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  • Search results for: 'gsk 3 inhibitor 1'

Search results for: 'gsk 3 inhibitor 1'

Items 381-390 of 915

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  1. Dovitinib (TKI-258, CHIR-258)
    A2168 Dovitinib (TKI-258, CHIR-258)
     2 Citation
    Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Multitargeted RTK inhibitor
      insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
  2. CRT0044876
    B3061 CRT0044876
    Target: AP endonucleases
    Summary: APE1 inhibitor, potent and selective
      ≥55.56 mg/mL
  3. Cediranib (AZD217)
    A1882 Cediranib (AZD217)
    Target: VEGFR
    Summary: VEGFR inhibitor receptor,highly potent
      ≥22.52 mg/mL
  4. Remodelin
    B4887 Remodelin
    Target: NAT10
    Summary: NAT10 inhibitor
      ≥36.3 mg/mL
  5. DBeQ
    A8629 DBeQ
    Target: P97 ATPase
    Summary: P97 ATPase inhibitor
      ≥16 mg/mL
  6. SU5416
    A3847 SU5416
    Target: VEGFR
    Summary: VEGF receptor inhibitor and AHR agonist
      insoluble in EtOH; insoluble in H2O; ≥11.9 mg/mL
  7. AG-1478
    A8357 AG-1478
    Target: EGFR
    Summary: EGFR inhibitor,potent and selective
      insoluble in H2O; ≥15.8 mg/mL
  8. SP2509
    B4894 SP2509
    Target: Histone Demethylases
    Summary: Demethylase 1 (LSD1) antagonist, novel Lysine-specific
      insoluble in H2O; insoluble in EtOH; ≥19.45 mg/mL
  9. GDC-0449 (Vismodegib)
    A3021 GDC-0449 (Vismodegib)
     1 Citation
    Target: P-glycoprotein (P-gp)|Hedgehog
    Summary: Hedgehog antagonist,potent and selective
      ≥21.08 mg/mL
  10. LY 294002
    A8250 LY 294002
     16 Citation
    Target: PI3K
    Summary: Potent PI3K inhibitor

Items 381-390 of 915

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  1. Signaling Pathways 877item
  2. Natural Products 5item
  3. Other Products 1 item
  4. Kits 1 item
  5. Probes & Dyes 1 item
  6. Cell Biology 2item
  7. Peptides & Proteins 1 item
  8. Lab Reagents 7item
Reversibility
  1. Reversible 54item
  2. Irreversible 29item
Target
  1. Caspases 12item
  2. Cyclin-Dependent Kinases 26item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 11item
  5. Cathepsins 11item
  6. Histone Deacetylases (HDACs) 28item
  7. Inhibitor of apoptosis proteins (IAP) 3item
  8. Akt 6item
  9. Bcl-2 6item
  10. PI3K 27item
  11. CXCR 5item
  12. Raf 10item
  13. Aurora Kinases 14item
  14. Bcl-xl 3item
  15. CSF-1R 2item
  16. Glycoproteins 1 item
  17. p97 1 item
  18. Gap Junctions 1 item
  19. MDM2 2item
  20. EZH2 6item
  21. mTOR 15item
  22. Bromodomains 5item
  23. AP-1 3item
  24. MMP 10item
  25. Thymidine Phosphorylases 1 item
  26. Androgen Receptors 4item
  27. Peptidylprolyl isomerases 1 item
  28. Acyl coenzyme A: cholesterol acyltransferases 1 item
  29. Myosin II ATPases 1 item
  30. DT-diaphorases 1 item
  31. Voltage-gated Potassium (KV) Channels 1 item
  32. MER 1 item
  33. FLT3 12item
  34. GSK-3 9item
  35. Factor Xa 3item
  36. LPA Receptors 1 item
  37. P-glycoprotein (P-gp) 5item
  38. PLK 7item
  39. Chk 8item
  40. ULK1 1 item
  41. Eph Receptors 3item
  42. VEGFR 25item
  43. PDGFR 19item
  44. c-Kit 7item
  45. RET 3item
  46. IRAK 3item
  47. Bromodomain-containing proteins(BRDs) 1 item
  48. Phosphodiesterases (PDEs) 10item
  49. Mcl-1 5item
  50. Hydrolase 1 item
  51. Thymidylate Synthase 2item
  52. p38 9item
  53. PKB 1 item
  54. 3-phosphoglycerate dehydrogenase 1 item
  55. JNK 6item
  56. SGK 2item
  57. Bcr-Abl 10item
  58. Kynurenine-3-monooxygenase 1 item
  59. MEK 15item
  60. PORCN 1 item
  61. DOT1L 3item
  62. FGFR 9item
  63. Nrf2 2item
  64. Insulin-like growth factor receptors(IGFRs) 1 item
  65. CGRP receptors 1 item
  66. Pim 5item
  67. Liver X receptors (LXRs) 1 item
  68. Glucagon-like peptide 1 (GLP-1) receptors 2item
  69. Sir2-like Family Deacetylases (Sirtuins) 2item
  70. Voltage-gated Sodium (NaV) Channels 1 item
  71. Deubiquitinating enzymes (DUBs) 4item
  72. PP1 1 item
  73. PP2A 1 item
  74. Smoothened 4item
  75. Eukaryotic elongation factors 1 item
  76. Ribosomal s6 kinases (RSK) 1 item
  77. Neuraminidases (NA) 1 item
  78. MET 7item
  79. Src 9item
  80. Trk Receptors 7item
  81. Integrins 1 item
  82. Aminopeptidases 2item
  83. STAT 7item
  84. ATP Citrate Lyases 1 item
  85. Microtubules/Tubulins 6item
  86. Estrogen and Related Receptors 1 item
  87. EGFR 15item
  88. Hedgehog 1 item
  89. Reverse Transcriptases 1 item
  90. ROCK 7item
  91. BTK 2item
  92. RIP kinases 1 item
  93. Monocyte chemotactic proteins 1 item
  94. PAK 3item
  95. Hypoxia Inducible Factors (HIFs) 2item
  96. Tankyrases 1 item
  97. Inositol Phosphatases 1 item
  98. FAK 5item
  99. BMP and Other Activin Receptors 4item
  100. JAK 13item
  101. p300 1 item
  102. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  103. Syk 7item
  104. Progesterone Receptors 2item
  105. EZH1 2item
  106. DNA-PK 6item
  107. HSP90 10item
  108. AMPK 3item
  109. Gutathione S-transferase 1 item
  110. CCR 2item
  111. PDHK 1 item
  112. Angiotensin AT2 Receptors 2item
  113. eIF4E/eIF3G interaction 1 item
  114. Notch 1 item
  115. S-nitrosoglutathione reductase 1 item
  116. CFTR 3item
  117. TNKS 1 item
  118. Topoisomerases 9item
  119. Cytochrome P450 (CYP450) 6item
  120. thrombin 1 item
  121. Ksp 1 item
  122. Ribosomes 1 item
  123. Renin 2item
  124. HIV proteases 1 item
  125. Pepsins 1 item
  126. Influenza viruses 1 item
  127. ErbB 2item
  128. Ferroptosis 1 item
  129. S6 kinases 1 item
  130. Toll-like receptors (TLRs) 3item
  131. Adenosine Kinases 2item
  132. Actin 2item
  133. DNA Methyltransferases 4item
  134. Survivin 1 item
  135. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  136. ERK 5item
  137. HMG-CoA Reductases 5item
  138. Vacuolar-type ATPase 1 item
  139. c-MET 8item
  140. BMI-1 1 item
  141. PKC 8item
  142. Calpains 6item
  143. Ubiquitin-specific proteases 1 item
  144. HCV Proteases 3item
  145. Ca2 /calmodulin-dependent protein kinases (CaMKs) 8item
  146. MLK3 1 item
  147. SMYD2 1 item
  148. O-GlcNAcase 1 item
  149. CREBBP 2item
  150. EP300 2item
  151. Protease-Activated Receptors 1 item
  152. Lyn 1 item
  153. SGLT 1 item
  154. RAD51 1 item
  155. Trypsins 1 item
  156. HER2 2item
  157. Pyk2 3item
  158. USP 3item
  159. 5-HT2 Receptors 6item
  160. LRRK2 4item
  161. Voltage-gated Calcium Channels (CaV) 1 item
  162. Calcium chelator 1 item
  163. DGAT 2item
  164. Insulin and Insulin-like Receptors 3item
  165. PARP 5item
  166. CB1 Receptors 2item
  167. Pyruvate dehydrogenases (PDH) 1 item
  168. ALK 5item
  169. ROS1 2item
  170. Sphingosine kinases (SphKs) 2item
  171. Trypsin 1 item
  172. Chymotrypsin 1 item
  173. Kallikrein 1 item
  174. Trypsinogen 1 item
  175. KRAS G12C 1 item
  176. GTPases 1 item
  177. Monocarboxylate transporters (MCTs) 1 item
  178. CETP 2item
  179. Dehydrogenase 1 item
  180. PKG 1 item
  181. PKA 1 item
  182. Myosin light chain kinases (MLCKs) 2item
  183. GPR30 1 item
  184. BCPCF efflux 1 item
  185. HIV-1 gp120 1 item
  186. D1 and D5 Receptors 1 item
  187. D2 Receptors 4item
  188. D3 Receptors 2item
  189. 5-HT1 Receptors 2item
  190. 5-HT7 Receptors 1 item
  191. CaM-KK 1 item
  192. Valosin-containing protein (VCP) 1 item
  193. AdipoR1 1 item
  194. AdipoR2 1 item
  195. MELK 1 item
  196. Serotonin reuptake 1 item
  197. Insulin-like growth factors (IGFs) 1 item
  198. Clk 1 item
  199. TBK1 1 item
  200. MARK1 1 item
  201. NUAK1 2item
  202. Integrin-ligand interactions 1 item
  203. CSF1R 1 item
  204. Bromodomain and Extra-Terminal motif (BET) 1 item
  205. NUAK2 1 item
  206. Na /H Exchangers (NHEs) 1 item
  207. Lactate Dehydrogenases (LDH) 2item
  208. MK2 3item
  209. Fatty-acid-binding proteins (FABPs) 1 item
  210. 5-HT3 Receptors 1 item
  211. Angiotensin-Converting Enzymes (ACEs) 4item
  212. Tie-2 4item
  213. RSK 2item
  214. p70 S6K 1 item
  215. Granzyme B 1 item
  216. Free Fatty Acid Receptors 3item
  217. phosphatases 1 item
  218. Autophagy 2item
  219. ATM/ATR 7item
  220. Mixed lineage kinase domain-like protein (MLKL) 1 item
  221. COX 7item
  222. Heparanases 1 item
  223. YAP 1 item
  224. CK1 1 item
  225. IDH2 1 item
  226. Histamine H4 Receptors 2item
  227. CK2 3item
  228. HIPK2 1 item
  229. HIPK3 1 item
  230. HIV Integrases 2item
  231. Pregnane X Receptors 1 item
  232. Cryptochromes 1 item
  233. G-quadruplexes 1 item
  234. Squalene epoxidases 2item
  235. PRAK 1 item
  236. MAPKAP-K2 1 item
  237. Delayed rectifier outward potassium current (IKr) 1 item
  238. GpIIb/IIIa receptor 1 item
  239. Melatonin Receptors 1 item
  240. Guanine nucleotide exchange factors (GEFs) 1 item
  241. 20S proteasomal chymotrypsin 1 item
  242. Geranylgeranyltransferase I 1 item
  243. Farnesyltransferase 1 item
  244. NAT10 1 item
  245. Nampt 2item
  246. eIF4F 1 item
  247. Cdc42 1 item
  248. SRPK1 1 item
  249. P2X Receptors 2item
  250. Glutaminases 1 item
  251. Carbonic Anhydrases 6item
  252. Ron 1 item
  253. AP endonucleases 1 item
  254. G9a 2item
  255. BLM 1 item
  256. HSV 2item
  257. NADPH Oxidases 2item
  258. Calcium-activated chloride channels (CaCC) 1 item
  259. GPR35 1 item
  260. Aldehyde Dehydrogenases 2item
  261. Synthases/Synthetases 3item
  262. MAGL 2item
  263. NPY Receptors 1 item
  264. c-Fyn 1 item
  265. Leukotriene and Related Receptors 1 item
  266. TAK1 1 item
  267. Histamine H1 Receptors 3item
  268. Na /K ATPases 2item
  269. P110 1 item
  270. Hck 1 item
  271. Inositol-requiring enzyme 1 (IRE1) 2item
  272. SETD7 1 item
  273. Na /K /Cl- Symporters (NKCCs) 1 item
  274. GABAA Receptors 1 item
  275. iNOS 1 item
  276. Histamine H2 Receptors 1 item
  277. Phospholipases 1 item
  278. Organic anion transporters (OATs) 1 item
  279. TRP Channel 3item
  280. RNA Polymerases 2item
  281. DYRK 1 item
  282. Norepinephrine transporter 1 item
  283. 5-HT Transporters 3item
  284. Xanthine oxidoreductases 1 item
  285. Dihydroorotate dehydrogenase 1 item
  286. Guanylyl Cyclases 1 item
  287. Histone Demethylases 2item
  288. Apoptosis Inducers 1 item
  289. MNK 1 item
  290. NO Donors / Precursors 2item
  291. CB2 Receptors 2item
  292. Glucocorticoid Receptors 2item
  293. HIV-1 reverse transcriptase 1 item
  294. IL Receptors 2item
  295. CCL2 1 item
  296. Para-aminobenzoic acid 1 item
  297. Noradrenaline reuptake 1 item
  298. Norepinephrine transporters 1 item
  299. 15-lipoxygenases 1 item
  300. Calcium-Activated Potassium (KCa) Channels 1 item
  301. AChE 2item
  302. Insulin Receptors 1 item
  303. IRG-1R 1 item
  304. Proton Pump 1 item
  305. cAMP 1 item
  306. Sulfonylurea receptors 1 item
  307. Cdc2-like kinase (Clk) 1 item
  308. eEF-2 1 item
  309. Inward Rectifier Potassium (Kir) Channels 3item
  310. Arp2/3 complex 1 item
  311. CRTH2 1 item
  312. Cdc7 1 item
  313. Nuclear Receptors 1 item
  314. CMV 1 item
  315. ZAP-70 1 item
  316. Catechol O-Methyltransferase (COMT) 2item
  317. fibrinolysis 1 item
  318. Angiotensin AT1 Receptors 2item
  319. D4 Receptors 1 item
  320. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  321. HBV Proteases 1 item
  322. Flk-1 1 item
  323. Adenine receptors 1 item
  324. Papains 1 item
  325. Protein Arginine Methyltransferases 1 item
  326. IMPDH 1 item
  327. Na /Ca2 Exchangers (NCXs) 1 item
  328. NAE 2item
  329. Ubiquitin-activating Enzyme E1 1 item
  330. SUMOylation 1 item
  331. ATGL 1 item
  332. BACE 1 item
  333. Cytidine deaminases 1 item
  334. angiogenesis 1 item
  335. Glucagon Receptors 1 item
  336. 15-PGDH 1 item
  337. DPP-4 4item
  338. PP4 1 item
  339. c-RET 1 item
  340. Nonstructural protein 5B (NS5B) 1 item
  341. ETA Receptors 2item
  342. ETB Receptors 1 item
  343. p70 rsk 1 item
  344. FPTase 1 item
  345. ADAMs 1 item
  346. TAM kinase 1 item
  347. p53-MDM2 interaction 1 item
  348. nuclear export 1 item
  349. CRM1 1 item
  350. AXL 1 item
  351. Protein polybromo-1 1 item
  352. SMARCA4 1 item
  353. SMARCA2 1 item
  354. Dipeptidyl-peptidase II 1 item
  355. HDAC 1 item
  356. c-Fms tyrosine kinase 1 item
  357. human lyase 1 item
  358. Ub-conjugating enzyme (E2) complex 1 item
  359. STK 1 item
  360. IKK 1 item
  361. MSK 1 item
  362. HCV polymerase 2item
  363. Ftase 1 item
  364. PC-PLC 1 item
  365. Elastases 1 item
  366. P97 ATPase 1 item
  367. NTPDases 1 item
  368. Rev-Erb Receptors 1 item
  369. telomerase 1 item
  370. Histone Acetyltransferases (HATs) 1 item
  371. F1 Fo-ATPase 1 item
  372. ITK 1 item
  373. NOD1 1 item
  374. NUAK 1 item
  375. DCLK2 1 item
  376. FAAH 1 item
  377. TYK2 1 item
  378. Lck 1 item
  379. NOP Receptors 1 item
  380. Aromatases 1 item
  381. PKD 1 item
  382. SHIP 1 item
  383. MCL1 1 item
  384. Bcl-w 1 item
  385. tropomyosin receptor kinase 1 item
  386. LSD 1 item
  387. PRMT 1 item
  388. GLP 1 item
  389. SK 1 item
  390. MST 1 item
  391. IDO 1 item
  392. Serotonin (5-HT) reuptake 1 item
  393. Androgen Receptor 1 item
  394. Substance P/NK1 Receptor 1 item
  395. gp120/CD4 1 item
  396. ATM 2item
  397. Sirtuin 1 item
  398. NE 1 item
  399. CRF1 Receptors 1 item
  400. PIKfyve 1 item
  401. Glycogen Phosphorylases 1 item
  402. RGS 1 item
  403. MTH1 1 item
  404. Insulin Receptor 1 item
Reported Experiments
  1. Animal Experiments 777item
  2. Cell Experiments 532item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acne 1 item
  3. Acute Disseminated Candidiasis 1 item
  4. Acute Kidney Injury 2item
  5. Acute Lung Injury 1 item
  6. Acute Myelogenous Leukemia 6item
  7. Acute Myeloid Leukemia 28item
  8. Acute Renal Failure 1 item
  9. Adrenocortical Carcinoma 4item
  10. Advanced Renal Cell Carcinoma 1 item
  11. Autoimmune Diseases 1 item
  12. Biliary Cancer 1 item
  13. Bladder Cancer 10item
  14. Bladder Carcinoma 4item
  15. Bladder Diseases 2item
  16. B-lymphoid Malignancies 1 item
  17. Brain Injuries Studies 3item
  18. Breast Cancer 126item
  19. Cancer 466item
  20. Candida Peritonitis 1 item
  21. Candidemia 1 item
  22. Castration-resistant Prostate Cancer 1 item
  23. Cervical Cancer 5item
  24. Cholangiocarcinoma 2item
  25. Chronic Lymphocytic Leukemia 8item
  26. Chronic Myeloproliferative Disorders 1 item
  27. Clear Cell Renal Cell Carcinoma 2item
  28. Cocaine-Related Disorders 2item
  29. Colon Cancer 48item
  30. Colon Carcinoma 7item
  31. Colorectal Cancer 42item
  32. Depression 2item
  33. Diabetes 9item
  34. Diffuse Large B-cell Lymphoma 1 item
  35. Dyskinesia 1 item
  36. Dyslipidemia 2item
  37. Epilepsy 2item
  38. Erectile Dysfunction 3item
  39. Friedreich's Ataxia 2item
  40. Fungal Infection 1 item
  41. Glioblastoma 35item
  42. Glioma 19item
  43. HCV 3item
  44. Heart Failure 1 item
  45. Hepatic Cancer 2item
  46. Hepatitis C 3item
  47. Hepatocellular Carcinoma 8item
  48. HIV 5item
  49. HIV Infections 12item
  50. Hypercholesterolemia 2item
  51. Immunological Diseases 1 item
  52. Inflammation 1 item
  53. Inflammatory Bowel Disease 1 item
  54. Inflammatory Diseases 19item
  55. Influenza 2item
  56. Kidney Injury Studies 2item
  57. Leukemia 25item
  58. Liver Cancer 3item
  59. Lung Cancer 47item
  60. Lung Carcinoma 4item
  61. Lymphoma 35item
  62. Mantle Cell Lymphoma 2item
  63. Medulloblastoma 1 item
  64. Melanoma 38item
  65. Mixed Lineage Leukemia 3item
  66. Multiple Myeloma 24item
  67. Myelofibrosis 2item
  68. Myeloma 8item
  69. Narcolepsy 1 item
  70. Neuroblastoma 14item
  71. Neurocognitive Disorders 1 item
  72. Neuronal Protection 1 item
  73. Non-small Cell Lung Cancer 27item
  74. Non-small Cell Lung Carcinoma 2item
  75. Obsessive-Compulsive Disorder 1 item
  76. Osteoporosis 2item
  77. Ovarian Cancer 36item
  78. Pancreatic Cancer 51item
  79. Pancreatic Carcinoma 3item
  80. Prostate Cancer 63item
  81. Psoriasis 4item
  82. Psoriasis Vulgaris 1 item
  83. Pulmonary Arterial Hypertension 2item
  84. Pulmonary Fibrosis 2item
  85. Renal Cancer 4item
  86. Renal Cell Carcinoma 10item
  87. Rheumatoid Arthritis 14item
  88. Sarcoma 1 item
  89. Schizophrenia 9item
  90. Sleep Disorders 2item
  91. Soft Tissue Sarcoma 1 item
  92. Squamous Cell Carcinoma 2item
  93. Testicular Cancer 2item
  94. Thyroid Cancer 6item
  95. Tuberculosis 1 item
  96. Type 2 Diabetes 18item