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Search results for: 'btk inhibitor 1'

Items 431-440 of 1057

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  1. AHU-377(Sacubitril)
    B1070 AHU-377(Sacubitril)
    Target: neprilysin
    Summary: Neprilysin inhibitor
      ≥41.1 mg/mL
  2. BLU9931
    A8706 BLU9931
    Target: FGFR
    Summary: FGFR4 inhibitor,potent and irreversible
      ≥50.9 mg/mL
  3. Elacridar
    A3384 Elacridar
    Target: P-glycoprotein (P-gp)
    Summary: BCRP inhibitor
      ≥56.4 mg/mL
  4. UNC2250
    B2060 UNC2250
    Summary: Mer inhibitor,potent and selective
      ≥22.05 mg/mL
  5. IWP-L6
    B2305 IWP-L6
    Summary: Porcupine inhibitor,highy potent
      ≥22.45 mg/mL
  6. Semagacestat (LY450139)
    A8190 Semagacestat (LY450139)
    Summary: γ-secretase inhibitor
      insoluble in H2O; ≥18.05 mg/mL
  7. 3-Deazaneplanocin A (DZNep) hydrochloride
    A8182 3-Deazaneplanocin A (DZNep) hydrochloride
     1 Citation
    Target: EZH2
    Summary: SAHH and EZH2 inhibitor
      insoluble in EtOH; ≥14.94 mg/mL
  8. CP-91149
    A8403 CP-91149
    Target: Glycogen Phosphorylases
    Summary: Selective inhibitor of glycogen phosphorylase
      insoluble in H2O; ≥16.4 mg/mL
  9. TG 100801
    A3870 TG 100801
    Target: VEGFR|FGFR|Src|Fyn kinase
    Summary: Multi-kinase inhibitor
      Soluble in DMSO
  10. IPA-3
    B2169 IPA-3
     1 Citation
    Target: PAK
    Summary: Non-ATP competitive Pak1 inhibitor
      insoluble in H2O; ≥16.1 mg/mL

Items 431-440 of 1057

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  1. Signaling Pathways 1009item
  2. Natural Products 12item
  3. Other Products 1 item
  4. Peptides 1 item
  5. Probes & Dyes 2item
  6. Peptides & Proteins 1 item
  7. Lab Reagents 11item
Specificity
  1. Selective 741item
  2. Non-Selective 6item
Reversibility
  1. Reversible 55item
  2. Irreversible 31item
Target
  1. Caspases 9item
  2. Cyclin-Dependent Kinases 25item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 12item
  5. Cathepsins 9item
  6. Histone Deacetylases (HDACs) 33item
  7. Inhibitor of apoptosis proteins (IAP) 3item
  8. Akt 13item
  9. Bcl-2 9item
  10. PI3K 36item
  11. CXCR 4item
  12. Raf 13item
  13. Aurora Kinases 20item
  14. Bcl-xl 2item
  15. CSF-1R 4item
  16. Glycoproteins 1 item
  17. p97 1 item
  18. Gap Junctions 1 item
  19. MDM2 2item
  20. EZH2 4item
  21. mTOR 20item
  22. Bromodomains 6item
  23. AP-1 3item
  24. MMP 8item
  25. Thymidine Phosphorylases 1 item
  26. Androgen Receptors 5item
  27. Peptidylprolyl isomerases 1 item
  28. Acyl coenzyme A: cholesterol acyltransferases 1 item
  29. Myosin II ATPases 1 item
  30. DT-diaphorases 1 item
  31. Voltage-gated Potassium (KV) Channels 1 item
  32. MER 1 item
  33. FLT3 19item
  34. GSK-3 10item
  35. Factor Xa 4item
  36. LPA Receptors 3item
  37. P-glycoprotein (P-gp) 5item
  38. PLK 10item
  39. Chk 7item
  40. Eph Receptors 2item
  41. VEGFR 40item
  42. PDGFR 25item
  43. c-Kit 13item
  44. RET 4item
  45. IRAK 1 item
  46. Bromodomain-containing proteins(BRDs) 1 item
  47. Phosphodiesterases (PDEs) 16item
  48. Mcl-1 6item
  49. Hydrolase 1 item
  50. Thymidylate Synthase 3item
  51. p38 10item
  52. PKB 1 item
  53. JNK 4item
  54. SGK 1 item
  55. Bcr-Abl 13item
  56. Kynurenine-3-monooxygenase 1 item
  57. MEK 13item
  58. PORCN 1 item
  59. DOT1L 3item
  60. FGFR 17item
  61. Nrf2 2item
  62. Insulin-like growth factor receptors(IGFRs) 1 item
  63. CGRP receptors 1 item
  64. Pim 4item
  65. Liver X receptors (LXRs) 1 item
  66. Glucagon-like peptide 1 (GLP-1) receptors 2item
  67. Sir2-like Family Deacetylases (Sirtuins) 3item
  68. Voltage-gated Sodium (NaV) Channels 1 item
  69. Deubiquitinating enzymes (DUBs) 3item
  70. PP1 1 item
  71. PP2A 1 item
  72. Smoothened 4item
  73. Eukaryotic elongation factors 1 item
  74. Neuraminidases (NA) 2item
  75. MET 7item
  76. Src 14item
  77. Trk Receptors 6item
  78. Integrins 1 item
  79. Aminopeptidases 4item
  80. NMDA Receptors 2item
  81. STAT 10item
  82. ATP Citrate Lyases 1 item
  83. Microtubules/Tubulins 6item
  84. Estrogen and Related Receptors 2item
  85. EGFR 23item
  86. Hedgehog 1 item
  87. Reverse Transcriptases 6item
  88. ROCK 9item
  89. BTK 1 item
  90. RIP kinases 1 item
  91. Monocyte chemotactic proteins 1 item
  92. PAK 3item
  93. Hypoxia Inducible Factors (HIFs) 2item
  94. Tankyrases 1 item
  95. Inositol Phosphatases 1 item
  96. FAK 7item
  97. BMP and Other Activin Receptors 3item
  98. JAK 20item
  99. p300 1 item
  100. Stearoyl-CoA 9-desaturase (SCD-1) 2item
  101. Syk 7item
  102. Progesterone Receptors 1 item
  103. EZH1 2item
  104. DNA-PK 7item
  105. HSP90 12item
  106. AMPK 2item
  107. Gutathione S-transferase 1 item
  108. CCR 2item
  109. PDHK 1 item
  110. Angiotensin AT2 Receptors 2item
  111. Notch 1 item
  112. S-nitrosoglutathione reductase 1 item
  113. CFTR 2item
  114. TNKS 1 item
  115. Topoisomerases 16item
  116. Cytochrome P450 (CYP450) 10item
  117. thrombin 1 item
  118. Ksp 2item
  119. Renin 1 item
  120. Influenza viruses 1 item
  121. ErbB 5item
  122. S6 kinases 1 item
  123. Toll-like receptors (TLRs) 4item
  124. Adenosine Kinases 2item
  125. Actin 1 item
  126. Serine Proteases 2item
  127. DNA Methyltransferases 4item
  128. Survivin 1 item
  129. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  130. ERK 8item
  131. HMG-CoA Reductases 6item
  132. c-MET 8item
  133. BMI-1 1 item
  134. PKC 14item
  135. Calpains 5item
  136. Ubiquitin-specific proteases 1 item
  137. M1 Receptors 1 item
  138. HCV Proteases 3item
  139. Ca2 /calmodulin-dependent protein kinases (CaMKs) 6item
  140. MLK3 1 item
  141. O-GlcNAcase 1 item
  142. CREBBP 1 item
  143. EP300 1 item
  144. Protease-Activated Receptors 1 item
  145. Lyn 2item
  146. SGLT 1 item
  147. RAD51 2item
  148. Trypsins 1 item
  149. HER2 3item
  150. Pyk2 3item
  151. USP 1 item
  152. 5-HT2 Receptors 6item
  153. LRRK2 6item
  154. Voltage-gated Calcium Channels (CaV) 2item
  155. Calcium chelator 1 item
  156. DGAT 2item
  157. Insulin and Insulin-like Receptors 4item
  158. PARP 7item
  159. CB1 Receptors 3item
  160. Pyruvate dehydrogenases (PDH) 2item
  161. ALK 10item
  162. ROS1 2item
  163. Sphingosine kinases (SphKs) 3item
  164. Trypsin 1 item
  165. Chymotrypsin 1 item
  166. Kallikrein 1 item
  167. Trypsinogen 1 item
  168. Monocarboxylate transporters (MCTs) 2item
  169. CETP 2item
  170. Dehydrogenase 1 item
  171. PKG 2item
  172. PKA 6item
  173. Myosin light chain kinases (MLCKs) 2item
  174. GPR30 1 item
  175. HIV-1 gp120 1 item
  176. D1 and D5 Receptors 1 item
  177. D2 Receptors 4item
  178. D3 Receptors 2item
  179. 5-HT1 Receptors 2item
  180. 5-HT7 Receptors 1 item
  181. MELK 1 item
  182. Serotonin reuptake 1 item
  183. Insulin-like growth factors (IGFs) 1 item
  184. CSF1R 1 item
  185. Bromodomain and Extra-Terminal motif (BET) 1 item
  186. Lactate Dehydrogenases (LDH) 2item
  187. MK2 2item
  188. Fatty-acid-binding proteins (FABPs) 1 item
  189. Angiotensin-Converting Enzymes (ACEs) 6item
  190. Tie-2 5item
  191. RSK 3item
  192. p70 S6K 1 item
  193. Free Fatty Acid Receptors 1 item
  194. phosphatases 2item
  195. Autophagy 4item
  196. ATM/ATR 5item
  197. COX 12item
  198. YAP 1 item
  199. CK1 1 item
  200. CK2 3item
  201. HIPK2 1 item
  202. HIPK3 1 item
  203. HIV Integrases 2item
  204. Pregnane X Receptors 1 item
  205. Squalene epoxidases 2item
  206. PRAK 1 item
  207. MAPKAP-K2 1 item
  208. Delayed rectifier outward potassium current (IKr) 1 item
  209. GpIIb/IIIa receptor 1 item
  210. Guanine nucleotide exchange factors (GEFs) 1 item
  211. 20S proteasomal chymotrypsin 1 item
  212. Geranylgeranyltransferase I 1 item
  213. Farnesyltransferase 1 item
  214. Nampt 3item
  215. eIF4F 1 item
  216. Cdc42 1 item
  217. SRPK1 1 item
  218. P2X Receptors 2item
  219. Glutaminases 2item
  220. Carbonic Anhydrases 7item
  221. Ron 1 item
  222. G9a 1 item
  223. BLM 1 item
  224. HSV 2item
  225. NADPH Oxidases 3item
  226. Calcium-activated chloride channels (CaCC) 1 item
  227. GPR35 1 item
  228. Aldehyde Dehydrogenases 2item
  229. Synthases/Synthetases 2item
  230. MAGL 2item
  231. Leukotriene and Related Receptors 1 item
  232. Histamine H1 Receptors 4item
  233. Na /K ATPases 3item
  234. P110 1 item
  235. Hck 2item
  236. Inositol-requiring enzyme 1 (IRE1) 2item
  237. Na /K /Cl- Symporters (NKCCs) 2item
  238. GABAA Receptors 1 item
  239. Phospholipases 1 item
  240. Monoamine oxidases (MAOs) 1 item
  241. Organic anion transporters (OATs) 1 item
  242. TRP Channel 3item
  243. RNA Polymerases 3item
  244. Norepinephrine transporter 1 item
  245. 5-HT Transporters 3item
  246. Xanthine oxidoreductases 1 item
  247. Dihydroorotate dehydrogenase 1 item
  248. Guanylyl Cyclases 1 item
  249. Histone Demethylases 2item
  250. MNK 2item
  251. 5-Lipoxygenases 1 item
  252. NO Donors / Precursors 2item
  253. CB2 Receptors 2item
  254. HIV-1 reverse transcriptase 1 item
  255. IL Receptors 2item
  256. CCL2 1 item
  257. Noradrenaline reuptake 1 item
  258. Norepinephrine transporters 1 item
  259. 15-lipoxygenases 1 item
  260. Calcium-Activated Potassium (KCa) Channels 2item
  261. AChE 3item
  262. Insulin Receptors 1 item
  263. IRG-1R 1 item
  264. cAMP 1 item
  265. Sulfonylurea receptors 1 item
  266. Cdc2-like kinase (Clk) 1 item
  267. eEF-2 1 item
  268. Inward Rectifier Potassium (Kir) Channels 3item
  269. CRTH2 1 item
  270. Cdc7 1 item
  271. Nuclear Receptors 1 item
  272. CMV 1 item
  273. ZAP-70 1 item
  274. Catechol O-Methyltransferase (COMT) 2item
  275. fibrinolysis 1 item
  276. Angiotensin AT1 Receptors 3item
  277. D4 Receptors 1 item
  278. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  279. NMDA receptor 1 item
  280. HBV Proteases 1 item
  281. Hydroxylases 2item
  282. Flk-1 1 item
  283. Papains 1 item
  284. Protein Arginine Methyltransferases 1 item
  285. IMPDH 1 item
  286. Na /Ca2 Exchangers (NCXs) 1 item
  287. NAE 2item
  288. Ubiquitin-activating Enzyme E1 2item
  289. SUMOylation 1 item
  290. ATGL 1 item
  291. BACE 1 item
  292. Cytidine deaminases 1 item
  293. angiogenesis 1 item
  294. Glucagon Receptors 1 item
  295. 15-PGDH 1 item
  296. DPP-4 5item
  297. PP4 1 item
  298. c-RET 3item
  299. Nonstructural protein 5B (NS5B) 1 item
  300. guanylyl cyclase 1 item
  301. ETA Receptors 2item
  302. ETB Receptors 1 item
  303. p70 rsk 3item
  304. voltage-gated chloride channels 1 item
  305. FPTase 1 item
  306. 5-HT1 Receptor 1 item
  307. Microtubule/Tubulin 1 item
  308. VEGFR3/FLT4 1 item
  309. NTRK1/TRKA 1 item
  310. CSF-1R/c-Fms 1 item
  311. Tryptophan hydroxylases (TPH) 2item
  312. ADAMs 1 item
  313. NMPRTase 1 item
  314. Bfl-1 1 item
  315. TAM kinase 1 item
  316. p53-MDM2 interaction 1 item
  317. nuclear export 1 item
  318. CRM1 1 item
  319. PTP 1 item
  320. KDR 2item
  321. Fyn kinase 1 item
  322. Trypsin-like protease 1 item
  323. AXL 1 item
  324. Glyoxalase I 1 item
  325. ERAD 1 item
  326. Dipeptidyl-peptidase II 1 item
  327. p53 5item
  328. metalloprotease 1 item
  329. HDAC 2item
  330. Antifungal 1 item
  331. 5-HT receptors 1 item
  332. sodium channel 3item
  333. c-Fms tyrosine kinase 1 item
  334. human lyase 1 item
  335. insulin 1 item
  336. Ub-conjugating enzyme (E2) complex 1 item
  337. Smoothened receptor 1 item
  338. cysteine protease 2item
  339. PPAR 1 item
  340. IKK 1 item
  341. MSK 1 item
  342. gp120-CD4 interaction 1 item
  343. HCV polymerase 2item
  344. Ftase 1 item
  345. PC-PLC 2item
  346. Elastases 1 item
  347. ATP synthase 1 item
  348. Glucosidases 1 item
  349. Vitamin D receptors (VDRs) 1 item
  350. Antibiotic 3item
  351. Mer tyrosine kinase 1 item
  352. Hec1 1 item
  353. neprilysin 1 item
  354. GLI 1 item
  355. decarboxylase 1 item
  356. Stem Cell Differentiation 1 item
  357. PP2A/Nkd interaction 1 item
  358. HMGCR 1 item
  359. ErbB-2 1 item
  360. adrenergic receptor 2item
  361. HIV 1 item
  362. 5-HT4 Receptor 1 item
  363. TRPA 1 item
  364. sterol demethylase 1 item
  365. PDK-1 1 item
  366. GAPDH 1 item
  367. Histone Acetyltransferases (HATs) 2item
  368. complex I of the mitochondrial electron transport chain 1 item
  369. F1 Fo-ATPase 1 item
  370. Prk 1 item
  371. potassium channel 1 item
  372. calcium channel 1 item
  373. Ribonucleotide Reductases 1 item
  374. Trx 1 item
  375. Tyrosinases 1 item
  376. Neurokinin receptor 1 item
  377. HSP70 1 item
  378. ICAM 1 item
  379. ITK 1 item
  380. HIF-PH 1 item
  381. troponin 1 item
  382. NUAK 1 item
  383. Rho 1 item
  384. Aryl hydrocarbon receptors (AHRs) 1 item
  385. Ubiquitin E3 Ligases 1 item
  386. DCLK2 1 item
  387. FAAH 1 item
  388. PTK 1 item
  389. integrase 1 item
  390. NOS 2item
  391. TYK2 2item
  392. MUSK 1 item
  393. MAP3K 1 item
  394. GPR3 1 item
  395. Adenosine Deaminases 2item
  396. mitochondrial pyruvate carrier (MPC) 1 item
  397. DNA gyrase 1 item
  398. prolactin secretion 1 item
  399. gonadotropin release 1 item
  400. DprE 1 item
  401. Vitamin D 1 item
  402. carnitine reabsorption 1 item
  403. Histamine receptors 1 item
  404. GluR 1 item
  405. 5-HT receptor 1 item
  406. dopamine receptors 1 item
  407. AMPA receptor 1 item
  408. 5-alpha Reductases 1 item
  409. Flk1 2item
  410. SAPK 1 item
  411. p21 1 item
  412. Prostaglandin synthesis 1 item
  413. Protein Tyrosine Phosphatases 1 item
  414. alkaline phosphatases 1 item
  415. ATPases 1 item
  416. glutamate release 1 item
  417. PAFR 1 item
  418. Aromatases 2item
  419. DHFR 1 item
  420. GARFT 1 item
  421. 5-HT 1 item
  422. FGR 1 item
  423. YES 2item
  424. Fyn 2item
  425. ARG 1 item
  426. Autotaxin 1 item
  427. UCH 1 item
  428. RHA 1 item
  429. HCV NS3-4A protease 1 item
  430. PKD 1 item
  431. Pyruvate kinases 1 item
  432. Thioredoxin Reductases 1 item
  433. enoyl-acyl-carrier protein reductase 1 item
  434. SHIP 1 item
  435. MCL1 1 item
  436. Bcl-w 1 item
  437. glutathione peroxidase 4 1 item
  438. S-adenosylhomocysteine hydrolase 1 item
  439. Rho-kinase 1 item
  440. tropomyosin receptor kinase 1 item
  441. LSD 1 item
  442. DDX3 1 item
  443. PRMT 1 item
  444. ACE 1 item
  445. GLP 1 item
  446. SK 1 item
  447. MST 1 item
  448. PPK 1 item
  449. c-Syk 1 item
  450. CDK1/CyclinB 1 item
  451. NHE 1 item
  452. IDO 2item
  453. Tph 1 item
  454. PIM1 kinase 1 item
  455. phospholipase A2 1 item
  456. reverse transcriptase 1 item
  457. epoxide hydrolase 1 item
  458. Serotonin (5-HT) reuptake 1 item
  459. Cholesterol absorption 1 item
  460. Vascular Disrupting Agents (VDA) 1 item
  461. Androgen Receptor 1 item
  462. Substance P/NK1 Receptor 1 item
  463. gp120/CD4 1 item
  464. ATM 1 item
  465. Sirtuin 1 item
  466. NE 1 item
  467. PIKfyve 1 item
  468. Bax 1 item
  469. Glycogen Phosphorylases 1 item
  470. MTH1 1 item
  471. PTEN 1 item
  472. Insulin Receptor 1 item
  473. NS3/4a Proteases 1 item
  474. Ca2 -ATPases 1 item
  475. p90 S6K 1 item
  476. Dynamins 1 item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acne 1 item
  3. Acute Disseminated Candidiasis 1 item
  4. Acute Kidney Injury 3item
  5. Acute Lung Injury 1 item
  6. Acute Myelogenous Leukemia 5item
  7. Acute Myeloid Leukemia 26item
  8. Acute Renal Failure 1 item
  9. Adrenocortical Carcinoma 4item
  10. Advanced Renal Cell Carcinoma 1 item
  11. Autoimmune Diseases 1 item
  12. Biliary Cancer 1 item
  13. Bladder Cancer 11item
  14. Bladder Carcinoma 4item
  15. Bladder Diseases 2item
  16. B-lymphoid Malignancies 1 item
  17. Brain Injuries Studies 3item
  18. Breast Cancer 120item
  19. Cancer 527item
  20. Candida Peritonitis 1 item
  21. Candidemia 1 item
  22. Castration-resistant Prostate Cancer 1 item
  23. Cervical Cancer 6item
  24. Cholangiocarcinoma 2item
  25. Chronic Lymphocytic Leukemia 8item
  26. Chronic Myeloproliferative Disorders 1 item
  27. Clear Cell Renal Cell Carcinoma 2item
  28. Cocaine-Related Disorders 2item
  29. Colon Cancer 43item
  30. Colon Carcinoma 7item
  31. Colorectal Cancer 40item
  32. Depression 2item
  33. Diabetes 7item
  34. Diffuse Large B-cell Lymphoma 1 item
  35. Dyskinesia 1 item
  36. Dyslipidemia 2item
  37. Epilepsy 4item
  38. Erectile Dysfunction 4item
  39. Friedreich's Ataxia 2item
  40. Fungal Infection 1 item
  41. Fungi 1 item
  42. Glioblastoma 33item
  43. Glioma 17item
  44. HCV 4item
  45. Heart Failure 6item
  46. Hepatic Cancer 2item
  47. Hepatitis C 4item
  48. Hepatocellular Carcinoma 8item
  49. HIV 14item
  50. HIV Infections 11item
  51. Hypercholesterolemia 3item
  52. Immunological Diseases 1 item
  53. Inflammation 1 item
  54. Inflammatory Bowel Disease 1 item
  55. Inflammatory Diseases 19item
  56. Influenza 3item
  57. Kidney Injury Studies 3item
  58. Leukemia 26item
  59. Liver Cancer 3item
  60. Lung Cancer 42item
  61. Lung Carcinoma 4item
  62. Lymphoma 31item
  63. Mantle Cell Lymphoma 2item
  64. Medulloblastoma 1 item
  65. Melanoma 35item
  66. Mixed Lineage Leukemia 3item
  67. Multiple Myeloma 21item
  68. Myelofibrosis 2item
  69. Myeloma 7item
  70. Neuroblastoma 14item
  71. Neurocognitive Disorders 1 item
  72. Neuronal Protection 1 item
  73. Non-small Cell Lung Cancer 26item
  74. Non-small Cell Lung Carcinoma 2item
  75. Obsessive-Compulsive Disorder 1 item
  76. Osteoporosis 2item
  77. Ovarian Cancer 35item
  78. Pancreatic Cancer 49item
  79. Pancreatic Carcinoma 3item
  80. Pentacyclic Triterpenoid 1 item
  81. Prostate Cancer 56item
  82. Psoriasis 4item
  83. Psoriasis Vulgaris 1 item
  84. Pulmonary Arterial Hypertension 2item
  85. Pulmonary Fibrosis 2item
  86. Renal Cancer 4item
  87. Renal Cell Carcinoma 9item
  88. Rheumatoid Arthritis 14item
  89. Sarcoma 1 item
  90. Schizophrenia 9item
  91. Sleep Disorders 2item
  92. Soft Tissue Sarcoma 1 item
  93. Squamous Cell Carcinoma 2item
  94. Testicular Cancer 2item
  95. Thyroid Cancer 6item
  96. Tuberculosis 4item
  97. Type 2 Diabetes 17item