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Search results for: 'cdk4 inhibitor'

Search results for: 'cdk4 inhibitor'

B3277 AMG 925

Target: Cyclin-Dependent Kinases|FLT3

Summary: FLT3/CDK4 inhibitor,potent and selective

insoluble in DMSO; insoluble in H2O; insoluble in EtOH
B8016 UNC2025

1 Citation

Target: MER|FLT3

Summary: orally bioavailable dual MER/FLT3 inhibitor

≥23.85 mg/mL
A2168 Dovitinib (TKI-258, CHIR-258)

2 Citation

Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR

Summary: Multitargeted RTK inhibitor

insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
A8476 MK-2461

Target: FLT3|PDGFR|MET|Ron

Summary: C-Met (WT/mutants) inhibitor

≥24.8 mg/mL
A5793 Quizartinib (AC220)

Target: FLT3

Summary: FLT3 inhibitor,potent and selective

≥28.03 mg/mL
B5832 Altiratinib

1 Citation

Target: FLT3|VEGFR|Trk Receptors|c-MET|Tie-2

Summary: c-MET/TIE-2/VEGFR inhibitor

≥21.55 mg/mL
A8394 CHIR-124

Target: FLT3|GSK-3|Chk|PDGFR

Summary: Chk1 inhibitor,novel and potent

insoluble in H2O; ≥10.5 mg/mL
A4136 TG101348 (SAR302503)

2 Citation

Target: FLT3|JAK|c-RET

Summary: JAK-2 inhibitor,potent and selective

≥26.23 mg/mL
B5835 AZD2932

Target: FLT3|VEGFR|PDGFR|c-Kit

Summary: inhibitor of VEGFR-2, PDGFRβ, Flt-3, and c-Kit

Soluble in DMSO