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  • Search results for: 'mutant idh1 inhibitor'

Search results for: 'mutant idh1 inhibitor'

Items 81-90 of 104

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  1. Barasertib (AZD1152-HQPA)
    A4112 Barasertib (AZD1152-HQPA)
     3 Citation
    Target: Aurora Kinases
    Summary: Aurora Kinase B inhibitor, Potent and selective
      ≥25.4 mg/mL
  2. EPZ-6438
    A8221 EPZ-6438
     5 Citation
    Summary: EZH2 inhibitor, potent and selective
      ≥28.64 mg/mL
  3. EPZ004777
    A4170 EPZ004777
    Target: DOT1L
    Summary: DOT1L inhibitor
      ≥27 mg/mL
  4. JNJ-26481585
    A4090 JNJ-26481585
     3 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: Potent HDAC inhibitor
      insoluble in H2O; insoluble in EtOH; ≥19.2 mg/mL
  5. AZD1152
    A3214 AZD1152
     1 Citation
    Target: Aurora Kinases
    Summary: Aurora B kinase inhibitor,highly potent and selective
      insoluble in H2O; insoluble in EtOH; ≥5.88 mg/mL
  6. TG101348 (SAR302503)
    A4136 TG101348 (SAR302503)
     2 Citation
    Target: FLT3|JAK|c-RET
    Summary: JAK-2 inhibitor,potent and selective
      ≥26.23 mg/mL
  7. Mocetinostat (MGCD0103, MG0103)
    A4089 Mocetinostat (MGCD0103, MG0103)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,isotype-selective and potent
      insoluble in EtOH; insoluble in H2O; ≥19.8 mg/mL
  8. Entacapone
    A4168 Entacapone
    Target: Catechol O-Methyltransferase (COMT)
    Summary: COMT inhibitor
  9. JNJ-7706621
    A4115 JNJ-7706621
     1 Citation
    Target: Cyclin-Dependent Kinases|Aurora Kinases
    Summary: Potent CDK/Aurora kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥19.7 mg/mL
  10. Cucurbitacin I
    A4512 Cucurbitacin I
    Target: STAT|JAK
    Summary: STAT3/JAK2 signaling inhibitor
      ≥22.45 mg/mL

Items 81-90 of 104

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Category
  1. Bromodomain 10item
  2. Aurora Kinase 13item
  3. DNA Methyltransferase 4item
  4. HDAC 27item
  5. Histone Acetyltransferases 4item
  6. Histone Demethylases 2item
  7. Histone Methyltransferase 15item
  8. HIF 3item
  9. JAK 12item
  10. PARP 6item
  11. Pim 3item
  12. Protein Ser/Thr Phosphatases 2item
  13. Sirtuin 3item
  14. Sphingosine Kinase-2 1 item
Reversibility
  1. Reversible 7item
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 25item
  3. PI3K 1 item
  4. Aurora Kinases 13item
  5. EZH2 3item
  6. Bromodomains 5item
  7. FLT3 1 item
  8. Hydrolase 1 item
  9. MEK 1 item
  10. DOT1L 3item
  11. Nrf2 1 item
  12. Pim 3item
  13. Sir2-like Family Deacetylases (Sirtuins) 2item
  14. Src 1 item
  15. STAT 1 item
  16. Hypoxia Inducible Factors (HIFs) 2item
  17. Tankyrases 1 item
  18. JAK 11item
  19. p300 1 item
  20. Syk 1 item
  21. EZH1 1 item
  22. TNKS 1 item
  23. DNA Methyltransferases 3item
  24. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  25. SMYD2 1 item
  26. CREBBP 2item
  27. EP300 2item
  28. PARP 4item
  29. Bromodomain and Extra-Terminal motif (BET) 1 item
  30. phosphatases 1 item
  31. NAT10 1 item
  32. G9a 2item
  33. SETD7 1 item
  34. AChE 1 item
  35. Catechol O-Methyltransferase (COMT) 1 item
  36. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  37. Protein Arginine Methyltransferases 1 item
  38. Cytidine deaminases 1 item
  39. c-RET 1 item
  40. Protein polybromo-1 1 item
  41. SMARCA4 1 item
  42. SMARCA2 1 item
  43. HDAC 1 item
  44. Histone Acetyltransferases (HATs) 1 item
  45. TYK2 1 item
  46. Lck 1 item
  47. LSD 1 item
  48. PRMT 1 item
  49. GLP 1 item
  50. SK 1 item
  51. Sirtuin 1 item
Reported Experiments
  1. Animal Experiments 84item
  2. Cell Experiments 61item
Related Disease
  1. Acute Myelogenous Leukemia 2item
  2. Acute Myeloid Leukemia 8item
  3. Bladder Cancer 2item
  4. Bladder Carcinoma 1 item
  5. Breast Cancer 18item
  6. Cancer 63item
  7. Castration-resistant Prostate Cancer 1 item
  8. Cervical Cancer 1 item
  9. Chronic Lymphocytic Leukemia 1 item
  10. Colon Cancer 10item
  11. Colon Carcinoma 1 item
  12. Colorectal Cancer 5item
  13. Diabetes 1 item
  14. Diffuse Large B-cell Lymphoma 1 item
  15. Dyskinesia 1 item
  16. Epilepsy 1 item
  17. Friedreich's Ataxia 1 item
  18. Glioblastoma 2item
  19. Glioma 2item
  20. Hepatic Cancer 1 item
  21. Hepatocellular Carcinoma 1 item
  22. HIV Infections 2item
  23. Immunological Diseases 1 item
  24. Inflammatory Bowel Disease 1 item
  25. Inflammatory Diseases 2item
  26. Leukemia 7item
  27. Lung Cancer 6item
  28. Lymphoma 6item
  29. Melanoma 5item
  30. Mixed Lineage Leukemia 3item
  31. Multiple Myeloma 5item
  32. Myelofibrosis 1 item
  33. Myeloma 1 item
  34. Neuroblastoma 2item
  35. Neuronal Protection 1 item
  36. Non-small Cell Lung Cancer 5item
  37. Ovarian Cancer 5item
  38. Pancreatic Cancer 4item
  39. Prostate Cancer 12item
  40. Psoriasis 1 item
  41. Renal Cancer 1 item
  42. Renal Cell Carcinoma 2item
  43. Rheumatoid Arthritis 3item
  44. Thyroid Cancer 1 item