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Search results for: 'cdk4 inhibitor'

Items 31-40 of 470

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  1. JNJ-7706621
    A4115 JNJ-7706621
     1 Citation
    Target: Cyclin-Dependent Kinases|Aurora Kinases
    Summary: Potent CDK/Aurora kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥19.7 mg/mL
  2. AG-490
    A4139 AG-490
     3 Citation
    Target: EGFR|JAK
    Summary: JAK2/EGFR inhibitor
      insoluble in H2O; ≥14.7 mg/mL
  3. Perindopril
    B1214 Perindopril
    Target: Angiotensin-Converting Enzymes (ACEs)
    Summary: ACE inhibitor
      Soluble in DMSO
  4. MLN8054
    A4114 MLN8054
    Target: Aurora Kinases
    Summary: Aurora A inhibitor
      insoluble in EtOH; insoluble in H2O; ≥39.05 mg/mL
  5. Thioridazine HCl
    A8537 Thioridazine HCl
    Target: Cytochrome P450 (CYP450)|D1 and D5 Receptors|D2 Receptors|D3 Receptors|D4 Receptors
    Summary: Calcium channel protein inhibitor
  6. K02288
    B2286 K02288
    Target: ALK
    Summary: ALK inhibitor
      insoluble in H2O; ≥17.6 mg/mL
  7. HS-173
    B4492 HS-173
    Target: PI3K
    Summary: novel PI3K inhibitor
      ≥21.1 mg/mL
  8. CCT128930 HCl
    A8617 CCT128930 HCl
    Target: Akt
    Summary: AKT inhibitor
      insoluble in H2O; ≥17.1 mg/mL
  9. AS 1949490
    B7483 AS 1949490
    Target: SHIP
    Summary: Selective SHIP2 inhibitor
  10. Beta-Lapachone
    B2290 Beta-Lapachone
    Target: Topoisomerases
    Summary: DNA topoisomerase I inhibitor,selective
      insoluble in H2O; ≥10.85 mg/mL

Items 31-40 of 470

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Category
  1. Signaling Pathways 452item
  2. Natural Products 2item
  3. Lab Reagents 2item
Reversibility
  1. Reversible 25item
  2. Irreversible 13item
Target
  1. Caspases 4item
  2. Cyclin-Dependent Kinases 14item
  3. Proteasome 8item
  4. Cathepsins 5item
  5. Histone Deacetylases (HDACs) 18item
  6. Akt 4item
  7. Bcl-2 5item
  8. PI3K 16item
  9. CXCR 2item
  10. Raf 7item
  11. Aurora Kinases 9item
  12. Bcl-xl 3item
  13. CSF-1R 2item
  14. Glycoproteins 1 item
  15. p97 1 item
  16. MDM2 1 item
  17. EZH2 3item
  18. mTOR 9item
  19. Bromodomains 4item
  20. AP-1 1 item
  21. MMP 6item
  22. Thymidine Phosphorylases 1 item
  23. Androgen Receptors 2item
  24. Peptidylprolyl isomerases 1 item
  25. Acyl coenzyme A: cholesterol acyltransferases 1 item
  26. Myosin II ATPases 1 item
  27. DT-diaphorases 1 item
  28. MER 1 item
  29. FLT3 9item
  30. GSK-3 5item
  31. Factor Xa 3item
  32. P-glycoprotein (P-gp) 3item
  33. PLK 5item
  34. Chk 4item
  35. Eph Receptors 2item
  36. VEGFR 14item
  37. PDGFR 11item
  38. c-Kit 3item
  39. RET 1 item
  40. Bromodomain-containing proteins(BRDs) 1 item
  41. Phosphodiesterases (PDEs) 6item
  42. Mcl-1 3item
  43. Hydrolase 1 item
  44. Thymidylate Synthase 2item
  45. p38 6item
  46. PKB 1 item
  47. JNK 1 item
  48. Bcr-Abl 5item
  49. MEK 7item
  50. PORCN 1 item
  51. DOT1L 1 item
  52. FGFR 2item
  53. Pim 4item
  54. Deubiquitinating enzymes (DUBs) 2item
  55. Smoothened 1 item
  56. MET 5item
  57. Src 5item
  58. Trk Receptors 3item
  59. STAT 4item
  60. EGFR 9item
  61. ROCK 2item
  62. Hypoxia Inducible Factors (HIFs) 1 item
  63. FAK 2item
  64. JAK 8item
  65. Syk 4item
  66. EZH1 1 item
  67. DNA-PK 4item
  68. HSP90 6item
  69. AMPK 1 item
  70. CFTR 2item
  71. Topoisomerases 5item
  72. Cytochrome P450 (CYP450) 4item
  73. Renin 1 item
  74. ErbB 1 item
  75. Toll-like receptors (TLRs) 1 item
  76. Actin 1 item
  77. DNA Methyltransferases 1 item
  78. ERK 4item
  79. HMG-CoA Reductases 3item
  80. c-MET 6item
  81. PKC 4item
  82. Calpains 3item
  83. Ca2 /calmodulin-dependent protein kinases (CaMKs) 4item
  84. Pyk2 2item
  85. USP 1 item
  86. 5-HT2 Receptors 3item
  87. LRRK2 3item
  88. Voltage-gated Calcium Channels (CaV) 1 item
  89. DGAT 1 item
  90. Insulin and Insulin-like Receptors 3item
  91. PARP 4item
  92. CB1 Receptors 1 item
  93. ALK 2item
  94. Sphingosine kinases (SphKs) 1 item
  95. CETP 1 item
  96. Myosin light chain kinases (MLCKs) 1 item
  97. D1 and D5 Receptors 1 item
  98. D2 Receptors 3item
  99. D3 Receptors 2item
  100. 5-HT1 Receptors 2item
  101. 5-HT7 Receptors 1 item
  102. Lactate Dehydrogenases (LDH) 1 item
  103. MK2 1 item
  104. Angiotensin-Converting Enzymes (ACEs) 3item
  105. Tie-2 2item
  106. RSK 1 item
  107. phosphatases 1 item
  108. Autophagy 1 item
  109. ATM/ATR 4item
  110. COX 6item
  111. CK2 3item
  112. HIPK2 1 item
  113. HIPK3 1 item
  114. HIV Integrases 1 item
  115. Squalene epoxidases 1 item
  116. PRAK 1 item
  117. MAPKAP-K2 1 item
  118. GpIIb/IIIa receptor 1 item
  119. Guanine nucleotide exchange factors (GEFs) 1 item
  120. 20S proteasomal chymotrypsin 1 item
  121. Geranylgeranyltransferase I 1 item
  122. Farnesyltransferase 1 item
  123. Nampt 2item
  124. eIF4F 1 item
  125. Cdc42 1 item
  126. SRPK1 1 item
  127. P2X Receptors 1 item
  128. Glutaminases 1 item
  129. Carbonic Anhydrases 6item
  130. Ron 1 item
  131. G9a 1 item
  132. BLM 1 item
  133. HSV 1 item
  134. NADPH Oxidases 2item
  135. Calcium-activated chloride channels (CaCC) 1 item
  136. GPR35 1 item
  137. Aldehyde Dehydrogenases 1 item
  138. Synthases/Synthetases 2item
  139. MAGL 1 item
  140. Histamine H1 Receptors 1 item
  141. Na /K ATPases 2item
  142. P110 1 item
  143. Hck 1 item
  144. Inositol-requiring enzyme 1 (IRE1) 2item
  145. Na /K /Cl- Symporters (NKCCs) 1 item
  146. GABAA Receptors 1 item
  147. Phospholipases 1 item
  148. Organic anion transporters (OATs) 1 item
  149. TRP Channel 1 item
  150. RNA Polymerases 1 item
  151. Norepinephrine transporter 1 item
  152. 5-HT Transporters 3item
  153. Xanthine oxidoreductases 1 item
  154. Dihydroorotate dehydrogenase 1 item
  155. Histone Demethylases 1 item
  156. MNK 1 item
  157. NO Donors / Precursors 2item
  158. CB2 Receptors 1 item
  159. HIV-1 reverse transcriptase 1 item
  160. IL Receptors 2item
  161. CCL2 1 item
  162. Noradrenaline reuptake 1 item
  163. Norepinephrine transporters 1 item
  164. Calcium-Activated Potassium (KCa) Channels 1 item
  165. AChE 2item
  166. Insulin Receptors 1 item
  167. IRG-1R 1 item
  168. cAMP 1 item
  169. Sulfonylurea receptors 1 item
  170. Cdc2-like kinase (Clk) 1 item
  171. eEF-2 1 item
  172. Inward Rectifier Potassium (Kir) Channels 2item
  173. Cdc7 1 item
  174. CMV 1 item
  175. ZAP-70 1 item
  176. Catechol O-Methyltransferase (COMT) 2item
  177. fibrinolysis 1 item
  178. D4 Receptors 1 item
  179. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  180. HBV Proteases 1 item
  181. Flk-1 1 item
  182. Papains 1 item
  183. Protein Arginine Methyltransferases 1 item
  184. IMPDH 1 item
  185. Na /Ca2 Exchangers (NCXs) 1 item
  186. NAE 2item
  187. Ubiquitin-activating Enzyme E1 1 item
  188. SUMOylation 1 item
  189. ATGL 1 item
  190. BACE 1 item
  191. Cytidine deaminases 1 item
  192. angiogenesis 1 item
  193. Glucagon Receptors 1 item
  194. 15-PGDH 1 item
  195. DPP-4 4item
  196. c-RET 1 item
  197. Nonstructural protein 5B (NS5B) 1 item
  198. p70 rsk 1 item
  199. FPTase 1 item
  200. ADAMs 1 item
  201. TAM kinase 1 item
  202. p53-MDM2 interaction 1 item
  203. nuclear export 1 item
  204. CRM1 1 item
  205. AXL 1 item
  206. Protein polybromo-1 1 item
  207. SMARCA4 1 item
  208. SMARCA2 1 item
  209. Dipeptidyl-peptidase II 1 item
  210. HDAC 1 item
  211. c-Fms tyrosine kinase 1 item
  212. human lyase 1 item
  213. Ub-conjugating enzyme (E2) complex 1 item
  214. STK 1 item
  215. IKK 1 item
  216. MSK 1 item
  217. HCV polymerase 2item
  218. Ftase 1 item
  219. PC-PLC 1 item
  220. Elastases 1 item
  221. P97 ATPase 1 item
  222. NTPDases 1 item
  223. telomerase 1 item
  224. Histone Acetyltransferases (HATs) 1 item
  225. F1 Fo-ATPase 1 item
  226. ITK 1 item
  227. NOD1 1 item
  228. NUAK 1 item
  229. DCLK2 1 item
  230. FAAH 1 item
  231. TYK2 1 item
  232. Lck 1 item
  233. Aromatases 1 item
  234. PKD 1 item
  235. SHIP 1 item
  236. MCL1 1 item
  237. Bcl-w 1 item
  238. tropomyosin receptor kinase 1 item
  239. LSD 1 item
  240. PRMT 1 item
  241. GLP 1 item
  242. SK 1 item
  243. MST 1 item
  244. IDO 1 item
  245. Serotonin (5-HT) reuptake 1 item
  246. Androgen Receptor 1 item
  247. Substance P/NK1 Receptor 1 item
  248. gp120/CD4 1 item
  249. ATM 1 item
  250. Sirtuin 1 item
  251. NE 1 item
  252. PIKfyve 1 item
  253. Glycogen Phosphorylases 1 item
  254. MTH1 1 item
  255. Insulin Receptor 1 item
Related Disease
  1. Acne 1 item
  2. Acute Kidney Injury 1 item
  3. Acute Lung Injury 1 item
  4. Acute Myelogenous Leukemia 4item
  5. Acute Myeloid Leukemia 18item
  6. Acute Renal Failure 1 item
  7. Adrenocortical Carcinoma 3item
  8. Biliary Cancer 1 item
  9. Bladder Cancer 8item
  10. Bladder Carcinoma 3item
  11. Bladder Diseases 2item
  12. B-lymphoid Malignancies 1 item
  13. Brain Injuries Studies 3item
  14. Breast Cancer 67item
  15. Cancer 237item
  16. Castration-resistant Prostate Cancer 1 item
  17. Cervical Cancer 4item
  18. Cholangiocarcinoma 1 item
  19. Chronic Lymphocytic Leukemia 6item
  20. Chronic Myeloproliferative Disorders 1 item
  21. Clear Cell Renal Cell Carcinoma 1 item
  22. Cocaine-Related Disorders 2item
  23. Colon Cancer 23item
  24. Colon Carcinoma 3item
  25. Colorectal Cancer 28item
  26. Depression 2item
  27. Diabetes 6item
  28. Diffuse Large B-cell Lymphoma 1 item
  29. Dyskinesia 1 item
  30. Dyslipidemia 2item
  31. Epilepsy 1 item
  32. Erectile Dysfunction 2item
  33. Friedreich's Ataxia 2item
  34. Glioblastoma 18item
  35. Glioma 10item
  36. HCV 1 item
  37. Heart Failure 1 item
  38. Hepatitis C 2item
  39. Hepatocellular Carcinoma 4item
  40. HIV 2item
  41. HIV Infections 8item
  42. Inflammation 1 item
  43. Inflammatory Diseases 4item
  44. Kidney Injury Studies 1 item
  45. Leukemia 14item
  46. Liver Cancer 2item
  47. Lung Cancer 21item
  48. Lung Carcinoma 2item
  49. Lymphoma 24item
  50. Mantle Cell Lymphoma 2item
  51. Melanoma 17item
  52. Mixed Lineage Leukemia 1 item
  53. Multiple Myeloma 15item
  54. Myelofibrosis 2item
  55. Myeloma 2item
  56. Neuroblastoma 6item
  57. Neurocognitive Disorders 1 item
  58. Neuronal Protection 1 item
  59. Non-small Cell Lung Cancer 14item
  60. Non-small Cell Lung Carcinoma 1 item
  61. Obsessive-Compulsive Disorder 1 item
  62. Osteoporosis 2item
  63. Ovarian Cancer 22item
  64. Pancreatic Cancer 31item
  65. Pancreatic Carcinoma 1 item
  66. Prostate Cancer 35item
  67. Psoriasis 3item
  68. Psoriasis Vulgaris 1 item
  69. Pulmonary Fibrosis 2item
  70. Renal Cancer 3item
  71. Renal Cell Carcinoma 4item
  72. Rheumatoid Arthritis 11item
  73. Sarcoma 1 item
  74. Schizophrenia 5item
  75. Sleep Disorders 2item
  76. Soft Tissue Sarcoma 1 item
  77. Squamous Cell Carcinoma 2item
  78. Thyroid Cancer 4item
  79. Type 2 Diabetes 8item