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  • Search results for: 'gsk 3 inhibitor 1'

Search results for: 'gsk 3 inhibitor 1'

Items 231-240 of 583

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  1. GDC-0449 (Vismodegib)
    A3021 GDC-0449 (Vismodegib)
     1 Citation
    Target: P-glycoprotein (P-gp)|Hedgehog
    Summary: Hedgehog antagonist,potent and selective
      ≥21.08 mg/mL
  2. LY 294002
    A8250 LY 294002
     16 Citation
    Target: PI3K
    Summary: Potent PI3K inhibitor
  3. Cyclopamine
    A8340 Cyclopamine
     1 Citation
    Target: Smoothened
    Summary: Hedgehog (Hh) signaling Inhibitor
      insoluble in EtOH; insoluble in H2O; ≥6.86 mg/mL
  4. LY2784544
    A4147 LY2784544
    Target: Aurora Kinases|FLT3|VEGFR|FGFR|Trk Receptors|JAK|ALK|TYK2|MUSK|MAP3K
    Summary: JAK2 inhibitor,highly potent and selective
      ≥23.5 mg/mL
  5. BMS-911543
    A4152 BMS-911543
    Target: JAK
    Summary: JAK2 inhibitor,selective small molecule
      ≥43.3 mg/mL
  6. Silvestrol
    A3818 Silvestrol
    Summary: Antineoplastic
      Soluble in DMSO
  7. THZ1 Hydrochloride
    B4736 THZ1 Hydrochloride
    Target: Cyclin-Dependent Kinases
    Summary: CDK7 inhibitor
      ≥30.13 mg/mL
  8. NH125
    A8814 NH125
     1 Citation
    Target: eEF-2
    Summary: Selective eEF-2 kinase inhibitor
      ≥25.9 mg/mL
  9. Midostaurin (PKC412)
    B3709 Midostaurin (PKC412)
    Target: PKC|PKA|KDR|Flk1|PPK|c-Syk|CDK1/CyclinB
    Summary: PKC inhibitor
      ≥57.1 mg/mL
  10. GSK2636771
    B2186 GSK2636771
    Target: PI3K
    Summary: PIK3 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥10.83 mg/mL

Items 231-240 of 583

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Category
  1. Signaling Pathways 568item
  2. Natural Products 4item
  3. Probes & Dyes 1 item
  4. Cell Biology 1 item
  5. Lab Reagents 1 item
Specificity
  1. Selective 466item
  2. Non-Selective 2item
Reversibility
  1. Reversible 28item
  2. Irreversible 22item
Target
  1. Caspases 4item
  2. Cyclin-Dependent Kinases 25item
  3. Proteasome 9item
  4. Cathepsins 2item
  5. Histone Deacetylases (HDACs) 25item
  6. Inhibitor of apoptosis proteins (IAP) 2item
  7. Akt 11item
  8. Bcl-2 8item
  9. PI3K 26item
  10. CXCR 2item
  11. Raf 11item
  12. Aurora Kinases 18item
  13. Bcl-xl 2item
  14. CSF-1R 4item
  15. Glycoproteins 1 item
  16. p97 1 item
  17. MDM2 2item
  18. EZH2 5item
  19. mTOR 15item
  20. Bromodomains 5item
  21. AP-1 1 item
  22. MMP 3item
  23. Thymidine Phosphorylases 1 item
  24. Androgen Receptors 4item
  25. DT-diaphorases 1 item
  26. FLT3 12item
  27. GSK-3 5item
  28. LPA Receptors 1 item
  29. P-glycoprotein (P-gp) 5item
  30. PLK 9item
  31. Chk 5item
  32. ULK1 1 item
  33. Eph Receptors 3item
  34. VEGFR 36item
  35. PDGFR 21item
  36. c-Kit 10item
  37. RET 4item
  38. Bromodomain-containing proteins(BRDs) 1 item
  39. Phosphodiesterases (PDEs) 3item
  40. Mcl-1 5item
  41. Thymidylate Synthase 3item
  42. p38 3item
  43. 3-phosphoglycerate dehydrogenase 1 item
  44. JNK 1 item
  45. SGK 2item
  46. Bcr-Abl 8item
  47. MEK 11item
  48. PORCN 1 item
  49. DOT1L 3item
  50. FGFR 13item
  51. Nrf2 1 item
  52. Insulin-like growth factor receptors(IGFRs) 1 item
  53. Pim 4item
  54. Liver X receptors (LXRs) 1 item
  55. Sir2-like Family Deacetylases (Sirtuins) 2item
  56. Deubiquitinating enzymes (DUBs) 4item
  57. PP1 1 item
  58. PP2A 1 item
  59. Smoothened 4item
  60. Ribosomal s6 kinases (RSK) 1 item
  61. MET 7item
  62. Src 9item
  63. Trk Receptors 5item
  64. Integrins 1 item
  65. Aminopeptidases 2item
  66. STAT 9item
  67. Microtubules/Tubulins 6item
  68. Estrogen and Related Receptors 2item
  69. EGFR 20item
  70. Hedgehog 1 item
  71. ROCK 1 item
  72. PAK 3item
  73. Hypoxia Inducible Factors (HIFs) 2item
  74. FAK 7item
  75. BMP and Other Activin Receptors 2item
  76. JAK 12item
  77. p300 1 item
  78. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  79. Syk 4item
  80. Progesterone Receptors 1 item
  81. EZH1 1 item
  82. DNA-PK 5item
  83. HSP90 12item
  84. AMPK 1 item
  85. Gutathione S-transferase 1 item
  86. CCR 1 item
  87. eIF4E/eIF3G interaction 1 item
  88. Notch 1 item
  89. TNKS 1 item
  90. Topoisomerases 11item
  91. Cytochrome P450 (CYP450) 4item
  92. Ksp 1 item
  93. ErbB 5item
  94. Actin 1 item
  95. DNA Methyltransferases 3item
  96. Survivin 1 item
  97. ERK 4item
  98. HMG-CoA Reductases 2item
  99. Vacuolar-type ATPase 1 item
  100. c-MET 7item
  101. BMI-1 1 item
  102. PKC 11item
  103. Calpains 2item
  104. Ubiquitin-specific proteases 1 item
  105. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  106. SMYD2 1 item
  107. CREBBP 1 item
  108. EP300 1 item
  109. Lyn 1 item
  110. RAD51 2item
  111. HER2 2item
  112. Pyk2 3item
  113. USP 1 item
  114. 5-HT2 Receptors 2item
  115. Calcium chelator 1 item
  116. Insulin and Insulin-like Receptors 2item
  117. PARP 3item
  118. Pyruvate dehydrogenases (PDH) 1 item
  119. ALK 8item
  120. ROS1 2item
  121. Sphingosine kinases (SphKs) 2item
  122. KRAS G12C 1 item
  123. Monocarboxylate transporters (MCTs) 1 item
  124. Dehydrogenase 1 item
  125. PKG 2item
  126. PKA 5item
  127. Myosin light chain kinases (MLCKs) 1 item
  128. GPR30 1 item
  129. D1 and D5 Receptors 1 item
  130. D2 Receptors 2item
  131. D3 Receptors 1 item
  132. Valosin-containing protein (VCP) 1 item
  133. MELK 1 item
  134. Insulin-like growth factors (IGFs) 1 item
  135. Integrin-ligand interactions 1 item
  136. CSF1R 1 item
  137. Bromodomain and Extra-Terminal motif (BET) 1 item
  138. MK2 2item
  139. 5-HT3 Receptors 1 item
  140. Angiotensin-Converting Enzymes (ACEs) 1 item
  141. Tie-2 4item
  142. RSK 2item
  143. p70 S6K 1 item
  144. Autophagy 3item
  145. ATM/ATR 6item
  146. COX 3item
  147. Heparanases 1 item
  148. YAP 1 item
  149. CK1 1 item
  150. IDH2 1 item
  151. CK2 2item
  152. HIPK2 1 item
  153. HIPK3 1 item
  154. HIV Integrases 1 item
  155. Pregnane X Receptors 1 item
  156. G-quadruplexes 1 item
  157. PRAK 1 item
  158. MAPKAP-K2 1 item
  159. Guanine nucleotide exchange factors (GEFs) 1 item
  160. 20S proteasomal chymotrypsin 1 item
  161. Geranylgeranyltransferase I 1 item
  162. Farnesyltransferase 1 item
  163. Nampt 3item
  164. eIF4F 1 item
  165. Cdc42 1 item
  166. P2X Receptors 1 item
  167. Glutaminases 2item
  168. Carbonic Anhydrases 1 item
  169. Ron 1 item
  170. BLM 1 item
  171. Aldehyde Dehydrogenases 1 item
  172. Synthases/Synthetases 2item
  173. MAGL 1 item
  174. P110 1 item
  175. Hck 1 item
  176. Inositol-requiring enzyme 1 (IRE1) 1 item
  177. iNOS 1 item
  178. Histamine H2 Receptors 1 item
  179. RNA Polymerases 1 item
  180. DYRK 1 item
  181. Norepinephrine transporter 1 item
  182. 5-HT Transporters 1 item
  183. Guanylyl Cyclases 1 item
  184. Histone Demethylases 2item
  185. Apoptosis Inducers 1 item
  186. MNK 1 item
  187. Glucocorticoid Receptors 1 item
  188. HIV-1 reverse transcriptase 1 item
  189. Calcium-Activated Potassium (KCa) Channels 1 item
  190. Insulin Receptors 1 item
  191. IRG-1R 1 item
  192. cAMP 1 item
  193. Sulfonylurea receptors 1 item
  194. eEF-2 1 item
  195. Cdc7 1 item
  196. CMV 1 item
  197. ZAP-70 1 item
  198. Catechol O-Methyltransferase (COMT) 1 item
  199. fibrinolysis 1 item
  200. D4 Receptors 1 item
  201. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  202. Flk-1 1 item
  203. Papains 1 item
  204. Protein Arginine Methyltransferases 1 item
  205. NAE 2item
  206. Ubiquitin-activating Enzyme E1 1 item
  207. SUMOylation 1 item
  208. Cytidine deaminases 1 item
  209. angiogenesis 1 item
  210. DPP-4 1 item
  211. PP4 1 item
  212. c-RET 2item
  213. p70 rsk 2item
  214. VEGFR3/FLT4 1 item
  215. NTRK1/TRKA 1 item
  216. CSF-1R/c-Fms 1 item
  217. NMPRTase 1 item
  218. Bfl-1 1 item
  219. TAM kinase 1 item
  220. p53-MDM2 interaction 1 item
  221. nuclear export 1 item
  222. CRM1 1 item
  223. KDR 2item
  224. AXL 1 item
  225. Glyoxalase I 1 item
  226. ERAD 1 item
  227. p53 2item
  228. HDAC 1 item
  229. human lyase 1 item
  230. insulin 1 item
  231. Ub-conjugating enzyme (E2) complex 1 item
  232. Smoothened receptor 1 item
  233. Hec1 1 item
  234. GLI 1 item
  235. ErbB-2 1 item
  236. PDK-1 1 item
  237. Prk 1 item
  238. Ribonucleotide Reductases 1 item
  239. Trx 1 item
  240. HSP70 1 item
  241. TYK2 1 item
  242. MUSK 1 item
  243. MAP3K 1 item
  244. Adenosine Deaminases 1 item
  245. Flk1 2item
  246. DHFR 1 item
  247. GARFT 1 item
  248. RHA 1 item
  249. MCL1 1 item
  250. Bcl-w 1 item
  251. tropomyosin receptor kinase 1 item
  252. LSD 1 item
  253. DDX3 1 item
  254. SK 1 item
  255. PPK 1 item
  256. c-Syk 1 item
  257. CDK1/CyclinB 1 item
  258. IDO 1 item
  259. PIM1 kinase 1 item
  260. phospholipase A2 1 item
  261. Substance P/NK1 Receptor 1 item
  262. Bax 1 item
Reported Experiments
  1. Animal Experiments 537item
  2. Cell Experiments 365item