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  • Search results for: 'cdk4 inhibitor'

Search results for: 'cdk4 inhibitor'

Items 41-50 of 90

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  1. Cobicistat (GS-9350)
    A4313 Cobicistat (GS-9350)
    Target: Cytochrome P450 (CYP450)
    Summary: Selective CYP3A inhibitor
      insoluble in H2O; ≥150.9 mg/mL
  2. Deltarasin
    A3358 Deltarasin
    Target: Phosphodiesterases (PDEs)
    Summary: KRAS-PDEδ interaction inhibitor
      Soluble in DMSO
  3. GSK180
    A8723 GSK180
    Target: Kynurenine-3-monooxygenase
    Summary: inhibitor of kynurenine-3-monooxygenase (KMO)
      ≥27.6 mg/mL
  4. Apremilast (CC-10004)
    A4317 Apremilast (CC-10004)
    Target: Phosphodiesterases (PDEs)
    Summary: PDE4 inhibitor
      ≥23.05 mg/mL
  5. FK866 (APO866)
    A4381 FK866 (APO866)
     1 Citation
    Target: Nampt
    Summary: NAMPT inhibitor, non-competitive, highly specific
      insoluble in H2O; ≥19.6 mg/mL
  6. AN-2728
    A3178 AN-2728
    Summary: PDE4 inhibitor,anti-inflammatory compound
      insoluble in H2O; ≥12.55 mg/mL
  7. Atorvastatin Calcium
    A4367 Atorvastatin Calcium
    Target: HMG-CoA Reductases
    Summary: HMG-CoA reductase inhibitor
      ≥57.75 mg/mL
  8. Pitavastatin Calcium
    A8504 Pitavastatin Calcium
     1 Citation
    Target: HMG-CoA Reductases
    Summary: Enzyme HMGCR inhibitor
      ≥34.85 mg/mL
  9. Varespladib (LY315920)
    A4356 Varespladib (LY315920)
    Target: Phospholipases
    Summary: HnsPLA inhibitor,potent and selective
  10. AZD7687
    A3215 AZD7687
    Target: DGAT
    Summary: DGAT inhibitor,potent and selective
      Soluble in DMSO

Items 41-50 of 90

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Category
  1. 5-alpha Reductase 1 item
  2. 5-Lipoxygenase 1 item
  3. Aminopeptidase 1 item
  4. C14ɑ demethylase 1 item
  5. Carbonic Anhydrase 3item
  6. CETP 2item
  7. Cholesterol absorption 1 item
  8. CYP3A/CYP450 3item
  9. Dehydrogenase 5item
  10. DHFR 1 item
  11. DGAT 1 item
  12. Dopamine β-hydroxylase 3item
  13. FAAH 1 item
  14. Factor Xa 1 item
  15. Ferroptosis 1 item
  16. HMG-CoA Reductase 7item
  17. HSP 11item
  18. IDO 4item
  19. KRAS-PDEδ 1 item
  20. Lipid Metabolism 2item
  21. Oxidative Phosphorylation 1 item
  22. P450 3item
  23. PDE 18item
  24. Phospholipase 2item
  25. SCD 1 item
  26. SGLT 1 item
  27. TPH 3item
  28. Transferase 7item
  29. monooxygenase 1 item
  30. Hydrolase 2item
Specificity
  1. Selective 58item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 1 item
  2. Irreversible 3item
Target
  1. Acyl coenzyme A: cholesterol acyltransferases 1 item
  2. Factor Xa 1 item
  3. Phosphodiesterases (PDEs) 16item
  4. Thymidylate Synthase 1 item
  5. Kynurenine-3-monooxygenase 1 item
  6. Aminopeptidases 1 item
  7. Stearoyl-CoA 9-desaturase (SCD-1) 2item
  8. HSP90 9item
  9. Cytochrome P450 (CYP450) 6item
  10. HMG-CoA Reductases 6item
  11. SGLT 1 item
  12. DGAT 2item
  13. Pyruvate dehydrogenases (PDH) 1 item
  14. CETP 2item
  15. Lactate Dehydrogenases (LDH) 2item
  16. Fatty-acid-binding proteins (FABPs) 1 item
  17. Nampt 1 item
  18. Carbonic Anhydrases 3item
  19. Aldehyde Dehydrogenases 1 item
  20. Phospholipases 1 item
  21. Catechol O-Methyltransferase (COMT) 1 item
  22. Hydroxylases 1 item
  23. FPTase 1 item
  24. Tryptophan hydroxylases (TPH) 2item
  25. sodium channel 1 item
  26. Ftase 1 item
  27. PC-PLC 1 item
  28. HMGCR 1 item
  29. adrenergic receptor 1 item
  30. sterol demethylase 1 item
  31. GAPDH 1 item
  32. complex I of the mitochondrial electron transport chain 1 item
  33. potassium channel 1 item
  34. calcium channel 1 item
  35. FAAH 1 item
  36. carnitine reabsorption 1 item
  37. 5-alpha Reductases 1 item
  38. DHFR 1 item
  39. GARFT 1 item
  40. glutathione peroxidase 4 1 item
  41. S-adenosylhomocysteine hydrolase 1 item
  42. IDO 1 item
  43. Tph 1 item
  44. epoxide hydrolase 1 item
  45. Cholesterol absorption 1 item
  46. Glycogen Phosphorylases 1 item
Related Disease
  1. Acne 1 item
  2. Acute Kidney Injury 1 item
  3. Acute Myeloid Leukemia 2item
  4. Bladder Cancer 1 item
  5. Bladder Carcinoma 1 item
  6. Brain Injuries Studies 1 item
  7. Breast Cancer 7item
  8. Cancer 30item
  9. Chronic Lymphocytic Leukemia 1 item
  10. Cocaine-Related Disorders 2item
  11. Colon Cancer 1 item
  12. Diabetes 2item
  13. Dyslipidemia 1 item
  14. Epilepsy 2item
  15. Erectile Dysfunction 4item
  16. Fungi 1 item
  17. Glioblastoma 1 item
  18. Glioma 1 item
  19. Hepatic Cancer 1 item
  20. HIV Infections 1 item
  21. Hypercholesterolemia 3item
  22. Inflammation 1 item
  23. Inflammatory Diseases 1 item
  24. Kidney Injury Studies 1 item
  25. Leukemia 1 item
  26. Lung Cancer 3item
  27. Lymphoma 1 item
  28. Melanoma 6item
  29. Multiple Myeloma 2item
  30. Neuroblastoma 2item
  31. Neurocognitive Disorders 1 item
  32. Non-small Cell Lung Cancer 2item
  33. Obsessive-Compulsive Disorder 1 item
  34. Osteoporosis 1 item
  35. Pancreatic Cancer 2item
  36. Pancreatic Carcinoma 1 item
  37. Prostate Cancer 7item
  38. Psoriasis 2item
  39. Psoriasis Vulgaris 1 item
  40. Pulmonary Arterial Hypertension 1 item
  41. Rheumatoid Arthritis 1 item
  42. Schizophrenia 2item
  43. Type 2 Diabetes 2item