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Search results for: 'mutant idh1 inhibitor'

Search results for: 'mutant idh1 inhibitor'

A5793 Quizartinib (AC220)

Target: FLT3

Summary: FLT3 inhibitor,potent and selective

≥28.03 mg/mL
B5832 Altiratinib

1 Citation

Target: FLT3|VEGFR|Trk Receptors|c-MET|Tie-2

Summary: c-MET/TIE-2/VEGFR inhibitor

≥21.55 mg/mL
A8394 CHIR-124

Target: FLT3|GSK-3|Chk|PDGFR

Summary: Chk1 inhibitor,novel and potent

insoluble in H2O; ≥10.5 mg/mL
A4125 CYC116

Target: Aurora Kinases|FLT3|VEGFR

Summary: Potent Aurora A/B inhibitor

insoluble in EtOH; insoluble in H2O; ≥18.4 mg/mL
A4136 TG101348 (SAR302503)

2 Citation

Target: FLT3|JAK|c-RET

Summary: JAK-2 inhibitor,potent and selective

≥26.23 mg/mL
B5835 AZD2932

Target: FLT3|VEGFR|PDGFR|c-Kit

Summary: inhibitor of VEGFR-2, PDGFRβ, Flt-3, and c-Kit

Soluble in DMSO
A4130 ENMD-2076

Target: Aurora Kinases|FLT3|RET|Src|VEGFR3/FLT4|NTRK1/TRKA|CSF-1R/c-Fms

Summary: Selective Aurora A/Flt3 inhibitor

insoluble in H2O; ≥18.75 mg/mL
B5854 Pexidartinib (PLX3397)

3 Citation

Target: FLT3|c-Kit|CSF1R

Summary: CSF-1R inhibitor

insoluble in EtOH; insoluble in H2O; ≥20.9 mg/mL
B5953 Dovitinib (TKI258) Lactate

Target: CSF-1R|FLT3|VEGFR|PDGFR|c-Kit|FGFR

Summary: Oral tyrosine kinase inhibitor (TKI) against FGFR1–3, VEGFR1–3, and platelet-derived growth factor receptor (PDGFR).

insoluble in EtOH; ≥10.62 mg/mL