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  • Search results for: 'mutant idh1 inhibitor'

Search results for: 'mutant idh1 inhibitor'

Items 11-20 of 96

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  1. EX 527 (SEN0014196)
    A4181 EX 527 (SEN0014196)
     1 Citation
    Target: Sirtuin
    Summary: SIRT1 inhibitor
      insoluble in H2O; ≥12.43 mg/mL
  2. LY2784544
    A4147 LY2784544
    Target: Aurora Kinases|FLT3|VEGFR|FGFR|Trk Receptors|JAK|ALK|TYK2|MUSK|MAP3K
    Summary: JAK2 inhibitor,highly potent and selective
      ≥23.5 mg/mL
  3. VX-680 (MK-0457,Tozasertib)
    A4111 VX-680 (MK-0457,Tozasertib)
    Target: Aurora Kinases
    Summary: Aurora kinase inhibitor
      ≥23.25 mg/mL
  4. WHI-P154
    A4150 WHI-P154
    Target: VEGFR|Src|EGFR|JAK
    Summary: JAK3 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥125.6 mg/mL
  5. MLN8054
    A4114 MLN8054
    Target: Aurora Kinases
    Summary: Aurora A inhibitor
      insoluble in EtOH; insoluble in H2O; ≥39.05 mg/mL
  6. 3-Deazaneplanocin A (DZNep) hydrochloride
    A8182 3-Deazaneplanocin A (DZNep) hydrochloride
     1 Citation
    Target: EZH2
    Summary: SAHH and EZH2 inhibitor
      insoluble in EtOH; ≥14.94 mg/mL
  7. PJ34
    A3729 PJ34
    Target: PARP
    Summary: PARP-l inhibitor
      ≥50.9 mg/mL
  8. Lomeguatrib
    A1912 Lomeguatrib
    Target: O6-methylguanine-DNA-methyl-transferase (MGMT)
    Summary: MGMT inhibitor
      ≥50 mg/mL
  9. RG2833
    A3761 RG2833
    Target: HDAC
    Summary: Brain-penetrant HDAC inhibitor
      insoluble in H2O; ≥16.95 mg/mL
  10. Valproic acid
    B1251 Valproic acid
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC1 inhibitor
      ≥12.35 mg/mL

Items 11-20 of 96

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  1. Category Chromatin/Epigenetics Remove This Item
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Category
  1. Bromodomain 7item
  2. Aurora Kinase 17item
  3. DNA Methyltransferase 2item
  4. HDAC 28item
  5. Histone Acetyltransferases 2item
  6. Histone Demethylases 2item
  7. Histone Methyltransferase 8item
  8. HIF 3item
  9. JAK 14item
  10. PARP 6item
  11. Pim 2item
  12. Protein Ser/Thr Phosphatases 2item
  13. Sirtuin 2item
  14. Sphingosine Kinase-2 1 item
Specificity
  1. Selective 61item
Reversibility
  1. Reversible 4item
  2. Irreversible 2item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 24item
  3. Aurora Kinases 17item
  4. EZH2 1 item
  5. Bromodomains 5item
  6. FLT3 5item
  7. PLK 1 item
  8. VEGFR 3item
  9. RET 1 item
  10. Hydrolase 1 item
  11. MEK 1 item
  12. DOT1L 1 item
  13. FGFR 2item
  14. Pim 2item
  15. Sir2-like Family Deacetylases (Sirtuins) 1 item
  16. Src 4item
  17. Trk Receptors 1 item
  18. STAT 2item
  19. EGFR 2item
  20. Hypoxia Inducible Factors (HIFs) 1 item
  21. JAK 15item
  22. Syk 1 item
  23. ErbB 1 item
  24. DNA Methyltransferases 1 item
  25. LRRK2 1 item
  26. PARP 6item
  27. ALK 1 item
  28. phosphatases 1 item
  29. G9a 1 item
  30. Hck 1 item
  31. MNK 1 item
  32. AChE 1 item
  33. Catechol O-Methyltransferase (COMT) 1 item
  34. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  35. Protein Arginine Methyltransferases 1 item
  36. Cytidine deaminases 1 item
  37. c-RET 1 item
  38. VEGFR3/FLT4 1 item
  39. NTRK1/TRKA 1 item
  40. CSF-1R/c-Fms 1 item
  41. PTP 1 item
  42. Protein polybromo-1 1 item
  43. SMARCA4 1 item
  44. SMARCA2 1 item
  45. p53 1 item
  46. HDAC 2item
  47. KDM 2item
  48. Histone Acetyltransferases (HATs) 2item
  49. Trx 1 item
  50. HIF-PH 1 item
  51. L3MBTL 1 item
  52. TYK2 2item
  53. MUSK 1 item
  54. MAP3K 1 item
  55. Lck 1 item
  56. p21 1 item
  57. PHF 1 item
  58. FGR 1 item
  59. YES 1 item
  60. Fyn 1 item
  61. ARG 1 item
  62. LSD 1 item
  63. PRMT 1 item
  64. GLP 1 item
  65. SK 1 item
  66. Sirtuin 1 item
Related Disease
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  2. Acute Myeloid Leukemia 6item
  3. Bladder Cancer 2item
  4. Bladder Carcinoma 1 item
  5. Breast Cancer 11item
  6. Cancer 51item
  7. Castration-resistant Prostate Cancer 1 item
  8. Cervical Cancer 1 item
  9. Chronic Lymphocytic Leukemia 1 item
  10. Colon Cancer 4item
  11. Colorectal Cancer 3item
  12. Diffuse Large B-cell Lymphoma 1 item
  13. Dyskinesia 1 item
  14. Epilepsy 1 item
  15. Friedreich's Ataxia 1 item
  16. Glioblastoma 2item
  17. Glioma 1 item
  18. HIV 1 item
  19. HIV Infections 2item
  20. Inflammatory Diseases 1 item
  21. Leukemia 3item
  22. Lung Cancer 3item
  23. Lymphoma 4item
  24. Melanoma 2item
  25. Mixed Lineage Leukemia 1 item
  26. Multiple Myeloma 3item
  27. Myelofibrosis 1 item
  28. Neuroblastoma 2item
  29. Neuronal Protection 1 item
  30. Non-small Cell Lung Cancer 3item
  31. Ovarian Cancer 3item
  32. Pancreatic Cancer 3item
  33. Prostate Cancer 7item
  34. Psoriasis 1 item
  35. Renal Cancer 1 item
  36. Renal Cell Carcinoma 1 item
  37. Rheumatoid Arthritis 2item
  38. Thyroid Cancer 1 item