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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Items 31-40 of 120

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  1. Ruxolitinib (INCB018424)
    A3012 Ruxolitinib (INCB018424)
     4 Citation
    Target: JAK
    Summary: JAK inhibitor
      insoluble in H2O; ≥15.32 mg/mL
  2. LGK-974
    B2307 LGK-974
     1 Citation
    Summary: PORCN inhibitor,potent and specific
      insoluble in H2O; ≥19.8 mg/mL
  3. CGK733
    A8624 CGK733
    Target: ATM/ATR
    Summary: ATM/ATR inhibitor,potent and selective
      ≥27.8 mg/mL
  4. GSK2126458
    A8556 GSK2126458
     1 Citation
    Target: PI3K|mTOR
    Summary: PI3K/mTOR inhibitor
      ≥25.3 mg/mL
  5. AZD8330
    A8374 AZD8330
    Target: MEK
    Summary: MEK 1/2 inhibitor
      ≥23.05 mg/mL
  6. Abiraterone acetate
    A8202 Abiraterone acetate
    Target: Cytochrome P450 (CYP450)
    Summary: Cytochrome p450 17a1 inhibitor
      insoluble in H2O; ≥11.22 mg/mL
  7. 3-Methyladenine
    A8353 3-Methyladenine
     3 Citation
    Target: PI3K
    Summary: Class III PI3K inhibitor
      ≥5 mg/mL
  8. THZ2
    A8717 THZ2
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK7 inhibitor
      ≥28.3 mg/mL
  9. MK-2206 dihydrochloride
    A3010 MK-2206 dihydrochloride
     21 Citation
    Target: Akt
    Summary: Akt1/2/3 inhibitor
      insoluble in EtOH; ≥12.01 mg/mL
  10. BYL-719
    A8346 BYL-719
     1 Citation
    Target: PI3K
    Summary: Selective PI3Kα inhibitor
      ≥22.07 mg/mL

Items 31-40 of 120

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  1. Category Signaling Pathways Remove This Item
  2. Related Disease Breast Cancer Remove This Item
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Category
  1. Proteases 10item
  2. Apoptosis 5item
  3. Chromatin/Epigenetics 19item
  4. Metabolism 8item
  5. MAPK Signaling 6item
  6. Tyrosine Kinase 22item
  7. DNA Damage/DNA Repair 17item
  8. PI3K/Akt/mTOR Signaling 14item
  9. Microbiology & Virology 1 item
  10. Cell Cycle/Checkpoint 14item
  11. Ubiquitination/ Proteasome 6item
  12. JAK/STAT Signaling 10item
  13. TGF-β / Smad Signaling 3item
  14. Angiogenesis 2item
  15. GPCR/G protein 3item
  16. Stem Cell 5item
  17. Membrane Transporter/Ion Channel 1 item
  18. Endocrinology and Hormones 2item
  19. Neuroscience 1 item
  20. Others 4item
  21. Immunology/Inflammation 1 item
Specificity
  1. Selective 115item
Reversibility
  1. Reversible 9item
  2. Irreversible 3item
Target
  1. Cyclin-Dependent Kinases 6item
  2. Proteasome 2item
  3. Cathepsins 1 item
  4. Histone Deacetylases (HDACs) 10item
  5. Inhibitor of apoptosis proteins (IAP) 1 item
  6. Akt 3item
  7. Bcl-2 2item
  8. PI3K 8item
  9. CXCR 3item
  10. Aurora Kinases 4item
  11. Bcl-xl 2item
  12. CSF-1R 1 item
  13. EZH2 2item
  14. mTOR 5item
  15. Bromodomains 1 item
  16. DT-diaphorases 1 item
  17. FLT3 2item
  18. P-glycoprotein (P-gp) 1 item
  19. PLK 1 item
  20. Chk 1 item
  21. VEGFR 9item
  22. PDGFR 4item
  23. c-Kit 3item
  24. Mcl-1 2item
  25. Thymidylate Synthase 1 item
  26. p38 1 item
  27. 3-phosphoglycerate dehydrogenase 1 item
  28. Bcr-Abl 1 item
  29. MEK 5item
  30. PORCN 1 item
  31. FGFR 2item
  32. Pim 1 item
  33. Smoothened 1 item
  34. MET 1 item
  35. Src 1 item
  36. Trk Receptors 1 item
  37. STAT 2item
  38. Microtubules/Tubulins 1 item
  39. EGFR 8item
  40. FAK 1 item
  41. BMP and Other Activin Receptors 1 item
  42. JAK 2item
  43. Syk 1 item
  44. HSP90 5item
  45. Topoisomerases 1 item
  46. Cytochrome P450 (CYP450) 3item
  47. Ksp 1 item
  48. ErbB 1 item
  49. Survivin 1 item
  50. c-MET 1 item
  51. PKC 2item
  52. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  53. HER2 2item
  54. PARP 1 item
  55. ALK 1 item
  56. ROS1 1 item
  57. D1 and D5 Receptors 1 item
  58. D2 Receptors 1 item
  59. D3 Receptors 1 item
  60. MELK 1 item
  61. CSF1R 1 item
  62. Autophagy 1 item
  63. ATM/ATR 2item
  64. COX 1 item
  65. Heparanases 1 item
  66. CK2 1 item
  67. HIPK2 1 item
  68. HIPK3 1 item
  69. PRAK 1 item
  70. MAPKAP-K2 1 item
  71. 20S proteasomal chymotrypsin 1 item
  72. Geranylgeranyltransferase I 1 item
  73. Farnesyltransferase 1 item
  74. Carbonic Anhydrases 1 item
  75. FoxM1 1 item
  76. Insulin Receptors 1 item
  77. IRG-1R 1 item
  78. eEF-2 1 item
  79. D4 Receptors 1 item
  80. DPP-4 1 item
  81. Aromatases 2item
Reported Experiments
  1. Animal Experiments 113item
  2. Cell Experiments 70item