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  • Search results for: 'mutant idh1 inhibitor'

Search results for: 'mutant idh1 inhibitor'

Items 31-40 of 345

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  1. AMI-1
    A1908 AMI-1
    Summary: PRMT1 inhibitor
      insoluble in EtOH; insoluble in DMSO; ≥19.1 mg/mL
  2. M344
    A4105 M344
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,potent and cell-permeable
  3. AGK7
    C5709 AGK7
    Summary: cell-permeable, selective inhibitor of SIRT2
      ≤0.5 mg/mL
  4. EX 527 (SEN0014196)
    A4181 EX 527 (SEN0014196)
     1 Citation
    Target: Sirtuin
    Summary: SIRT1 inhibitor
      insoluble in H2O; ≥12.43 mg/mL
  5. Entinostat (MS-275,SNDX-275)
    A8171 Entinostat (MS-275,SNDX-275)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC1 and HDAC3 inhibitor
      insoluble in H2O; ≥18.8 mg/mL
  6. LY2784544
    A4147 LY2784544
    Target: Aurora Kinases|FLT3|VEGFR|FGFR|Trk Receptors|JAK|ALK|TYK2|MUSK|MAP3K
    Summary: JAK2 inhibitor,highly potent and selective
      ≥23.5 mg/mL
  7. MK-4827 hydrochloride
    B1163 MK-4827 hydrochloride
    Summary: PARP1/PARP2 inhibitor
      Soluble in DMSO
  8. MK-4827 tosylate
    B1164 MK-4827 tosylate
    Summary: PARP1/PARP2 inhibitor
      Soluble in DMSO
  9. VX-680 (MK-0457,Tozasertib)
    A4111 VX-680 (MK-0457,Tozasertib)
    Target: Aurora Kinases
    Summary: Aurora kinase inhibitor
      ≥23.25 mg/mL
  10. CCT007093
    B3274 CCT007093
    Summary: PPM1D inhibitor
      insoluble in EtOH; insoluble in H2O; ≥3.4 mg/mL

Items 31-40 of 345

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  1. Category Chromatin/Epigenetics Remove This Item
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Category
  1. Bromodomain 34item
  2. Aurora Kinase 30item
  3. DNA Methyltransferase 6item
  4. HDAC 55item
  5. Histone Acetyltransferases 15item
  6. Histone Demethylases 22item
  7. Histone Methyltransferase 41item
  8. HIF 11item
  9. JAK 41item
  10. MBT Domains 1 item
  11. PARP 31item
  12. Pim 8item
  13. Protein Ser/Thr Phosphatases 29item
  14. RNA Polymerase 3item
  15. Sirtuin 14item
  16. Sphingosine Kinase-2 1 item
  17. Polycomb repressive complex 1 item
  18. SUMOylation 2item
  19. PAD 1 item
Specificity
  1. Selective 104item
Reversibility
  1. Reversible 7item
  2. Irreversible 2item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 33item
  3. PI3K 1 item
  4. Aurora Kinases 21item
  5. EZH2 3item
  6. Bromodomains 8item
  7. FLT3 5item
  8. PLK 1 item
  9. VEGFR 3item
  10. RET 1 item
  11. Hydrolase 1 item
  12. MEK 1 item
  13. DOT1L 3item
  14. FGFR 2item
  15. Nrf2 1 item
  16. Pim 3item
  17. Sir2-like Family Deacetylases (Sirtuins) 3item
  18. Src 4item
  19. Trk Receptors 1 item
  20. STAT 2item
  21. EGFR 2item
  22. Hypoxia Inducible Factors (HIFs) 2item
  23. Tankyrases 1 item
  24. JAK 20item
  25. p300 1 item
  26. Syk 1 item
  27. EZH1 1 item
  28. TNKS 1 item
  29. ErbB 1 item
  30. DNA Methyltransferases 3item
  31. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  32. SMYD2 1 item
  33. CREBBP 2item
  34. EP300 2item
  35. LRRK2 1 item
  36. PARP 8item
  37. ALK 1 item
  38. Bromodomain and Extra-Terminal motif (BET) 1 item
  39. phosphatases 1 item
  40. NAT10 1 item
  41. G9a 2item
  42. Hck 1 item
  43. SETD7 1 item
  44. MNK 1 item
  45. AChE 1 item
  46. Catechol O-Methyltransferase (COMT) 1 item
  47. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  48. Protein Arginine Methyltransferases 1 item
  49. Cytidine deaminases 1 item
  50. c-RET 1 item
  51. VEGFR3/FLT4 1 item
  52. NTRK1/TRKA 1 item
  53. CSF-1R/c-Fms 1 item
  54. PTP 1 item
  55. Protein polybromo-1 1 item
  56. SMARCA4 1 item
  57. SMARCA2 1 item
  58. p53 1 item
  59. HDAC 2item
  60. KDM 2item
  61. Histone Acetyltransferases (HATs) 2item
  62. Trx 1 item
  63. HIF-PH 1 item
  64. L3MBTL 1 item
  65. TYK2 2item
  66. MUSK 1 item
  67. MAP3K 1 item
  68. Lck 1 item
  69. p21 1 item
  70. PHF 1 item
  71. FGR 1 item
  72. YES 1 item
  73. Fyn 1 item
  74. ARG 1 item
  75. LSD 1 item
  76. PRMT 1 item
  77. GLP 1 item
  78. SK 1 item
  79. Sirtuin 1 item
Reported Experiments
  1. Animal Experiments 116item
  2. Cell Experiments 96item
Related Disease
  1. Acute Myelogenous Leukemia 2item
  2. Acute Myeloid Leukemia 8item
  3. Bladder Cancer 2item
  4. Bladder Carcinoma 1 item
  5. Breast Cancer 19item
  6. Cancer 82item
  7. Castration-resistant Prostate Cancer 1 item
  8. Cervical Cancer 2item
  9. Chronic Lymphocytic Leukemia 1 item
  10. Colon Cancer 11item
  11. Colon Carcinoma 1 item
  12. Colorectal Cancer 5item
  13. Diabetes 1 item
  14. Diffuse Large B-cell Lymphoma 1 item
  15. Dyskinesia 1 item
  16. Epilepsy 1 item
  17. Friedreich's Ataxia 1 item
  18. Glioblastoma 2item
  19. Glioma 2item
  20. Hepatic Cancer 1 item
  21. Hepatocellular Carcinoma 1 item
  22. HIV 2item
  23. HIV Infections 2item
  24. Immunological Diseases 1 item
  25. Inflammatory Bowel Disease 1 item
  26. Inflammatory Diseases 3item
  27. Leukemia 7item
  28. Lung Cancer 6item
  29. Lymphoma 6item
  30. Melanoma 5item
  31. Mixed Lineage Leukemia 3item
  32. Multiple Myeloma 5item
  33. Myelofibrosis 1 item
  34. Myeloma 1 item
  35. Neuroblastoma 2item
  36. Neuronal Protection 1 item
  37. Non-small Cell Lung Cancer 5item
  38. Ovarian Cancer 5item
  39. Pancreatic Cancer 4item
  40. Prostate Cancer 12item
  41. Psoriasis 1 item
  42. Renal Cancer 1 item
  43. Renal Cell Carcinoma 2item
  44. Rheumatoid Arthritis 3item
  45. Thyroid Cancer 1 item