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Search results for: 'gsk 3 inhibitor 1'

Search results for: 'gsk 3 inhibitor 1'

A3347 Dabrafenib Mesylate (GSK-2118436)

Target: Raf

Summary: Inhibitor of BRAF(V600) mutants

≥30.75 mg/mL
A3570 LY2090314

Target: GSK-3

Summary: Potent GSK-3 inhibitor

insoluble in H2O; ≥91 mg/mL
A8177 PAC-1

1 Citation

Target: Caspases

Summary: Procaspase-3 activator

insoluble in H2O; ≥13.4 mg/mL
A3887 Trametinib DMSO solvate

1 Citation

Target: MEK

Summary: Allosteric MEK1/MEK2 kinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥11.2 mg/mL
A3018 Trametinib (GSK1120212)

7 Citation

Target: MEK

Summary: MEK1 and MEK2 inhibitor, potent and selective

insoluble in H2O; insoluble in EtOH; ≥15.38 mg/mL
A4094 MC1568

3 Citation

Target: Histone Deacetylases (HDACs)

Summary: Class II HDAC inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥15.7 mg/mL
B1288 Rigosertib

Target: PI3K|PLK

Summary: PI3K/PLK1 inhibitor

Soluble in DMSO
A8721 CBR-5884

1 Citation

Target: 3-phosphoglycerate dehydrogenase

Summary: selective inhibitor of PHGDH

insoluble in EtOH; insoluble in H2O; ≥16.8 mg/mL
B1036 MLN4924

5 Citation

Target: NAE|Ubiquitin-activating Enzyme E1|SUMOylation

Summary: NAE inhibitor

≥22.18 mg/mL
A4381 FK866 (APO866)

1 Citation

Target: Nampt

Summary: NAMPT inhibitor, non-competitive, highly specific

insoluble in H2O; ≥19.6 mg/mL