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  • Search results for: 'gsk 3 inhibitor 1'

Search results for: 'gsk 3 inhibitor 1'

Items 1-10 of 749

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  1. CHIR-99021 (CT99021)
    A3011 CHIR-99021 (CT99021)
     2 Citation
    Target: GSK-3
    Summary: GSK-3 inhibitor, Cell-permeable, ATP-competitive
      ≥23.27 mg/mL
  2. Dabrafenib Mesylate (GSK-2118436)
    A3347 Dabrafenib Mesylate (GSK-2118436)
    Target: Raf
    Summary: Inhibitor of BRAF(V600) mutants
      ≥30.75 mg/mL
  3. Torin 1
    A8312 Torin 1
     7 Citation
    Target: mTOR
    Summary: MTOR inhibitor,potent and selective
  4. AR-A014418
    A3184 AR-A014418
     2 Citation
    Target: GSK-3
    Summary: GSK3β inhibitor, ATP-competitive and selective
      insoluble in EtOH; insoluble in H2O; ≥15.4 mg/mL
  5. GSK126
    A3446 GSK126
     5 Citation
    Target: EZH2
    Summary: EZH2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥4.38 mg/mL
  6. GSK 4112
    B7460 GSK 4112
    Target: Rev-Erb Receptors
    Summary: Rev-Erbα agonist
      insoluble in EtOH; insoluble in H2O; ≥11.9 mg/mL
  7. 3-Methyladenine
    A8353 3-Methyladenine
     3 Citation
    Target: PI3K
    Summary: Class III PI3K inhibitor
      ≥5 mg/mL
  8. PP 1
    A8215 PP 1
    Target: Src|EGFR|JAK|ZAP-70
    Summary: Src family tyrosine kinase inhibitor
  9. IKK-2 inhibitor VIII
    A3485 IKK-2 inhibitor VIII
    Summary: IKK-2 inhibitor,potent and selective
      Soluble in DMSO
  10. Nutlin-3
    A4228 Nutlin-3
    Target: MDM2
    Summary: MDM2 antagonist,inhibits MDM2-p53 interaction
      ≥58.2 mg/mL

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Category
  1. Proteases 69item
  2. Apoptosis 38item
  3. Chromatin/Epigenetics 86item
  4. Metabolism 60item
  5. MAPK Signaling 41item
  6. Tyrosine Kinase 103item
  7. DNA Damage/DNA Repair 55item
  8. PI3K/Akt/mTOR Signaling 58item
  9. Microbiology & Virology 30item
  10. Cell Cycle/Checkpoint 58item
  11. Ubiquitination/ Proteasome 24item
  12. JAK/STAT Signaling 30item
  13. TGF-β / Smad Signaling 28item
  14. Angiogenesis 6item
  15. GPCR/G protein 40item
  16. Stem Cell 26item
  17. Membrane Transporter/Ion Channel 26item
  18. Endocrinology and Hormones 15item
  19. Neuroscience 33item
  20. Obesity, Appetite Control & Diabetes 2item
  21. Other Signal Transduction 1 item
  22. Others 63item
  23. Immunology/Inflammation 11item
  24. Cardiovascular 1 item
Reversibility
  1. Reversible 45item
  2. Irreversible 20item
Target
  1. Caspases 7item
  2. Cyclin-Dependent Kinases 20item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 11item
  5. Cathepsins 9item
  6. Histone Deacetylases (HDACs) 23item
  7. Inhibitor of apoptosis proteins (IAP) 3item
  8. Akt 6item
  9. Bcl-2 6item
  10. PI3K 26item
  11. CXCR 4item
  12. Raf 10item
  13. Aurora Kinases 11item
  14. Bcl-xl 2item
  15. CSF-1R 2item
  16. Glycoproteins 1 item
  17. p97 1 item
  18. MDM2 2item
  19. EZH2 4item
  20. mTOR 14item
  21. Bromodomains 4item
  22. AP-1 3item
  23. MMP 8item
  24. Thymidine Phosphorylases 1 item
  25. Androgen Receptors 4item
  26. Peptidylprolyl isomerases 1 item
  27. Acyl coenzyme A: cholesterol acyltransferases 1 item
  28. Myosin II ATPases 1 item
  29. DT-diaphorases 1 item
  30. MER 1 item
  31. FLT3 12item
  32. GSK-3 9item
  33. Factor Xa 3item
  34. LPA Receptors 1 item
  35. P-glycoprotein (P-gp) 5item
  36. PLK 6item
  37. Chk 7item
  38. Eph Receptors 2item
  39. VEGFR 25item
  40. PDGFR 17item
  41. c-Kit 7item
  42. RET 3item
  43. Bromodomain-containing proteins(BRDs) 1 item
  44. Phosphodiesterases (PDEs) 10item
  45. Mcl-1 4item
  46. Hydrolase 1 item
  47. Thymidylate Synthase 2item
  48. p38 9item
  49. PKB 1 item
  50. JNK 3item
  51. SGK 1 item
  52. Bcr-Abl 8item
  53. Kynurenine-3-monooxygenase 1 item
  54. MEK 13item
  55. PORCN 1 item
  56. DOT1L 3item
  57. FGFR 9item
  58. Nrf2 2item
  59. Insulin-like growth factor receptors(IGFRs) 1 item
  60. CGRP receptors 1 item
  61. Pim 3item
  62. Liver X receptors (LXRs) 1 item
  63. Glucagon-like peptide 1 (GLP-1) receptors 2item
  64. Sir2-like Family Deacetylases (Sirtuins) 2item
  65. Voltage-gated Sodium (NaV) Channels 1 item
  66. Deubiquitinating enzymes (DUBs) 3item
  67. PP1 1 item
  68. PP2A 1 item
  69. Smoothened 4item
  70. Eukaryotic elongation factors 1 item
  71. Neuraminidases (NA) 1 item
  72. MET 7item
  73. Src 5item
  74. Trk Receptors 6item
  75. Integrins 1 item
  76. Aminopeptidases 2item
  77. STAT 5item
  78. ATP Citrate Lyases 1 item
  79. Microtubules/Tubulins 4item
  80. Estrogen and Related Receptors 1 item
  81. EGFR 14item
  82. Hedgehog 1 item
  83. ROCK 5item
  84. BTK 1 item
  85. RIP kinases 1 item
  86. PAK 3item
  87. Hypoxia Inducible Factors (HIFs) 2item
  88. Tankyrases 1 item
  89. Inositol Phosphatases 1 item
  90. FAK 5item
  91. BMP and Other Activin Receptors 3item
  92. JAK 12item
  93. p300 1 item
  94. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  95. Syk 7item
  96. Progesterone Receptors 2item
  97. EZH1 2item
  98. DNA-PK 6item
  99. HSP90 10item
  100. AMPK 3item
  101. Gutathione S-transferase 1 item
  102. CCR 2item
  103. PDHK 1 item
  104. Angiotensin AT2 Receptors 1 item
  105. Notch 1 item
  106. S-nitrosoglutathione reductase 1 item
  107. CFTR 3item
  108. TNKS 1 item
  109. Topoisomerases 6item
  110. Cytochrome P450 (CYP450) 6item
  111. thrombin 1 item
  112. Ksp 1 item
  113. Renin 1 item
  114. Influenza viruses 1 item
  115. ErbB 2item
  116. S6 kinases 1 item
  117. Toll-like receptors (TLRs) 2item
  118. Adenosine Kinases 2item
  119. DNA Methyltransferases 3item
  120. Survivin 1 item
  121. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  122. ERK 5item
  123. HMG-CoA Reductases 5item
  124. c-MET 8item
  125. BMI-1 1 item
  126. PKC 6item
  127. Calpains 5item
  128. Ubiquitin-specific proteases 1 item
  129. HCV Proteases 3item
  130. Ca2 /calmodulin-dependent protein kinases (CaMKs) 7item
  131. MLK3 1 item
  132. CREBBP 1 item
  133. EP300 1 item
  134. Protease-Activated Receptors 1 item
  135. Lyn 1 item
  136. SGLT 1 item
  137. RAD51 1 item
  138. Trypsins 1 item
  139. HER2 2item
  140. Pyk2 3item
  141. 5-HT2 Receptors 6item
  142. LRRK2 4item
  143. Calcium chelator 1 item
  144. DGAT 2item
  145. Insulin and Insulin-like Receptors 3item
  146. PARP 3item
  147. CB1 Receptors 1 item
  148. Pyruvate dehydrogenases (PDH) 1 item
  149. ALK 5item
  150. ROS1 2item
  151. Sphingosine kinases (SphKs) 2item
  152. Trypsin 1 item
  153. Chymotrypsin 1 item
  154. Kallikrein 1 item
  155. Trypsinogen 1 item
  156. Monocarboxylate transporters (MCTs) 1 item
  157. CETP 2item
  158. Dehydrogenase 1 item
  159. Myosin light chain kinases (MLCKs) 1 item
  160. GPR30 1 item
  161. BCPCF efflux 1 item
  162. HIV-1 gp120 1 item
  163. D1 and D5 Receptors 1 item
  164. D2 Receptors 4item
  165. D3 Receptors 2item
  166. 5-HT1 Receptors 2item
  167. 5-HT7 Receptors 1 item
  168. AdipoR1 1 item
  169. AdipoR2 1 item
  170. MELK 1 item
  171. Serotonin reuptake 1 item
  172. Insulin-like growth factors (IGFs) 1 item
  173. CSF1R 1 item
  174. Bromodomain and Extra-Terminal motif (BET) 1 item
  175. Lactate Dehydrogenases (LDH) 1 item
  176. MK2 2item
  177. Fatty-acid-binding proteins (FABPs) 1 item
  178. 5-HT3 Receptors 1 item
  179. Angiotensin-Converting Enzymes (ACEs) 2item
  180. Tie-2 4item
  181. RSK 2item
  182. p70 S6K 1 item
  183. Free Fatty Acid Receptors 2item
  184. phosphatases 1 item
  185. Autophagy 2item
  186. ATM/ATR 5item
  187. COX 6item
  188. YAP 1 item
  189. Histamine H4 Receptors 2item
  190. CK2 2item
  191. HIPK2 1 item
  192. HIPK3 1 item
  193. Squalene epoxidases 2item
  194. PRAK 1 item
  195. MAPKAP-K2 1 item
  196. Delayed rectifier outward potassium current (IKr) 1 item
  197. 20S proteasomal chymotrypsin 1 item
  198. Geranylgeranyltransferase I 1 item
  199. Farnesyltransferase 1 item
  200. Nampt 2item
  201. eIF4F 1 item
  202. Cdc42 1 item
  203. SRPK1 1 item
  204. P2X Receptors 2item
  205. Glutaminases 1 item
  206. Carbonic Anhydrases 5item
  207. Ron 1 item
  208. G9a 1 item
  209. BLM 1 item
  210. HSV 1 item
  211. NADPH Oxidases 2item
  212. Calcium-activated chloride channels (CaCC) 1 item
  213. GPR35 1 item
  214. Aldehyde Dehydrogenases 2item
  215. Synthases/Synthetases 2item
  216. MAGL 1 item
  217. NPY Receptors 1 item
  218. Leukotriene and Related Receptors 1 item
  219. Histamine H1 Receptors 3item
  220. Na /K ATPases 2item
  221. P110 1 item
  222. Hck 1 item
  223. Inositol-requiring enzyme 1 (IRE1) 1 item
  224. Na /K /Cl- Symporters (NKCCs) 1 item
  225. GABAA Receptors 1 item
  226. Histamine H2 Receptors 1 item
  227. Phospholipases 1 item
  228. TRP Channel 2item
  229. RNA Polymerases 2item
  230. Norepinephrine transporter 1 item
  231. 5-HT Transporters 3item
  232. Xanthine oxidoreductases 1 item
  233. Dihydroorotate dehydrogenase 1 item
  234. Guanylyl Cyclases 1 item
  235. Histone Demethylases 1 item
  236. MNK 1 item
  237. NO Donors / Precursors 1 item
  238. CB2 Receptors 1 item
  239. Glucocorticoid Receptors 1 item
  240. HIV-1 reverse transcriptase 1 item
  241. IL Receptors 2item
  242. CCL2 1 item
  243. Norepinephrine transporters 1 item
  244. 15-lipoxygenases 1 item
  245. Calcium-Activated Potassium (KCa) Channels 1 item
  246. AChE 2item
  247. Insulin Receptors 1 item
  248. IRG-1R 1 item
  249. cAMP 1 item
  250. Sulfonylurea receptors 1 item
  251. eEF-2 1 item
  252. Inward Rectifier Potassium (Kir) Channels 2item
  253. CRTH2 1 item
  254. Cdc7 1 item
  255. Nuclear Receptors 1 item
  256. CMV 1 item
  257. ZAP-70 1 item
  258. Catechol O-Methyltransferase (COMT) 2item
  259. fibrinolysis 1 item
  260. Angiotensin AT1 Receptors 2item
  261. D4 Receptors 1 item
  262. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  263. HBV Proteases 1 item
  264. Flk-1 1 item
  265. Adenine receptors 1 item
  266. Papains 1 item
  267. Protein Arginine Methyltransferases 1 item
  268. IMPDH 1 item
  269. Na /Ca2 Exchangers (NCXs) 1 item
  270. NAE 2item
  271. Ubiquitin-activating Enzyme E1 1 item
  272. SUMOylation 1 item
  273. ATGL 1 item
  274. BACE 1 item
  275. Cytidine deaminases 1 item
  276. angiogenesis 1 item
  277. Glucagon Receptors 1 item
  278. 15-PGDH 1 item
  279. DPP-4 4item
  280. PP4 1 item
  281. c-RET 1 item
  282. Nonstructural protein 5B (NS5B) 1 item
  283. ETA Receptors 2item
  284. ETB Receptors 1 item
  285. p70 rsk 1 item
  286. FPTase 1 item
  287. ADAMs 1 item
  288. TAM kinase 1 item
  289. p53-MDM2 interaction 1 item
  290. nuclear export 1 item
  291. CRM1 1 item
  292. AXL 1 item
  293. Dipeptidyl-peptidase II 1 item
  294. HDAC 1 item
  295. c-Fms tyrosine kinase 1 item
  296. human lyase 1 item
  297. Ub-conjugating enzyme (E2) complex 1 item
  298. IKK 1 item
  299. MSK 1 item
  300. HCV polymerase 1 item
  301. Ftase 1 item
  302. PC-PLC 1 item
  303. Elastases 1 item
  304. Rev-Erb Receptors 1 item
  305. F1 Fo-ATPase 1 item
  306. ITK 1 item
  307. NUAK 1 item
  308. DCLK2 1 item
  309. FAAH 1 item
  310. TYK2 1 item
  311. NOP Receptors 1 item
  312. Aromatases 1 item
  313. PKD 1 item
  314. SHIP 1 item
  315. MCL1 1 item
  316. Bcl-w 1 item
  317. tropomyosin receptor kinase 1 item
  318. LSD 1 item
  319. PRMT 1 item
  320. GLP 1 item
  321. SK 1 item
  322. MST 1 item
  323. IDO 1 item
  324. Serotonin (5-HT) reuptake 1 item
  325. Androgen Receptor 1 item
  326. Substance P/NK1 Receptor 1 item
  327. gp120/CD4 1 item
  328. ATM 1 item
  329. Sirtuin 1 item
  330. NE 1 item
  331. CRF1 Receptors 1 item
  332. PIKfyve 1 item
  333. Glycogen Phosphorylases 1 item
  334. MTH1 1 item
  335. Insulin Receptor 1 item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acne 1 item
  3. Acute Disseminated Candidiasis 1 item
  4. Acute Kidney Injury 1 item
  5. Acute Lung Injury 1 item
  6. Acute Myelogenous Leukemia 5item
  7. Acute Myeloid Leukemia 27item
  8. Acute Renal Failure 1 item
  9. Adrenocortical Carcinoma 4item
  10. Advanced Renal Cell Carcinoma 1 item
  11. Autoimmune Diseases 1 item
  12. Biliary Cancer 1 item
  13. Bladder Cancer 10item
  14. Bladder Carcinoma 4item
  15. Bladder Diseases 2item
  16. B-lymphoid Malignancies 1 item
  17. Brain Injuries Studies 3item
  18. Breast Cancer 114item
  19. Cancer 412item
  20. Candida Peritonitis 1 item
  21. Candidemia 1 item
  22. Castration-resistant Prostate Cancer 1 item
  23. Cervical Cancer 5item
  24. Cholangiocarcinoma 2item
  25. Chronic Lymphocytic Leukemia 8item
  26. Chronic Myeloproliferative Disorders 1 item
  27. Clear Cell Renal Cell Carcinoma 2item
  28. Cocaine-Related Disorders 2item
  29. Colon Cancer 39item
  30. Colon Carcinoma 7item
  31. Colorectal Cancer 40item
  32. Depression 2item
  33. Diabetes 7item
  34. Diffuse Large B-cell Lymphoma 1 item
  35. Dyskinesia 1 item
  36. Dyslipidemia 2item
  37. Epilepsy 2item
  38. Erectile Dysfunction 3item
  39. Friedreich's Ataxia 1 item
  40. Fungal Infection 1 item
  41. Glioblastoma 33item
  42. Glioma 18item
  43. HCV 2item
  44. Heart Failure 1 item
  45. Hepatic Cancer 2item
  46. Hepatitis C 3item
  47. Hepatocellular Carcinoma 8item
  48. HIV 4item
  49. HIV Infections 11item
  50. Hypercholesterolemia 2item
  51. Immunological Diseases 1 item
  52. Inflammation 1 item
  53. Inflammatory Bowel Disease 1 item
  54. Inflammatory Diseases 16item
  55. Influenza 2item
  56. Kidney Injury Studies 1 item
  57. Leukemia 23item
  58. Liver Cancer 3item
  59. Lung Cancer 39item
  60. Lung Carcinoma 4item
  61. Lymphoma 28item
  62. Mantle Cell Lymphoma 2item
  63. Medulloblastoma 1 item
  64. Melanoma 34item
  65. Mixed Lineage Leukemia 3item
  66. Multiple Myeloma 21item
  67. Myelofibrosis 2item
  68. Myeloma 8item
  69. Narcolepsy 1 item
  70. Neuroblastoma 14item
  71. Neurocognitive Disorders 1 item
  72. Neuronal Protection 1 item
  73. Non-small Cell Lung Cancer 26item
  74. Non-small Cell Lung Carcinoma 2item
  75. Obsessive-Compulsive Disorder 1 item
  76. Osteoporosis 2item
  77. Ovarian Cancer 33item
  78. Pancreatic Cancer 47item
  79. Pancreatic Carcinoma 3item
  80. Prostate Cancer 55item
  81. Psoriasis 4item
  82. Psoriasis Vulgaris 1 item
  83. Pulmonary Arterial Hypertension 2item
  84. Pulmonary Fibrosis 2item
  85. Renal Cancer 4item
  86. Renal Cell Carcinoma 9item
  87. Rheumatoid Arthritis 14item
  88. Sarcoma 1 item
  89. Schizophrenia 8item
  90. Sleep Disorders 1 item
  91. Soft Tissue Sarcoma 1 item
  92. Squamous Cell Carcinoma 2item
  93. Testicular Cancer 2item
  94. Thyroid Cancer 6item
  95. Tuberculosis 1 item
  96. Type 2 Diabetes 16item