383. RHA 1 item
  384. HCV NS3-4A protease 1 item
  385. PKD 1 item
  386. Octamer-binding transcription factor 4 (Oct4) 1 item
  387. Thioredoxin Reductases 1 item
  388. enoyl-acyl-carrier protein reductase 1 item
  389. SHIP 1 item
  390. MCL1 1 item
  391. Bcl-w 1 item
  392. glutathione peroxidase 4 1 item
  393. NADH oxidase 1 item
  394. S-adenosylhomocysteine hydrolase 1 item
  395. Rho-kinase 1 item
  396. tropomyosin receptor kinase 1 item
  397. LSD 1 item
  398. DDX3 1 item
  399. PRMT 1 item
  400. ACE 1 item
  401. GLP 1 item
  402. SK 1 item
  403. MST 1 item
  404. PPK 1 item
  405. c-Syk 1 item
  406. CDK1/CyclinB 1 item
  407. NHE 1 item
  408. IDO 1 item
  409. Tph 1 item
  410. PIM1 kinase 1 item
  411. phospholipase A2 1 item
  412. reverse transcriptase 1 item
  413. epoxide hydrolase 1 item
  414. Serotonin (5-HT) reuptake 1 item
  415. Cholesterol absorption 1 item
  416. Vascular Disrupting Agents (VDA) 1 item
  417. Androgen Receptor 1 item
  418. Substance P/NK1 Receptor 1 item
  419. gp120/CD4 1 item
  420. ATM 1 item
  421. Sirtuin 1 item
  422. NE 1 item
  423. PIKfyve 1 item
  424. Bax 1 item
  425. Glycogen Phosphorylases 1 item
  426. MTH1 1 item
  427. PTEN 1 item
  428. Insulin Receptor 1 item
  429. NS3/4a Proteases 1 item
  430. p90 S6K 1 item
Related Disease
  1. Acne 1 item
  2. Acute Kidney Injury 2item
  3. Acute Lung Injury 1 item
  4. Acute Myelogenous Leukemia 4item
  5. Acute Myeloid Leukemia 19item
  6. Acute Renal Failure 1 item
  7. Adrenocortical Carcinoma 3item
  8. Biliary Cancer 1 item
  9. Bladder Cancer 9item
  10. Bladder Carcinoma 3item
  11. Bladder Diseases 2item
  12. B-lymphoid Malignancies 1 item
  13. Brain Injuries Studies 3item
  14. Breast Cancer 72item
  15. Cancer 349item
  16. Castration-resistant Prostate Cancer 1 item
  17. Cervical Cancer 4item
  18. Cholangiocarcinoma 1 item
  19. Chronic Lymphocytic Leukemia 6item
  20. Chronic Myeloproliferative Disorders 1 item
  21. Clear Cell Renal Cell Carcinoma 1 item
  22. Cocaine-Related Disorders 2item
  23. Colon Cancer 22item
  24. Colon Carcinoma 3item
  25. Colorectal Cancer 28item
  26. Depression 2item
  27. Diabetes 7item
  28. Diffuse Large B-cell Lymphoma 1 item
  29. Dyskinesia 1 item
  30. Dyslipidemia 2item
  31. Epilepsy 3item
  32. Erectile Dysfunction 3item
  33. Friedreich's Ataxia 1 item
  34. Fungi 1 item
  35. Glioblastoma 19item
  36. Glioma 10item
  37. HCV 3item
  38. Heart Failure 5item
  39. Hepatitis C 3item
  40. Hepatocellular Carcinoma 5item
  41. HIV 11item
  42. HIV Infections 11item
  43. Hypercholesterolemia 1 item
  44. Inflammation 1 item
  45. Inflammatory Diseases 7item
  46. Influenza 1 item
  47. Kidney Injury Studies 2item
  48. Leukemia 18item
  49. Liver Cancer 2item
  50. Lung Cancer 19item
  51. Lung Carcinoma 2item
  52. Lymphoma 24item
  53. Mantle Cell Lymphoma 2item
  54. Melanoma 20item
  55. Mixed Lineage Leukemia 1 item
  56. Multiple Myeloma 15item
  57. Myelofibrosis 2item
  58. Myeloma 2item
  59. Neuroblastoma 7item
  60. Neurocognitive Disorders 1 item
  61. Neuronal Protection 1 item
  62. Non-small Cell Lung Cancer 15item
  63. Non-small Cell Lung Carcinoma 1 item
  64. Obsessive-Compulsive Disorder 1 item
  65. Osteoporosis 2item
  66. Ovarian Cancer 21item
  67. Pancreatic Cancer 30item
  68. Pancreatic Carcinoma 1 item
  69. Pentacyclic Triterpenoid 1 item
  70. Prostate Cancer 35item
  71. Psoriasis 3item
  72. Psoriasis Vulgaris 1 item
  73. Pulmonary Fibrosis 2item
  74. Renal Cancer 3item
  75. Renal Cell Carcinoma 4item
  76. Rheumatoid Arthritis 11item
  77. Sarcoma 1 item
  78. Schizophrenia 4item
  79. Sleep Disorders 1 item
  80. Soft Tissue Sarcoma 1 item
  81. Squamous Cell Carcinoma 2item
  82. Thyroid Cancer 4item
  83. Tuberculosis 3item
  84. Type 2 Diabetes 10item