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Search results for: 'mutant idh1 inhibitor'

Items 231-240 of 953

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  1. Tosedostat (CHR2797)
    A4355 Tosedostat (CHR2797)
     1 Citation
    Target: Aminopeptidases
    Summary: Aminopeptidase inhibitor
      ≥40.6 mg/mL
  2. GSK429286A
    A5611 GSK429286A
    Target: ROCK
    Summary: Selective ROCK1/ROCK2 inhibitor
      ≥21.6 mg/mL
  3. THZ1
    A8882 THZ1
     12 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Covalent CDK7 inhibitor,potent and selective
      ≥28.3 mg/mL
  4. Isosafrole
    A8703 Isosafrole
    Target: Lactate Dehydrogenases (LDH)
    Summary: A stiripentol analog, a potent LDH inhibitor.
  5. BMS-509744
    A3250 BMS-509744
    Target: ITK
    Summary: Itk inhibitor,potent and selective
      Soluble in DMSO
  6. Valdecoxib
    B1459 Valdecoxib
    Target: COX
    Summary: COX-2 inhibitor
      insoluble in H2O; ≥15.72 mg/mL
  7. Rofecoxib
    B1454 Rofecoxib
    Target: COX
    Summary: COX-2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥15.72 mg/mL
  8. Golvatinib (E7050)
    B1439 Golvatinib (E7050)
    Target: VEGFR
    Summary: C-Met/VEGFR-2 inhibitor
  9. Z-IETD-FMK
    B3232 Z-IETD-FMK
     12 Citation
    Target: Caspases
    Summary: Caspase-8 inhibitor
      ≥32.73 mg/mL
  10. BMS-911543
    A4152 BMS-911543
    Target: JAK
    Summary: JAK2 inhibitor,selective small molecule
      ≥43.3 mg/mL

Items 231-240 of 953

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  1. Signaling Pathways 917item
  2. Natural Products 6item
  3. Lab Reagents 3item
Specificity
  1. Selective 682item
  2. Non-Selective 5item
Reversibility
  1. Reversible 54item
  2. Irreversible 31item
Target
  1. Caspases 8item
  2. Cyclin-Dependent Kinases 25item
  3. Proteasome 12item
  4. Cathepsins 9item
  5. Histone Deacetylases (HDACs) 32item
  6. Inhibitor of apoptosis proteins (IAP) 2item
  7. Akt 13item
  8. Bcl-2 8item
  9. PI3K 36item
  10. CXCR 3item
  11. Raf 13item
  12. Aurora Kinases 20item
  13. Bcl-xl 2item
  14. CSF-1R 4item
  15. Glycoproteins 1 item
  16. p97 1 item
  17. Gap Junctions 1 item
  18. MDM2 1 item
  19. EZH2 4item
  20. mTOR 20item
  21. Bromodomains 6item
  22. AP-1 1 item
  23. MMP 7item
  24. Thymidine Phosphorylases 1 item
  25. Androgen Receptors 4item
  26. Peptidylprolyl isomerases 1 item
  27. Acyl coenzyme A: cholesterol acyltransferases 1 item
  28. Myosin II ATPases 1 item
  29. DT-diaphorases 1 item
  30. Voltage-gated Potassium (KV) Channels 1 item
  31. MER 1 item
  32. FLT3 19item
  33. GSK-3 10item
  34. Factor Xa 4item
  35. P-glycoprotein (P-gp) 5item
  36. PLK 10item
  37. Chk 7item
  38. Eph Receptors 2item
  39. VEGFR 40item
  40. PDGFR 25item
  41. c-Kit 13item
  42. RET 4item
  43. IRAK 1 item
  44. Bromodomain-containing proteins(BRDs) 1 item
  45. Phosphodiesterases (PDEs) 16item
  46. Mcl-1 6item
  47. Hydrolase 1 item
  48. Thymidylate Synthase 3item
  49. p38 9item
  50. PKB 1 item
  51. JNK 3item
  52. SGK 1 item
  53. Bcr-Abl 13item
  54. Kynurenine-3-monooxygenase 1 item
  55. MEK 13item
  56. PORCN 1 item
  57. DOT1L 3item
  58. FGFR 17item
  59. Nrf2 2item
  60. Insulin-like growth factor receptors(IGFRs) 1 item
  61. Pim 4item
  62. Sir2-like Family Deacetylases (Sirtuins) 3item
  63. Voltage-gated Sodium (NaV) Channels 1 item
  64. Deubiquitinating enzymes (DUBs) 3item
  65. Smoothened 4item
  66. Neuraminidases (NA) 3item
  67. MET 7item
  68. Src 14item
  69. Trk Receptors 6item
  70. Integrins 1 item
  71. Aminopeptidases 3item
  72. NMDA Receptors 1 item
  73. STAT 10item
  74. ATP Citrate Lyases 1 item
  75. Microtubules/Tubulins 4item
  76. EGFR 23item
  77. Hedgehog 1 item
  78. Reverse Transcriptases 6item
  79. ROCK 9item
  80. BTK 1 item
  81. RIP kinases 1 item
  82. Monocyte chemotactic proteins 1 item
  83. PAK 3item
  84. Hypoxia Inducible Factors (HIFs) 2item
  85. Tankyrases 1 item
  86. Inositol Phosphatases 1 item
  87. FAK 7item
  88. BMP and Other Activin Receptors 3item
  89. JAK 20item
  90. p300 1 item
  91. Stearoyl-CoA 9-desaturase (SCD-1) 2item
  92. Syk 7item
  93. EZH1 2item
  94. DNA-PK 7item
  95. HSP90 12item
  96. AMPK 2item
  97. Gutathione S-transferase 1 item
  98. PDHK 1 item
  99. Angiotensin AT2 Receptors 1 item
  100. Notch 1 item
  101. S-nitrosoglutathione reductase 1 item
  102. CFTR 3item
  103. TNKS 1 item
  104. Topoisomerases 12item
  105. Cytochrome P450 (CYP450) 8item
  106. thrombin 1 item
  107. Ksp 2item
  108. Renin 1 item
  109. Influenza viruses 1 item
  110. ErbB 5item
  111. S6 kinases 1 item
  112. Toll-like receptors (TLRs) 3item
  113. Adenosine Kinases 2item
  114. Serine Proteases 2item
  115. DNA Methyltransferases 2item
  116. Survivin 1 item
  117. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  118. ERK 8item
  119. HMG-CoA Reductases 6item
  120. c-MET 8item
  121. BMI-1 1 item
  122. PKC 13item
  123. Calpains 5item
  124. Ubiquitin-specific proteases 1 item
  125. HCV Proteases 3item
  126. Ca2 /calmodulin-dependent protein kinases (CaMKs) 6item
  127. MLK3 1 item
  128. O-GlcNAcase 1 item
  129. CREBBP 1 item
  130. EP300 1 item
  131. Lyn 2item
  132. SGLT 1 item
  133. RAD51 2item
  134. Trypsins 1 item
  135. HER2 3item
  136. Pyk2 3item
  137. USP 1 item
  138. 5-HT2 Receptors 4item
  139. LRRK2 6item
  140. Voltage-gated Calcium Channels (CaV) 2item
  141. DGAT 2item
  142. Insulin and Insulin-like Receptors 4item
  143. PARP 7item
  144. CB1 Receptors 1 item
  145. Pyruvate dehydrogenases (PDH) 2item
  146. ALK 10item
  147. ROS1 2item
  148. Sphingosine kinases (SphKs) 3item
  149. Trypsin 1 item
  150. Chymotrypsin 1 item
  151. Kallikrein 1 item
  152. Trypsinogen 1 item
  153. Monocarboxylate transporters (MCTs) 2item
  154. CETP 2item
  155. Dehydrogenase 1 item
  156. PKG 2item
  157. PKA 6item
  158. Myosin light chain kinases (MLCKs) 2item
  159. HIV-1 gp120 1 item
  160. D1 and D5 Receptors 1 item
  161. D2 Receptors 3item
  162. D3 Receptors 2item
  163. 5-HT1 Receptors 2item
  164. 5-HT7 Receptors 1 item
  165. MELK 1 item
  166. Serotonin reuptake 1 item
  167. Insulin-like growth factors (IGFs) 1 item
  168. CSF1R 1 item
  169. Bromodomain and Extra-Terminal motif (BET) 1 item
  170. Lactate Dehydrogenases (LDH) 2item
  171. MK2 2item
  172. Fatty-acid-binding proteins (FABPs) 1 item
  173. Angiotensin-Converting Enzymes (ACEs) 6item
  174. Tie-2 5item
  175. RSK 3item
  176. p70 S6K 1 item
  177. phosphatases 2item
  178. Autophagy 4item
  179. ATM/ATR 5item
  180. COX 12item
  181. CK1 1 item
  182. CK2 2item
  183. HIPK2 1 item
  184. HIPK3 1 item
  185. HIV Integrases 2item
  186. Squalene epoxidases 2item
  187. PRAK 1 item
  188. MAPKAP-K2 1 item
  189. Delayed rectifier outward potassium current (IKr) 1 item
  190. GpIIb/IIIa receptor 1 item
  191. Guanine nucleotide exchange factors (GEFs) 1 item
  192. 20S proteasomal chymotrypsin 1 item
  193. Geranylgeranyltransferase I 1 item
  194. Farnesyltransferase 1 item
  195. Nampt 3item
  196. eIF4F 1 item
  197. Cdc42 1 item
  198. SRPK1 1 item
  199. P2X Receptors 1 item
  200. Glutaminases 2item
  201. Carbonic Anhydrases 7item
  202. Ron 1 item
  203. G9a 1 item
  204. BLM 1 item
  205. HSV 1 item
  206. NADPH Oxidases 3item
  207. Calcium-activated chloride channels (CaCC) 1 item
  208. GPR35 1 item
  209. Aldehyde Dehydrogenases 1 item
  210. Synthases/Synthetases 2item
  211. MAGL 1 item
  212. Histamine H1 Receptors 2item
  213. Na /K ATPases 3item
  214. P110 1 item
  215. Hck 2item
  216. Inositol-requiring enzyme 1 (IRE1) 2item
  217. Na /K /Cl- Symporters (NKCCs) 2item
  218. GABAA Receptors 1 item
  219. Phospholipases 1 item
  220. Monoamine oxidases (MAOs) 1 item
  221. Organic anion transporters (OATs) 1 item
  222. TRP Channel 1 item
  223. RNA Polymerases 2item
  224. Norepinephrine transporter 1 item
  225. 5-HT Transporters 3item
  226. Xanthine oxidoreductases 1 item
  227. Dihydroorotate dehydrogenase 1 item
  228. Histone Demethylases 1 item
  229. MNK 2item
  230. 5-Lipoxygenases 1 item
  231. NO Donors / Precursors 2item
  232. CB2 Receptors 1 item
  233. HIV-1 reverse transcriptase 1 item
  234. IL Receptors 2item
  235. CCL2 1 item
  236. Noradrenaline reuptake 1 item
  237. Norepinephrine transporters 1 item
  238. Calcium-Activated Potassium (KCa) Channels 2item
  239. AChE 3item
  240. Insulin Receptors 1 item
  241. IRG-1R 1 item
  242. cAMP 1 item
  243. Sulfonylurea receptors 1 item
  244. Cdc2-like kinase (Clk) 1 item
  245. eEF-2 1 item
  246. Inward Rectifier Potassium (Kir) Channels 3item
  247. Cdc7 1 item
  248. CMV 1 item
  249. ZAP-70 1 item
  250. Catechol O-Methyltransferase (COMT) 2item
  251. fibrinolysis 1 item
  252. Angiotensin AT1 Receptors 1 item
  253. D4 Receptors 1 item
  254. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  255. NMDA receptor 1 item
  256. HBV Proteases 1 item
  257. Hydroxylases 2item
  258. Flk-1 1 item
  259. Papains 1 item
  260. Protein Arginine Methyltransferases 1 item
  261. IMPDH 1 item
  262. Na /Ca2 Exchangers (NCXs) 1 item
  263. NAE 2item
  264. Ubiquitin-activating Enzyme E1 2item
  265. SUMOylation 1 item
  266. ATGL 1 item
  267. BACE 1 item
  268. Cytidine deaminases 1 item
  269. angiogenesis 1 item
  270. Glucagon Receptors 1 item
  271. 15-PGDH 1 item
  272. DPP-4 5item
  273. c-RET 3item
  274. Nonstructural protein 5B (NS5B) 1 item
  275. p70 rsk 3item
  276. voltage-gated chloride channels 1 item
  277. FPTase 1 item
  278. Microtubule/Tubulin 1 item
  279. VEGFR3/FLT4 1 item
  280. NTRK1/TRKA 1 item
  281. CSF-1R/c-Fms 1 item
  282. Tryptophan hydroxylases (TPH) 2item
  283. ADAMs 1 item
  284. NMPRTase 1 item
  285. Bfl-1 1 item
  286. TAM kinase 1 item
  287. p53-MDM2 interaction 1 item
  288. nuclear export 1 item
  289. CRM1 1 item
  290. PTP 1 item
  291. KDR 2item
  292. Fyn kinase 1 item
  293. Trypsin-like protease 1 item
  294. AXL 1 item
  295. Glyoxalase I 1 item
  296. ERAD 1 item
  297. Dipeptidyl-peptidase II 1 item
  298. p53 5item
  299. metalloprotease 1 item
  300. HDAC 2item
  301. 5-HT receptors 1 item
  302. sodium channel 3item
  303. c-Fms tyrosine kinase 1 item
  304. human lyase 1 item
  305. insulin 1 item
  306. Ub-conjugating enzyme (E2) complex 1 item
  307. Smoothened receptor 1 item
  308. cysteine protease 2item
  309. IKK 1 item
  310. MSK 1 item
  311. gp120-CD4 interaction 1 item
  312. HCV polymerase 2item
  313. Ftase 1 item
  314. PC-PLC 2item
  315. Elastases 1 item
  316. Mer tyrosine kinase 1 item
  317. Hec1 1 item
  318. neprilysin 1 item
  319. GLI 1 item
  320. decarboxylase 1 item
  321. HMGCR 1 item
  322. ErbB-2 1 item
  323. adrenergic receptor 2item
  324. 5-HT4 Receptor 1 item
  325. sterol demethylase 1 item
  326. PDK-1 1 item
  327. GAPDH 1 item
  328. Histone Acetyltransferases (HATs) 2item
  329. complex I of the mitochondrial electron transport chain 1 item
  330. F1 Fo-ATPase 1 item
  331. Prk 1 item
  332. potassium channel 1 item
  333. calcium channel 1 item
  334. Ribonucleotide Reductases 1 item
  335. Trx 1 item
  336. Tyrosinases 1 item
  337. HSP70 1 item
  338. ICAM 1 item
  339. ITK 1 item
  340. HIF-PH 1 item
  341. NUAK 1 item
  342. Rho 1 item
  343. Ubiquitin E3 Ligases 1 item
  344. DCLK2 1 item
  345. FAAH 1 item
  346. PTK 1 item
  347. integrase 1 item
  348. NOS 2item
  349. TYK2 2item
  350. MUSK 1 item
  351. MAP3K 1 item
  352. GPR3 1 item
  353. Adenosine Deaminases 2item
  354. mitochondrial pyruvate carrier (MPC) 1 item
  355. prolactin secretion 1 item
  356. gonadotropin release 1 item
  357. DprE 1 item
  358. carnitine reabsorption 1 item
  359. Histamine receptors 1 item
  360. GluR 1 item
  361. 5-HT receptor 1 item
  362. dopamine receptors 1 item
  363. AMPA receptor 1 item
  364. 5-alpha Reductases 1 item
  365. Flk1 2item
  366. p21 1 item
  367. Prostaglandin synthesis 1 item
  368. Protein Tyrosine Phosphatases 1 item
  369. alkaline phosphatases 1 item
  370. ATPases 1 item
  371. glutamate release 1 item
  372. PAFR 1 item
  373. Aromatases 2item
  374. DHFR 1 item
  375. GARFT 1 item
  376. FGR 1 item
  377. YES 2item
  378. Fyn 2item
  379. ARG 1 item
  380. Autotaxin 1 item
  381. UCH 1 item
  382. RHA 1 item
  383. HCV NS3-4A protease 1 item
  384. PKD 1 item
  385. Pyruvate kinases 1 item
  386. Thioredoxin Reductases 1 item
  387. enoyl-acyl-carrier protein reductase 1 item
  388. SHIP 1 item
  389. MCL1 1 item
  390. Bcl-w 1 item
  391. glutathione peroxidase 4 1 item
  392. S-adenosylhomocysteine hydrolase 1 item
  393. Rho-kinase 1 item
  394. tropomyosin receptor kinase 1 item
  395. LSD 1 item
  396. DDX3 1 item
  397. PRMT 1 item
  398. ACE 1 item
  399. GLP 1 item
  400. SK 1 item
  401. MST 1 item
  402. PPK 1 item
  403. c-Syk 1 item
  404. CDK1/CyclinB 1 item
  405. NHE 1 item
  406. IDO 2item
  407. Tph 1 item
  408. PIM1 kinase 1 item
  409. phospholipase A2 1 item
  410. reverse transcriptase 1 item
  411. epoxide hydrolase 1 item
  412. Serotonin (5-HT) reuptake 1 item
  413. Cholesterol absorption 1 item
  414. Vascular Disrupting Agents (VDA) 1 item
  415. Androgen Receptor 1 item
  416. Substance P/NK1 Receptor 1 item
  417. gp120/CD4 1 item
  418. ATM 1 item
  419. Sirtuin 1 item
  420. NE 1 item
  421. PIKfyve 1 item
  422. Bax 1 item
  423. Glycogen Phosphorylases 1 item
  424. MTH1 1 item
  425. PTEN 1 item
  426. Insulin Receptor 1 item
  427. NS3/4a Proteases 1 item
  428. Ca2 -ATPases 1 item
  429. p90 S6K 1 item
  430. Dynamins 1 item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acne 1 item
  3. Acute Disseminated Candidiasis 1 item
  4. Acute Kidney Injury 2item
  5. Acute Lung Injury 1 item
  6. Acute Myelogenous Leukemia 5item
  7. Acute Myeloid Leukemia 25item
  8. Acute Renal Failure 1 item
  9. Adrenocortical Carcinoma 4item
  10. Advanced Renal Cell Carcinoma 1 item
  11. Autoimmune Diseases 1 item
  12. Biliary Cancer 1 item
  13. Bladder Cancer 11item
  14. Bladder Carcinoma 4item
  15. Bladder Diseases 2item
  16. B-lymphoid Malignancies 1 item
  17. Brain Injuries Studies 3item
  18. Breast Cancer 113item
  19. Cancer 500item
  20. Candida Peritonitis 1 item
  21. Candidemia 1 item
  22. Castration-resistant Prostate Cancer 1 item
  23. Cervical Cancer 6item
  24. Cholangiocarcinoma 2item
  25. Chronic Lymphocytic Leukemia 8item
  26. Chronic Myeloproliferative Disorders 1 item
  27. Clear Cell Renal Cell Carcinoma 2item
  28. Cocaine-Related Disorders 2item
  29. Colon Cancer 42item
  30. Colon Carcinoma 7item
  31. Colorectal Cancer 40item
  32. Depression 2item
  33. Diabetes 7item
  34. Diffuse Large B-cell Lymphoma 1 item
  35. Dyskinesia 1 item
  36. Dyslipidemia 2item
  37. Epilepsy 4item
  38. Erectile Dysfunction 4item
  39. Friedreich's Ataxia 2item
  40. Fungal Infection 1 item
  41. Fungi 1 item
  42. Glioblastoma 30item
  43. Glioma 17item
  44. HCV 4item
  45. Heart Failure 3item
  46. Hepatic Cancer 2item
  47. Hepatitis C 4item
  48. Hepatocellular Carcinoma 7item
  49. HIV 13item
  50. HIV Infections 9item
  51. Hypercholesterolemia 3item
  52. Immunological Diseases 1 item
  53. Inflammation 1 item
  54. Inflammatory Bowel Disease 1 item
  55. Inflammatory Diseases 15item
  56. Influenza 3item
  57. Kidney Injury Studies 2item
  58. Leukemia 24item
  59. Liver Cancer 3item
  60. Lung Cancer 40item
  61. Lung Carcinoma 4item
  62. Lymphoma 28item
  63. Mantle Cell Lymphoma 2item
  64. Medulloblastoma 1 item
  65. Melanoma 31item
  66. Mixed Lineage Leukemia 3item
  67. Multiple Myeloma 21item
  68. Myelofibrosis 2item
  69. Myeloma 6item
  70. Neuroblastoma 13item
  71. Neurocognitive Disorders 1 item
  72. Neuronal Protection 1 item
  73. Non-small Cell Lung Cancer 26item
  74. Non-small Cell Lung Carcinoma 2item
  75. Obsessive-Compulsive Disorder 1 item
  76. Osteoporosis 2item
  77. Ovarian Cancer 34item
  78. Pancreatic Cancer 47item
  79. Pancreatic Carcinoma 3item
  80. Prostate Cancer 50item
  81. Psoriasis 4item
  82. Psoriasis Vulgaris 1 item
  83. Pulmonary Arterial Hypertension 2item
  84. Pulmonary Fibrosis 2item
  85. Renal Cancer 4item
  86. Renal Cell Carcinoma 8item
  87. Rheumatoid Arthritis 14item
  88. Sarcoma 1 item
  89. Schizophrenia 8item
  90. Sleep Disorders 2item
  91. Soft Tissue Sarcoma 1 item
  92. Squamous Cell Carcinoma 2item
  93. Testicular Cancer 2item
  94. Thyroid Cancer 6item
  95. Tuberculosis 1 item
  96. Type 2 Diabetes 12item