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  • Search results for: 'mutant idh1 inhibitor'

Search results for: 'mutant idh1 inhibitor'

Items 21-30 of 53

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  1. Pifithrin-α (PFTα)
    A4206 Pifithrin-α (PFTα)
     2 Citation
    Target: p53
    Summary: p53 inhibitor
      insoluble in H2O; ≥17.45 mg/mL
  2. Z-LEHD-FMK
    B3233 Z-LEHD-FMK
     8 Citation
    Target: Caspases
    Summary: Irreversible Caspase-9 inhibitor.
      insoluble in H2O; ≥107.4 mg/mL
  3. CID 755673
    A8678 CID 755673
    Target: PKD
    Summary: PKD inhibitor
  4. LCL161
    A3541 LCL161
     1 Citation
    Target: Inhibitor of apoptosis proteins (IAP)
    Summary: Antagonist of IAPs inhibitor
      ≥25.05 mg/mL
  5. NSC 687852 (b-AP15)
    A4453 NSC 687852 (b-AP15)
    Target: Deubiquitinating enzymes (DUBs)
    Summary: 19S regulatory particle Inhibitor
      insoluble in EtOH; insoluble in H2O; ≥20.95 mg/mL
  6. VX-765
    A8238 VX-765
     1 Citation
    Target: Caspases
    Summary: Caspase-1 inhibitor,potent and selective
      insoluble in H2O; ≥313 mg/mL
  7. Radotinib(IY-5511)
    B5846 Radotinib(IY-5511)
    Target: PDGFR|Bcr-Abl
    Summary: Bcr-Abl tyrosine kinase inhibitor
      ≥13.73 mg/mL
  8. ABT-199
    A8194 ABT-199
     14 Citation
    Target: Bcl-2
    Summary: Bcl-2 inhibitor,potent and selective
      ≥43.42 mg/mL
  9. Danusertib (PHA-739358)
    A4116 Danusertib (PHA-739358)
     2 Citation
    Target: Aurora Kinases
    Summary: Pan-aurora kinase inhibitor
      ≥23.75 mg/mL
  10. U-73122
    B3422 U-73122
     1 Citation
    Target: PC-PLC
    Summary: inhibitor of phospholipase C, phospholipase A2, and 5-LO (5-lipoxygenase)

Items 21-30 of 53

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Category
  1. Caspase 9item
  2. Apoptosis Inducers 6item
  3. Bax 2item
  4. Bcl-2 Family 16item
  5. Bcl-xL 2item
  6. c-RET 4item
  7. IAP 3item
  8. KEAP1-Nrf2 1 item
  9. MDM2 1 item
  10. p53 7item
  11. PC-PLC 2item
  12. PKD 1 item
  13. Survivin 1 item
  14. Thymidylate Synthase 1 item
  15. TNF-α 5item
Specificity
  1. Selective 33item
Reversibility
  1. Irreversible 7item
Target
  1. Caspases 8item
  2. Proteasome 1 item
  3. Histone Deacetylases (HDACs) 2item
  4. Inhibitor of apoptosis proteins (IAP) 2item
  5. Bcl-2 8item
  6. Raf 2item
  7. Aurora Kinases 1 item
  8. Bcl-xl 2item
  9. MDM2 1 item
  10. VEGFR 3item
  11. PDGFR 3item
  12. c-Kit 2item
  13. RET 1 item
  14. Mcl-1 6item
  15. Thymidylate Synthase 1 item
  16. Bcr-Abl 1 item
  17. Nrf2 1 item
  18. Sir2-like Family Deacetylases (Sirtuins) 1 item
  19. Deubiquitinating enzymes (DUBs) 1 item
  20. RIP kinases 1 item
  21. Survivin 1 item
  22. Dehydrogenase 1 item
  23. Autophagy 1 item
  24. angiogenesis 1 item
  25. c-RET 1 item
  26. Bfl-1 1 item
  27. p53-MDM2 interaction 1 item
  28. p53 5item
  29. cysteine protease 1 item
  30. PC-PLC 2item
  31. Histone Acetyltransferases (HATs) 1 item
  32. Tyrosinases 1 item
  33. HSP70 1 item
  34. Ubiquitin E3 Ligases 1 item
  35. p21 1 item
  36. DHFR 1 item
  37. GARFT 1 item
  38. PKD 1 item
  39. MCL1 1 item
  40. Bcl-w 1 item
  41. Bax 1 item
  42. NS3/4a Proteases 1 item
Related Disease
  1. Acute Myeloid Leukemia 1 item
  2. Adrenocortical Carcinoma 1 item
  3. Autoimmune Diseases 1 item
  4. Breast Cancer 5item
  5. Cancer 34item
  6. Chronic Lymphocytic Leukemia 1 item
  7. Chronic Myeloproliferative Disorders 1 item
  8. Colon Cancer 1 item
  9. Colorectal Cancer 2item
  10. Glioblastoma 4item
  11. HCV 1 item
  12. Hepatocellular Carcinoma 1 item
  13. Inflammatory Diseases 1 item
  14. Lung Cancer 1 item
  15. Lymphoma 2item
  16. Melanoma 1 item
  17. Multiple Myeloma 2item
  18. Myelofibrosis 1 item
  19. Neuroblastoma 1 item
  20. Non-small Cell Lung Cancer 3item
  21. Ovarian Cancer 1 item
  22. Pancreatic Cancer 3item
  23. Prostate Cancer 5item
  24. Pulmonary Fibrosis 1 item
  25. Rheumatoid Arthritis 1 item
  26. Soft Tissue Sarcoma 1 item
  27. Testicular Cancer 1 item