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  • Search results for: 'mcl1 in 1'

Search results for: 'mcl1 in 1'

Items 181-190 of 404

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  1. Marinopyrrole A
    B1080 Marinopyrrole A
    Target: Mcl-1
    Summary: Selective Mcl-1 inhibitor
      Soluble in DMSO
  2. AVE 0991
    B1007 AVE 0991
     1 Citation
    Target: Angiotensin AT1 Receptors
    Summary: Agonist of angiotensin-(1-7) receptor
      ≥29.04 mg/mL
  3. VX-765
    A8238 VX-765
     1 Citation
    Target: Caspases
    Summary: Caspase-1 inhibitor,potent and selective
      insoluble in H2O; ≥313 mg/mL
  4. A-966492
    A4160 A-966492
    Target: PARP
    Summary: PARP-1/-2 inhibitor, highly potent
      ≥32.4 mg/mL
  5. PTC-209
    B3179 PTC-209
    Target: BMI-1
    Summary: Bmi-1 inhibitor,cell-permeable and small-molecule
      ≥24.75 mg/mL
  6. FK 866 hydrochloride
    A8631 FK 866 hydrochloride
    Target: NMPRTase
    Summary: NMPRTase inhibitor
      ≥18.95 mg/mL
  7. Boc-D-FMK
    A1904 Boc-D-FMK
     1 Citation
    Target: Caspases
    Summary: Pan-caspase inhibitor
      insoluble in H2O; ≥11.65 mg/mL
  8. Vorapaxar
    A8809 Vorapaxar
    Target: Protease-Activated Receptors
    Summary: PAR-1 antagonist,potent and orally active
      ≥24.65 mg/mL
  9. LP533401 hcl
    B5823 LP533401 hcl
    Target: Tph
    Summary: Tph-1 inhibitor
      ≥56.3 mg/mL
  10. INK 128 (MLN0128)
    A8551 INK 128 (MLN0128)
     4 Citation
    Target: mTOR
    Summary: MTOR(TORC-1/-2) inhibitor,potent and selective
      insoluble in H2O; ≥15.45 mg/mL

Items 181-190 of 404

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Category
  1. Proteases 32item
  2. Apoptosis 32item
  3. Chromatin/Epigenetics 42item
  4. Metabolism 25item
  5. MAPK Signaling 21item
  6. Tyrosine Kinase 50item
  7. DNA Damage/DNA Repair 30item
  8. PI3K/Akt/mTOR Signaling 24item
  9. Microbiology & Virology 23item
  10. Cell Cycle/Checkpoint 32item
  11. Ubiquitination/ Proteasome 5item
  12. JAK/STAT Signaling 13item
  13. TGF-β / Smad Signaling 12item
  14. Angiogenesis 4item
  15. GPCR/G protein 26item
  16. Stem Cell 15item
  17. Membrane Transporter/Ion Channel 13item
  18. Endocrinology and Hormones 12item
  19. Neuroscience 23item
  20. Obesity, Appetite Control & Diabetes 1 item
  21. Other Signal Transduction 3item
  22. Others 28item
  23. Immunology/Inflammation 12item
  24. Cardiovascular 3item
  25. Vitamin D Related 2item
  26. NF-κB 1 item
Specificity
  1. Selective 275item
  2. Non-Selective 2item
Reversibility
  1. Reversible 13item
  2. Irreversible 8item
Target
  1. Caspases 5item
  2. Cyclin-Dependent Kinases 10item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 1 item
  5. Cathepsins 3item
  6. Histone Deacetylases (HDACs) 10item
  7. Inhibitor of apoptosis proteins (IAP) 1 item
  8. Akt 5item
  9. Bcl-2 8item
  10. PI3K 10item
  11. CXCR 1 item
  12. Raf 7item
  13. Aurora Kinases 4item
  14. Bcl-xl 2item
  15. CSF-1R 1 item
  16. Gap Junctions 1 item
  17. MDM2 2item
  18. EZH2 1 item
  19. mTOR 10item
  20. Bromodomains 2item
  21. AP-1 3item
  22. MMP 6item
  23. Androgen Receptors 4item
  24. Acyl coenzyme A: cholesterol acyltransferases 1 item
  25. FLT3 10item
  26. GSK-3 2item
  27. Factor Xa 1 item
  28. LPA Receptors 3item
  29. PLK 6item
  30. Chk 3item
  31. VEGFR 22item
  32. PDGFR 14item
  33. c-Kit 6item
  34. RET 3item
  35. IRAK 1 item
  36. Bromodomain-containing proteins(BRDs) 1 item
  37. Phosphodiesterases (PDEs) 1 item
  38. Mcl-1 6item
  39. p38 4item
  40. PKB 1 item
  41. JNK 1 item
  42. SGK 1 item
  43. Bcr-Abl 5item
  44. MEK 5item
  45. PORCN 1 item
  46. DOT1L 1 item
  47. FGFR 4item
  48. Insulin-like growth factor receptors(IGFRs) 1 item
  49. CGRP receptors 1 item
  50. Pim 1 item
  51. Liver X receptors (LXRs) 1 item
  52. Glucagon-like peptide 1 (GLP-1) receptors 2item
  53. Sir2-like Family Deacetylases (Sirtuins) 3item
  54. Voltage-gated Sodium (NaV) Channels 1 item
  55. Deubiquitinating enzymes (DUBs) 1 item
  56. PP1 1 item
  57. PP2A 1 item
  58. Smoothened 2item
  59. Eukaryotic elongation factors 1 item
  60. MET 1 item
  61. Src 6item
  62. Trk Receptors 3item
  63. Aminopeptidases 3item
  64. NMDA Receptors 1 item
  65. STAT 4item
  66. Microtubules/Tubulins 3item
  67. Estrogen and Related Receptors 2item
  68. EGFR 2item
  69. ROCK 2item
  70. BTK 1 item
  71. RIP kinases 1 item
  72. PAK 1 item
  73. Hypoxia Inducible Factors (HIFs) 1 item
  74. BMP and Other Activin Receptors 1 item
  75. JAK 8item
  76. p300 1 item
  77. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  78. Syk 3item
  79. Progesterone Receptors 1 item
  80. EZH1 1 item
  81. DNA-PK 3item
  82. HSP90 1 item
  83. AMPK 1 item
  84. Gutathione S-transferase 1 item
  85. CCR 2item
  86. TNKS 1 item
  87. Topoisomerases 5item
  88. Cytochrome P450 (CYP450) 4item
  89. Toll-like receptors (TLRs) 3item
  90. DNA Methyltransferases 2item
  91. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  92. ERK 3item
  93. HMG-CoA Reductases 1 item
  94. c-MET 3item
  95. BMI-1 1 item
  96. PKC 6item
  97. Calpains 2item
  98. M1 Receptors 1 item
  99. HCV Proteases 1 item
  100. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  101. Protease-Activated Receptors 1 item
  102. RAD51 1 item
  103. 5-HT2 Receptors 3item
  104. LRRK2 2item
  105. Calcium chelator 1 item
  106. DGAT 2item
  107. Insulin and Insulin-like Receptors 2item
  108. PARP 5item
  109. CB1 Receptors 2item
  110. ALK 1 item
  111. Sphingosine kinases (SphKs) 2item
  112. Trypsin 1 item
  113. Chymotrypsin 1 item
  114. Kallikrein 1 item
  115. Trypsinogen 1 item
  116. Monocarboxylate transporters (MCTs) 2item
  117. PKG 1 item
  118. PKA 4item
  119. GPR30 1 item
  120. HIV-1 gp120 1 item
  121. D2 Receptors 1 item
  122. Lactate Dehydrogenases (LDH) 1 item
  123. MK2 1 item
  124. Tie-2 2item
  125. Free Fatty Acid Receptors 1 item
  126. phosphatases 1 item
  127. Autophagy 3item
  128. ATM/ATR 2item
  129. COX 6item
  130. YAP 1 item
  131. CK1 1 item
  132. CK2 1 item
  133. HIV Integrases 1 item
  134. Nampt 1 item
  135. P2X Receptors 1 item
  136. Glutaminases 1 item
  137. Carbonic Anhydrases 2item
  138. Ron 1 item
  139. BLM 1 item
  140. HSV 1 item
  141. NADPH Oxidases 1 item
  142. Calcium-activated chloride channels (CaCC) 1 item
  143. GPR35 1 item
  144. Aldehyde Dehydrogenases 1 item
  145. MAGL 1 item
  146. Leukotriene and Related Receptors 1 item
  147. Histamine H1 Receptors 1 item
  148. Inositol-requiring enzyme 1 (IRE1) 1 item
  149. Na /K /Cl- Symporters (NKCCs) 1 item
  150. TRP Channel 2item
  151. RNA Polymerases 1 item
  152. Norepinephrine transporter 1 item
  153. 5-HT Transporters 1 item
  154. Guanylyl Cyclases 1 item
  155. Histone Demethylases 1 item
  156. MNK 2item
  157. NO Donors / Precursors 1 item
  158. CB2 Receptors 1 item
  159. HIV-1 reverse transcriptase 1 item
  160. IL Receptors 1 item
  161. 15-lipoxygenases 1 item
  162. Insulin Receptors 1 item
  163. IRG-1R 1 item
  164. eEF-2 1 item
  165. CRTH2 1 item
  166. Nuclear Receptors 1 item
  167. ZAP-70 1 item
  168. Angiotensin AT1 Receptors 2item
  169. Protein Arginine Methyltransferases 1 item
  170. Na /Ca2 Exchangers (NCXs) 1 item
  171. Ubiquitin-activating Enzyme E1 1 item
  172. Glucagon Receptors 1 item
  173. PP4 1 item
  174. c-RET 1 item
  175. Nonstructural protein 5B (NS5B) 1 item
  176. guanylyl cyclase 1 item
  177. ETA Receptors 2item
  178. ETB Receptors 1 item
  179. p70 rsk 3item
  180. voltage-gated chloride channels 1 item
  181. 5-HT1 Receptor 1 item
  182. VEGFR3/FLT4 1 item
  183. NTRK1/TRKA 1 item
  184. CSF-1R/c-Fms 1 item
  185. Tryptophan hydroxylases (TPH) 1 item
  186. NMPRTase 1 item
  187. Bfl-1 1 item
  188. KDR 1 item
  189. Fyn kinase 1 item
  190. p53 4item
  191. metalloprotease 1 item
  192. Antifungal 1 item
  193. 5-HT receptors 1 item
  194. sodium channel 1 item
  195. c-Fms tyrosine kinase 1 item
  196. Smoothened receptor 1 item
  197. PPAR 1 item
  198. IKK 1 item
  199. Ftase 1 item
  200. Elastases 1 item
  201. ATP synthase 1 item
  202. Vitamin D receptors (VDRs) 1 item
  203. Antibiotic 2item
  204. Mer tyrosine kinase 1 item
  205. Hec1 1 item
  206. Stem Cell Differentiation 1 item
  207. PP2A/Nkd interaction 1 item
  208. HMGCR 1 item
  209. HIV 1 item
  210. TRPA 1 item
  211. PDK-1 1 item
  212. Prk 1 item
  213. Trx 1 item
  214. Neurokinin receptor 1 item
  215. HSP70 1 item
  216. ICAM 1 item
  217. ITK 1 item
  218. Rho 1 item
  219. Aryl hydrocarbon receptors (AHRs) 1 item
  220. Ubiquitin E3 Ligases 1 item
  221. DCLK2 1 item
  222. integrase 1 item
  223. NOS 1 item
  224. GPR3 1 item
  225. Adenosine Deaminases 1 item
  226. mitochondrial pyruvate carrier (MPC) 1 item
  227. DNA gyrase 1 item
  228. prolactin secretion 1 item
  229. gonadotropin release 1 item
  230. DprE 1 item
  231. Vitamin D 1 item
  232. Flk1 1 item
  233. SAPK 1 item
  234. p21 1 item
  235. Prostaglandin synthesis 1 item
  236. glutamate release 1 item
  237. Aromatases 1 item
  238. 5-HT 1 item
  239. MCL1 1 item
  240. Bcl-w 1 item
  241. ACE 1 item
  242. MST 1 item
  243. PPK 1 item
  244. c-Syk 1 item
  245. CDK1/CyclinB 1 item
  246. Tph 1 item
  247. reverse transcriptase 1 item
  248. Cholesterol absorption 1 item
  249. Substance P/NK1 Receptor 1 item
  250. gp120/CD4 1 item
  251. PTEN 1 item
  252. NS3/4a Proteases 1 item
  253. p90 S6K 1 item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acute Disseminated Candidiasis 1 item
  3. Acute Lung Injury 1 item
  4. Acute Myeloid Leukemia 7item
  5. Adrenocortical Carcinoma 1 item
  6. Advanced Renal Cell Carcinoma 1 item
  7. Autoimmune Diseases 1 item
  8. Biliary Cancer 1 item
  9. Bladder Cancer 2item
  10. Bladder Carcinoma 1 item
  11. Bladder Diseases 1 item
  12. Brain Injuries Studies 1 item
  13. Breast Cancer 39item
  14. Cancer 195item
  15. Candida Peritonitis 1 item
  16. Candidemia 1 item
  17. Cervical Cancer 2item
  18. Chronic Lymphocytic Leukemia 2item
  19. Clear Cell Renal Cell Carcinoma 1 item
  20. Colon Cancer 13item
  21. Colon Carcinoma 5item
  22. Colorectal Cancer 18item
  23. Diabetes 1 item
  24. Epilepsy 3item
  25. Fungal Infection 1 item
  26. Glioblastoma 10item
  27. Glioma 7item
  28. HCV 1 item
  29. Heart Failure 3item
  30. Hepatic Cancer 1 item
  31. Hepatitis C 2item
  32. Hepatocellular Carcinoma 2item
  33. HIV 7item
  34. HIV Infections 4item
  35. Hypercholesterolemia 2item
  36. Inflammatory Diseases 9item
  37. Leukemia 11item
  38. Liver Cancer 1 item
  39. Lung Cancer 13item
  40. Lung Carcinoma 2item
  41. Lymphoma 13item
  42. Medulloblastoma 1 item
  43. Melanoma 16item
  44. Mixed Lineage Leukemia 1 item
  45. Multiple Myeloma 6item
  46. Myelofibrosis 1 item
  47. Myeloma 3item
  48. Neuroblastoma 2item
  49. Non-small Cell Lung Cancer 10item
  50. Non-small Cell Lung Carcinoma 1 item
  51. Osteoporosis 1 item
  52. Ovarian Cancer 14item
  53. Pancreatic Cancer 19item
  54. Pancreatic Carcinoma 1 item
  55. Pentacyclic Triterpenoid 1 item
  56. Prostate Cancer 21item
  57. Psoriasis 1 item
  58. Pulmonary Arterial Hypertension 1 item
  59. Renal Cancer 3item
  60. Renal Cell Carcinoma 4item
  61. Rheumatoid Arthritis 6item
  62. Schizophrenia 1 item
  63. Sleep Disorders 1 item
  64. Squamous Cell Carcinoma 1 item
  65. Testicular Cancer 1 item
  66. Thyroid Cancer 4item
  67. Tuberculosis 4item
  68. Type 2 Diabetes 7item