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  • Search results for: 'btk inhibitor 1'

Search results for: 'btk inhibitor 1'

Items 141-150 of 343

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  1. Roflumilast
    A4319 Roflumilast
    Summary: PDE-4 inhibitor
      insoluble in H2O; ≥20.2 mg/mL
  2. XL-888
    A4388 XL-888
     1 Citation
    Target: HSP90
    Summary: Hsp90 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥18.2 mg/mL
  3. AGI-6780
    A3146 AGI-6780
    Target: IDH2
    Summary: IDH2/R140Q mutation inhibitor
      ≥22.25 mg/mL
  4. Cobicistat (GS-9350)
    A4313 Cobicistat (GS-9350)
    Target: Cytochrome P450 (CYP450)
    Summary: Selective CYP3A inhibitor
      insoluble in H2O; ≥150.9 mg/mL
  5. Deltarasin
    A3358 Deltarasin
    Target: Phosphodiesterases (PDEs)
    Summary: KRAS-PDEδ interaction inhibitor
      Soluble in DMSO
  6. DMP 777
    A3369 DMP 777
    Summary: Leukocyte elastase (HLE) inhibitor
      Soluble in DMSO
  7. GSK180
    A8723 GSK180
    Target: Kynurenine-3-monooxygenase
    Summary: inhibitor of kynurenine-3-monooxygenase (KMO)
      ≥27.6 mg/mL
  8. Apremilast (CC-10004)
    A4317 Apremilast (CC-10004)
    Target: Phosphodiesterases (PDEs)
    Summary: PDE4 inhibitor
      ≥23.05 mg/mL
  9. Pitavastatin Calcium
    A8504 Pitavastatin Calcium
     1 Citation
    Target: HMG-CoA Reductases
    Summary: Enzyme HMGCR inhibitor
      ≥34.85 mg/mL
  10. Varespladib (LY315920)
    A4356 Varespladib (LY315920)
    Target: Phospholipases
    Summary: HnsPLA inhibitor,potent and selective

Items 141-150 of 343

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  1. PPAR 8item
  2. 5-alpha Reductase 3item
  3. 5-Lipoxygenase 9item
  4. Adenosine Deaminase 3item
  5. Aminopeptidase 1 item
  6. C14ɑ demethylase 2item
  7. Carbonic Anhydrase 7item
  8. CETP 4item
  9. Cholesterol absorption 1 item
  10. CPT1 2item
  11. CYP3A/CYP450 12item
  12. Dehydrogenase 33item
  13. DHFR 5item
  14. DGAT 6item
  15. Dopamine β-hydroxylase 5item
  16. Enolase 1 item
  17. FAAH 19item
  18. Factor Xa 3item
  19. Ferroptosis 3item
  20. Folate Analogue 1 item
  21. HLE 1 item
  22. HMG-CoA Reductase 13item
  23. HSP 23item
  24. IDO 7item
  25. KRAS-PDEδ 2item
  26. Lipid Metabolism 8item
  27. MAO 6item
  28. Neuronal Metabolism 2item
  29. Oxidative Phosphorylation 1 item
  30. P450 13item
  31. PDE 52item
  32. Phospholipase 28item
  33. Procollagen C Proteinase 1 item
  34. SCD 3item
  35. SGLT 7item
  36. TPH 4item
  37. Transferase 20item
  38. Transaminase 1 item
  39. monooxygenase 1 item
  40. aldehyde dehydrogenase 1 item
  41. Squalene synthase 1 item
  42. Hydrolase 9item
  43. ornithine decarboxylase 1 item
  44. Amino acid metabolism 1 item
  45. phosphatases 5item
  46. MGL 1 item
  47. Galactosidase 1 item
  48. 12-Lipoxygenase 1 item
  49. Lipase inhibitor 1 item
Specificity
  1. Selective 63item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 1 item
  2. Irreversible 3item
Target
  1. Acyl coenzyme A: cholesterol acyltransferases 1 item
  2. Factor Xa 1 item
  3. Phosphodiesterases (PDEs) 16item
  4. Thymidylate Synthase 1 item
  5. 3-phosphoglycerate dehydrogenase 1 item
  6. Kynurenine-3-monooxygenase 1 item
  7. Aminopeptidases 1 item
  8. Stearoyl-CoA 9-desaturase (SCD-1) 2item
  9. HSP90 9item
  10. Cytochrome P450 (CYP450) 6item
  11. Ferroptosis 1 item
  12. HMG-CoA Reductases 6item
  13. SGLT 1 item
  14. DGAT 2item
  15. Pyruvate dehydrogenases (PDH) 1 item
  16. CETP 2item
  17. Lactate Dehydrogenases (LDH) 3item
  18. Fatty-acid-binding proteins (FABPs) 1 item
  19. IDH2 1 item
  20. Nampt 1 item
  21. Carbonic Anhydrases 3item
  22. Aldehyde Dehydrogenases 2item
  23. Phospholipases 1 item
  24. Catechol O-Methyltransferase (COMT) 1 item
  25. Hydroxylases 1 item
  26. FPTase 1 item
  27. Tryptophan hydroxylases (TPH) 2item
  28. sodium channel 1 item
  29. PPAR 1 item
  30. Ftase 1 item
  31. PC-PLC 1 item
  32. HMGCR 1 item
  33. adrenergic receptor 1 item
  34. sterol demethylase 1 item
  35. GAPDH 1 item
  36. complex I of the mitochondrial electron transport chain 1 item
  37. potassium channel 1 item
  38. calcium channel 1 item
  39. FAAH 1 item
  40. carnitine reabsorption 1 item
  41. 5-alpha Reductases 1 item
  42. DHFR 1 item
  43. GARFT 1 item
  44. glutathione peroxidase 4 1 item
  45. S-adenosylhomocysteine hydrolase 1 item
  46. IDO 1 item
  47. Tph 1 item
  48. epoxide hydrolase 1 item
  49. Cholesterol absorption 1 item
  50. Glycogen Phosphorylases 1 item
Reported Experiments
  1. Animal Experiments 93item
  2. Cell Experiments 77item
Related Disease
  1. Acne 1 item
  2. Acute Kidney Injury 1 item
  3. Acute Myelogenous Leukemia 1 item
  4. Acute Myeloid Leukemia 2item
  5. Bladder Cancer 1 item
  6. Bladder Carcinoma 1 item
  7. Brain Injuries Studies 1 item
  8. Breast Cancer 8item
  9. Cancer 32item
  10. Chronic Lymphocytic Leukemia 1 item
  11. Cocaine-Related Disorders 2item
  12. Colon Cancer 1 item
  13. Diabetes 2item
  14. Dyslipidemia 1 item
  15. Epilepsy 2item
  16. Erectile Dysfunction 4item
  17. Fungi 1 item
  18. Glioblastoma 1 item
  19. Glioma 1 item
  20. Hepatic Cancer 1 item
  21. HIV Infections 1 item
  22. Hypercholesterolemia 3item
  23. Inflammation 1 item
  24. Inflammatory Diseases 1 item
  25. Kidney Injury Studies 1 item
  26. Leukemia 1 item
  27. Lung Cancer 3item
  28. Lymphoma 1 item
  29. Melanoma 7item
  30. Multiple Myeloma 2item
  31. Neuroblastoma 2item
  32. Neurocognitive Disorders 1 item
  33. Non-small Cell Lung Cancer 2item
  34. Obsessive-Compulsive Disorder 1 item
  35. Osteoporosis 1 item
  36. Pancreatic Cancer 2item
  37. Pancreatic Carcinoma 1 item
  38. Prostate Cancer 7item
  39. Psoriasis 2item
  40. Psoriasis Vulgaris 1 item
  41. Pulmonary Arterial Hypertension 1 item
  42. Rheumatoid Arthritis 1 item
  43. Schizophrenia 2item
  44. Type 2 Diabetes 2item