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  • Search results for: 'mutant idh1 inhibitor'

Search results for: 'mutant idh1 inhibitor'

Items 11-20 of 139

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  1. NSC 319726
    A4208 NSC 319726
    Target: p53
    Summary: Reactivator of mutant p53
  2. PRIMA-1MET
    A4484 PRIMA-1MET
    Summary: Restore mutant p53 activity, induce BAX and PUMA
  3. Boc-D-FMK
    A1904 Boc-D-FMK
     1 Citation
    Target: Caspases
    Summary: Pan-caspase inhibitor
      insoluble in H2O; ≥11.65 mg/mL
  4. TASIN-1
    A8738 TASIN-1
    Summary: inhibitor of mutant adenomatous polyposis coli (APC)
      ≥35.2 mg/mL
  5. Z-DEVD-FMK
    A1920 Z-DEVD-FMK
     12 Citation
    Target: Caspases
    Summary: Caspase-3 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥60 mg/mL
  6. Ac-DEVD-CMK
    C5528 Ac-DEVD-CMK
    Summary: cell-permeable, and irreversible inhibitor of caspase
      ≤50 mg/mL
  7. Z-VDVAD-FMK
    A1922 Z-VDVAD-FMK
    Summary: Caspase-2 inhibitor
      ≥34.8 mg/mL
  8. Z-VEID-FMK
    A1923 Z-VEID-FMK
     2 Citation
    Target: Caspases
    Summary: Caspase-6 inhibitor
      insoluble in H2O; ≥113.4 mg/mL
  9. Z-FA-FMK
    A8170 Z-FA-FMK
    Target: cysteine protease
    Summary: Cysteine proteases inhibitor
      insoluble in H2O; ≥13.45 mg/mL
  10. PRIMA-1
    A4483 PRIMA-1
    Target: p53
    Summary: BAX inhibitor
      ≥110.6 mg/mL

Items 11-20 of 139

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Category
  1. Caspase 23item
  2. Apoptosis Inducers 13item
  3. Bax 5item
  4. Bcl-2 Family 25item
  5. Bcl-xL 7item
  6. c-RET 8item
  7. IAP 7item
  8. KEAP1-Nrf2 1 item
  9. MDM2 9item
  10. p53 22item
  11. PC-PLC 4item
  12. PKD 5item
  13. RasGAP (Ras- P21) 1 item
  14. Survivin 2item
  15. Thymidylate Synthase 2item
  16. TNF-α 11item
  17. Other Apoptosis 3item
  18. APC 1 item
  19. PD-1/PD-L1 interaction 3item
  20. ASK1 3item
Specificity
  1. Selective 41item
Reversibility
  1. Reversible 1 item
  2. Irreversible 9item
Target
  1. Caspases 13item
  2. Proteasome 1 item
  3. Histone Deacetylases (HDACs) 2item
  4. Inhibitor of apoptosis proteins (IAP) 2item
  5. Bcl-2 8item
  6. Raf 2item
  7. Aurora Kinases 1 item
  8. Bcl-xl 3item
  9. MDM2 1 item
  10. VEGFR 3item
  11. PDGFR 3item
  12. c-Kit 2item
  13. RET 1 item
  14. Mcl-1 7item
  15. Thymidylate Synthase 1 item
  16. Bcr-Abl 1 item
  17. Nrf2 1 item
  18. Sir2-like Family Deacetylases (Sirtuins) 1 item
  19. Deubiquitinating enzymes (DUBs) 1 item
  20. RIP kinases 1 item
  21. PD-1/PD-L1 interaction 1 item
  22. Survivin 1 item
  23. Dehydrogenase 1 item
  24. Autophagy 1 item
  25. Mixed lineage kinase domain-like protein (MLKL) 1 item
  26. angiogenesis 1 item
  27. c-RET 1 item
  28. Bfl-1 1 item
  29. p53-MDM2 interaction 2item
  30. p53 5item
  31. cysteine protease 1 item
  32. PC-PLC 2item
  33. AAT 1 item
  34. Histone Acetyltransferases (HATs) 1 item
  35. Tyrosinases 1 item
  36. HSP70 1 item
  37. Ubiquitin E3 Ligases 1 item
  38. MDMX 1 item
  39. p21 1 item
  40. DHFR 1 item
  41. GARFT 1 item
  42. PKD 1 item
  43. MCL1 1 item
  44. Bcl-w 1 item
  45. Bax 1 item
  46. NS3/4a Proteases 1 item
Reported Experiments
  1. Animal Experiments 53item
  2. Cell Experiments 45item
Related Disease
  1. Acute Myeloid Leukemia 1 item
  2. Adrenocortical Carcinoma 1 item
  3. Autoimmune Diseases 1 item
  4. Breast Cancer 5item
  5. Cancer 35item
  6. Chronic Lymphocytic Leukemia 1 item
  7. Chronic Myeloproliferative Disorders 1 item
  8. Colon Cancer 2item
  9. Colorectal Cancer 2item
  10. Glioblastoma 4item
  11. HCV 1 item
  12. Hepatocellular Carcinoma 1 item
  13. Inflammatory Diseases 1 item
  14. Lung Cancer 1 item
  15. Lymphoma 2item
  16. Melanoma 1 item
  17. Multiple Myeloma 2item
  18. Myelofibrosis 1 item
  19. Neuroblastoma 1 item
  20. Non-small Cell Lung Cancer 3item
  21. Ovarian Cancer 1 item
  22. Pancreatic Cancer 3item
  23. Prostate Cancer 5item
  24. Pulmonary Fibrosis 1 item
  25. Rheumatoid Arthritis 1 item
  26. Soft Tissue Sarcoma 1 item
  27. Testicular Cancer 1 item