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Search results for: 'gsk 3 inhibitor 1'

Items 251-260 of 903

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  1. EC 144
    B4920 EC 144
    Target: HSP90
    Summary: High affinity, potent and selective Hsp90 inhibitor
      <41.39 mg/mL
  2. SC-514
    B1585 SC-514
    Summary: ATP-competitive IKK-2 inhibitor, orally active
      insoluble in EtOH; insoluble in H2O; ≥50.4 mg/mL
  3. BS-181
    A3266 BS-181
    Target: Cyclin-Dependent Kinases
    Summary: CDK7 inhibitor,highly selective
      Soluble in DMSO
  4. L189
    B7426 L189
    Target: DNA Ligases
    Summary: inhibitor of human DNA ligases I, III and IV
      ≥62.5 mg/mL
  5. Lamotrigine
    B2249 Lamotrigine
     1 Citation
    Target: 5-HT receptors|sodium channel
    Summary: 5-HT inhibitor， sodium channel blocker
      insoluble in H2O; ≥12.3 mg/mL
  6. Thalidomide
    A4216 Thalidomide
    Target: Ubiquitin E3 Ligases
    Summary: Immunomodulatory agent,sedative drug,angiogenesis inhibitor
      insoluble in H2O; insoluble in EtOH; ≥11.8 mg/mL
  7. Diphenyleneiodonium chloride
    B6326 Diphenyleneiodonium chloride
    Target: NADPH Oxidases|NOS|GPR3
    Summary: iNOS and eNOS inhibitor,GPR3 Activator
      insoluble in H2O; insoluble in EtOH; ≥6.99 mg/mL
  8. FK 866 hydrochloride
    A8631 FK 866 hydrochloride
    Target: NMPRTase
    Summary: NMPRTase inhibitor
      ≥18.95 mg/mL
  9. LP533401 hcl
    B5823 LP533401 hcl
    Target: Tph
    Summary: Tph-1 inhibitor
      ≥56.3 mg/mL
  10. Ketoconazole
    A4316 Ketoconazole
    Target: Cytochrome P450 (CYP450)
    Summary: Inhibitor of cyclosporine oxidase and testosterone 6 beta-hydroxylase
      ≥23.4 mg/mL

Items 251-260 of 903

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  1. Signaling Pathways 851item
  2. Natural Products 16item
  3. Protein 2item
  4. Peptides 1 item
  5. Probes & Dyes 1 item
  6. Peptides & Proteins 4item
  7. Lab Reagents 13item
Specificity
  1. Selective 532item
  2. Non-Selective 4item
Reversibility
  1. Reversible 34item
  2. Irreversible 27item
Target
  1. Caspases 7item
  2. Cyclin-Dependent Kinases 21item
  3. Proteasome 11item
  4. Cathepsins 5item
  5. Histone Deacetylases (HDACs) 27item
  6. Inhibitor of apoptosis proteins (IAP) 1 item
  7. Akt 11item
  8. Bcl-2 8item
  9. PI3K 28item
  10. CXCR 3item
  11. Raf 10item
  12. Aurora Kinases 18item
  13. Bcl-xl 3item
  14. CSF-1R 4item
  15. Glycoproteins 1 item
  16. p97 1 item
  17. Gap Junctions 1 item
  18. MDM2 2item
  19. EZH2 3item
  20. mTOR 16item
  21. Bromodomains 5item
  22. AP-1 3item
  23. MMP 7item
  24. Thymidine Phosphorylases 1 item
  25. Androgen Receptors 3item
  26. Peptidylprolyl isomerases 1 item
  27. Acyl coenzyme A: cholesterol acyltransferases 1 item
  28. Myosin II ATPases 1 item
  29. DT-diaphorases 1 item
  30. Voltage-gated Potassium (KV) Channels 1 item
  31. MER 1 item
  32. FLT3 16item
  33. GSK-3 6item
  34. Factor Xa 4item
  35. LPA Receptors 2item
  36. P-glycoprotein (P-gp) 3item
  37. PLK 9item
  38. Chk 4item
  39. Eph Receptors 2item
  40. VEGFR 28item
  41. PDGFR 19item
  42. c-Kit 9item
  43. RET 2item
  44. IRAK 2item
  45. Bromodomain-containing proteins(BRDs) 1 item
  46. Phosphodiesterases (PDEs) 12item
  47. Mcl-1 5item
  48. Hydrolase 1 item
  49. Thymidylate Synthase 3item
  50. p38 7item
  51. PKB 1 item
  52. JNK 2item
  53. Bcr-Abl 10item
  54. MEK 8item
  55. PORCN 1 item
  56. DOT1L 1 item
  57. FGFR 10item
  58. Nrf2 1 item
  59. Pim 4item
  60. Liver X receptors (LXRs) 2item
  61. Sir2-like Family Deacetylases (Sirtuins) 1 item
  62. Voltage-gated Sodium (NaV) Channels 2item
  63. Deubiquitinating enzymes (DUBs) 2item
  64. PP1 1 item
  65. PP2A 1 item
  66. Smoothened 1 item
  67. Neuraminidases (NA) 1 item
  68. MET 5item
  69. Src 15item
  70. Trk Receptors 5item
  71. Aminopeptidases 2item
  72. NMDA Receptors 2item
  73. STAT 8item
  74. Microtubules/Tubulins 1 item
  75. Estrogen and Related Receptors 2item
  76. EGFR 19item
  77. Reverse Transcriptases 6item
  78. ROCK 7item
  79. Hypoxia Inducible Factors (HIFs) 1 item
  80. FAK 4item
  81. JAK 17item
  82. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  83. Syk 4item
  84. Progesterone Receptors 2item
  85. EZH1 1 item
  86. DNA-PK 6item
  87. HSP90 8item
  88. AMPK 1 item
  89. CCR 1 item
  90. Angiotensin AT2 Receptors 1 item
  91. CFTR 2item
  92. Topoisomerases 15item
  93. Cytochrome P450 (CYP450) 8item
  94. Ksp 1 item
  95. Renin 1 item
  96. ErbB 4item
  97. Toll-like receptors (TLRs) 3item
  98. Actin 2item
  99. Serine Proteases 1 item
  100. DNA Methyltransferases 3item
  101. ERK 7item
  102. HMG-CoA Reductases 4item
  103. c-MET 6item
  104. PKC 11item
  105. Calpains 3item
  106. Ca2 /calmodulin-dependent protein kinases (CaMKs) 5item
  107. Protease-Activated Receptors 1 item
  108. Lyn 1 item
  109. RAD51 1 item
  110. HER2 1 item
  111. Pyk2 2item
  112. USP 1 item
  113. 5-HT2 Receptors 4item
  114. LRRK2 5item
  115. Voltage-gated Calcium Channels (CaV) 2item
  116. DGAT 1 item
  117. Insulin and Insulin-like Receptors 4item
  118. PARP 7item
  119. CB1 Receptors 2item
  120. Pyruvate dehydrogenases (PDH) 1 item
  121. ALK 7item
  122. Sphingosine kinases (SphKs) 2item
  123. Monocarboxylate transporters (MCTs) 1 item
  124. CETP 1 item
  125. PKG 2item
  126. PKA 5item
  127. Myosin light chain kinases (MLCKs) 2item
  128. GPR30 1 item
  129. D1 and D5 Receptors 1 item
  130. D2 Receptors 3item
  131. D3 Receptors 2item
  132. 5-HT1 Receptors 2item
  133. 5-HT7 Receptors 1 item
  134. Lactate Dehydrogenases (LDH) 2item
  135. MK2 2item
  136. 5-HT3 Receptors 1 item
  137. Angiotensin-Converting Enzymes (ACEs) 5item
  138. Tie-2 3item
  139. RSK 2item
  140. Free Fatty Acid Receptors 1 item
  141. phosphatases 2item
  142. Autophagy 3item
  143. ATM/ATR 5item
  144. COX 11item
  145. YAP 1 item
  146. CK1 1 item
  147. Histamine H4 Receptors 2item
  148. CK2 4item
  149. HIPK2 1 item
  150. HIPK3 1 item
  151. HIV Integrases 2item
  152. Pregnane X Receptors 1 item
  153. Squalene epoxidases 1 item
  154. PRAK 1 item
  155. MAPKAP-K2 1 item
  156. GpIIb/IIIa receptor 1 item
  157. Guanine nucleotide exchange factors (GEFs) 1 item
  158. 20S proteasomal chymotrypsin 1 item
  159. Geranylgeranyltransferase I 1 item
  160. Farnesyltransferase 1 item
  161. Nampt 3item
  162. eIF4F 1 item
  163. Cdc42 1 item
  164. SRPK1 1 item
  165. P2X Receptors 2item
  166. Glutaminases 2item
  167. Carbonic Anhydrases 7item
  168. Ron 1 item
  169. G9a 1 item
  170. BLM 1 item
  171. HSV 2item
  172. NADPH Oxidases 3item
  173. Calcium-activated chloride channels (CaCC) 1 item
  174. GPR35 1 item
  175. Aldehyde Dehydrogenases 2item
  176. Synthases/Synthetases 2item
  177. MAGL 2item
  178. NPY Receptors 1 item
  179. Leukotriene and Related Receptors 1 item
  180. Histamine H1 Receptors 6item
  181. RAR/RXR 1 item
  182. Na /K ATPases 3item
  183. P110 1 item
  184. Hck 2item
  185. Inositol-requiring enzyme 1 (IRE1) 3item
  186. Na /K /Cl- Symporters (NKCCs) 2item
  187. GABAA Receptors 1 item
  188. Histamine H2 Receptors 1 item
  189. Phospholipases 1 item
  190. Monoamine oxidases (MAOs) 2item
  191. Organic anion transporters (OATs) 1 item
  192. TRP Channel 3item
  193. RNA Polymerases 3item
  194. DYRK 1 item
  195. Norepinephrine transporter 1 item
  196. 5-HT Transporters 3item
  197. Xanthine oxidoreductases 1 item
  198. Dihydroorotate dehydrogenase 1 item
  199. Guanylyl Cyclases 1 item
  200. Histone Demethylases 2item
  201. MNK 2item
  202. 5-Lipoxygenases 1 item
  203. NO Donors / Precursors 2item
  204. CB2 Receptors 2item
  205. Glucocorticoid Receptors 3item
  206. HIV-1 reverse transcriptase 1 item
  207. IL Receptors 2item
  208. CCL2 1 item
  209. Noradrenaline reuptake 1 item
  210. Norepinephrine transporters 1 item
  211. 15-lipoxygenases 1 item
  212. Calcium-Activated Potassium (KCa) Channels 2item
  213. AChE 3item
  214. Insulin Receptors 1 item
  215. IRG-1R 1 item
  216. cAMP 1 item
  217. Sulfonylurea receptors 1 item
  218. Cdc2-like kinase (Clk) 1 item
  219. eEF-2 1 item
  220. Inward Rectifier Potassium (Kir) Channels 3item
  221. CRTH2 1 item
  222. Cdc7 1 item
  223. Nuclear Receptors 1 item
  224. CMV 1 item
  225. ZAP-70 1 item
  226. Catechol O-Methyltransferase (COMT) 2item
  227. fibrinolysis 1 item
  228. Angiotensin AT1 Receptors 3item
  229. D4 Receptors 1 item
  230. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  231. NMDA receptor 1 item
  232. HBV Proteases 1 item
  233. Hydroxylases 2item
  234. Flk-1 1 item
  235. Adenine receptors 1 item
  236. Antioxidants 1 item
  237. Papains 1 item
  238. Protein Arginine Methyltransferases 1 item
  239. IMPDH 1 item
  240. Na /Ca2 Exchangers (NCXs) 1 item
  241. NAE 2item
  242. Ubiquitin-activating Enzyme E1 2item
  243. SUMOylation 1 item
  244. ATGL 1 item
  245. BACE 2item
  246. Cytidine deaminases 1 item
  247. angiogenesis 1 item
  248. Glucagon Receptors 1 item
  249. 15-PGDH 1 item
  250. DPP-4 5item
  251. PP4 1 item
  252. c-RET 3item
  253. Nonstructural protein 5B (NS5B) 1 item
  254. guanylyl cyclase 1 item
  255. ETA Receptors 2item
  256. ETB Receptors 1 item
  257. p70 rsk 3item
  258. voltage-gated chloride channels 1 item
  259. FPTase 1 item
  260. 5-HT1 Receptor 1 item
  261. Microtubule/Tubulin 1 item
  262. Myosin 1 item
  263. VEGFR3/FLT4 1 item
  264. NTRK1/TRKA 1 item
  265. CSF-1R/c-Fms 1 item
  266. interleukin receptor 1 item
  267. Menin-MLL 2item
  268. Tryptophan hydroxylases (TPH) 2item
  269. ADAMs 1 item
  270. NMPRTase 1 item
  271. Bfl-1 1 item
  272. TAM kinase 1 item
  273. p53-MDM2 interaction 2item
  274. nuclear export 1 item
  275. CRM1 1 item
  276. PTP 1 item
  277. KDR 2item
  278. Fyn kinase 1 item
  279. Abl kinases 1 item
  280. Trypsin-like protease 1 item
  281. AXL 1 item
  282. Glyoxalase I 1 item
  283. dCTP Pyrophosphatases 1 item
  284. Protein polybromo-1 1 item
  285. SMARCA4 1 item
  286. SMARCA2 1 item
  287. ERAD 1 item
  288. Dipeptidyl-peptidase II 1 item
  289. p53 5item
  290. metalloprotease 1 item
  291. HDAC 2item
  292. Antifungal 1 item
  293. KDM 2item
  294. 5-HT receptors 1 item
  295. sodium channel 3item
  296. c-Fms tyrosine kinase 1 item
  297. PAR 1 item
  298. human lyase 1 item
  299. insulin 1 item
  300. Ub-conjugating enzyme (E2) complex 1 item
  301. Smoothened receptor 1 item
  302. quinone oxidoreductase 1 item
  303. lipase 1 item
  304. cysteine protease 2item
  305. PPAR 1 item
  306. STK 1 item
  307. USP1/USF1 complex 1 item
  308. IKK 1 item
  309. MSK 1 item
  310. gp120-CD4 interaction 1 item
  311. TRPV 1 item
  312. HCV polymerase 3item
  313. Ftase 1 item
  314. Subtilisin/Kex2p-like proprotein convertase 1 item
  315. PC-PLC 2item
  316. Elastases 1 item
  317. P97 ATPase 1 item
  318. ATP synthase 1 item
  319. Glucosidases 1 item
  320. NTPDases 1 item
  321. Vitamin D receptors (VDRs) 2item
  322. Antibiotic 5item
  323. Mer tyrosine kinase 1 item
  324. Hec1 1 item
  325. EAA receptor 1 item
  326. neprilysin 1 item
  327. GLI 1 item
  328. decarboxylase 1 item
  329. Stem Cell Differentiation 1 item
  330. PP2A/Nkd interaction 1 item
  331. Rev-Erb Receptors 1 item
  332. HMGCR 1 item
  333. AAT 1 item
  334. ErbB-2 1 item
  335. adrenergic receptor 3item
  336. HIV 1 item
  337. 5-HT4 Receptor 1 item
  338. PAR receptor 1 item
  339. TRPA 1 item
  340. sterol demethylase 1 item
  341. PDK-1 1 item
  342. GAPDH 1 item
  343. telomerase 1 item
  344. Histone Acetyltransferases (HATs) 3item
  345. complex I of the mitochondrial electron transport chain 1 item
  346. F1 Fo-ATPase 1 item
  347. Prk 1 item
  348. potassium channel 1 item
  349. calcium channel 1 item
  350. Ribonucleotide Reductases 1 item
  351. Trx 1 item
  352. Tyrosinases 1 item
  353. Neurokinin receptor 1 item
  354. HSP70 1 item
  355. ICAM 1 item
  356. ITK 1 item
  357. HIF-PH 1 item
  358. NOD1 1 item
  359. troponin 1 item
  360. NUAK 1 item
  361. Rho 1 item
  362. Aryl hydrocarbon receptors (AHRs) 1 item
  363. Ubiquitin E3 Ligases 1 item
  364. DCLK2 1 item
  365. FAAH 1 item
  366. PTK 1 item
  367. integrase 1 item
  368. L3MBTL 1 item
  369. phosphatidylinositol kinase 1 item
  370. NOS 2item
  371. MDMX 1 item
  372. TYK2 2item
  373. MUSK 1 item
  374. MAP3K 1 item
  375. GPR3 1 item
  376. AMPA Receptors 1 item
  377. Lck 1 item
  378. Adenosine Deaminases 2item
  379. mitochondrial pyruvate carrier (MPC) 1 item
  380. DNA gyrase 1 item
  381. prolactin secretion 1 item
  382. gonadotropin release 1 item
  383. DprE 1 item
  384. Vitamin D 1 item
  385. carnitine reabsorption 1 item
  386. Histamine receptors 1 item
  387. GluR 1 item
  388. 5-HT receptor 1 item
  389. dopamine receptors 1 item
  390. AMPA receptor 1 item
  391. 5-alpha Reductases 1 item
  392. Flk1 2item
  393. SAPK 1 item
  394. p21 1 item
  395. DNA Ligases 1 item
  396. NOP Receptors 1 item
  397. Prostaglandin synthesis 1 item
  398. Protein Tyrosine Phosphatases 1 item
  399. alkaline phosphatases 1 item
  400. ATPases 1 item
  401. glutamate release 1 item
  402. PAFR 1 item
  403. Aromatases 2item
  404. DHFR 1 item
  405. GARFT 1 item
  406. 5-HT 1 item
  407. PHF 1 item
  408. FGR 1 item
  409. YES 2item
  410. Fyn 2item
  411. ARG 1 item
  412. Autotaxin 1 item
  413. UCH 1 item
  414. RHA 1 item
  415. HCV NS3-4A protease 1 item
  416. PKD 1 item
  417. Octamer-binding transcription factor 4 (Oct4) 1 item
  418. Pyruvate kinases 1 item
  419. Thioredoxin Reductases 1 item
  420. enoyl-acyl-carrier protein reductase 1 item
  421. SHIP 1 item
  422. HMG 1 item
  423. HSD 1 item
  424. MCL1 1 item
  425. Bcl-w 1 item
  426. glutathione peroxidase 4 1 item
  427. NADH oxidase 1 item
  428. S-adenosylhomocysteine hydrolase 1 item
  429. Rho-kinase 1 item
  430. tropomyosin receptor kinase 1 item
  431. LSD 1 item
  432. DDX3 1 item
  433. PRMT 1 item
  434. ACE 1 item
  435. GLP 1 item
  436. SK 1 item
  437. MST 1 item
  438. PPK 1 item
  439. c-Syk 1 item
  440. CDK1/CyclinB 1 item
  441. NHE 1 item
  442. IDO 2item
  443. Tph 1 item
  444. PIM1 kinase 1 item
  445. phospholipase A2 1 item
  446. reverse transcriptase 1 item
  447. epoxide hydrolase 1 item
  448. ghrelin receptor 1 item
  449. Serotonin (5-HT) reuptake 1 item
  450. Cholesterol absorption 1 item
  451. Vascular Disrupting Agents (VDA) 1 item
  452. Androgen Receptor 1 item
  453. Substance P/NK1 Receptor 1 item
  454. gp120/CD4 1 item
  455. ATM 1 item
  456. Sirtuin 1 item
  457. NE 1 item
  458. CRF1 Receptors 1 item
  459. PIKfyve 1 item
  460. Bax 1 item
  461. Glycogen Phosphorylases 1 item
  462. MTH1 1 item
  463. PTEN 1 item
  464. Insulin Receptor 1 item
  465. NS3/4a Proteases 1 item
  466. p90 S6K 1 item
Related Disease
  1. Acne 2item
  2. Acute Kidney Injury 3item
  3. Acute Lung Injury 1 item
  4. Acute Myelogenous Leukemia 4item
  5. Acute Myeloid Leukemia 19item
  6. Acute Renal Failure 1 item
  7. Adrenocortical Carcinoma 3item
  8. Biliary Cancer 1 item
  9. Bladder Cancer 9item
  10. Bladder Carcinoma 3item
  11. Bladder Diseases 2item
  12. B-lymphoid Malignancies 1 item
  13. Brain Injuries Studies 3item
  14. Breast Cancer 77item
  15. Cancer 365item
  16. Castration-resistant Prostate Cancer 1 item
  17. Cervical Cancer 4item
  18. Cholangiocarcinoma 1 item
  19. Chronic Lymphocytic Leukemia 6item
  20. Chronic Myeloproliferative Disorders 1 item
  21. Clear Cell Renal Cell Carcinoma 1 item
  22. Cocaine-Related Disorders 2item
  23. Colon Cancer 23item
  24. Colon Carcinoma 3item
  25. Colorectal Cancer 28item
  26. Depression 2item
  27. Diabetes 7item
  28. Diffuse Large B-cell Lymphoma 1 item
  29. Dyskinesia 1 item
  30. Dyslipidemia 2item
  31. Epilepsy 3item
  32. Erectile Dysfunction 3item
  33. Friedreich's Ataxia 2item
  34. Fungi 1 item
  35. Glioblastoma 19item
  36. Glioma 11item
  37. HCV 3item
  38. Heart Failure 7item
  39. Hepatitis C 3item
  40. Hepatocellular Carcinoma 5item
  41. HIV 11item
  42. HIV Infections 12item
  43. Hypercholesterolemia 1 item
  44. Inflammation 1 item
  45. Inflammatory Diseases 8item
  46. Influenza 1 item
  47. Kidney Injury Studies 3item
  48. Leukemia 19item
  49. Liver Cancer 2item
  50. Lung Cancer 21item
  51. Lung Carcinoma 2item
  52. Lymphoma 26item
  53. Mantle Cell Lymphoma 2item
  54. Melanoma 20item
  55. Mixed Lineage Leukemia 1 item
  56. Multiple Myeloma 15item
  57. Myelofibrosis 2item
  58. Myeloma 3item
  59. Narcolepsy 1 item
  60. Neuroblastoma 7item
  61. Neurocognitive Disorders 1 item
  62. Neuronal Protection 1 item
  63. Non-small Cell Lung Cancer 15item
  64. Non-small Cell Lung Carcinoma 1 item
  65. Obsessive-Compulsive Disorder 1 item
  66. Osteoporosis 2item
  67. Ovarian Cancer 22item
  68. Pancreatic Cancer 31item
  69. Pancreatic Carcinoma 1 item
  70. Pentacyclic Triterpenoid 1 item
  71. Prostate Cancer 39item
  72. Psoriasis 3item
  73. Psoriasis Vulgaris 1 item
  74. Pulmonary Fibrosis 2item
  75. Renal Cancer 3item
  76. Renal Cell Carcinoma 5item
  77. Rheumatoid Arthritis 11item
  78. Sarcoma 1 item
  79. Schizophrenia 6item
  80. Sleep Disorders 2item
  81. Soft Tissue Sarcoma 1 item
  82. Squamous Cell Carcinoma 2item
  83. Thyroid Cancer 4item
  84. Tuberculosis 3item
  85. Type 2 Diabetes 11item