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  • Search results for: 'mutant idh1 inhibitor'

Search results for: 'mutant idh1 inhibitor'

Items 11-20 of 53

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  1. S63845
    A8737 S63845
     11 Citation
    Target: MCL1
    Summary: MCL1 inhibitor
  2. Marinopyrrole A
    B1080 Marinopyrrole A
    Target: Mcl-1
    Summary: Selective Mcl-1 inhibitor
      Soluble in DMSO
  3. D609
    A3343 D609
    Target: PC-PLC
    Summary: PC-PLC inhibitor
      ≥12.7 mg/mL
  4. Z-IETD-FMK
    B3232 Z-IETD-FMK
     12 Citation
    Target: Caspases
    Summary: Caspase-8 inhibitor
      ≥32.73 mg/mL
  5. Apogossypolone (ApoG2)
    A4200 Apogossypolone (ApoG2)
     2 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor,nonpeptidic small molecule
      ≥24.55 mg/mL
  6. RG7112
    A3762 RG7112
     5 Citation
    Target: MDM2
    Summary: MDM2 inhibitor, first clinical
      ≥36.4 mg/mL
  7. YM155
    A4221 YM155
     2 Citation
    Target: Survivin
    Summary: Survivin suppressant,apoptosis inhibitor
      ≥22.15 mg/mL
  8. Sabutoclax
    A4199 Sabutoclax
     2 Citation
    Target: Bcl-2|Mcl-1|Bfl-1
    Summary: pan-Bcl-2 inhibitor
      insoluble in H2O; ≥205.6 mg/mL
  9. Z-YVAD-FMK
    A8955 Z-YVAD-FMK
     7 Citation
    Target: Caspases
    Summary: Caspase-1 inhibitor
      ≥31.55 mg/mL
  10. Pifithrin-μ
    A4482 Pifithrin-μ
     1 Citation
    Target: Autophagy|p53|HSP70
    Summary: Inhibitor of p53 binding and anti-apoptotic
      insoluble in H2O; ≥18.1 mg/mL

Items 11-20 of 53

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Category
  1. Caspase 9item
  2. Apoptosis Inducers 6item
  3. Bax 2item
  4. Bcl-2 Family 16item
  5. Bcl-xL 2item
  6. c-RET 4item
  7. IAP 3item
  8. KEAP1-Nrf2 1 item
  9. MDM2 1 item
  10. p53 7item
  11. PC-PLC 2item
  12. PKD 1 item
  13. Survivin 1 item
  14. Thymidylate Synthase 1 item
  15. TNF-α 5item
Specificity
  1. Selective 33item
Reversibility
  1. Irreversible 7item
Target
  1. Caspases 8item
  2. Proteasome 1 item
  3. Histone Deacetylases (HDACs) 2item
  4. Inhibitor of apoptosis proteins (IAP) 2item
  5. Bcl-2 8item
  6. Raf 2item
  7. Aurora Kinases 1 item
  8. Bcl-xl 2item
  9. MDM2 1 item
  10. VEGFR 3item
  11. PDGFR 3item
  12. c-Kit 2item
  13. RET 1 item
  14. Mcl-1 6item
  15. Thymidylate Synthase 1 item
  16. Bcr-Abl 1 item
  17. Nrf2 1 item
  18. Sir2-like Family Deacetylases (Sirtuins) 1 item
  19. Deubiquitinating enzymes (DUBs) 1 item
  20. RIP kinases 1 item
  21. Survivin 1 item
  22. Dehydrogenase 1 item
  23. Autophagy 1 item
  24. angiogenesis 1 item
  25. c-RET 1 item
  26. Bfl-1 1 item
  27. p53-MDM2 interaction 1 item
  28. p53 5item
  29. cysteine protease 1 item
  30. PC-PLC 2item
  31. Histone Acetyltransferases (HATs) 1 item
  32. Tyrosinases 1 item
  33. HSP70 1 item
  34. Ubiquitin E3 Ligases 1 item
  35. p21 1 item
  36. DHFR 1 item
  37. GARFT 1 item
  38. PKD 1 item
  39. MCL1 1 item
  40. Bcl-w 1 item
  41. Bax 1 item
  42. NS3/4a Proteases 1 item
Related Disease
  1. Acute Myeloid Leukemia 1 item
  2. Adrenocortical Carcinoma 1 item
  3. Autoimmune Diseases 1 item
  4. Breast Cancer 5item
  5. Cancer 34item
  6. Chronic Lymphocytic Leukemia 1 item
  7. Chronic Myeloproliferative Disorders 1 item
  8. Colon Cancer 1 item
  9. Colorectal Cancer 2item
  10. Glioblastoma 4item
  11. HCV 1 item
  12. Hepatocellular Carcinoma 1 item
  13. Inflammatory Diseases 1 item
  14. Lung Cancer 1 item
  15. Lymphoma 2item
  16. Melanoma 1 item
  17. Multiple Myeloma 2item
  18. Myelofibrosis 1 item
  19. Neuroblastoma 1 item
  20. Non-small Cell Lung Cancer 3item
  21. Ovarian Cancer 1 item
  22. Pancreatic Cancer 3item
  23. Prostate Cancer 5item
  24. Pulmonary Fibrosis 1 item
  25. Rheumatoid Arthritis 1 item
  26. Soft Tissue Sarcoma 1 item
  27. Testicular Cancer 1 item