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Search results for: 'mcl1 in 1'

Items 491-500 of 1534

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  1. Trametinib DMSO solvate
    A3887 Trametinib DMSO solvate
     1 Citation
    Target: MEK
    Summary: Allosteric MEK1/MEK2 kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥11.2 mg/mL
  2. VCH-916
    A3909 VCH-916
    Summary: HCV NS5B polymerase inhibitor
      Soluble in DMSO
  3. Voreloxin Hydrochloride
    A3925 Voreloxin Hydrochloride
    Summary: Antineoplastic naphthyridine analogue
      Soluble in DMSO
  4. XMD17-109
    A3942 XMD17-109
    Target: ERK
    Summary: ERK-5 inhibitor
      ≥31.95 mg/mL
  5. Acetyl-Calpastatin (184-210) (human)
    A4410 Acetyl-Calpastatin (184-210) (human)
    Summary: Calpain I/II inhibitor
      Soluble to 5 mg/mL
  6. Cryptotanshinone
    N1843 Cryptotanshinone
    Summary: STAT3/AChE inhibitor
      insoluble in H2O; insoluble in EtOH; ≥4.23 mg/mL
  7. PCI-32765 (Ibrutinib)
    A3001 PCI-32765 (Ibrutinib)
     4 Citation
    Summary: Bruton's tyrosine kinase (BTK) inhibitor
      ≥22.02 mg/mL
  8. MDV3100 (Enzalutamide)
    A3003 MDV3100 (Enzalutamide)
     12 Citation
    Target: Androgen Receptors
    Summary: Androgen receptor antagonist
      ≥23.22 mg/mL
  9. Vemurafenib (PLX4032, RG7204)
    A3004 Vemurafenib (PLX4032, RG7204)
     9 Citation
    Target: Raf
    Summary: BRAF kinase inhibitor
      ≥24.5 mg/mL
  10. RO4929097
    A4005 RO4929097
     1 Citation
    Summary: γ secretase inhibitor
      ≥23.47 mg/mL

Items 491-500 of 1534

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Category
  1. Proteases 76item
  2. Apoptosis 81item
  3. Chromatin/Epigenetics 114item
  4. Metabolism 82item
  5. MAPK Signaling 55item
  6. Tyrosine Kinase 108item
  7. DNA Damage/DNA Repair 69item
  8. PI3K/Akt/mTOR Signaling 51item
  9. Microbiology & Virology 69item
  10. Cell Cycle/Checkpoint 76item
  11. Ubiquitination/ Proteasome 17item
  12. JAK/STAT Signaling 36item
  13. TGF-β / Smad Signaling 32item
  14. Angiogenesis 21item
  15. GPCR/G protein 215item
  16. Stem Cell 42item
  17. Membrane Transporter/Ion Channel 100item
  18. Cancer Biology 3item
  19. Endocrinology and Hormones 41item
  20. Neuroscience 135item
  21. Obesity, Appetite Control & Diabetes 1 item
  22. Peptide Inhibitors and Substrate 1 item
  23. Other Signal Transduction 18item
  24. Others 177item
  25. Immunology/Inflammation 31item
  26. Cardiovascular 16item
  27. Vitamin D Related 9item
  28. NF-κB 2item
  29. Autophagy 2item
  30. Metabolic Enzyme/Protease 30item
  31. Alkaloids 1 item
  32. Anti-infection 10item
  33. Cell Cycle/DNA Damage 2item
  34. Neuronal Signaling 2item
  35. Terpenoids and Glycosides 1 item
Specificity
  1. Selective 326item
  2. Non-Selective 2item
Reversibility
  1. Reversible 18item
  2. Irreversible 8item
Target
  1. Caspases 6item
  2. Cyclin-Dependent Kinases 15item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 2item
  5. Cathepsins 3item
  6. Histone Deacetylases (HDACs) 11item
  7. Inhibitor of apoptosis proteins (IAP) 1 item
  8. Akt 5item
  9. Bcl-2 8item
  10. PI3K 11item
  11. CXCR 1 item
  12. Raf 7item
  13. Aurora Kinases 6item
  14. Bcl-xl 2item
  15. CSF-1R 1 item
  16. Gap Junctions 2item
  17. MDM2 2item
  18. EZH2 3item
  19. mTOR 11item
  20. Bromodomains 3item
  21. AP-1 3item
  22. MMP 8item
  23. Androgen Receptors 4item
  24. Acyl coenzyme A: cholesterol acyltransferases 1 item
  25. FLT3 10item
  26. GSK-3 3item
  27. Factor Xa 1 item
  28. LPA Receptors 3item
  29. PLK 6item
  30. Chk 4item
  31. VEGFR 22item
  32. PDGFR 14item
  33. c-Kit 6item
  34. RET 3item
  35. IRAK 3item
  36. Bromodomain-containing proteins(BRDs) 1 item
  37. Phosphodiesterases (PDEs) 1 item
  38. Mcl-1 7item
  39. p38 4item
  40. PKB 1 item
  41. JNK 1 item
  42. SGK 2item
  43. Bcr-Abl 7item
  44. MEK 7item
  45. PORCN 1 item
  46. DOT1L 1 item
  47. FGFR 4item
  48. Insulin-like growth factor receptors(IGFRs) 1 item
  49. CGRP receptors 1 item
  50. Pim 2item
  51. Liver X receptors (LXRs) 1 item
  52. Glucagon-like peptide 1 (GLP-1) receptors 2item
  53. Sir2-like Family Deacetylases (Sirtuins) 3item
  54. Voltage-gated Sodium (NaV) Channels 1 item
  55. Deubiquitinating enzymes (DUBs) 2item
  56. PP1 1 item
  57. PP2A 1 item
  58. Smoothened 2item
  59. Eukaryotic elongation factors 1 item
  60. MET 1 item
  61. Src 9item
  62. Trk Receptors 3item
  63. Aminopeptidases 3item
  64. NMDA Receptors 1 item
  65. STAT 4item
  66. Microtubules/Tubulins 4item
  67. Estrogen and Related Receptors 2item
  68. EGFR 2item
  69. Reverse Transcriptases 1 item
  70. ROCK 3item
  71. BTK 1 item
  72. RIP kinases 1 item
  73. PAK 1 item
  74. PD-1/PD-L1 interaction 1 item
  75. Hypoxia Inducible Factors (HIFs) 1 item
  76. BMP and Other Activin Receptors 1 item
  77. JAK 9item
  78. p300 1 item
  79. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  80. Syk 3item
  81. Progesterone Receptors 1 item
  82. EZH1 1 item
  83. DNA-PK 3item
  84. HSP90 1 item
  85. AMPK 1 item
  86. Gutathione S-transferase 1 item
  87. CCR 2item
  88. eIF4E/eIF3G interaction 1 item
  89. TNKS 1 item
  90. Topoisomerases 5item
  91. Cytochrome P450 (CYP450) 4item
  92. Ferroptosis 1 item
  93. Toll-like receptors (TLRs) 3item
  94. Actin 1 item
  95. DNA Methyltransferases 2item
  96. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  97. ERK 3item
  98. HMG-CoA Reductases 1 item
  99. Vacuolar-type ATPase 1 item
  100. c-MET 3item
  101. BMI-1 1 item
  102. PKC 6item
  103. Calpains 2item
  104. M1 Receptors 1 item
  105. HCV Proteases 1 item
  106. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  107. Protease-Activated Receptors 2item
  108. RAD51 1 item
  109. USP 1 item
  110. 5-HT2 Receptors 3item
  111. LRRK2 2item
  112. Calcium chelator 1 item
  113. DGAT 2item
  114. Insulin and Insulin-like Receptors 2item
  115. PARP 5item
  116. CB1 Receptors 2item
  117. ALK 1 item
  118. Sphingosine kinases (SphKs) 2item
  119. Trypsin 1 item
  120. Chymotrypsin 1 item
  121. Kallikrein 1 item
  122. Trypsinogen 1 item
  123. Monocarboxylate transporters (MCTs) 2item
  124. PKG 1 item
  125. PKA 4item
  126. GPR30 1 item
  127. HIV-1 gp120 1 item
  128. D2 Receptors 1 item
  129. TBK1 1 item
  130. MARK1 1 item
  131. NUAK1 1 item
  132. Lactate Dehydrogenases (LDH) 1 item
  133. MK2 2item
  134. Tie-2 2item
  135. Free Fatty Acid Receptors 1 item
  136. phosphatases 1 item
  137. Autophagy 3item
  138. ATM/ATR 3item
  139. COX 6item
  140. YAP 1 item
  141. CK1 2item
  142. CK2 1 item
  143. HIV Integrases 1 item
  144. Cryptochromes 1 item
  145. G-quadruplexes 1 item
  146. NAT10 1 item
  147. Nampt 1 item
  148. P2X Receptors 1 item
  149. Glutaminases 1 item
  150. Carbonic Anhydrases 2item
  151. Ron 1 item
  152. BLM 1 item
  153. HSV 2item
  154. NADPH Oxidases 1 item
  155. Calcium-activated chloride channels (CaCC) 1 item
  156. GPR35 1 item
  157. Aldehyde Dehydrogenases 1 item
  158. Synthases/Synthetases 1 item
  159. MAGL 1 item
  160. c-Fyn 1 item
  161. Leukotriene and Related Receptors 1 item
  162. Histamine H1 Receptors 1 item
  163. RAR/RXR 1 item
  164. Inositol-requiring enzyme 1 (IRE1) 1 item
  165. SETD7 1 item
  166. Na /K /Cl- Symporters (NKCCs) 1 item
  167. TRP Channel 2item
  168. RNA Polymerases 1 item
  169. Norepinephrine transporter 1 item
  170. 5-HT Transporters 1 item
  171. Guanylyl Cyclases 1 item
  172. Histone Demethylases 1 item
  173. MNK 2item
  174. NO Donors / Precursors 1 item
  175. CB2 Receptors 1 item
  176. HIV-1 reverse transcriptase 1 item
  177. IL Receptors 1 item
  178. 15-lipoxygenases 1 item
  179. Insulin Receptors 1 item
  180. IRG-1R 1 item
  181. eEF-2 1 item
  182. Inward Rectifier Potassium (Kir) Channels 1 item
  183. CRTH2 1 item
  184. Nuclear Receptors 1 item
  185. ZAP-70 1 item
  186. Angiotensin AT1 Receptors 2item
  187. Protein Arginine Methyltransferases 1 item
  188. Na /Ca2 Exchangers (NCXs) 1 item
  189. Ubiquitin-activating Enzyme E1 1 item
  190. Glucagon Receptors 1 item
  191. PP4 1 item
  192. c-RET 1 item
  193. Nonstructural protein 5B (NS5B) 1 item
  194. guanylyl cyclase 1 item
  195. ETA Receptors 2item
  196. ETB Receptors 1 item
  197. p70 rsk 3item
  198. voltage-gated chloride channels 1 item
  199. 5-HT1 Receptor 1 item
  200. VEGFR3/FLT4 1 item
  201. NTRK1/TRKA 1 item
  202. CSF-1R/c-Fms 1 item
  203. Menin-MLL 2item
  204. Tryptophan hydroxylases (TPH) 1 item
  205. NMPRTase 1 item
  206. Bfl-1 1 item
  207. KDR 1 item
  208. Fyn kinase 1 item
  209. dCTP Pyrophosphatases 1 item
  210. Protein polybromo-1 1 item
  211. SMARCA4 1 item
  212. SMARCA2 1 item
  213. p53 4item
  214. metalloprotease 1 item
  215. Antifungal 1 item
  216. 5-HT receptors 1 item
  217. sodium channel 1 item
  218. c-Fms tyrosine kinase 1 item
  219. PAR 1 item
  220. Smoothened receptor 1 item
  221. PPAR 1 item
  222. USP1/USF1 complex 1 item
  223. IKK 1 item
  224. TRPV 1 item
  225. Ftase 1 item
  226. Elastases 1 item
  227. ATP synthase 1 item
  228. Vitamin D receptors (VDRs) 1 item
  229. Antibiotic 2item
  230. Mer tyrosine kinase 1 item
  231. Hec1 1 item
  232. Stem Cell Differentiation 1 item
  233. PP2A/Nkd interaction 1 item
  234. HMGCR 1 item
  235. HIV 1 item
  236. TRPA 1 item
  237. PDK-1 1 item
  238. telomerase 1 item
  239. Prk 1 item
  240. Trx 1 item
  241. Neurokinin receptor 1 item
  242. HSP70 1 item
  243. ICAM 1 item
  244. ITK 1 item
  245. NOD1 1 item
  246. Rho 1 item
  247. Aryl hydrocarbon receptors (AHRs) 1 item
  248. Ubiquitin E3 Ligases 1 item
  249. DCLK2 1 item
  250. integrase 1 item
  251. L3MBTL 1 item
  252. NOS 1 item
  253. GPR3 1 item
  254. Lck 1 item
  255. Adenosine Deaminases 1 item
  256. mitochondrial pyruvate carrier (MPC) 1 item
  257. DNA gyrase 1 item
  258. prolactin secretion 1 item
  259. gonadotropin release 1 item
  260. DprE 1 item
  261. Vitamin D 1 item
  262. Flk1 1 item
  263. SAPK 1 item
  264. p21 1 item
  265. Prostaglandin synthesis 1 item
  266. glutamate release 1 item
  267. Aromatases 1 item
  268. 5-HT 1 item
  269. Octamer-binding transcription factor 4 (Oct4) 1 item
  270. MCL1 1 item
  271. Bcl-w 1 item
  272. ACE 1 item
  273. MST 1 item
  274. PPK 1 item
  275. c-Syk 1 item
  276. CDK1/CyclinB 1 item
  277. Tph 1 item
  278. reverse transcriptase 1 item
  279. Cholesterol absorption 1 item
  280. Substance P/NK1 Receptor 1 item
  281. gp120/CD4 1 item
  282. ATM 1 item
  283. PTEN 1 item
  284. NS3/4a Proteases 1 item
  285. p90 S6K 1 item
Reported Experiments
  1. Animal Experiments 404item
  2. Cell Experiments 330item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acute Disseminated Candidiasis 1 item
  3. Acute Lung Injury 1 item
  4. Acute Myeloid Leukemia 8item
  5. Adrenocortical Carcinoma 1 item
  6. Advanced Renal Cell Carcinoma 1 item
  7. Autoimmune Diseases 1 item
  8. Biliary Cancer 1 item
  9. Bladder Cancer 2item
  10. Bladder Carcinoma 1 item
  11. Bladder Diseases 1 item
  12. Brain Injuries Studies 1 item
  13. Breast Cancer 43item
  14. Cancer 211item
  15. Candida Peritonitis 1 item
  16. Candidemia 1 item
  17. Cervical Cancer 2item
  18. Chronic Lymphocytic Leukemia 2item
  19. Clear Cell Renal Cell Carcinoma 1 item
  20. Colon Cancer 15item
  21. Colon Carcinoma 5item
  22. Colorectal Cancer 20item
  23. Diabetes 3item
  24. Epilepsy 3item
  25. Fungal Infection 1 item
  26. Glioblastoma 11item
  27. Glioma 7item
  28. HCV 1 item
  29. Heart Failure 3item
  30. Hepatic Cancer 1 item
  31. Hepatitis C 2item
  32. Hepatocellular Carcinoma 2item
  33. HIV 8item
  34. HIV Infections 4item
  35. Hypercholesterolemia 2item
  36. Inflammatory Diseases 9item
  37. Leukemia 12item
  38. Liver Cancer 1 item
  39. Lung Cancer 14item
  40. Lung Carcinoma 2item
  41. Lymphoma 15item
  42. Medulloblastoma 1 item
  43. Melanoma 16item
  44. Mixed Lineage Leukemia 1 item
  45. Multiple Myeloma 7item
  46. Myelofibrosis 1 item
  47. Myeloma 3item
  48. Neuroblastoma 2item
  49. Non-small Cell Lung Cancer 10item
  50. Non-small Cell Lung Carcinoma 1 item
  51. Osteoporosis 1 item
  52. Ovarian Cancer 14item
  53. Pancreatic Cancer 19item
  54. Pancreatic Carcinoma 1 item
  55. Pentacyclic Triterpenoid 1 item
  56. Prostate Cancer 25item
  57. Psoriasis 1 item
  58. Pulmonary Arterial Hypertension 1 item
  59. Renal Cancer 3item
  60. Renal Cell Carcinoma 4item
  61. Rheumatoid Arthritis 6item
  62. Schizophrenia 1 item
  63. Sleep Disorders 1 item
  64. Squamous Cell Carcinoma 1 item
  65. Testicular Cancer 1 item
  66. Thyroid Cancer 4item
  67. Tuberculosis 4item
  68. Type 2 Diabetes 8item