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  • Search results for: 'mutant idh1 inhibitor'

Search results for: 'mutant idh1 inhibitor'

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  1. LKB1 (AAK1 dual inhibitor)
    A3556 LKB1 (AAK1 dual inhibitor)
    Target: Pim
    Summary: Pim-1 kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥34.8 mg/mL
  2. AKT inhibitor VIII
    A3149 AKT inhibitor VIII
     2 Citation
    Target: Akt
    Summary: Allosteric Akt kinase inhibitor
      insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL
  3. GSK126
    A3446 GSK126
     5 Citation
    Target: EZH2
    Summary: EZH2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥4.38 mg/mL
  4. Aurora A Inhibitor I
    A4126 Aurora A Inhibitor I
    Target: Aurora Kinases
    Summary: Aurora A inhibitor
      ≥29.4 mg/mL
  5. K-Ras(G12C) inhibitor 6
    B3694 K-Ras(G12C) inhibitor 6
    Target: KRAS G12C
    Summary: K-Ras (G12C) inhibitor
      insoluble in H2O; insoluble in EtOH; ≥20.25 mg/mL
  6. FMK
    A3420 FMK
    Target: Ribosomal s6 kinases (RSK)
    Summary: RSK inhibitor
      insoluble in H2O; ≥17.1 mg/mL
  7. Marimastat
    A4049 Marimastat
     1 Citation
    Target: MMP
    Summary: MMPs inhibitor,board spectrum
      ≥2.8 mg/mL
  8. CUDC-907
    A4097 CUDC-907
    Target: Histone Deacetylases (HDACs)|PI3K
    Summary: Potent PI3K/HDAC inhibitor
      ≥25.45 mg/mL
  9. PF-543
    A3717 PF-543
     1 Citation
    Target: Sphingosine kinases (SphKs)
    Summary: SphK1 inhibitor,cell-permeate,potent and selective
      ≥23.3 mg/mL
  10. MC1568
    A4094 MC1568
     3 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: Class II HDAC inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥15.7 mg/mL

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Category
  1. Signaling Pathways 422item
  2. Lab Reagents 1 item
Reversibility
  1. Reversible 24item
  2. Irreversible 16item
Target
  1. Caspases 3item
  2. Cyclin-Dependent Kinases 20item
  3. Proteasome 8item
  4. Cathepsins 2item
  5. Histone Deacetylases (HDACs) 21item
  6. Inhibitor of apoptosis proteins (IAP) 2item
  7. Akt 5item
  8. Bcl-2 4item
  9. PI3K 19item
  10. CXCR 1 item
  11. Raf 8item
  12. Aurora Kinases 11item
  13. Bcl-xl 2item
  14. CSF-1R 2item
  15. Glycoproteins 1 item
  16. p97 1 item
  17. MDM2 1 item
  18. EZH2 5item
  19. mTOR 10item
  20. Bromodomains 4item
  21. MMP 3item
  22. Thymidine Phosphorylases 1 item
  23. Androgen Receptors 2item
  24. DT-diaphorases 1 item
  25. FLT3 6item
  26. GSK-3 4item
  27. P-glycoprotein (P-gp) 5item
  28. PLK 6item
  29. Chk 5item
  30. ULK1 1 item
  31. Eph Receptors 3item
  32. VEGFR 22item
  33. PDGFR 15item
  34. c-Kit 6item
  35. RET 3item
  36. Bromodomain-containing proteins(BRDs) 1 item
  37. Phosphodiesterases (PDEs) 2item
  38. Mcl-1 4item
  39. Thymidylate Synthase 2item
  40. p38 3item
  41. 3-phosphoglycerate dehydrogenase 1 item
  42. JNK 1 item
  43. SGK 2item
  44. Bcr-Abl 5item
  45. MEK 11item
  46. PORCN 1 item
  47. DOT1L 3item
  48. FGFR 8item
  49. Insulin-like growth factor receptors(IGFRs) 1 item
  50. Pim 4item
  51. Sir2-like Family Deacetylases (Sirtuins) 2item
  52. Deubiquitinating enzymes (DUBs) 3item
  53. Smoothened 4item
  54. Ribosomal s6 kinases (RSK) 1 item
  55. MET 7item
  56. Src 4item
  57. Trk Receptors 4item
  58. Integrins 1 item
  59. Aminopeptidases 1 item
  60. STAT 7item
  61. Microtubules/Tubulins 4item
  62. EGFR 14item
  63. Hedgehog 1 item
  64. PAK 3item
  65. Hypoxia Inducible Factors (HIFs) 2item
  66. FAK 5item
  67. BMP and Other Activin Receptors 2item
  68. JAK 7item
  69. p300 1 item
  70. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  71. Syk 4item
  72. EZH1 1 item
  73. DNA-PK 4item
  74. HSP90 10item
  75. Gutathione S-transferase 1 item
  76. eIF4E/eIF3G interaction 1 item
  77. Notch 1 item
  78. TNKS 1 item
  79. Topoisomerases 6item
  80. Cytochrome P450 (CYP450) 4item
  81. Ksp 1 item
  82. ErbB 2item
  83. DNA Methyltransferases 3item
  84. Survivin 1 item
  85. ERK 3item
  86. HMG-CoA Reductases 2item
  87. Vacuolar-type ATPase 1 item
  88. c-MET 7item
  89. BMI-1 1 item
  90. PKC 5item
  91. Calpains 2item
  92. Ubiquitin-specific proteases 1 item
  93. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  94. SMYD2 1 item
  95. CREBBP 1 item
  96. EP300 1 item
  97. Lyn 1 item
  98. RAD51 1 item
  99. HER2 1 item
  100. Pyk2 3item
  101. USP 1 item
  102. 5-HT2 Receptors 1 item
  103. Insulin and Insulin-like Receptors 1 item
  104. PARP 1 item
  105. ALK 4item
  106. ROS1 2item
  107. Sphingosine kinases (SphKs) 1 item
  108. KRAS G12C 1 item
  109. Monocarboxylate transporters (MCTs) 1 item
  110. Dehydrogenase 1 item
  111. PKG 1 item
  112. PKA 1 item
  113. Myosin light chain kinases (MLCKs) 1 item
  114. D1 and D5 Receptors 1 item
  115. D2 Receptors 1 item
  116. D3 Receptors 1 item
  117. Valosin-containing protein (VCP) 1 item
  118. MELK 1 item
  119. Insulin-like growth factors (IGFs) 1 item
  120. Integrin-ligand interactions 1 item
  121. CSF1R 1 item
  122. Bromodomain and Extra-Terminal motif (BET) 1 item
  123. MK2 2item
  124. Angiotensin-Converting Enzymes (ACEs) 1 item
  125. Tie-2 3item
  126. RSK 1 item
  127. p70 S6K 1 item
  128. Autophagy 2item
  129. ATM/ATR 6item
  130. COX 2item
  131. Heparanases 1 item
  132. CK1 1 item
  133. IDH2 1 item
  134. CK2 1 item
  135. HIPK2 1 item
  136. HIPK3 1 item
  137. HIV Integrases 1 item
  138. PRAK 1 item
  139. MAPKAP-K2 1 item
  140. Guanine nucleotide exchange factors (GEFs) 1 item
  141. 20S proteasomal chymotrypsin 1 item
  142. Geranylgeranyltransferase I 1 item
  143. Farnesyltransferase 1 item
  144. Nampt 2item
  145. eIF4F 1 item
  146. Cdc42 1 item
  147. Glutaminases 1 item
  148. Carbonic Anhydrases 1 item
  149. Ron 1 item
  150. BLM 1 item
  151. Aldehyde Dehydrogenases 1 item
  152. Synthases/Synthetases 2item
  153. P110 1 item
  154. Hck 1 item
  155. Inositol-requiring enzyme 1 (IRE1) 1 item
  156. DYRK 1 item
  157. Norepinephrine transporter 1 item
  158. 5-HT Transporters 1 item
  159. Histone Demethylases 1 item
  160. HIV-1 reverse transcriptase 1 item
  161. Insulin Receptors 1 item
  162. IRG-1R 1 item
  163. cAMP 1 item
  164. Sulfonylurea receptors 1 item
  165. eEF-2 1 item
  166. Cdc7 1 item
  167. CMV 1 item
  168. ZAP-70 1 item
  169. Catechol O-Methyltransferase (COMT) 1 item
  170. fibrinolysis 1 item
  171. D4 Receptors 1 item
  172. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  173. Flk-1 1 item
  174. Papains 1 item
  175. Protein Arginine Methyltransferases 1 item
  176. NAE 2item
  177. Ubiquitin-activating Enzyme E1 1 item
  178. SUMOylation 1 item
  179. Cytidine deaminases 1 item
  180. angiogenesis 1 item
  181. DPP-4 1 item
  182. TAM kinase 1 item
  183. p53-MDM2 interaction 1 item
  184. nuclear export 1 item
  185. CRM1 1 item
  186. AXL 1 item
  187. human lyase 1 item
  188. Ub-conjugating enzyme (E2) complex 1 item
  189. MCL1 1 item
  190. Bcl-w 1 item
  191. tropomyosin receptor kinase 1 item
  192. LSD 1 item
  193. SK 1 item
  194. IDO 1 item
  195. Substance P/NK1 Receptor 1 item
Reported Experiments
  1. Animal Experiments 388item
  2. Cell Experiments 237item