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  • Search results for: 'gsk 3 inhibitor 1'

Search results for: 'gsk 3 inhibitor 1'

Items 421-430 of 877

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  1. CCT251545
    B5979 CCT251545
    Summary: Orally bioavailable and potent WNT signaling inhibitor
      ≥42.2 mg/mL
  2. Rocilinostat (ACY-1215)
    A4083 Rocilinostat (ACY-1215)
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: Selective HDAC6 inhibitor
      ≥21.675 mg/mL
  3. KW 2449
    A4123 KW 2449
    Target: Aurora Kinases|FLT3|Bcr-Abl
    Summary: Multikinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥16.6 mg/mL
  4. Enzastaurin (LY317615)
    A1670 Enzastaurin (LY317615)
     2 Citation
    Target: PKC
    Summary: PKC beta inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥8.59 mg/mL
  5. GDC-0068 (RG7440)
    A3006 GDC-0068 (RG7440)
    Target: Akt
    Summary: Pan-AKT inhibitor,highly selective
      ≥22.9 mg/mL
  6. PFI-2
    B4875 PFI-2
     1 Citation
    Target: SETD7
    Summary: SETD7 methyltransferase inhibitor
      ≥50 mg/mL
  7. RG7112
    A3762 RG7112
     5 Citation
    Target: MDM2
    Summary: MDM2 inhibitor, first clinical
      ≥36.4 mg/mL
  8. Simeprevir
    A3820 Simeprevir
     1 Citation
    Target: HCV Proteases
    Summary: Inhibitor of HCV NS3/4A protease
      insoluble in H2O; insoluble in EtOH; ≥18.75 mg/mL
  9. Celastrol
    A2604 Celastrol
    Target: Proteasome
    Summary: Antioxidant, anti-inflammatory and immunosuppressive agent
      ≥22.55 mg/mL
  10. SB 239063
    A3792 SB 239063
     1 Citation
    Target: p38
    Summary: P38 MAP kinase inhibitor
      insoluble in H2O; ≥18.4 mg/mL

Items 421-430 of 877

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Category
  1. Proteases 79item
  2. Apoptosis 48item
  3. Chromatin/Epigenetics 106item
  4. Metabolism 64item
  5. MAPK Signaling 46item
  6. Tyrosine Kinase 115item
  7. DNA Damage/DNA Repair 64item
  8. PI3K/Akt/mTOR Signaling 63item
  9. Microbiology & Virology 33item
  10. Cell Cycle/Checkpoint 76item
  11. Ubiquitination/ Proteasome 33item
  12. JAK/STAT Signaling 33item
  13. TGF-β / Smad Signaling 34item
  14. Angiogenesis 9item
  15. GPCR/G protein 42item
  16. Stem Cell 31item
  17. Membrane Transporter/Ion Channel 34item
  18. Endocrinology and Hormones 16item
  19. Neuroscience 35item
  20. Obesity, Appetite Control & Diabetes 2item
  21. Other Signal Transduction 2item
  22. Others 74item
  23. Immunology/Inflammation 17item
  24. Cardiovascular 1 item
Reversibility
  1. Reversible 54item
  2. Irreversible 28item
Target
  1. Caspases 11item
  2. Cyclin-Dependent Kinases 26item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 11item
  5. Cathepsins 11item
  6. Histone Deacetylases (HDACs) 27item
  7. Inhibitor of apoptosis proteins (IAP) 3item
  8. Akt 6item
  9. Bcl-2 6item
  10. PI3K 27item
  11. CXCR 4item
  12. Raf 10item
  13. Aurora Kinases 14item
  14. Bcl-xl 3item
  15. CSF-1R 2item
  16. Glycoproteins 1 item
  17. p97 1 item
  18. Gap Junctions 1 item
  19. MDM2 2item
  20. EZH2 6item
  21. mTOR 15item
  22. Bromodomains 5item
  23. AP-1 3item
  24. MMP 10item
  25. Thymidine Phosphorylases 1 item
  26. Androgen Receptors 4item
  27. Peptidylprolyl isomerases 1 item
  28. Acyl coenzyme A: cholesterol acyltransferases 1 item
  29. Myosin II ATPases 1 item
  30. DT-diaphorases 1 item
  31. MER 1 item
  32. FLT3 12item
  33. GSK-3 9item
  34. Factor Xa 3item
  35. LPA Receptors 1 item
  36. P-glycoprotein (P-gp) 5item
  37. PLK 7item
  38. Chk 8item
  39. ULK1 1 item
  40. Eph Receptors 3item
  41. VEGFR 25item
  42. PDGFR 19item
  43. c-Kit 7item
  44. RET 3item
  45. IRAK 3item
  46. Bromodomain-containing proteins(BRDs) 1 item
  47. Phosphodiesterases (PDEs) 10item
  48. Mcl-1 5item
  49. Hydrolase 1 item
  50. Thymidylate Synthase 2item
  51. p38 9item
  52. PKB 1 item
  53. 3-phosphoglycerate dehydrogenase 1 item
  54. JNK 6item
  55. SGK 2item
  56. Bcr-Abl 10item
  57. Kynurenine-3-monooxygenase 1 item
  58. MEK 15item
  59. PORCN 1 item
  60. DOT1L 3item
  61. FGFR 9item
  62. Nrf2 2item
  63. Insulin-like growth factor receptors(IGFRs) 1 item
  64. CGRP receptors 1 item
  65. Pim 4item
  66. Liver X receptors (LXRs) 1 item
  67. Glucagon-like peptide 1 (GLP-1) receptors 2item
  68. Sir2-like Family Deacetylases (Sirtuins) 2item
  69. Voltage-gated Sodium (NaV) Channels 1 item
  70. Deubiquitinating enzymes (DUBs) 4item
  71. PP1 1 item
  72. PP2A 1 item
  73. Smoothened 4item
  74. Eukaryotic elongation factors 1 item
  75. Ribosomal s6 kinases (RSK) 1 item
  76. Neuraminidases (NA) 1 item
  77. MET 7item
  78. Src 9item
  79. Trk Receptors 6item
  80. Integrins 1 item
  81. Aminopeptidases 2item
  82. STAT 5item
  83. ATP Citrate Lyases 1 item
  84. Microtubules/Tubulins 5item
  85. Estrogen and Related Receptors 1 item
  86. EGFR 15item
  87. Hedgehog 1 item
  88. Reverse Transcriptases 1 item
  89. ROCK 7item
  90. BTK 2item
  91. RIP kinases 1 item
  92. PAK 3item
  93. Hypoxia Inducible Factors (HIFs) 2item
  94. Tankyrases 1 item
  95. Inositol Phosphatases 1 item
  96. FAK 5item
  97. BMP and Other Activin Receptors 4item
  98. JAK 13item
  99. p300 1 item
  100. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  101. Syk 7item
  102. Progesterone Receptors 2item
  103. EZH1 2item
  104. DNA-PK 6item
  105. HSP90 10item
  106. AMPK 3item
  107. Gutathione S-transferase 1 item
  108. CCR 2item
  109. PDHK 1 item
  110. Angiotensin AT2 Receptors 1 item
  111. eIF4E/eIF3G interaction 1 item
  112. Notch 1 item
  113. S-nitrosoglutathione reductase 1 item
  114. CFTR 3item
  115. TNKS 1 item
  116. Topoisomerases 7item
  117. Cytochrome P450 (CYP450) 6item
  118. thrombin 1 item
  119. Ksp 1 item
  120. Ribosomes 1 item
  121. Renin 2item
  122. HIV proteases 1 item
  123. Pepsins 1 item
  124. Influenza viruses 1 item
  125. ErbB 2item
  126. Ferroptosis 1 item
  127. S6 kinases 1 item
  128. Toll-like receptors (TLRs) 3item
  129. Adenosine Kinases 2item
  130. Actin 1 item
  131. DNA Methyltransferases 4item
  132. Survivin 1 item
  133. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  134. ERK 5item
  135. HMG-CoA Reductases 5item
  136. Vacuolar-type ATPase 1 item
  137. c-MET 8item
  138. BMI-1 1 item
  139. PKC 7item
  140. Calpains 5item
  141. Ubiquitin-specific proteases 1 item
  142. HCV Proteases 3item
  143. Ca2 /calmodulin-dependent protein kinases (CaMKs) 8item
  144. MLK3 1 item
  145. SMYD2 1 item
  146. CREBBP 2item
  147. EP300 2item
  148. Protease-Activated Receptors 1 item
  149. Lyn 1 item
  150. SGLT 1 item
  151. RAD51 1 item
  152. Trypsins 1 item
  153. HER2 2item
  154. Pyk2 3item
  155. USP 2item
  156. 5-HT2 Receptors 6item
  157. LRRK2 4item
  158. Calcium chelator 1 item
  159. DGAT 2item
  160. Insulin and Insulin-like Receptors 3item
  161. PARP 4item
  162. CB1 Receptors 1 item
  163. Pyruvate dehydrogenases (PDH) 1 item
  164. ALK 5item
  165. ROS1 2item
  166. Sphingosine kinases (SphKs) 2item
  167. Trypsin 1 item
  168. Chymotrypsin 1 item
  169. Kallikrein 1 item
  170. Trypsinogen 1 item
  171. KRAS G12C 1 item
  172. GTPases 1 item
  173. Monocarboxylate transporters (MCTs) 1 item
  174. CETP 2item
  175. Dehydrogenase 1 item
  176. PKG 1 item
  177. PKA 1 item
  178. Myosin light chain kinases (MLCKs) 2item
  179. GPR30 1 item
  180. BCPCF efflux 1 item
  181. HIV-1 gp120 1 item
  182. D1 and D5 Receptors 1 item
  183. D2 Receptors 4item
  184. D3 Receptors 2item
  185. 5-HT1 Receptors 2item
  186. 5-HT7 Receptors 1 item
  187. CaM-KK 1 item
  188. Valosin-containing protein (VCP) 1 item
  189. AdipoR1 1 item
  190. AdipoR2 1 item
  191. MELK 1 item
  192. Serotonin reuptake 1 item
  193. Insulin-like growth factors (IGFs) 1 item
  194. Clk 1 item
  195. TBK1 1 item
  196. MARK1 1 item
  197. NUAK1 2item
  198. Integrin-ligand interactions 1 item
  199. CSF1R 1 item
  200. Bromodomain and Extra-Terminal motif (BET) 1 item
  201. NUAK2 1 item
  202. Na /H Exchangers (NHEs) 1 item
  203. Lactate Dehydrogenases (LDH) 2item
  204. MK2 3item
  205. Fatty-acid-binding proteins (FABPs) 1 item
  206. 5-HT3 Receptors 1 item
  207. Angiotensin-Converting Enzymes (ACEs) 2item
  208. Tie-2 4item
  209. RSK 2item
  210. p70 S6K 1 item
  211. Free Fatty Acid Receptors 3item
  212. phosphatases 1 item
  213. Autophagy 2item
  214. ATM/ATR 7item
  215. Mixed lineage kinase domain-like protein (MLKL) 1 item
  216. COX 7item
  217. Heparanases 1 item
  218. YAP 1 item
  219. CK1 1 item
  220. IDH2 1 item
  221. Histamine H4 Receptors 2item
  222. CK2 3item
  223. HIPK2 1 item
  224. HIPK3 1 item
  225. HIV Integrases 1 item
  226. Cryptochromes 1 item
  227. G-quadruplexes 1 item
  228. Squalene epoxidases 2item
  229. PRAK 1 item
  230. MAPKAP-K2 1 item
  231. Delayed rectifier outward potassium current (IKr) 1 item
  232. Melatonin Receptors 1 item
  233. 20S proteasomal chymotrypsin 1 item
  234. Geranylgeranyltransferase I 1 item
  235. Farnesyltransferase 1 item
  236. NAT10 1 item
  237. Nampt 2item
  238. eIF4F 1 item
  239. Cdc42 1 item
  240. SRPK1 1 item
  241. P2X Receptors 2item
  242. Glutaminases 1 item
  243. Carbonic Anhydrases 5item
  244. Ron 1 item
  245. AP endonucleases 1 item
  246. G9a 2item
  247. BLM 1 item
  248. HSV 2item
  249. NADPH Oxidases 2item
  250. Calcium-activated chloride channels (CaCC) 1 item
  251. GPR35 1 item
  252. Aldehyde Dehydrogenases 2item
  253. Synthases/Synthetases 3item
  254. MAGL 1 item
  255. NPY Receptors 1 item
  256. c-Fyn 1 item
  257. Leukotriene and Related Receptors 1 item
  258. TAK1 1 item
  259. Histamine H1 Receptors 3item
  260. Na /K ATPases 2item
  261. P110 1 item
  262. Hck 1 item
  263. Inositol-requiring enzyme 1 (IRE1) 1 item
  264. SETD7 1 item
  265. Na /K /Cl- Symporters (NKCCs) 1 item
  266. GABAA Receptors 1 item
  267. iNOS 1 item
  268. Histamine H2 Receptors 1 item
  269. Phospholipases 1 item
  270. TRP Channel 2item
  271. RNA Polymerases 2item
  272. Norepinephrine transporter 1 item
  273. 5-HT Transporters 3item
  274. Xanthine oxidoreductases 1 item
  275. Dihydroorotate dehydrogenase 1 item
  276. Guanylyl Cyclases 1 item
  277. Histone Demethylases 1 item
  278. Apoptosis Inducers 1 item
  279. MNK 1 item
  280. NO Donors / Precursors 1 item
  281. CB2 Receptors 1 item
  282. Glucocorticoid Receptors 1 item
  283. HIV-1 reverse transcriptase 1 item
  284. IL Receptors 2item
  285. CCL2 1 item
  286. Norepinephrine transporters 1 item
  287. 15-lipoxygenases 1 item
  288. Calcium-Activated Potassium (KCa) Channels 1 item
  289. AChE 2item
  290. Insulin Receptors 1 item
  291. IRG-1R 1 item
  292. Proton Pump 1 item
  293. cAMP 1 item
  294. Sulfonylurea receptors 1 item
  295. eEF-2 1 item
  296. Inward Rectifier Potassium (Kir) Channels 3item
  297. Arp2/3 complex 1 item
  298. CRTH2 1 item
  299. Cdc7 1 item
  300. Nuclear Receptors 1 item
  301. CMV 1 item
  302. ZAP-70 1 item
  303. Catechol O-Methyltransferase (COMT) 2item
  304. fibrinolysis 1 item
  305. Angiotensin AT1 Receptors 2item
  306. D4 Receptors 1 item
  307. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  308. HBV Proteases 1 item
  309. Flk-1 1 item
  310. Adenine receptors 1 item
  311. Papains 1 item
  312. Protein Arginine Methyltransferases 1 item
  313. IMPDH 1 item
  314. Na /Ca2 Exchangers (NCXs) 1 item
  315. NAE 2item
  316. Ubiquitin-activating Enzyme E1 1 item
  317. SUMOylation 1 item
  318. ATGL 1 item
  319. BACE 1 item
  320. Cytidine deaminases 1 item
  321. angiogenesis 1 item
  322. Glucagon Receptors 1 item
  323. 15-PGDH 1 item
  324. DPP-4 4item
  325. PP4 1 item
  326. c-RET 1 item
  327. Nonstructural protein 5B (NS5B) 1 item
  328. ETA Receptors 2item
  329. ETB Receptors 1 item
  330. p70 rsk 1 item
  331. FPTase 1 item
  332. ADAMs 1 item
  333. TAM kinase 1 item
  334. p53-MDM2 interaction 1 item
  335. nuclear export 1 item
  336. CRM1 1 item
  337. AXL 1 item
  338. Protein polybromo-1 1 item
  339. SMARCA4 1 item
  340. SMARCA2 1 item
  341. Dipeptidyl-peptidase II 1 item
  342. HDAC 1 item
  343. c-Fms tyrosine kinase 1 item
  344. human lyase 1 item
  345. Ub-conjugating enzyme (E2) complex 1 item
  346. STK 1 item
  347. IKK 1 item
  348. MSK 1 item
  349. HCV polymerase 2item
  350. Ftase 1 item
  351. PC-PLC 1 item
  352. Elastases 1 item
  353. P97 ATPase 1 item
  354. NTPDases 1 item
  355. Rev-Erb Receptors 1 item
  356. telomerase 1 item
  357. Histone Acetyltransferases (HATs) 1 item
  358. F1 Fo-ATPase 1 item
  359. ITK 1 item
  360. NOD1 1 item
  361. NUAK 1 item
  362. DCLK2 1 item
  363. FAAH 1 item
  364. TYK2 1 item
  365. Lck 1 item
  366. NOP Receptors 1 item
  367. Aromatases 1 item
  368. PKD 1 item
  369. SHIP 1 item
  370. MCL1 1 item
  371. Bcl-w 1 item
  372. tropomyosin receptor kinase 1 item
  373. LSD 1 item
  374. PRMT 1 item
  375. GLP 1 item
  376. SK 1 item
  377. MST 1 item
  378. IDO 1 item
  379. Serotonin (5-HT) reuptake 1 item
  380. Androgen Receptor 1 item
  381. Substance P/NK1 Receptor 1 item
  382. gp120/CD4 1 item
  383. ATM 2item
  384. Sirtuin 1 item
  385. NE 1 item
  386. CRF1 Receptors 1 item
  387. PIKfyve 1 item
  388. Glycogen Phosphorylases 1 item
  389. MTH1 1 item
  390. Insulin Receptor 1 item
Reported Experiments
  1. Animal Experiments 749item
  2. Cell Experiments 510item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acne 1 item
  3. Acute Disseminated Candidiasis 1 item
  4. Acute Kidney Injury 1 item
  5. Acute Lung Injury 1 item
  6. Acute Myelogenous Leukemia 6item
  7. Acute Myeloid Leukemia 28item
  8. Acute Renal Failure 1 item
  9. Adrenocortical Carcinoma 4item
  10. Advanced Renal Cell Carcinoma 1 item
  11. Autoimmune Diseases 1 item
  12. Biliary Cancer 1 item
  13. Bladder Cancer 10item
  14. Bladder Carcinoma 4item
  15. Bladder Diseases 2item
  16. B-lymphoid Malignancies 1 item
  17. Brain Injuries Studies 3item
  18. Breast Cancer 122item
  19. Cancer 455item
  20. Candida Peritonitis 1 item
  21. Candidemia 1 item
  22. Castration-resistant Prostate Cancer 1 item
  23. Cervical Cancer 5item
  24. Cholangiocarcinoma 2item
  25. Chronic Lymphocytic Leukemia 8item
  26. Chronic Myeloproliferative Disorders 1 item
  27. Clear Cell Renal Cell Carcinoma 2item
  28. Cocaine-Related Disorders 2item
  29. Colon Cancer 46item
  30. Colon Carcinoma 7item
  31. Colorectal Cancer 42item
  32. Depression 2item
  33. Diabetes 9item
  34. Diffuse Large B-cell Lymphoma 1 item
  35. Dyskinesia 1 item
  36. Dyslipidemia 2item
  37. Epilepsy 2item
  38. Erectile Dysfunction 3item
  39. Friedreich's Ataxia 1 item
  40. Fungal Infection 1 item
  41. Glioblastoma 35item
  42. Glioma 19item
  43. HCV 3item
  44. Heart Failure 1 item
  45. Hepatic Cancer 2item
  46. Hepatitis C 3item
  47. Hepatocellular Carcinoma 8item
  48. HIV 5item
  49. HIV Infections 12item
  50. Hypercholesterolemia 2item
  51. Immunological Diseases 1 item
  52. Inflammation 1 item
  53. Inflammatory Bowel Disease 1 item
  54. Inflammatory Diseases 17item
  55. Influenza 2item
  56. Kidney Injury Studies 1 item
  57. Leukemia 24item
  58. Liver Cancer 3item
  59. Lung Cancer 44item
  60. Lung Carcinoma 4item
  61. Lymphoma 32item
  62. Mantle Cell Lymphoma 2item
  63. Medulloblastoma 1 item
  64. Melanoma 38item
  65. Mixed Lineage Leukemia 3item
  66. Multiple Myeloma 23item
  67. Myelofibrosis 2item
  68. Myeloma 8item
  69. Narcolepsy 1 item
  70. Neuroblastoma 14item
  71. Neurocognitive Disorders 1 item
  72. Neuronal Protection 1 item
  73. Non-small Cell Lung Cancer 27item
  74. Non-small Cell Lung Carcinoma 2item
  75. Obsessive-Compulsive Disorder 1 item
  76. Osteoporosis 2item
  77. Ovarian Cancer 35item
  78. Pancreatic Cancer 48item
  79. Pancreatic Carcinoma 3item
  80. Prostate Cancer 60item
  81. Psoriasis 4item
  82. Psoriasis Vulgaris 1 item
  83. Pulmonary Arterial Hypertension 2item
  84. Pulmonary Fibrosis 2item
  85. Renal Cancer 4item
  86. Renal Cell Carcinoma 9item
  87. Rheumatoid Arthritis 14item
  88. Sarcoma 1 item
  89. Schizophrenia 8item
  90. Sleep Disorders 1 item
  91. Soft Tissue Sarcoma 1 item
  92. Squamous Cell Carcinoma 2item
  93. Testicular Cancer 2item
  94. Thyroid Cancer 6item
  95. Tuberculosis 1 item
  96. Type 2 Diabetes 17item