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  • Search results for: 'cdk4 inhibitor'

Search results for: 'cdk4 inhibitor'

Items 121-130 of 172

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  1. GDC-0941 dimethanesulfonate
    A3432 GDC-0941 dimethanesulfonate
    Summary: PI3K inhibitor
      insoluble in H2O; insoluble in EtOH; ≥207.6 mg/mL
  2. GDC-0084
    B7826 GDC-0084
    Summary: PI3K and mTOR inhibitor, brain-permeable
      insoluble in H2O; insoluble in EtOH; ≥2.83 mg/mL
  3. PI-103 Hydrochloride
    A3724 PI-103 Hydrochloride
    Target: PI3K|mTOR|DNA-PK
    Summary: DNA-PK/PI 3-kinase/mTOR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥19.25 mg/mL
  4. VS-5584 (SB2343)
    A3927 VS-5584 (SB2343)
    Target: PI3K|mTOR
    Summary: MTOR/P13K inhibitor,potent and selective
      insoluble in H2O; ≥17.7 mg/mL
  5. Torin 1
    A8312 Torin 1
     7 Citation
    Target: mTOR
    Summary: MTOR inhibitor,potent and selective
  6. Duvelisib (IPI-145, INK1197)
    A1720 Duvelisib (IPI-145, INK1197)
    Target: PI3K
    Summary: PI3K-δ/PI3K-γ inhibitor
      ≥20.84 mg/mL
  7. AZD1080
    B1536 AZD1080
     1 Citation
    Target: GSK-3
    Summary: GSK3βinhibitor
      insoluble in H2O; insoluble in EtOH; ≥16.7 mg/mL
  8. CAL-130 Hydrochloride
    A3268 CAL-130 Hydrochloride
    Summary: PI3K inhibitor
      Soluble in DMSO
  9. GSK690693
    A5072 GSK690693
    Target: Akt|PKC|PKG|PKA|Prk
    Summary: Pan-AKT inhibitor,ATP-competitive and potent
      ≥21.25 mg/mL
  10. SAR245409 (XL765)
    A5634 SAR245409 (XL765)
    Summary: mTOR/PI3K inhibitor
      insoluble in H2O; insoluble in EtOH; ≥15 mg/mL

Items 121-130 of 172

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  1. Category PI3K/Akt/mTOR Signaling Remove This Item
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Category
  1. Akt 26item
  2. AMPK 5item
  3. CK2 8item
  4. DNA-PK 5item
  5. eNOS 2item
  6. GSK-3 17item
  7. MELK 2item
  8. mTOR 29item
  9. PI3K 60item
  10. PI4K 1 item
  11. PDK-1 8item
  12. PIKfyve 1 item
  13. PKB 1 item
  14. S6 Kinase 8item
Specificity
  1. Selective 61item
Reversibility
  1. Reversible 4item
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 2item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 13item
  4. PI3K 35item
  5. mTOR 22item
  6. GSK-3 10item
  7. Eph Receptors 1 item
  8. VEGFR 1 item
  9. PDGFR 1 item
  10. Bcr-Abl 1 item
  11. Pim 1 item
  12. Ribosomal s6 kinases (RSK) 1 item
  13. Src 1 item
  14. DNA-PK 8item
  15. AMPK 2item
  16. S6 kinases 1 item
  17. ERK 1 item
  18. PKC 2item
  19. PKG 1 item
  20. PKA 3item
  21. MELK 1 item
  22. NUAK1 1 item
  23. NUAK2 1 item
  24. RSK 1 item
  25. ATM/ATR 2item
  26. CK2 3item
  27. HIPK2 1 item
  28. HIPK3 1 item
  29. P110 1 item
  30. Hck 1 item
  31. p70 rsk 3item
  32. PDK-1 1 item
  33. Prk 1 item
  34. NUAK 1 item
  35. NOS 1 item
  36. PIM1 kinase 1 item
  37. phospholipase A2 1 item
  38. ATM 1 item
  39. PIKfyve 1 item
  40. p90 S6K 1 item
Reported Experiments
  1. Animal Experiments 79item
  2. Cell Experiments 60item
Related Disease
  1. Adrenocortical Carcinoma 1 item
  2. Bladder Cancer 1 item
  3. Bladder Carcinoma 1 item
  4. Breast Cancer 14item
  5. Cancer 50item
  6. Cervical Cancer 1 item
  7. Cholangiocarcinoma 1 item
  8. Chronic Lymphocytic Leukemia 1 item
  9. Colon Cancer 3item
  10. Colon Carcinoma 1 item
  11. Colorectal Cancer 2item
  12. Diabetes 1 item
  13. Glioblastoma 5item
  14. Glioma 5item
  15. Hepatocellular Carcinoma 1 item
  16. Leukemia 1 item
  17. Lung Cancer 6item
  18. Melanoma 2item
  19. Neuroblastoma 2item
  20. Non-small Cell Lung Cancer 1 item
  21. Ovarian Cancer 4item
  22. Pancreatic Cancer 6item
  23. Prostate Cancer 5item
  24. Renal Cancer 1 item
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