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  • Search results for: 'mcl1 in 1'

Search results for: 'mcl1 in 1'

Items 81-90 of 326

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  1. MK-2461
    A8476 MK-2461
    Target: FLT3|PDGFR|MET|Ron
    Summary: C-Met (WT/mutants) inhibitor
      ≥24.8 mg/mL
  2. R406
    A8546 R406
     1 Citation
    Target: Syk
    Summary: SYK inhibitor,potent and ATP-competitive
      ≥31.45 mg/mL
  3. CP-466722
    A8625 CP-466722
    Target: ATM
    Summary: ATM inhibitor,potent and reversible
      ≥4.36 mg/mL
  4. Inauhzin
    B3272 Inauhzin
    Target: Sir2-like Family Deacetylases (Sirtuins)
    Summary: SIRT1 inhibitor
      ≥23.5 mg/mL
  5. WYE-125132 (WYE-132)
    B1642 WYE-125132 (WYE-132)
    Target: mTOR
    Summary: ATP-competitive mTOR inhibitor, highly potent
      insoluble in EtOH; insoluble in H2O; ≥13 mg/mL
  6. Valproic acid
    B1251 Valproic acid
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC1 inhibitor
      ≥12.35 mg/mL
  7. Torin 2
    B1640 Torin 2
     1 Citation
    Target: mTOR|DNA-PK|ATM/ATR
    Summary: MTOR inhibitor,highly potent and selective
      ≥21.6 mg/mL
  8. Ambrisentan
    B2075 Ambrisentan
    Target: ETA Receptors
    Summary: ETA-receptor antagonist
      insoluble in H2O; ≥18.92 mg/mL
  9. SR-3677
    B1294 SR-3677
    Target: ROCK
    Summary: Rho Kinase (ROCK-II) inhibitor
      Soluble in DMSO
  10. BS-181
    A3266 BS-181
    Target: Cyclin-Dependent Kinases
    Summary: CDK7 inhibitor,highly selective
      Soluble in DMSO

Items 81-90 of 326

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Category
  1. Proteases 29item
  2. Apoptosis 24item
  3. Chromatin/Epigenetics 37item
  4. Metabolism 16item
  5. MAPK Signaling 18item
  6. Tyrosine Kinase 44item
  7. DNA Damage/DNA Repair 23item
  8. PI3K/Akt/mTOR Signaling 16item
  9. Microbiology & Virology 15item
  10. Cell Cycle/Checkpoint 32item
  11. Ubiquitination/ Proteasome 6item
  12. JAK/STAT Signaling 10item
  13. TGF-β / Smad Signaling 10item
  14. Angiogenesis 3item
  15. GPCR/G protein 19item
  16. Stem Cell 15item
  17. Membrane Transporter/Ion Channel 8item
  18. Endocrinology and Hormones 9item
  19. Neuroscience 16item
  20. Obesity, Appetite Control & Diabetes 1 item
  21. Other Signal Transduction 2item
  22. Others 25item
  23. Immunology/Inflammation 10item
  24. Cardiovascular 1 item
Reversibility
  1. Reversible 13item
  2. Irreversible 5item
Target
  1. Caspases 5item
  2. Cyclin-Dependent Kinases 12item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 1 item
  5. Cathepsins 3item
  6. Histone Deacetylases (HDACs) 8item
  7. Inhibitor of apoptosis proteins (IAP) 1 item
  8. Akt 1 item
  9. Bcl-2 6item
  10. PI3K 8item
  11. CXCR 1 item
  12. Raf 6item
  13. Aurora Kinases 5item
  14. Bcl-xl 2item
  15. CSF-1R 1 item
  16. Gap Junctions 1 item
  17. MDM2 1 item
  18. EZH2 3item
  19. mTOR 7item
  20. Bromodomains 1 item
  21. AP-1 3item
  22. MMP 8item
  23. Androgen Receptors 4item
  24. Acyl coenzyme A: cholesterol acyltransferases 1 item
  25. FLT3 9item
  26. GSK-3 2item
  27. Factor Xa 1 item
  28. LPA Receptors 1 item
  29. PLK 4item
  30. Chk 4item
  31. VEGFR 17item
  32. PDGFR 11item
  33. c-Kit 4item
  34. RET 2item
  35. IRAK 2item
  36. Bromodomain-containing proteins(BRDs) 1 item
  37. Mcl-1 5item
  38. p38 3item
  39. PKB 1 item
  40. SGK 2item
  41. Bcr-Abl 5item
  42. MEK 6item
  43. PORCN 1 item
  44. DOT1L 1 item
  45. FGFR 3item
  46. Insulin-like growth factor receptors(IGFRs) 1 item
  47. CGRP receptors 1 item
  48. Pim 2item
  49. Glucagon-like peptide 1 (GLP-1) receptors 2item
  50. Sir2-like Family Deacetylases (Sirtuins) 2item
  51. Deubiquitinating enzymes (DUBs) 1 item
  52. PP1 1 item
  53. PP2A 1 item
  54. Smoothened 2item
  55. Eukaryotic elongation factors 1 item
  56. MET 1 item
  57. Src 5item
  58. Trk Receptors 3item
  59. Aminopeptidases 2item
  60. STAT 2item
  61. Microtubules/Tubulins 4item
  62. EGFR 2item
  63. Reverse Transcriptases 1 item
  64. ROCK 2item
  65. BTK 1 item
  66. RIP kinases 1 item
  67. PAK 1 item
  68. Hypoxia Inducible Factors (HIFs) 1 item
  69. BMP and Other Activin Receptors 1 item
  70. JAK 5item
  71. p300 1 item
  72. Syk 3item
  73. Progesterone Receptors 1 item
  74. EZH1 1 item
  75. DNA-PK 2item
  76. HSP90 1 item
  77. AMPK 1 item
  78. Gutathione S-transferase 1 item
  79. CCR 2item
  80. eIF4E/eIF3G interaction 1 item
  81. TNKS 1 item
  82. Topoisomerases 3item
  83. Cytochrome P450 (CYP450) 3item
  84. Ferroptosis 1 item
  85. Toll-like receptors (TLRs) 2item
  86. Actin 1 item
  87. DNA Methyltransferases 1 item
  88. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  89. ERK 3item
  90. HMG-CoA Reductases 1 item
  91. Vacuolar-type ATPase 1 item
  92. c-MET 3item
  93. BMI-1 1 item
  94. PKC 3item
  95. Calpains 2item
  96. HCV Proteases 1 item
  97. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  98. Protease-Activated Receptors 1 item
  99. USP 1 item
  100. 5-HT2 Receptors 3item
  101. LRRK2 2item
  102. Calcium chelator 1 item
  103. DGAT 2item
  104. Insulin and Insulin-like Receptors 2item
  105. PARP 2item
  106. CB1 Receptors 1 item
  107. ALK 1 item
  108. Sphingosine kinases (SphKs) 1 item
  109. Trypsin 1 item
  110. Chymotrypsin 1 item
  111. Kallikrein 1 item
  112. Trypsinogen 1 item
  113. Monocarboxylate transporters (MCTs) 1 item
  114. GPR30 1 item
  115. HIV-1 gp120 1 item
  116. D2 Receptors 1 item
  117. TBK1 1 item
  118. MARK1 1 item
  119. NUAK1 1 item
  120. Lactate Dehydrogenases (LDH) 1 item
  121. MK2 2item
  122. Tie-2 2item
  123. Free Fatty Acid Receptors 1 item
  124. phosphatases 1 item
  125. Autophagy 2item
  126. ATM/ATR 3item
  127. COX 4item
  128. YAP 1 item
  129. CK1 1 item
  130. Cryptochromes 1 item
  131. G-quadruplexes 1 item
  132. NAT10 1 item
  133. Nampt 1 item
  134. P2X Receptors 1 item
  135. Glutaminases 1 item
  136. Carbonic Anhydrases 2item
  137. Ron 1 item
  138. BLM 1 item
  139. HSV 1 item
  140. Calcium-activated chloride channels (CaCC) 1 item
  141. GPR35 1 item
  142. Aldehyde Dehydrogenases 1 item
  143. Synthases/Synthetases 1 item
  144. MAGL 1 item
  145. c-Fyn 1 item
  146. Leukotriene and Related Receptors 1 item
  147. Histamine H1 Receptors 1 item
  148. Inositol-requiring enzyme 1 (IRE1) 1 item
  149. SETD7 1 item
  150. TRP Channel 2item
  151. RNA Polymerases 1 item
  152. Norepinephrine transporter 1 item
  153. 5-HT Transporters 1 item
  154. Guanylyl Cyclases 1 item
  155. Histone Demethylases 1 item
  156. MNK 1 item
  157. NO Donors / Precursors 1 item
  158. CB2 Receptors 1 item
  159. HIV-1 reverse transcriptase 1 item
  160. IL Receptors 1 item
  161. 15-lipoxygenases 1 item
  162. Insulin Receptors 1 item
  163. IRG-1R 1 item
  164. eEF-2 1 item
  165. Inward Rectifier Potassium (Kir) Channels 1 item
  166. CRTH2 1 item
  167. Nuclear Receptors 1 item
  168. ZAP-70 1 item
  169. Angiotensin AT1 Receptors 2item
  170. Protein Arginine Methyltransferases 1 item
  171. Na /Ca2 Exchangers (NCXs) 1 item
  172. Glucagon Receptors 1 item
  173. PP4 1 item
  174. c-RET 1 item
  175. Nonstructural protein 5B (NS5B) 1 item
  176. ETA Receptors 2item
  177. ETB Receptors 1 item
  178. p70 rsk 1 item
  179. Protein polybromo-1 1 item
  180. SMARCA4 1 item
  181. SMARCA2 1 item
  182. c-Fms tyrosine kinase 1 item
  183. IKK 1 item
  184. Ftase 1 item
  185. Elastases 1 item
  186. telomerase 1 item
  187. ITK 1 item
  188. NOD1 1 item
  189. DCLK2 1 item
  190. Lck 1 item
  191. Aromatases 1 item
  192. MCL1 1 item
  193. Bcl-w 1 item
  194. MST 1 item
  195. Substance P/NK1 Receptor 1 item
  196. gp120/CD4 1 item
  197. ATM 1 item
Reported Experiments
  1. Animal Experiments 275item
  2. Cell Experiments 191item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acute Disseminated Candidiasis 1 item
  3. Acute Lung Injury 1 item
  4. Acute Myeloid Leukemia 8item
  5. Adrenocortical Carcinoma 1 item
  6. Advanced Renal Cell Carcinoma 1 item
  7. Autoimmune Diseases 1 item
  8. Biliary Cancer 1 item
  9. Bladder Cancer 2item
  10. Bladder Carcinoma 1 item
  11. Bladder Diseases 1 item
  12. Brain Injuries Studies 1 item
  13. Breast Cancer 43item
  14. Cancer 168item
  15. Candida Peritonitis 1 item
  16. Candidemia 1 item
  17. Cervical Cancer 2item
  18. Chronic Lymphocytic Leukemia 2item
  19. Clear Cell Renal Cell Carcinoma 1 item
  20. Colon Cancer 14item
  21. Colon Carcinoma 5item
  22. Colorectal Cancer 19item
  23. Diabetes 3item
  24. Epilepsy 2item
  25. Fungal Infection 1 item
  26. Glioblastoma 11item
  27. Glioma 7item
  28. Hepatic Cancer 1 item
  29. Hepatitis C 2item
  30. Hepatocellular Carcinoma 2item
  31. HIV 4item
  32. HIV Infections 4item
  33. Hypercholesterolemia 1 item
  34. Inflammatory Diseases 9item
  35. Leukemia 8item
  36. Liver Cancer 1 item
  37. Lung Cancer 14item
  38. Lung Carcinoma 2item
  39. Lymphoma 15item
  40. Medulloblastoma 1 item
  41. Melanoma 15item
  42. Mixed Lineage Leukemia 1 item
  43. Multiple Myeloma 7item
  44. Myelofibrosis 1 item
  45. Myeloma 3item
  46. Neuroblastoma 2item
  47. Non-small Cell Lung Cancer 10item
  48. Non-small Cell Lung Carcinoma 1 item
  49. Osteoporosis 1 item
  50. Ovarian Cancer 14item
  51. Pancreatic Cancer 19item
  52. Pancreatic Carcinoma 1 item
  53. Prostate Cancer 25item
  54. Psoriasis 1 item
  55. Pulmonary Arterial Hypertension 1 item
  56. Renal Cancer 3item
  57. Renal Cell Carcinoma 4item
  58. Rheumatoid Arthritis 6item
  59. Schizophrenia 1 item
  60. Sleep Disorders 1 item
  61. Squamous Cell Carcinoma 1 item
  62. Testicular Cancer 1 item
  63. Thyroid Cancer 4item
  64. Tuberculosis 1 item
  65. Type 2 Diabetes 8item