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  • Search results for: 'mcl1 in 1'

Search results for: 'mcl1 in 1'

Items 71-80 of 211

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  1. Vemurafenib (PLX4032, RG7204)
    A3004 Vemurafenib (PLX4032, RG7204)
     9 Citation
    Target: Raf
    Summary: BRAF kinase inhibitor
      ≥24.5 mg/mL
  2. RO4929097
    A4005 RO4929097
     1 Citation
    Summary: γ secretase inhibitor
      ≥23.47 mg/mL
  3. WP1066
    A4140 WP1066
    Target: STAT|JAK
    Summary: JAK2/STAT3 inhibitor,cell-permeable
      insoluble in H2O; ≥17.8 mg/mL
  4. EPZ005687
    A4171 EPZ005687
     2 Citation
    Target: EZH2
    Summary: EZH2 inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥3.86 mg/mL
  5. AR-42 (OSU-HDAC42)
    A4104 AR-42 (OSU-HDAC42)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,novel and potent
      insoluble in EtOH; insoluble in H2O; ≥15.62 mg/mL
  6. Hesperadin
    A4118 Hesperadin
     1 Citation
    Target: Aurora Kinases
    Summary: Aurora B kinase inhibitor
      ≥25.85 mg/mL
  7. Ketoconazole
    A4316 Ketoconazole
    Target: Cytochrome P450 (CYP450)
    Summary: Inhibitor of cyclosporine oxidase and testosterone 6 beta-hydroxylase
      ≥23.4 mg/mL
  8. U-104
    A4358 U-104
    Target: Carbonic Anhydrases
    Summary: CAIX inhibitor
      insoluble in H2O; ≥11.5 mg/mL
  9. NLG919
    A4373 NLG919
     1 Citation
    Summary: Potent IDO pathway inhibitor
      insoluble in H2O; insoluble in EtOH; ≥47.7 mg/mL
  10. FK866 (APO866)
    A4381 FK866 (APO866)
     1 Citation
    Target: Nampt
    Summary: NAMPT inhibitor, non-competitive, highly specific
      insoluble in H2O; ≥19.6 mg/mL

Items 71-80 of 211

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  1. Category Signaling Pathways Remove This Item
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Category
  1. Proteases 9item
  2. Apoptosis 20item
  3. Chromatin/Epigenetics 29item
  4. Metabolism 6item
  5. MAPK Signaling 14item
  6. Tyrosine Kinase 33item
  7. DNA Damage/DNA Repair 20item
  8. PI3K/Akt/mTOR Signaling 14item
  9. Microbiology & Virology 3item
  10. Cell Cycle/Checkpoint 31item
  11. Ubiquitination/ Proteasome 7item
  12. JAK/STAT Signaling 8item
  13. TGF-β / Smad Signaling 6item
  14. Angiogenesis 2item
  15. GPCR/G protein 7item
  16. Stem Cell 12item
  17. Membrane Transporter/Ion Channel 2item
  18. Endocrinology and Hormones 5item
  19. Neuroscience 7item
  20. Others 13item
  21. Immunology/Inflammation 4item
Specificity
  1. Selective 168item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 9item
  2. Irreversible 4item
Target
  1. Caspases 2item
  2. Cyclin-Dependent Kinases 11item
  3. Proteasome 1 item
  4. Histone Deacetylases (HDACs) 7item
  5. Akt 5item
  6. Bcl-2 7item
  7. PI3K 7item
  8. CXCR 1 item
  9. Raf 7item
  10. Aurora Kinases 4item
  11. Bcl-xl 2item
  12. CSF-1R 1 item
  13. MDM2 1 item
  14. EZH2 3item
  15. mTOR 7item
  16. Bromodomains 1 item
  17. AP-1 1 item
  18. MMP 3item
  19. Androgen Receptors 3item
  20. FLT3 5item
  21. LPA Receptors 1 item
  22. PLK 6item
  23. Chk 2item
  24. VEGFR 20item
  25. PDGFR 11item
  26. c-Kit 4item
  27. RET 3item
  28. Bromodomain-containing proteins(BRDs) 1 item
  29. Mcl-1 5item
  30. p38 1 item
  31. SGK 2item
  32. Bcr-Abl 3item
  33. MEK 5item
  34. PORCN 1 item
  35. DOT1L 1 item
  36. FGFR 3item
  37. Insulin-like growth factor receptors(IGFRs) 1 item
  38. Pim 1 item
  39. Liver X receptors (LXRs) 1 item
  40. Sir2-like Family Deacetylases (Sirtuins) 2item
  41. Deubiquitinating enzymes (DUBs) 2item
  42. PP1 1 item
  43. PP2A 1 item
  44. Smoothened 2item
  45. MET 1 item
  46. Src 5item
  47. Trk Receptors 2item
  48. Aminopeptidases 1 item
  49. STAT 3item
  50. Microtubules/Tubulins 4item
  51. Estrogen and Related Receptors 1 item
  52. EGFR 2item
  53. PAK 1 item
  54. Hypoxia Inducible Factors (HIFs) 1 item
  55. BMP and Other Activin Receptors 1 item
  56. JAK 4item
  57. p300 1 item
  58. Syk 1 item
  59. EZH1 1 item
  60. DNA-PK 2item
  61. HSP90 1 item
  62. Gutathione S-transferase 1 item
  63. CCR 1 item
  64. eIF4E/eIF3G interaction 1 item
  65. TNKS 1 item
  66. Topoisomerases 3item
  67. Cytochrome P450 (CYP450) 2item
  68. ERK 1 item
  69. Vacuolar-type ATPase 1 item
  70. c-MET 3item
  71. BMI-1 1 item
  72. PKC 4item
  73. Calpains 1 item
  74. RAD51 1 item
  75. 5-HT2 Receptors 2item
  76. Calcium chelator 1 item
  77. PARP 3item
  78. ALK 1 item
  79. Sphingosine kinases (SphKs) 2item
  80. Monocarboxylate transporters (MCTs) 1 item
  81. PKG 1 item
  82. PKA 3item
  83. GPR30 1 item
  84. D2 Receptors 1 item
  85. MK2 1 item
  86. Tie-2 1 item
  87. Autophagy 3item
  88. ATM/ATR 2item
  89. COX 2item
  90. YAP 1 item
  91. CK1 1 item
  92. CK2 1 item
  93. G-quadruplexes 1 item
  94. Nampt 1 item
  95. P2X Receptors 1 item
  96. Glutaminases 1 item
  97. Carbonic Anhydrases 1 item
  98. Ron 1 item
  99. BLM 1 item
  100. Synthases/Synthetases 1 item
  101. MAGL 1 item
  102. Inositol-requiring enzyme 1 (IRE1) 1 item
  103. RNA Polymerases 1 item
  104. Norepinephrine transporter 1 item
  105. 5-HT Transporters 1 item
  106. Guanylyl Cyclases 1 item
  107. Histone Demethylases 1 item
  108. MNK 1 item
  109. HIV-1 reverse transcriptase 1 item
  110. Insulin Receptors 1 item
  111. IRG-1R 1 item
  112. eEF-2 1 item
  113. ZAP-70 1 item
  114. Protein Arginine Methyltransferases 1 item
  115. PP4 1 item
  116. p70 rsk 2item
  117. VEGFR3/FLT4 1 item
  118. NTRK1/TRKA 1 item
  119. CSF-1R/c-Fms 1 item
  120. NMPRTase 1 item
  121. Bfl-1 1 item
  122. KDR 1 item
  123. p53 2item
  124. Smoothened receptor 1 item
  125. Hec1 1 item
  126. PDK-1 1 item
  127. Prk 1 item
  128. Trx 1 item
  129. HSP70 1 item
  130. Adenosine Deaminases 1 item
  131. Flk1 1 item
  132. MCL1 1 item
  133. Bcl-w 1 item
  134. PPK 1 item
  135. c-Syk 1 item
  136. CDK1/CyclinB 1 item
  137. Substance P/NK1 Receptor 1 item
Reported Experiments
  1. Animal Experiments 195item
  2. Cell Experiments 134item