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  • Search results for: 'gsk 3 inhibitor 1'

Search results for: 'gsk 3 inhibitor 1'

Items 371-380 of 851

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  1. ARN-509
    A8364 ARN-509
     2 Citation
    Target: Androgen Receptor
    Summary: Androgen receptor inhibitor
      ≥23.85 mg/mL
  2. CGP 57380
    B3570 CGP 57380
    Target: MNK
    Summary: MNK1 inhibitor, specific and selective
      insoluble in EtOH; insoluble in H2O; ≥12.2 mg/mL
  3. SF1670
    B4787 SF1670
    Target: PTEN
    Summary: PTEN inhibitor, potent and specific
      insoluble in EtOH; insoluble in H2O; ≥15.37 mg/mL
  4. Ritonavir
    A8203 Ritonavir
    Summary: HIV protease inhibitor
      ≥26 mg/mL
  5. NMS-1286937
    B4094 NMS-1286937
    Target: PLK
    Summary: PLK1 inhibitor, orally bioavailable
      insoluble in H2O; insoluble in EtOH; ≥13.33 mg/mL
  6. TGX-221
    A2681 TGX-221
    Target: PI3K
    Summary: PI3Kβ inhibitor,potent,selective and ATP competitive
      insoluble in H2O; insoluble in EtOH; ≥68.7 mg/mL
  7. SMI-4a
    A4193 SMI-4a
    Target: Pim
    Summary: Potent Pim inhibitor
      insoluble in H2O; ≥13.65 mg/mL
  8. RAF265
    A8313 RAF265
    Target: Raf|VEGFR
    Summary: Multiple intracellular kinases inhibitor
      ≥25.9 mg/mL
  9. ABT-263 (Navitoclax)
    A3007 ABT-263 (Navitoclax)
     15 Citation
    Target: Bcl-2|Bcl-w
    Summary: Potent Bcl-2 family inhibitor, inhibits Bcl-2, Bcl-xL, and Bcl-w
      ≥48.73 mg/mL
  10. THZ1
    A8882 THZ1
     12 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Covalent CDK7 inhibitor,potent and selective
      ≥28.3 mg/mL

Items 371-380 of 851

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Category
  1. Proteases 69item
  2. Apoptosis 48item
  3. Chromatin/Epigenetics 100item
  4. Metabolism 79item
  5. MAPK Signaling 32item
  6. Tyrosine Kinase 98item
  7. DNA Damage/DNA Repair 69item
  8. PI3K/Akt/mTOR Signaling 61item
  9. Microbiology & Virology 41item
  10. Cell Cycle/Checkpoint 68item
  11. Ubiquitination/ Proteasome 27item
  12. JAK/STAT Signaling 36item
  13. TGF-β / Smad Signaling 29item
  14. Angiogenesis 6item
  15. GPCR/G protein 38item
  16. Stem Cell 26item
  17. Membrane Transporter/Ion Channel 35item
  18. Endocrinology and Hormones 20item
  19. Neuroscience 46item
  20. Obesity, Appetite Control & Diabetes 2item
  21. Other Signal Transduction 3item
  22. Others 74item
  23. Immunology/Inflammation 18item
  24. Cardiovascular 3item
  25. Vitamin D Related 3item
  26. NF-κB 1 item
Specificity
  1. Selective 510item
  2. Non-Selective 3item
Reversibility
  1. Reversible 34item
  2. Irreversible 27item
Target
  1. Caspases 7item
  2. Cyclin-Dependent Kinases 21item
  3. Proteasome 11item
  4. Cathepsins 5item
  5. Histone Deacetylases (HDACs) 26item
  6. Inhibitor of apoptosis proteins (IAP) 1 item
  7. Akt 11item
  8. Bcl-2 8item
  9. PI3K 28item
  10. CXCR 2item
  11. Raf 10item
  12. Aurora Kinases 18item
  13. Bcl-xl 3item
  14. CSF-1R 4item
  15. Glycoproteins 1 item
  16. p97 1 item
  17. Gap Junctions 1 item
  18. MDM2 2item
  19. EZH2 3item
  20. mTOR 16item
  21. Bromodomains 5item
  22. AP-1 3item
  23. MMP 7item
  24. Thymidine Phosphorylases 1 item
  25. Androgen Receptors 3item
  26. Peptidylprolyl isomerases 1 item
  27. Acyl coenzyme A: cholesterol acyltransferases 1 item
  28. Myosin II ATPases 1 item
  29. DT-diaphorases 1 item
  30. Voltage-gated Potassium (KV) Channels 1 item
  31. MER 1 item
  32. FLT3 16item
  33. GSK-3 6item
  34. Factor Xa 4item
  35. LPA Receptors 2item
  36. P-glycoprotein (P-gp) 3item
  37. PLK 9item
  38. Chk 4item
  39. Eph Receptors 2item
  40. VEGFR 28item
  41. PDGFR 19item
  42. c-Kit 9item
  43. RET 2item
  44. IRAK 2item
  45. Bromodomain-containing proteins(BRDs) 1 item
  46. Phosphodiesterases (PDEs) 12item
  47. Mcl-1 5item
  48. Hydrolase 1 item
  49. Thymidylate Synthase 3item
  50. p38 7item
  51. PKB 1 item
  52. JNK 2item
  53. Bcr-Abl 10item
  54. MEK 8item
  55. PORCN 1 item
  56. DOT1L 1 item
  57. FGFR 10item
  58. Nrf2 1 item
  59. Pim 3item
  60. Liver X receptors (LXRs) 2item
  61. Sir2-like Family Deacetylases (Sirtuins) 1 item
  62. Voltage-gated Sodium (NaV) Channels 2item
  63. Deubiquitinating enzymes (DUBs) 2item
  64. PP1 1 item
  65. PP2A 1 item
  66. Smoothened 1 item
  67. Neuraminidases (NA) 1 item
  68. MET 5item
  69. Src 15item
  70. Trk Receptors 5item
  71. Aminopeptidases 2item
  72. NMDA Receptors 2item
  73. STAT 6item
  74. Microtubules/Tubulins 1 item
  75. Estrogen and Related Receptors 2item
  76. EGFR 18item
  77. Reverse Transcriptases 5item
  78. ROCK 7item
  79. Hypoxia Inducible Factors (HIFs) 1 item
  80. FAK 3item
  81. JAK 17item
  82. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  83. Syk 4item
  84. Progesterone Receptors 2item
  85. EZH1 1 item
  86. DNA-PK 6item
  87. HSP90 8item
  88. AMPK 1 item
  89. CCR 1 item
  90. CFTR 2item
  91. Topoisomerases 13item
  92. Cytochrome P450 (CYP450) 8item
  93. Ksp 1 item
  94. Renin 1 item
  95. ErbB 4item
  96. Toll-like receptors (TLRs) 3item
  97. Actin 2item
  98. Serine Proteases 1 item
  99. DNA Methyltransferases 3item
  100. ERK 6item
  101. HMG-CoA Reductases 4item
  102. c-MET 6item
  103. PKC 11item
  104. Calpains 3item
  105. Ca2 /calmodulin-dependent protein kinases (CaMKs) 5item
  106. Protease-Activated Receptors 1 item
  107. Lyn 1 item
  108. RAD51 1 item
  109. HER2 1 item
  110. Pyk2 2item
  111. 5-HT2 Receptors 4item
  112. LRRK2 5item
  113. Voltage-gated Calcium Channels (CaV) 1 item
  114. DGAT 1 item
  115. Insulin and Insulin-like Receptors 4item
  116. PARP 6item
  117. CB1 Receptors 1 item
  118. Pyruvate dehydrogenases (PDH) 1 item
  119. ALK 6item
  120. Sphingosine kinases (SphKs) 2item
  121. Monocarboxylate transporters (MCTs) 1 item
  122. CETP 1 item
  123. PKG 2item
  124. PKA 5item
  125. Myosin light chain kinases (MLCKs) 2item
  126. GPR30 1 item
  127. D1 and D5 Receptors 1 item
  128. D2 Receptors 3item
  129. D3 Receptors 2item
  130. 5-HT1 Receptors 2item
  131. 5-HT7 Receptors 1 item
  132. Lactate Dehydrogenases (LDH) 2item
  133. MK2 2item
  134. 5-HT3 Receptors 1 item
  135. Angiotensin-Converting Enzymes (ACEs) 3item
  136. Tie-2 3item
  137. RSK 2item
  138. Free Fatty Acid Receptors 1 item
  139. phosphatases 1 item
  140. Autophagy 3item
  141. ATM/ATR 5item
  142. COX 10item
  143. YAP 1 item
  144. CK1 1 item
  145. Histamine H4 Receptors 2item
  146. CK2 4item
  147. HIPK2 1 item
  148. HIPK3 1 item
  149. HIV Integrases 1 item
  150. Squalene epoxidases 1 item
  151. PRAK 1 item
  152. MAPKAP-K2 1 item
  153. 20S proteasomal chymotrypsin 1 item
  154. Geranylgeranyltransferase I 1 item
  155. Farnesyltransferase 1 item
  156. Nampt 3item
  157. eIF4F 1 item
  158. Cdc42 1 item
  159. SRPK1 1 item
  160. P2X Receptors 2item
  161. Glutaminases 2item
  162. Carbonic Anhydrases 6item
  163. Ron 1 item
  164. G9a 1 item
  165. BLM 1 item
  166. HSV 2item
  167. NADPH Oxidases 3item
  168. Calcium-activated chloride channels (CaCC) 1 item
  169. GPR35 1 item
  170. Aldehyde Dehydrogenases 2item
  171. Synthases/Synthetases 2item
  172. MAGL 1 item
  173. NPY Receptors 1 item
  174. Leukotriene and Related Receptors 1 item
  175. Histamine H1 Receptors 5item
  176. RAR/RXR 1 item
  177. Na /K ATPases 2item
  178. P110 1 item
  179. Hck 2item
  180. Inositol-requiring enzyme 1 (IRE1) 1 item
  181. Na /K /Cl- Symporters (NKCCs) 2item
  182. GABAA Receptors 1 item
  183. Histamine H2 Receptors 1 item
  184. Phospholipases 1 item
  185. TRP Channel 2item
  186. RNA Polymerases 2item
  187. DYRK 1 item
  188. Norepinephrine transporter 1 item
  189. 5-HT Transporters 3item
  190. Xanthine oxidoreductases 1 item
  191. Dihydroorotate dehydrogenase 1 item
  192. Guanylyl Cyclases 1 item
  193. Histone Demethylases 1 item
  194. MNK 2item
  195. 5-Lipoxygenases 1 item
  196. NO Donors / Precursors 1 item
  197. CB2 Receptors 1 item
  198. Glucocorticoid Receptors 3item
  199. HIV-1 reverse transcriptase 1 item
  200. IL Receptors 2item
  201. CCL2 1 item
  202. Norepinephrine transporters 1 item
  203. 15-lipoxygenases 1 item
  204. Calcium-Activated Potassium (KCa) Channels 2item
  205. AChE 3item
  206. Insulin Receptors 1 item
  207. IRG-1R 1 item
  208. cAMP 1 item
  209. Sulfonylurea receptors 1 item
  210. eEF-2 1 item
  211. Inward Rectifier Potassium (Kir) Channels 2item
  212. CRTH2 1 item
  213. Cdc7 1 item
  214. Nuclear Receptors 1 item
  215. CMV 1 item
  216. ZAP-70 1 item
  217. Catechol O-Methyltransferase (COMT) 2item
  218. fibrinolysis 1 item
  219. Angiotensin AT1 Receptors 3item
  220. D4 Receptors 1 item
  221. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  222. NMDA receptor 1 item
  223. HBV Proteases 1 item
  224. Hydroxylases 2item
  225. Flk-1 1 item
  226. Adenine receptors 1 item
  227. Papains 1 item
  228. Protein Arginine Methyltransferases 1 item
  229. IMPDH 1 item
  230. Na /Ca2 Exchangers (NCXs) 1 item
  231. NAE 2item
  232. Ubiquitin-activating Enzyme E1 2item
  233. SUMOylation 1 item
  234. ATGL 1 item
  235. BACE 2item
  236. Cytidine deaminases 1 item
  237. angiogenesis 1 item
  238. Glucagon Receptors 1 item
  239. 15-PGDH 1 item
  240. DPP-4 5item
  241. PP4 1 item
  242. c-RET 3item
  243. Nonstructural protein 5B (NS5B) 1 item
  244. guanylyl cyclase 1 item
  245. ETA Receptors 2item
  246. ETB Receptors 1 item
  247. p70 rsk 3item
  248. voltage-gated chloride channels 1 item
  249. FPTase 1 item
  250. 5-HT1 Receptor 1 item
  251. Microtubule/Tubulin 1 item
  252. Myosin 1 item
  253. VEGFR3/FLT4 1 item
  254. NTRK1/TRKA 1 item
  255. CSF-1R/c-Fms 1 item
  256. interleukin receptor 1 item
  257. Menin-MLL 2item
  258. Tryptophan hydroxylases (TPH) 2item
  259. ADAMs 1 item
  260. NMPRTase 1 item
  261. Bfl-1 1 item
  262. TAM kinase 1 item
  263. p53-MDM2 interaction 2item
  264. nuclear export 1 item
  265. CRM1 1 item
  266. PTP 1 item
  267. KDR 2item
  268. Fyn kinase 1 item
  269. Abl kinases 1 item
  270. AXL 1 item
  271. Glyoxalase I 1 item
  272. dCTP Pyrophosphatases 1 item
  273. Protein polybromo-1 1 item
  274. SMARCA4 1 item
  275. SMARCA2 1 item
  276. Dipeptidyl-peptidase II 1 item
  277. p53 5item
  278. metalloprotease 1 item
  279. HDAC 2item
  280. Antifungal 1 item
  281. KDM 2item
  282. 5-HT receptors 1 item
  283. sodium channel 2item
  284. c-Fms tyrosine kinase 1 item
  285. PAR 1 item
  286. human lyase 1 item
  287. insulin 1 item
  288. Ub-conjugating enzyme (E2) complex 1 item
  289. Smoothened receptor 1 item
  290. quinone oxidoreductase 1 item
  291. cysteine protease 2item
  292. PPAR 1 item
  293. STK 1 item
  294. USP1/USF1 complex 1 item
  295. IKK 1 item
  296. MSK 1 item
  297. gp120-CD4 interaction 1 item
  298. TRPV 1 item
  299. HCV polymerase 3item
  300. Ftase 1 item
  301. Subtilisin/Kex2p-like proprotein convertase 1 item
  302. PC-PLC 2item
  303. Elastases 1 item
  304. P97 ATPase 1 item
  305. ATP synthase 1 item
  306. NTPDases 1 item
  307. Vitamin D receptors (VDRs) 2item
  308. Antibiotic 3item
  309. Mer tyrosine kinase 1 item
  310. Hec1 1 item
  311. EAA receptor 1 item
  312. neprilysin 1 item
  313. GLI 1 item
  314. Stem Cell Differentiation 1 item
  315. PP2A/Nkd interaction 1 item
  316. Rev-Erb Receptors 1 item
  317. HMGCR 1 item
  318. AAT 1 item
  319. ErbB-2 1 item
  320. adrenergic receptor 3item
  321. HIV 1 item
  322. 5-HT4 Receptor 1 item
  323. PAR receptor 1 item
  324. TRPA 1 item
  325. sterol demethylase 1 item
  326. PDK-1 1 item
  327. GAPDH 1 item
  328. telomerase 1 item
  329. Histone Acetyltransferases (HATs) 3item
  330. complex I of the mitochondrial electron transport chain 1 item
  331. F1 Fo-ATPase 1 item
  332. Prk 1 item
  333. potassium channel 1 item
  334. calcium channel 1 item
  335. Ribonucleotide Reductases 1 item
  336. Trx 1 item
  337. Tyrosinases 1 item
  338. Neurokinin receptor 1 item
  339. HSP70 1 item
  340. ICAM 1 item
  341. ITK 1 item
  342. HIF-PH 1 item
  343. NOD1 1 item
  344. NUAK 1 item
  345. Rho 1 item
  346. Aryl hydrocarbon receptors (AHRs) 1 item
  347. Ubiquitin E3 Ligases 1 item
  348. DCLK2 1 item
  349. FAAH 1 item
  350. PTK 1 item
  351. integrase 1 item
  352. L3MBTL 1 item
  353. phosphatidylinositol kinase 1 item
  354. NOS 2item
  355. MDMX 1 item
  356. TYK2 2item
  357. MUSK 1 item
  358. MAP3K 1 item
  359. GPR3 1 item
  360. AMPA Receptors 1 item
  361. Lck 1 item
  362. Adenosine Deaminases 2item
  363. mitochondrial pyruvate carrier (MPC) 1 item
  364. DNA gyrase 1 item
  365. prolactin secretion 1 item
  366. gonadotropin release 1 item
  367. DprE 1 item
  368. Vitamin D 1 item
  369. carnitine reabsorption 1 item
  370. Histamine receptors 1 item
  371. GluR 1 item
  372. 5-HT receptor 1 item
  373. dopamine receptors 1 item
  374. AMPA receptor 1 item
  375. 5-alpha Reductases 1 item
  376. Flk1 2item
  377. SAPK 1 item
  378. p21 1 item
  379. DNA Ligases 1 item
  380. NOP Receptors 1 item
  381. Prostaglandin synthesis 1 item
  382. Protein Tyrosine Phosphatases 1 item
  383. alkaline phosphatases 1 item
  384. ATPases 1 item
  385. glutamate release 1 item
  386. PAFR 1 item
  387. Aromatases 2item
  388. DHFR 1 item
  389. GARFT 1 item
  390. 5-HT 1 item
  391. PHF 1 item
  392. FGR 1 item
  393. YES 2item
  394. Fyn 2item
  395. ARG 1 item
  396. Autotaxin 1 item
  397. UCH 1 item
  398. RHA 1 item
  399. HCV NS3-4A protease 1 item
  400. PKD 1 item
  401. Octamer-binding transcription factor 4 (Oct4) 1 item
  402. Thioredoxin Reductases 1 item
  403. enoyl-acyl-carrier protein reductase 1 item
  404. SHIP 1 item
  405. MCL1 1 item
  406. Bcl-w 1 item
  407. glutathione peroxidase 4 1 item
  408. NADH oxidase 1 item
  409. S-adenosylhomocysteine hydrolase 1 item
  410. Rho-kinase 1 item
  411. tropomyosin receptor kinase 1 item
  412. LSD 1 item
  413. DDX3 1 item
  414. PRMT 1 item
  415. ACE 1 item
  416. GLP 1 item
  417. SK 1 item
  418. MST 1 item
  419. PPK 1 item
  420. c-Syk 1 item
  421. CDK1/CyclinB 1 item
  422. NHE 1 item
  423. IDO 1 item
  424. Tph 1 item
  425. PIM1 kinase 1 item
  426. phospholipase A2 1 item
  427. reverse transcriptase 1 item
  428. epoxide hydrolase 1 item
  429. ghrelin receptor 1 item
  430. Serotonin (5-HT) reuptake 1 item
  431. Cholesterol absorption 1 item
  432. Vascular Disrupting Agents (VDA) 1 item
  433. Androgen Receptor 1 item
  434. Substance P/NK1 Receptor 1 item
  435. gp120/CD4 1 item
  436. ATM 1 item
  437. Sirtuin 1 item
  438. NE 1 item
  439. CRF1 Receptors 1 item
  440. PIKfyve 1 item
  441. Bax 1 item
  442. Glycogen Phosphorylases 1 item
  443. MTH1 1 item
  444. PTEN 1 item
  445. Insulin Receptor 1 item
  446. NS3/4a Proteases 1 item
  447. p90 S6K 1 item
Related Disease
  1. Acne 2item
  2. Acute Kidney Injury 2item
  3. Acute Lung Injury 1 item
  4. Acute Myelogenous Leukemia 4item
  5. Acute Myeloid Leukemia 19item
  6. Acute Renal Failure 1 item
  7. Adrenocortical Carcinoma 3item
  8. Biliary Cancer 1 item
  9. Bladder Cancer 9item
  10. Bladder Carcinoma 3item
  11. Bladder Diseases 2item
  12. B-lymphoid Malignancies 1 item
  13. Brain Injuries Studies 3item
  14. Breast Cancer 74item
  15. Cancer 354item
  16. Castration-resistant Prostate Cancer 1 item
  17. Cervical Cancer 4item
  18. Cholangiocarcinoma 1 item
  19. Chronic Lymphocytic Leukemia 6item
  20. Chronic Myeloproliferative Disorders 1 item
  21. Clear Cell Renal Cell Carcinoma 1 item
  22. Cocaine-Related Disorders 2item
  23. Colon Cancer 22item
  24. Colon Carcinoma 3item
  25. Colorectal Cancer 28item
  26. Depression 2item
  27. Diabetes 7item
  28. Diffuse Large B-cell Lymphoma 1 item
  29. Dyskinesia 1 item
  30. Dyslipidemia 2item
  31. Epilepsy 3item
  32. Erectile Dysfunction 3item
  33. Friedreich's Ataxia 1 item
  34. Fungi 1 item
  35. Glioblastoma 19item
  36. Glioma 11item
  37. HCV 3item
  38. Heart Failure 6item
  39. Hepatitis C 3item
  40. Hepatocellular Carcinoma 5item
  41. HIV 11item
  42. HIV Infections 12item
  43. Hypercholesterolemia 1 item
  44. Inflammation 1 item
  45. Inflammatory Diseases 8item
  46. Influenza 1 item
  47. Kidney Injury Studies 2item
  48. Leukemia 18item
  49. Liver Cancer 2item
  50. Lung Cancer 19item
  51. Lung Carcinoma 2item
  52. Lymphoma 24item
  53. Mantle Cell Lymphoma 2item
  54. Melanoma 20item
  55. Mixed Lineage Leukemia 1 item
  56. Multiple Myeloma 15item
  57. Myelofibrosis 2item
  58. Myeloma 3item
  59. Narcolepsy 1 item
  60. Neuroblastoma 7item
  61. Neurocognitive Disorders 1 item
  62. Neuronal Protection 1 item
  63. Non-small Cell Lung Cancer 15item
  64. Non-small Cell Lung Carcinoma 1 item
  65. Obsessive-Compulsive Disorder 1 item
  66. Osteoporosis 2item
  67. Ovarian Cancer 21item
  68. Pancreatic Cancer 30item
  69. Pancreatic Carcinoma 1 item
  70. Pentacyclic Triterpenoid 1 item
  71. Prostate Cancer 37item
  72. Psoriasis 3item
  73. Psoriasis Vulgaris 1 item
  74. Pulmonary Fibrosis 2item
  75. Renal Cancer 3item
  76. Renal Cell Carcinoma 5item
  77. Rheumatoid Arthritis 11item
  78. Sarcoma 1 item
  79. Schizophrenia 5item
  80. Sleep Disorders 1 item
  81. Soft Tissue Sarcoma 1 item
  82. Squamous Cell Carcinoma 2item
  83. Thyroid Cancer 4item
  84. Tuberculosis 3item
  85. Type 2 Diabetes 10item