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  • Search results for: 'gsk 3 inhibitor 1'

Search results for: 'gsk 3 inhibitor 1'

Items 221-230 of 568

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  1. SU5416
    A3847 SU5416
    Target: VEGFR
    Summary: VEGF receptor inhibitor and AHR agonist
      insoluble in EtOH; insoluble in H2O; ≥11.9 mg/mL
  2. AG-1478
    A8357 AG-1478
    Target: EGFR
    Summary: EGFR inhibitor,potent and selective
      insoluble in H2O; ≥15.8 mg/mL
  3. SP2509
    B4894 SP2509
    Target: Histone Demethylases
    Summary: Demethylase 1 (LSD1) antagonist, novel Lysine-specific
      insoluble in H2O; insoluble in EtOH; ≥19.45 mg/mL
  4. GDC-0449 (Vismodegib)
    A3021 GDC-0449 (Vismodegib)
     1 Citation
    Target: P-glycoprotein (P-gp)|Hedgehog
    Summary: Hedgehog antagonist,potent and selective
      ≥21.08 mg/mL
  5. LY 294002
    A8250 LY 294002
     16 Citation
    Target: PI3K
    Summary: Potent PI3K inhibitor
  6. Cyclopamine
    A8340 Cyclopamine
     1 Citation
    Target: Smoothened
    Summary: Hedgehog (Hh) signaling Inhibitor
      insoluble in EtOH; insoluble in H2O; ≥6.86 mg/mL
  7. LY2784544
    A4147 LY2784544
    Target: Aurora Kinases|FLT3|VEGFR|FGFR|Trk Receptors|JAK|ALK|TYK2|MUSK|MAP3K
    Summary: JAK2 inhibitor,highly potent and selective
      ≥23.5 mg/mL
  8. BMS-911543
    A4152 BMS-911543
    Target: JAK
    Summary: JAK2 inhibitor,selective small molecule
      ≥43.3 mg/mL
  9. Silvestrol
    A3818 Silvestrol
    Summary: Antineoplastic
      Soluble in DMSO
  10. THZ1 Hydrochloride
    B4736 THZ1 Hydrochloride
    Target: Cyclin-Dependent Kinases
    Summary: CDK7 inhibitor
      ≥30.13 mg/mL

Items 221-230 of 568

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Category
  1. Proteases 34item
  2. Apoptosis 40item
  3. Chromatin/Epigenetics 85item
  4. Metabolism 32item
  5. MAPK Signaling 27item
  6. Tyrosine Kinase 109item
  7. DNA Damage/DNA Repair 59item
  8. PI3K/Akt/mTOR Signaling 51item
  9. Microbiology & Virology 5item
  10. Cell Cycle/Checkpoint 72item
  11. Ubiquitination/ Proteasome 29item
  12. JAK/STAT Signaling 35item
  13. TGF-β / Smad Signaling 22item
  14. Angiogenesis 6item
  15. GPCR/G protein 12item
  16. Stem Cell 25item
  17. Membrane Transporter/Ion Channel 6item
  18. Endocrinology and Hormones 8item
  19. Neuroscience 9item
  20. Others 31item
  21. Immunology/Inflammation 7item
Specificity
  1. Selective 455item
  2. Non-Selective 2item
Reversibility
  1. Reversible 28item
  2. Irreversible 22item
Target
  1. Caspases 4item
  2. Cyclin-Dependent Kinases 25item
  3. Proteasome 9item
  4. Cathepsins 2item
  5. Histone Deacetylases (HDACs) 24item
  6. Inhibitor of apoptosis proteins (IAP) 2item
  7. Akt 11item
  8. Bcl-2 8item
  9. PI3K 26item
  10. CXCR 2item
  11. Raf 11item
  12. Aurora Kinases 18item
  13. Bcl-xl 2item
  14. CSF-1R 4item
  15. Glycoproteins 1 item
  16. p97 1 item
  17. MDM2 2item
  18. EZH2 5item
  19. mTOR 15item
  20. Bromodomains 5item
  21. AP-1 1 item
  22. MMP 3item
  23. Thymidine Phosphorylases 1 item
  24. Androgen Receptors 4item
  25. DT-diaphorases 1 item
  26. FLT3 12item
  27. GSK-3 5item
  28. LPA Receptors 1 item
  29. P-glycoprotein (P-gp) 5item
  30. PLK 9item
  31. Chk 5item
  32. ULK1 1 item
  33. Eph Receptors 3item
  34. VEGFR 36item
  35. PDGFR 21item
  36. c-Kit 10item
  37. RET 4item
  38. Bromodomain-containing proteins(BRDs) 1 item
  39. Phosphodiesterases (PDEs) 3item
  40. Mcl-1 5item
  41. Thymidylate Synthase 3item
  42. p38 3item
  43. 3-phosphoglycerate dehydrogenase 1 item
  44. JNK 1 item
  45. SGK 2item
  46. Bcr-Abl 8item
  47. MEK 11item
  48. PORCN 1 item
  49. DOT1L 3item
  50. FGFR 13item
  51. Nrf2 1 item
  52. Insulin-like growth factor receptors(IGFRs) 1 item
  53. Pim 3item
  54. Liver X receptors (LXRs) 1 item
  55. Sir2-like Family Deacetylases (Sirtuins) 2item
  56. Deubiquitinating enzymes (DUBs) 4item
  57. PP1 1 item
  58. PP2A 1 item
  59. Smoothened 4item
  60. Ribosomal s6 kinases (RSK) 1 item
  61. MET 7item
  62. Src 9item
  63. Trk Receptors 5item
  64. Integrins 1 item
  65. Aminopeptidases 2item
  66. STAT 6item
  67. Microtubules/Tubulins 5item
  68. Estrogen and Related Receptors 2item
  69. EGFR 20item
  70. Hedgehog 1 item
  71. ROCK 1 item
  72. PAK 3item
  73. Hypoxia Inducible Factors (HIFs) 2item
  74. FAK 6item
  75. BMP and Other Activin Receptors 2item
  76. JAK 12item
  77. p300 1 item
  78. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  79. Syk 4item
  80. Progesterone Receptors 1 item
  81. EZH1 1 item
  82. DNA-PK 5item
  83. HSP90 12item
  84. AMPK 1 item
  85. Gutathione S-transferase 1 item
  86. CCR 1 item
  87. eIF4E/eIF3G interaction 1 item
  88. Notch 1 item
  89. TNKS 1 item
  90. Topoisomerases 9item
  91. Cytochrome P450 (CYP450) 4item
  92. Ksp 1 item
  93. ErbB 5item
  94. DNA Methyltransferases 3item
  95. Survivin 1 item
  96. ERK 4item
  97. HMG-CoA Reductases 2item
  98. Vacuolar-type ATPase 1 item
  99. c-MET 7item
  100. BMI-1 1 item
  101. PKC 11item
  102. Calpains 2item
  103. Ubiquitin-specific proteases 1 item
  104. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  105. SMYD2 1 item
  106. CREBBP 1 item
  107. EP300 1 item
  108. Lyn 1 item
  109. RAD51 2item
  110. HER2 2item
  111. Pyk2 3item
  112. 5-HT2 Receptors 2item
  113. Calcium chelator 1 item
  114. Insulin and Insulin-like Receptors 2item
  115. PARP 3item
  116. Pyruvate dehydrogenases (PDH) 1 item
  117. ALK 7item
  118. ROS1 2item
  119. Sphingosine kinases (SphKs) 2item
  120. KRAS G12C 1 item
  121. Monocarboxylate transporters (MCTs) 1 item
  122. Dehydrogenase 1 item
  123. PKG 2item
  124. PKA 5item
  125. Myosin light chain kinases (MLCKs) 1 item
  126. GPR30 1 item
  127. D1 and D5 Receptors 1 item
  128. D2 Receptors 2item
  129. D3 Receptors 1 item
  130. Valosin-containing protein (VCP) 1 item
  131. MELK 1 item
  132. Insulin-like growth factors (IGFs) 1 item
  133. Integrin-ligand interactions 1 item
  134. CSF1R 1 item
  135. Bromodomain and Extra-Terminal motif (BET) 1 item
  136. MK2 2item
  137. 5-HT3 Receptors 1 item
  138. Angiotensin-Converting Enzymes (ACEs) 1 item
  139. Tie-2 4item
  140. RSK 2item
  141. p70 S6K 1 item
  142. Autophagy 3item
  143. ATM/ATR 6item
  144. COX 3item
  145. Heparanases 1 item
  146. YAP 1 item
  147. CK1 1 item
  148. IDH2 1 item
  149. CK2 2item
  150. HIPK2 1 item
  151. HIPK3 1 item
  152. G-quadruplexes 1 item
  153. PRAK 1 item
  154. MAPKAP-K2 1 item
  155. 20S proteasomal chymotrypsin 1 item
  156. Geranylgeranyltransferase I 1 item
  157. Farnesyltransferase 1 item
  158. Nampt 3item
  159. eIF4F 1 item
  160. Cdc42 1 item
  161. P2X Receptors 1 item
  162. Glutaminases 2item
  163. Carbonic Anhydrases 1 item
  164. Ron 1 item
  165. BLM 1 item
  166. Aldehyde Dehydrogenases 1 item
  167. Synthases/Synthetases 2item
  168. MAGL 1 item
  169. P110 1 item
  170. Hck 1 item
  171. Inositol-requiring enzyme 1 (IRE1) 1 item
  172. iNOS 1 item
  173. Histamine H2 Receptors 1 item
  174. RNA Polymerases 1 item
  175. Norepinephrine transporter 1 item
  176. 5-HT Transporters 1 item
  177. Guanylyl Cyclases 1 item
  178. Histone Demethylases 1 item
  179. Apoptosis Inducers 1 item
  180. MNK 1 item
  181. Glucocorticoid Receptors 1 item
  182. HIV-1 reverse transcriptase 1 item
  183. Calcium-Activated Potassium (KCa) Channels 1 item
  184. Insulin Receptors 1 item
  185. IRG-1R 1 item
  186. cAMP 1 item
  187. Sulfonylurea receptors 1 item
  188. eEF-2 1 item
  189. Cdc7 1 item
  190. CMV 1 item
  191. ZAP-70 1 item
  192. Catechol O-Methyltransferase (COMT) 1 item
  193. fibrinolysis 1 item
  194. D4 Receptors 1 item
  195. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  196. Flk-1 1 item
  197. Papains 1 item
  198. Protein Arginine Methyltransferases 1 item
  199. NAE 2item
  200. Ubiquitin-activating Enzyme E1 1 item
  201. SUMOylation 1 item
  202. Cytidine deaminases 1 item
  203. angiogenesis 1 item
  204. DPP-4 1 item
  205. PP4 1 item
  206. c-RET 2item
  207. p70 rsk 2item
  208. VEGFR3/FLT4 1 item
  209. NTRK1/TRKA 1 item
  210. CSF-1R/c-Fms 1 item
  211. NMPRTase 1 item
  212. Bfl-1 1 item
  213. TAM kinase 1 item
  214. p53-MDM2 interaction 1 item
  215. nuclear export 1 item
  216. CRM1 1 item
  217. KDR 2item
  218. AXL 1 item
  219. Glyoxalase I 1 item
  220. p53 2item
  221. HDAC 1 item
  222. human lyase 1 item
  223. insulin 1 item
  224. Ub-conjugating enzyme (E2) complex 1 item
  225. Smoothened receptor 1 item
  226. Hec1 1 item
  227. GLI 1 item
  228. ErbB-2 1 item
  229. PDK-1 1 item
  230. Prk 1 item
  231. Ribonucleotide Reductases 1 item
  232. Trx 1 item
  233. HSP70 1 item
  234. TYK2 1 item
  235. MUSK 1 item
  236. MAP3K 1 item
  237. Adenosine Deaminases 1 item
  238. Flk1 2item
  239. DHFR 1 item
  240. GARFT 1 item
  241. RHA 1 item
  242. MCL1 1 item
  243. Bcl-w 1 item
  244. tropomyosin receptor kinase 1 item
  245. LSD 1 item
  246. DDX3 1 item
  247. SK 1 item
  248. PPK 1 item
  249. c-Syk 1 item
  250. CDK1/CyclinB 1 item
  251. IDO 1 item
  252. PIM1 kinase 1 item
  253. phospholipase A2 1 item
  254. Substance P/NK1 Receptor 1 item
  255. Bax 1 item
Reported Experiments
  1. Animal Experiments 524item
  2. Cell Experiments 354item