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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Items 31-40 of 541

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  1. GDC-0941
    A8210 GDC-0941
     10 Citation
    Target: PI3K
    Summary: PI3K inhibitor,potent and selective
      ≥25.7 mg/mL
  2. DMAT
    A3368 DMAT
     2 Citation
    Target: Pim|CK2|HIPK2|HIPK3
    Summary: CK2 inhibitor,potent and selective
      ≥23.85 mg/mL
  3. CHIR-99021 (CT99021)
    A3011 CHIR-99021 (CT99021)
     2 Citation
    Target: GSK-3
    Summary: GSK-3 inhibitor, Cell-permeable, ATP-competitive
      ≥23.27 mg/mL
  4. P005091
    A3023 P005091
     1 Citation
    Target: Ubiquitin-specific proteases
    Summary: Ubiquitin-specific protease 7 (USP7) inhibitor
      insoluble in H2O; insoluble in EtOH; ≥17.4 mg/mL
  5. YO-01027 (Dibenzazepine, DBZ)
    A4018 YO-01027 (Dibenzazepine, DBZ)
     1 Citation
    Summary: γ-secretase inhibitor
      ≥23.17 mg/mL
  6. M344
    A4105 M344
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,potent and cell-permeable
  7. Deltarasin
    A3358 Deltarasin
    Target: Phosphodiesterases (PDEs)
    Summary: KRAS-PDEδ interaction inhibitor
      Soluble in DMSO
  8. ALW-II-41-27
    A3165 ALW-II-41-27
     1 Citation
    Target: Eph Receptors
    Summary: Eph receptor inhibitor
      ≥60.8 mg/mL
  9. GSK1324726A
    B1013 GSK1324726A
    Target: Bromodomains
    Summary: BET proteins inhibitor
  10. D4476
    A3342 D4476
     1 Citation
    Target: CK1
    Summary: CK1/ALK5 inhibitor,specific and cell permeable
      insoluble in H2O; ≥19.9 mg/mL

Items 31-40 of 541

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  1. Category Signaling Pathways Remove This Item
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Category
  1. Proteases 33item
  2. Apoptosis 39item
  3. Chromatin/Epigenetics 83item
  4. Metabolism 32item
  5. MAPK Signaling 27item
  6. Tyrosine Kinase 109item
  7. DNA Damage/DNA Repair 54item
  8. PI3K/Akt/mTOR Signaling 50item
  9. Microbiology & Virology 4item
  10. Cell Cycle/Checkpoint 71item
  11. Ubiquitination/ Proteasome 29item
  12. JAK/STAT Signaling 35item
  13. TGF-β / Smad Signaling 22item
  14. Angiogenesis 6item
  15. GPCR/G protein 9item
  16. Stem Cell 24item
  17. Membrane Transporter/Ion Channel 6item
  18. Endocrinology and Hormones 4item
  19. Neuroscience 5item
  20. Others 28item
  21. Immunology/Inflammation 4item
Specificity
  1. Selective 429item
  2. Non-Selective 2item
Reversibility
  1. Reversible 28item
  2. Irreversible 22item
Target
  1. Caspases 3item
  2. Cyclin-Dependent Kinases 25item
  3. Proteasome 9item
  4. Cathepsins 2item
  5. Histone Deacetylases (HDACs) 24item
  6. Inhibitor of apoptosis proteins (IAP) 2item
  7. Akt 11item
  8. Bcl-2 7item
  9. PI3K 26item
  10. CXCR 2item
  11. Raf 11item
  12. Aurora Kinases 18item
  13. Bcl-xl 2item
  14. CSF-1R 4item
  15. Glycoproteins 1 item
  16. p97 1 item
  17. MDM2 2item
  18. EZH2 5item
  19. mTOR 15item
  20. Bromodomains 5item
  21. MMP 3item
  22. Thymidine Phosphorylases 1 item
  23. Androgen Receptors 3item
  24. DT-diaphorases 1 item
  25. FLT3 12item
  26. GSK-3 5item
  27. P-glycoprotein (P-gp) 5item
  28. PLK 9item
  29. Chk 5item
  30. ULK1 1 item
  31. Eph Receptors 3item
  32. VEGFR 36item
  33. PDGFR 21item
  34. c-Kit 10item
  35. RET 4item
  36. Bromodomain-containing proteins(BRDs) 1 item
  37. Phosphodiesterases (PDEs) 3item
  38. Mcl-1 5item
  39. Thymidylate Synthase 3item
  40. p38 3item
  41. 3-phosphoglycerate dehydrogenase 1 item
  42. JNK 1 item
  43. SGK 2item
  44. Bcr-Abl 8item
  45. MEK 11item
  46. PORCN 1 item
  47. DOT1L 3item
  48. FGFR 13item
  49. Insulin-like growth factor receptors(IGFRs) 1 item
  50. Pim 3item
  51. Liver X receptors (LXRs) 1 item
  52. Sir2-like Family Deacetylases (Sirtuins) 2item
  53. Deubiquitinating enzymes (DUBs) 4item
  54. PP1 1 item
  55. PP2A 1 item
  56. Smoothened 4item
  57. Ribosomal s6 kinases (RSK) 1 item
  58. MET 7item
  59. Src 8item
  60. Trk Receptors 5item
  61. Integrins 1 item
  62. Aminopeptidases 2item
  63. STAT 6item
  64. Microtubules/Tubulins 4item
  65. EGFR 20item
  66. Hedgehog 1 item
  67. ROCK 1 item
  68. PAK 3item
  69. Hypoxia Inducible Factors (HIFs) 2item
  70. FAK 6item
  71. BMP and Other Activin Receptors 2item
  72. JAK 12item
  73. p300 1 item
  74. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  75. Syk 4item
  76. EZH1 1 item
  77. DNA-PK 5item
  78. HSP90 12item
  79. Gutathione S-transferase 1 item
  80. eIF4E/eIF3G interaction 1 item
  81. Notch 1 item
  82. TNKS 1 item
  83. Topoisomerases 9item
  84. Cytochrome P450 (CYP450) 4item
  85. Ksp 1 item
  86. ErbB 5item
  87. DNA Methyltransferases 3item
  88. Survivin 1 item
  89. ERK 4item
  90. HMG-CoA Reductases 2item
  91. Vacuolar-type ATPase 1 item
  92. c-MET 7item
  93. BMI-1 1 item
  94. PKC 10item
  95. Calpains 2item
  96. Ubiquitin-specific proteases 1 item
  97. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  98. SMYD2 1 item
  99. CREBBP 1 item
  100. EP300 1 item
  101. Lyn 1 item
  102. RAD51 2item
  103. HER2 2item
  104. Pyk2 3item
  105. 5-HT2 Receptors 1 item
  106. Insulin and Insulin-like Receptors 2item
  107. PARP 3item
  108. Pyruvate dehydrogenases (PDH) 1 item
  109. ALK 7item
  110. ROS1 2item
  111. Sphingosine kinases (SphKs) 2item
  112. KRAS G12C 1 item
  113. Monocarboxylate transporters (MCTs) 1 item
  114. Dehydrogenase 1 item
  115. PKG 2item
  116. PKA 5item
  117. Myosin light chain kinases (MLCKs) 1 item
  118. D1 and D5 Receptors 1 item
  119. D2 Receptors 1 item
  120. D3 Receptors 1 item
  121. Valosin-containing protein (VCP) 1 item
  122. MELK 1 item
  123. Insulin-like growth factors (IGFs) 1 item
  124. Integrin-ligand interactions 1 item
  125. CSF1R 1 item
  126. Bromodomain and Extra-Terminal motif (BET) 1 item
  127. MK2 2item
  128. Angiotensin-Converting Enzymes (ACEs) 1 item
  129. Tie-2 4item
  130. RSK 2item
  131. p70 S6K 1 item
  132. Autophagy 3item
  133. ATM/ATR 6item
  134. COX 2item
  135. Heparanases 1 item
  136. CK1 1 item
  137. IDH2 1 item
  138. Farnesyl Diphosphate Synthases 1 item
  139. CK2 1 item
  140. HIPK2 1 item
  141. HIPK3 1 item
  142. PRAK 1 item
  143. MAPKAP-K2 1 item
  144. 20S proteasomal chymotrypsin 1 item
  145. Geranylgeranyltransferase I 1 item
  146. Farnesyltransferase 1 item
  147. Nampt 3item
  148. eIF4F 1 item
  149. Cdc42 1 item
  150. Glutaminases 2item
  151. Carbonic Anhydrases 1 item
  152. Ron 1 item
  153. BLM 1 item
  154. Aldehyde Dehydrogenases 1 item
  155. Synthases/Synthetases 2item
  156. P110 1 item
  157. Hck 1 item
  158. Inositol-requiring enzyme 1 (IRE1) 1 item
  159. Norepinephrine transporter 1 item
  160. 5-HT Transporters 1 item
  161. FoxM1 1 item
  162. Apoptosis Inducers 1 item
  163. MNK 1 item
  164. HIV-1 reverse transcriptase 1 item
  165. Calcium-Activated Potassium (KCa) Channels 1 item
  166. Insulin Receptors 1 item
  167. IRG-1R 1 item
  168. cAMP 1 item
  169. Sulfonylurea receptors 1 item
  170. eEF-2 1 item
  171. Cdc7 1 item
  172. CMV 1 item
  173. ZAP-70 1 item
  174. Catechol O-Methyltransferase (COMT) 1 item
  175. fibrinolysis 1 item
  176. D4 Receptors 1 item
  177. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  178. Flk-1 1 item
  179. Papains 1 item
  180. Protein Arginine Methyltransferases 1 item
  181. NAE 2item
  182. Ubiquitin-activating Enzyme E1 1 item
  183. SUMOylation 1 item
  184. Cytidine deaminases 1 item
  185. angiogenesis 1 item
  186. DPP-4 1 item
  187. PP4 1 item
  188. c-RET 2item
  189. p70 rsk 2item
  190. VEGFR3/FLT4 1 item
  191. NTRK1/TRKA 1 item
  192. CSF-1R/c-Fms 1 item
  193. NMPRTase 1 item
  194. Bfl-1 1 item
  195. TAM kinase 1 item
  196. p53-MDM2 interaction 1 item
  197. nuclear export 1 item
  198. CRM1 1 item
  199. KDR 2item
  200. AXL 1 item
  201. Glyoxalase I 1 item
  202. p53 4item
  203. HDAC 1 item
  204. human lyase 1 item
  205. insulin 1 item
  206. Ub-conjugating enzyme (E2) complex 1 item
  207. Smoothened receptor 1 item
  208. HDM2 ubiquitin ligase 1 item
  209. Hec1 1 item
  210. GLI 1 item
  211. ErbB-2 1 item
  212. PDK-1 1 item
  213. Prk 1 item
  214. Ribonucleotide Reductases 1 item
  215. Trx 1 item
  216. HSP70 1 item
  217. TYK2 1 item
  218. MUSK 1 item
  219. MAP3K 1 item
  220. Adenosine Deaminases 1 item
  221. Flk1 2item
  222. DHFR 1 item
  223. GARFT 1 item
  224. RHA 1 item
  225. MCL1 1 item
  226. Bcl-w 1 item
  227. tropomyosin receptor kinase 1 item
  228. LSD 1 item
  229. DDX3 1 item
  230. SK 1 item
  231. PPK 1 item
  232. c-Syk 1 item
  233. CDK1/CyclinB 1 item
  234. IDO 1 item
  235. PIM1 kinase 1 item
  236. phospholipase A2 1 item
  237. Substance P/NK1 Receptor 1 item
  238. Bax 1 item
Reported Experiments
  1. Animal Experiments 499item
  2. Cell Experiments 343item