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  • Search results for: 'mutant idh1 inhibitor'

Search results for: 'mutant idh1 inhibitor'

Items 81-90 of 218

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  1. LDC000067
    B4754 LDC000067
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK9 inhibitor, novel and highly specific
      insoluble in H2O; insoluble in EtOH; ≥18.52 mg/mL
  2. BMS265246
    A8385 BMS265246
    Target: Cyclin-Dependent Kinases
    Summary: CDK1/2 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥17.25 mg/mL
  3. CVT-313
    A3336 CVT-313
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Cdk2 inhibitor
      ≥20 mg/mL
  4. THZ531
    A8736 THZ531
    Target: Cyclin-Dependent Kinases
    Summary: CDK12 and CDK13 covalent inhibitor
      ≥55.8 mg/mL
  5. CYT997 (Lexibulin)
    B1635 CYT997 (Lexibulin)
    Summary: Potent microtubule polymerization inhibitor
      Soluble in DMSO
  6. TAI-1
    B4892 TAI-1
    Target: Hec1
    Summary: Hec1 inhibitor, potent, first-in-class
      ≥43.2 mg/mL
  7. XL413 hydrochloride
    B1015 XL413 hydrochloride
    Summary: Cdc7 inhibitor
      ≥32.6 mg/mL
  8. LEE011 hydrochloride
    B1083 LEE011 hydrochloride
    Summary: CDK inhibitor
      Soluble in DMSO
  9. LEE011 succinate
    B1084 LEE011 succinate
    Summary: CDK inhibitor
      Soluble in DMSO
  10. MK-8776 (SCH-900776)
    A8477 MK-8776 (SCH-900776)
    Target: Chk
    Summary: Chk1 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥18.8 mg/mL

Items 81-90 of 218

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  1. ATM/ATR 9item
  2. Aurora Kinase 28item
  3. Cdc42 4item
  4. Cdc7 2item
  5. Chk 15item
  6. c-Myc 3item
  7. CRM1 4item
  8. Cyclin-Dependent Kinases 63item
  9. E1 enzyme 1 item
  10. G-quadruplex 2item
  11. Haspin 1 item
  12. HMTase 1 item
  13. Kinesin 7item
  14. Ksp 4item
  15. Microtubule/Tubulin 14item
  16. Mps1 3item
  17. Mitotic 1 item
  18. RAD51 2item
  19. ROCK 15item
  20. Rho 11item
  21. PAK1 4item
  22. PAK4 2item
  23. PERK 4item
  24. PLK 17item
  25. PTEN 2item
  26. Wee1 1 item
Specificity
  1. Selective 74item
Reversibility
  1. Reversible 9item
  2. Irreversible 2item
Target
  1. Cyclin-Dependent Kinases 30item
  2. PI3K 2item
  3. Aurora Kinases 20item
  4. mTOR 1 item
  5. FLT3 5item
  6. GSK-3 1 item
  7. PLK 11item
  8. Chk 8item
  9. VEGFR 1 item
  10. PDGFR 1 item
  11. RET 1 item
  12. Bromodomain-containing proteins(BRDs) 1 item
  13. MEK 1 item
  14. FGFR 1 item
  15. Src 3item
  16. Microtubules/Tubulins 2item
  17. ROCK 10item
  18. PAK 3item
  19. JAK 1 item
  20. DNA-PK 1 item
  21. Ksp 2item
  22. PKC 1 item
  23. RAD51 2item
  24. LRRK2 1 item
  25. KRAS G12C 1 item
  26. PKG 1 item
  27. PKA 1 item
  28. Myosin light chain kinases (MLCKs) 1 item
  29. Clk 1 item
  30. MK2 1 item
  31. ATM/ATR 6item
  32. Cdc42 1 item
  33. Hck 1 item
  34. Arp2/3 complex 1 item
  35. Cdc7 1 item
  36. Ubiquitin-activating Enzyme E1 1 item
  37. Microtubule/Tubulin 1 item
  38. VEGFR3/FLT4 1 item
  39. NTRK1/TRKA 1 item
  40. CSF-1R/c-Fms 1 item
  41. nuclear export 1 item
  42. CRM1 1 item
  43. Hec1 1 item
  44. Histone Acetyltransferases (HATs) 1 item
  45. Rho 1 item
  46. Lck 1 item
  47. FGR 1 item
  48. YES 1 item
  49. Fyn 1 item
  50. ARG 1 item
  51. Rho-kinase 1 item
  52. ATM 1 item
  53. PTEN 1 item
Reported Experiments
  1. Animal Experiments 83item
  2. Cell Experiments 68item
Related Disease
  1. Acute Myeloid Leukemia 7item
  2. B-lymphoid Malignancies 1 item
  3. Breast Cancer 14item
  4. Cancer 70item
  5. Cervical Cancer 1 item
  6. Chronic Lymphocytic Leukemia 2item
  7. Colon Cancer 10item
  8. Colon Carcinoma 1 item
  9. Colorectal Cancer 5item
  10. Glioblastoma 2item
  11. Glioma 2item
  12. Leukemia 1 item
  13. Liver Cancer 1 item
  14. Lung Cancer 6item
  15. Lymphoma 3item
  16. Mantle Cell Lymphoma 1 item
  17. Melanoma 2item
  18. Multiple Myeloma 1 item
  19. Neuroblastoma 1 item
  20. Non-small Cell Lung Carcinoma 1 item
  21. Ovarian Cancer 7item
  22. Pancreatic Cancer 6item
  23. Prostate Cancer 5item
  24. Renal Cell Carcinoma 1 item
  25. Thyroid Cancer 1 item