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Search results for: 'btk inhibitor 1'

Items 101-110 of 855

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  1. AZD5363
    A1387 AZD5363
     3 Citation
    Target: Akt
    Summary: AKT inhibitor,pyrrolopyrimidine derived
      ≥21.45 mg/mL
  2. Dorzolamide
    B1279 Dorzolamide
    Target: Carbonic Anhydrases
    Summary: Carbonic anhydrase inhibitor
      Soluble in DMSO
  3. LX-1031
    A3565 LX-1031
    Target: Tryptophan hydroxylases (TPH)
    Summary: TPH inhibitor
      ≥26.93 mg/mL
  4. Ezetimibe
    A8430 Ezetimibe
    Target: Cholesterol absorption
    Summary: Cholesterol transport inhibitor
      ≥20.45 mg/mL
  5. PYZD-4409
    B1244 PYZD-4409
    Target: Ubiquitin-activating Enzyme E1
    Summary: E1 enzyme inhibitor
      Soluble in DMSO
  6. Torin 2
    B1640 Torin 2
     1 Citation
    Target: mTOR|DNA-PK|ATM/ATR
    Summary: MTOR inhibitor,highly potent and selective
      ≥21.6 mg/mL
  7. Avasimibe
    A4318 Avasimibe
    Target: Acyl coenzyme A: cholesterol acyltransferases
    Summary: ACAT inhibitor,orally bioavailable
      ≥25.09 mg/mL
  8. SKI II
    B2226 SKI II
    Target: Sphingosine kinases (SphKs)
    Summary: Sphingosine kinase(SK) inhibitor
      insoluble in H2O; insoluble in EtOH; ≥15.15 mg/mL
  9. RO4929097
    A4005 RO4929097
     1 Citation
    Summary: γ secretase inhibitor
      ≥23.47 mg/mL
  10. Anastrozole
    B1382 Anastrozole
    Target: Aromatases
    Summary: Aromatase inhibitor
      insoluble in H2O; ≥14.15 mg/mL

Items 101-110 of 855

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  1. Signaling Pathways 810item
  2. Natural Products 11item
  3. Protein 2item
  4. Peptides 1 item
  5. Probes & Dyes 1 item
  6. Peptides & Proteins 4item
  7. Lab Reagents 10item
Specificity
  1. Selective 509item
  2. Non-Selective 4item
Reversibility
  1. Reversible 34item
  2. Irreversible 25item
Target
  1. Caspases 7item
  2. Cyclin-Dependent Kinases 21item
  3. Proteasome 11item
  4. Cathepsins 5item
  5. Histone Deacetylases (HDACs) 27item
  6. Inhibitor of apoptosis proteins (IAP) 1 item
  7. Akt 11item
  8. Bcl-2 8item
  9. PI3K 28item
  10. CXCR 2item
  11. Raf 10item
  12. Aurora Kinases 18item
  13. Bcl-xl 3item
  14. CSF-1R 4item
  15. Glycoproteins 1 item
  16. p97 1 item
  17. Gap Junctions 1 item
  18. MDM2 2item
  19. EZH2 3item
  20. mTOR 16item
  21. Bromodomains 5item
  22. AP-1 3item
  23. MMP 7item
  24. Thymidine Phosphorylases 1 item
  25. Androgen Receptors 3item
  26. Peptidylprolyl isomerases 1 item
  27. Acyl coenzyme A: cholesterol acyltransferases 1 item
  28. Myosin II ATPases 1 item
  29. DT-diaphorases 1 item
  30. Voltage-gated Potassium (KV) Channels 1 item
  31. MER 1 item
  32. FLT3 16item
  33. GSK-3 6item
  34. Factor Xa 4item
  35. LPA Receptors 2item
  36. P-glycoprotein (P-gp) 3item
  37. PLK 9item
  38. Chk 4item
  39. Eph Receptors 2item
  40. VEGFR 28item
  41. PDGFR 19item
  42. c-Kit 9item
  43. RET 2item
  44. IRAK 2item
  45. Bromodomain-containing proteins(BRDs) 1 item
  46. Phosphodiesterases (PDEs) 12item
  47. Mcl-1 5item
  48. Hydrolase 1 item
  49. Thymidylate Synthase 3item
  50. p38 7item
  51. PKB 1 item
  52. JNK 2item
  53. Bcr-Abl 10item
  54. MEK 8item
  55. PORCN 1 item
  56. DOT1L 1 item
  57. FGFR 10item
  58. Nrf2 1 item
  59. Pim 4item
  60. Liver X receptors (LXRs) 1 item
  61. Sir2-like Family Deacetylases (Sirtuins) 1 item
  62. Voltage-gated Sodium (NaV) Channels 1 item
  63. Deubiquitinating enzymes (DUBs) 2item
  64. PP1 1 item
  65. PP2A 1 item
  66. Smoothened 1 item
  67. Neuraminidases (NA) 1 item
  68. MET 5item
  69. Src 14item
  70. Trk Receptors 4item
  71. Aminopeptidases 2item
  72. NMDA Receptors 2item
  73. STAT 8item
  74. Microtubules/Tubulins 1 item
  75. Estrogen and Related Receptors 2item
  76. EGFR 19item
  77. Reverse Transcriptases 6item
  78. ROCK 7item
  79. Hypoxia Inducible Factors (HIFs) 1 item
  80. FAK 4item
  81. JAK 17item
  82. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  83. Syk 4item
  84. Progesterone Receptors 1 item
  85. EZH1 1 item
  86. DNA-PK 6item
  87. HSP90 8item
  88. AMPK 1 item
  89. CCR 1 item
  90. Angiotensin AT2 Receptors 1 item
  91. CFTR 2item
  92. Topoisomerases 15item
  93. Cytochrome P450 (CYP450) 8item
  94. Ksp 1 item
  95. Renin 1 item
  96. ErbB 4item
  97. Toll-like receptors (TLRs) 3item
  98. Actin 2item
  99. Serine Proteases 1 item
  100. DNA Methyltransferases 3item
  101. ERK 7item
  102. HMG-CoA Reductases 4item
  103. c-MET 6item
  104. PKC 11item
  105. Calpains 3item
  106. Ca2 /calmodulin-dependent protein kinases (CaMKs) 4item
  107. Protease-Activated Receptors 1 item
  108. Lyn 1 item
  109. RAD51 1 item
  110. HER2 1 item
  111. Pyk2 2item
  112. USP 1 item
  113. 5-HT2 Receptors 4item
  114. LRRK2 5item
  115. Voltage-gated Calcium Channels (CaV) 2item
  116. DGAT 1 item
  117. Insulin and Insulin-like Receptors 4item
  118. PARP 7item
  119. CB1 Receptors 2item
  120. Pyruvate dehydrogenases (PDH) 1 item
  121. ALK 7item
  122. Sphingosine kinases (SphKs) 2item
  123. Monocarboxylate transporters (MCTs) 1 item
  124. CETP 1 item
  125. PKG 2item
  126. PKA 5item
  127. Myosin light chain kinases (MLCKs) 2item
  128. GPR30 1 item
  129. D1 and D5 Receptors 1 item
  130. D2 Receptors 3item
  131. D3 Receptors 2item
  132. 5-HT1 Receptors 2item
  133. 5-HT7 Receptors 1 item
  134. Lactate Dehydrogenases (LDH) 2item
  135. MK2 2item
  136. Angiotensin-Converting Enzymes (ACEs) 5item
  137. Tie-2 3item
  138. RSK 2item
  139. phosphatases 2item
  140. Autophagy 3item
  141. ATM/ATR 5item
  142. COX 11item
  143. YAP 1 item
  144. CK1 1 item
  145. CK2 4item
  146. HIPK2 1 item
  147. HIPK3 1 item
  148. HIV Integrases 2item
  149. Pregnane X Receptors 1 item
  150. Squalene epoxidases 1 item
  151. PRAK 1 item
  152. MAPKAP-K2 1 item
  153. GpIIb/IIIa receptor 1 item
  154. Guanine nucleotide exchange factors (GEFs) 1 item
  155. 20S proteasomal chymotrypsin 1 item
  156. Geranylgeranyltransferase I 1 item
  157. Farnesyltransferase 1 item
  158. Nampt 3item
  159. eIF4F 1 item
  160. Cdc42 1 item
  161. SRPK1 1 item
  162. P2X Receptors 2item
  163. Glutaminases 2item
  164. Carbonic Anhydrases 7item
  165. Ron 1 item
  166. G9a 1 item
  167. BLM 1 item
  168. HSV 2item
  169. NADPH Oxidases 3item
  170. Calcium-activated chloride channels (CaCC) 1 item
  171. GPR35 1 item
  172. Aldehyde Dehydrogenases 2item
  173. Synthases/Synthetases 2item
  174. MAGL 2item
  175. Leukotriene and Related Receptors 1 item
  176. Histamine H1 Receptors 4item
  177. RAR/RXR 1 item
  178. Na /K ATPases 3item
  179. P110 1 item
  180. Hck 2item
  181. Inositol-requiring enzyme 1 (IRE1) 3item
  182. Na /K /Cl- Symporters (NKCCs) 2item
  183. GABAA Receptors 1 item
  184. Phospholipases 1 item
  185. Monoamine oxidases (MAOs) 1 item
  186. Organic anion transporters (OATs) 1 item
  187. TRP Channel 3item
  188. RNA Polymerases 3item
  189. DYRK 1 item
  190. Norepinephrine transporter 1 item
  191. 5-HT Transporters 3item
  192. Xanthine oxidoreductases 1 item
  193. Dihydroorotate dehydrogenase 1 item
  194. Guanylyl Cyclases 1 item
  195. Histone Demethylases 2item
  196. MNK 2item
  197. 5-Lipoxygenases 1 item
  198. NO Donors / Precursors 2item
  199. CB2 Receptors 2item
  200. HIV-1 reverse transcriptase 1 item
  201. IL Receptors 2item
  202. CCL2 1 item
  203. Noradrenaline reuptake 1 item
  204. Norepinephrine transporters 1 item
  205. 15-lipoxygenases 1 item
  206. Calcium-Activated Potassium (KCa) Channels 2item
  207. AChE 3item
  208. Insulin Receptors 1 item
  209. IRG-1R 1 item
  210. cAMP 1 item
  211. Sulfonylurea receptors 1 item
  212. Cdc2-like kinase (Clk) 1 item
  213. eEF-2 1 item
  214. Inward Rectifier Potassium (Kir) Channels 3item
  215. CRTH2 1 item
  216. Cdc7 1 item
  217. Nuclear Receptors 1 item
  218. CMV 1 item
  219. ZAP-70 1 item
  220. Catechol O-Methyltransferase (COMT) 2item
  221. fibrinolysis 1 item
  222. Angiotensin AT1 Receptors 3item
  223. D4 Receptors 1 item
  224. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  225. NMDA receptor 1 item
  226. HBV Proteases 1 item
  227. Hydroxylases 2item
  228. Flk-1 1 item
  229. Papains 1 item
  230. Protein Arginine Methyltransferases 1 item
  231. IMPDH 1 item
  232. Na /Ca2 Exchangers (NCXs) 1 item
  233. NAE 2item
  234. Ubiquitin-activating Enzyme E1 2item
  235. SUMOylation 1 item
  236. ATGL 1 item
  237. BACE 2item
  238. Cytidine deaminases 1 item
  239. angiogenesis 1 item
  240. Glucagon Receptors 1 item
  241. 15-PGDH 1 item
  242. DPP-4 5item
  243. PP4 1 item
  244. c-RET 3item
  245. Nonstructural protein 5B (NS5B) 1 item
  246. guanylyl cyclase 1 item
  247. ETA Receptors 2item
  248. ETB Receptors 1 item
  249. p70 rsk 3item
  250. voltage-gated chloride channels 1 item
  251. FPTase 1 item
  252. 5-HT1 Receptor 1 item
  253. Microtubule/Tubulin 1 item
  254. VEGFR3/FLT4 1 item
  255. NTRK1/TRKA 1 item
  256. CSF-1R/c-Fms 1 item
  257. Menin-MLL 2item
  258. Tryptophan hydroxylases (TPH) 2item
  259. ADAMs 1 item
  260. NMPRTase 1 item
  261. Bfl-1 1 item
  262. TAM kinase 1 item
  263. p53-MDM2 interaction 2item
  264. nuclear export 1 item
  265. CRM1 1 item
  266. PTP 1 item
  267. KDR 2item
  268. Fyn kinase 1 item
  269. Abl kinases 1 item
  270. Trypsin-like protease 1 item
  271. AXL 1 item
  272. Glyoxalase I 1 item
  273. dCTP Pyrophosphatases 1 item
  274. Protein polybromo-1 1 item
  275. SMARCA4 1 item
  276. SMARCA2 1 item
  277. ERAD 1 item
  278. Dipeptidyl-peptidase II 1 item
  279. p53 5item
  280. metalloprotease 1 item
  281. HDAC 2item
  282. Antifungal 1 item
  283. KDM 2item
  284. 5-HT receptors 1 item
  285. sodium channel 3item
  286. c-Fms tyrosine kinase 1 item
  287. PAR 1 item
  288. human lyase 1 item
  289. insulin 1 item
  290. Ub-conjugating enzyme (E2) complex 1 item
  291. Smoothened receptor 1 item
  292. quinone oxidoreductase 1 item
  293. cysteine protease 2item
  294. PPAR 1 item
  295. STK 1 item
  296. USP1/USF1 complex 1 item
  297. IKK 1 item
  298. MSK 1 item
  299. gp120-CD4 interaction 1 item
  300. TRPV 1 item
  301. HCV polymerase 3item
  302. Ftase 1 item
  303. Subtilisin/Kex2p-like proprotein convertase 1 item
  304. PC-PLC 2item
  305. Elastases 1 item
  306. P97 ATPase 1 item
  307. ATP synthase 1 item
  308. Glucosidases 1 item
  309. NTPDases 1 item
  310. Vitamin D receptors (VDRs) 1 item
  311. Antibiotic 3item
  312. Mer tyrosine kinase 1 item
  313. Hec1 1 item
  314. neprilysin 1 item
  315. GLI 1 item
  316. decarboxylase 1 item
  317. Stem Cell Differentiation 1 item
  318. PP2A/Nkd interaction 1 item
  319. HMGCR 1 item
  320. AAT 1 item
  321. ErbB-2 1 item
  322. adrenergic receptor 2item
  323. HIV 1 item
  324. 5-HT4 Receptor 1 item
  325. TRPA 1 item
  326. sterol demethylase 1 item
  327. PDK-1 1 item
  328. GAPDH 1 item
  329. telomerase 1 item
  330. Histone Acetyltransferases (HATs) 3item
  331. complex I of the mitochondrial electron transport chain 1 item
  332. F1 Fo-ATPase 1 item
  333. Prk 1 item
  334. potassium channel 1 item
  335. calcium channel 1 item
  336. Ribonucleotide Reductases 1 item
  337. Trx 1 item
  338. Tyrosinases 1 item
  339. Neurokinin receptor 1 item
  340. HSP70 1 item
  341. ICAM 1 item
  342. ITK 1 item
  343. HIF-PH 1 item
  344. NOD1 1 item
  345. troponin 1 item
  346. NUAK 1 item
  347. Rho 1 item
  348. Aryl hydrocarbon receptors (AHRs) 1 item
  349. Ubiquitin E3 Ligases 1 item
  350. DCLK2 1 item
  351. FAAH 1 item
  352. PTK 1 item
  353. integrase 1 item
  354. L3MBTL 1 item
  355. NOS 2item
  356. MDMX 1 item
  357. TYK2 2item
  358. MUSK 1 item
  359. MAP3K 1 item
  360. GPR3 1 item
  361. Lck 1 item
  362. Adenosine Deaminases 2item
  363. mitochondrial pyruvate carrier (MPC) 1 item
  364. DNA gyrase 1 item
  365. prolactin secretion 1 item
  366. gonadotropin release 1 item
  367. DprE 1 item
  368. Vitamin D 1 item
  369. carnitine reabsorption 1 item
  370. Histamine receptors 1 item
  371. GluR 1 item
  372. 5-HT receptor 1 item
  373. dopamine receptors 1 item
  374. AMPA receptor 1 item
  375. 5-alpha Reductases 1 item
  376. Flk1 2item
  377. SAPK 1 item
  378. p21 1 item
  379. DNA Ligases 1 item
  380. Prostaglandin synthesis 1 item
  381. Protein Tyrosine Phosphatases 1 item
  382. alkaline phosphatases 1 item
  383. ATPases 1 item
  384. glutamate release 1 item
  385. PAFR 1 item
  386. Aromatases 2item
  387. DHFR 1 item
  388. GARFT 1 item
  389. 5-HT 1 item
  390. PHF 1 item
  391. FGR 1 item
  392. YES 2item
  393. Fyn 2item
  394. ARG 1 item
  395. Autotaxin 1 item
  396. UCH 1 item
  397. RHA 1 item
  398. HCV NS3-4A protease 1 item
  399. PKD 1 item
  400. Octamer-binding transcription factor 4 (Oct4) 1 item
  401. Pyruvate kinases 1 item
  402. Thioredoxin Reductases 1 item
  403. enoyl-acyl-carrier protein reductase 1 item
  404. SHIP 1 item
  405. MCL1 1 item
  406. Bcl-w 1 item
  407. glutathione peroxidase 4 1 item
  408. NADH oxidase 1 item
  409. S-adenosylhomocysteine hydrolase 1 item
  410. Rho-kinase 1 item
  411. tropomyosin receptor kinase 1 item
  412. LSD 1 item
  413. DDX3 1 item
  414. PRMT 1 item
  415. ACE 1 item
  416. GLP 1 item
  417. SK 1 item
  418. MST 1 item
  419. PPK 1 item
  420. c-Syk 1 item
  421. CDK1/CyclinB 1 item
  422. NHE 1 item
  423. IDO 2item
  424. Tph 1 item
  425. PIM1 kinase 1 item
  426. phospholipase A2 1 item
  427. reverse transcriptase 1 item
  428. epoxide hydrolase 1 item
  429. Serotonin (5-HT) reuptake 1 item
  430. Cholesterol absorption 1 item
  431. Vascular Disrupting Agents (VDA) 1 item
  432. Androgen Receptor 1 item
  433. Substance P/NK1 Receptor 1 item
  434. gp120/CD4 1 item
  435. ATM 1 item
  436. Sirtuin 1 item
  437. NE 1 item
  438. PIKfyve 1 item
  439. Bax 1 item
  440. Glycogen Phosphorylases 1 item
  441. MTH1 1 item
  442. PTEN 1 item
  443. Insulin Receptor 1 item
  444. NS3/4a Proteases 1 item
  445. p90 S6K 1 item
Related Disease
  1. Acne 1 item
  2. Acute Kidney Injury 3item
  3. Acute Lung Injury 1 item
  4. Acute Myelogenous Leukemia 4item
  5. Acute Myeloid Leukemia 19item
  6. Acute Renal Failure 1 item
  7. Adrenocortical Carcinoma 3item
  8. Biliary Cancer 1 item
  9. Bladder Cancer 9item
  10. Bladder Carcinoma 3item
  11. Bladder Diseases 2item
  12. B-lymphoid Malignancies 1 item
  13. Brain Injuries Studies 3item
  14. Breast Cancer 75item
  15. Cancer 360item
  16. Castration-resistant Prostate Cancer 1 item
  17. Cervical Cancer 4item
  18. Cholangiocarcinoma 1 item
  19. Chronic Lymphocytic Leukemia 6item
  20. Chronic Myeloproliferative Disorders 1 item
  21. Clear Cell Renal Cell Carcinoma 1 item
  22. Cocaine-Related Disorders 2item
  23. Colon Cancer 23item
  24. Colon Carcinoma 3item
  25. Colorectal Cancer 28item
  26. Depression 2item
  27. Diabetes 7item
  28. Diffuse Large B-cell Lymphoma 1 item
  29. Dyskinesia 1 item
  30. Dyslipidemia 2item
  31. Epilepsy 3item
  32. Erectile Dysfunction 3item
  33. Friedreich's Ataxia 2item
  34. Fungi 1 item
  35. Glioblastoma 19item
  36. Glioma 10item
  37. HCV 3item
  38. Heart Failure 6item
  39. Hepatitis C 3item
  40. Hepatocellular Carcinoma 5item
  41. HIV 11item
  42. HIV Infections 11item
  43. Hypercholesterolemia 1 item
  44. Inflammation 1 item
  45. Inflammatory Diseases 7item
  46. Influenza 1 item
  47. Kidney Injury Studies 3item
  48. Leukemia 19item
  49. Liver Cancer 2item
  50. Lung Cancer 21item
  51. Lung Carcinoma 2item
  52. Lymphoma 26item
  53. Mantle Cell Lymphoma 2item
  54. Melanoma 20item
  55. Mixed Lineage Leukemia 1 item
  56. Multiple Myeloma 15item
  57. Myelofibrosis 2item
  58. Myeloma 2item
  59. Neuroblastoma 7item
  60. Neurocognitive Disorders 1 item
  61. Neuronal Protection 1 item
  62. Non-small Cell Lung Cancer 15item
  63. Non-small Cell Lung Carcinoma 1 item
  64. Obsessive-Compulsive Disorder 1 item
  65. Osteoporosis 2item
  66. Ovarian Cancer 22item
  67. Pancreatic Cancer 31item
  68. Pancreatic Carcinoma 1 item
  69. Pentacyclic Triterpenoid 1 item
  70. Prostate Cancer 37item
  71. Psoriasis 3item
  72. Psoriasis Vulgaris 1 item
  73. Pulmonary Fibrosis 2item
  74. Renal Cancer 3item
  75. Renal Cell Carcinoma 4item
  76. Rheumatoid Arthritis 11item
  77. Sarcoma 1 item
  78. Schizophrenia 5item
  79. Sleep Disorders 2item
  80. Soft Tissue Sarcoma 1 item
  81. Squamous Cell Carcinoma 2item
  82. Thyroid Cancer 4item
  83. Tuberculosis 3item
  84. Type 2 Diabetes 11item