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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Items 61-70 of 755

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  1. S-Ruxolitinib (INCB018424)
    A4149 S-Ruxolitinib (INCB018424)
    Target: JAK
    Summary: JAK1/2 inhibitor,potent and selective
      Soluble in DMSO
  2. GSK1324726A
    B1013 GSK1324726A
    Target: Bromodomains
    Summary: BET proteins inhibitor
  3. DAPT (GSI-IX)
    A8200 DAPT (GSI-IX)
     6 Citation
    Summary: γ-secretase inhibitor,potent and specific
      ≥21.62 mg/mL
  4. Boc-D-FMK
    A1904 Boc-D-FMK
     1 Citation
    Target: Caspases
    Summary: Pan-caspase inhibitor
      insoluble in H2O; ≥11.65 mg/mL
  5. TBB
    A3861 TBB
     1 Citation
    Target: CK2
    Summary: Casein kinase-2 (CK2) inhibitor
      insoluble in H2O; ≥159.2 mg/mL
  6. INCB024360 analogue
    A3493 INCB024360 analogue
    Summary: potent and selective inhibitor of IDO1
      ≥13.55 mg/mL
  7. Z-DEVD-FMK
    A1920 Z-DEVD-FMK
     12 Citation
    Target: Caspases
    Summary: Caspase-3 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥60 mg/mL
  8. MG-115
    A2612 MG-115
     1 Citation
    Target: Proteasome
    Summary: Potent reversible proteasome inhibitor
      ≥23.08 mg/mL
  9. Thioridazine HCl
    A8537 Thioridazine HCl
    Target: Cytochrome P450 (CYP450)|D1 and D5 Receptors|D2 Receptors|D3 Receptors|D4 Receptors
    Summary: Calcium channel protein inhibitor
  10. MI-2
    A3602 MI-2
    Target: Menin-MLL
    Summary: Menin-MLL Inhibitor
      insoluble in H2O; ≥15.1 mg/mL

Items 61-70 of 755

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Category
  1. Proteases 68item
  2. Apoptosis 48item
  3. Chromatin/Epigenetics 97item
  4. Metabolism 74item
  5. MAPK Signaling 31item
  6. Tyrosine Kinase 97item
  7. DNA Damage/DNA Repair 61item
  8. PI3K/Akt/mTOR Signaling 60item
  9. Microbiology & Virology 33item
  10. Cell Cycle/Checkpoint 69item
  11. Ubiquitination/ Proteasome 27item
  12. JAK/STAT Signaling 36item
  13. TGF-β / Smad Signaling 31item
  14. Angiogenesis 5item
  15. GPCR/G protein 18item
  16. Stem Cell 23item
  17. Membrane Transporter/Ion Channel 25item
  18. Cancer Biology 2item
  19. Endocrinology and Hormones 13item
  20. Neuroscience 33item
  21. Other Signal Transduction 2item
  22. Others 61item
  23. Immunology/Inflammation 14item
  24. Cardiovascular 1 item
  25. Vitamin D Related 1 item
Specificity
  1. Selective 460item
  2. Non-Selective 3item
Reversibility
  1. Reversible 34item
  2. Irreversible 25item
Target
  1. Caspases 6item
  2. Cyclin-Dependent Kinases 21item
  3. Proteasome 11item
  4. Cathepsins 5item
  5. Histone Deacetylases (HDACs) 25item
  6. Akt 11item
  7. Bcl-2 8item
  8. PI3K 27item
  9. CXCR 3item
  10. Raf 10item
  11. Aurora Kinases 18item
  12. Bcl-xl 3item
  13. CSF-1R 4item
  14. Glycoproteins 1 item
  15. p97 1 item
  16. Gap Junctions 1 item
  17. MDM2 1 item
  18. EZH2 3item
  19. mTOR 16item
  20. Bromodomains 5item
  21. AP-1 1 item
  22. MMP 6item
  23. Thymidine Phosphorylases 1 item
  24. Androgen Receptors 3item
  25. Peptidylprolyl isomerases 1 item
  26. Acyl coenzyme A: cholesterol acyltransferases 1 item
  27. Myosin II ATPases 1 item
  28. DT-diaphorases 1 item
  29. Voltage-gated Potassium (KV) Channels 1 item
  30. MER 1 item
  31. FLT3 16item
  32. GSK-3 6item
  33. Factor Xa 4item
  34. P-glycoprotein (P-gp) 3item
  35. PLK 9item
  36. Chk 4item
  37. Eph Receptors 2item
  38. VEGFR 28item
  39. PDGFR 19item
  40. c-Kit 9item
  41. RET 2item
  42. IRAK 2item
  43. Bromodomain-containing proteins(BRDs) 1 item
  44. Phosphodiesterases (PDEs) 12item
  45. Mcl-1 5item
  46. Hydrolase 1 item
  47. Thymidylate Synthase 3item
  48. p38 6item
  49. PKB 1 item
  50. JNK 1 item
  51. Bcr-Abl 10item
  52. MEK 8item
  53. PORCN 1 item
  54. DOT1L 1 item
  55. FGFR 10item
  56. Nrf2 1 item
  57. Pim 3item
  58. Liver X receptors (LXRs) 1 item
  59. Sir2-like Family Deacetylases (Sirtuins) 1 item
  60. Voltage-gated Sodium (NaV) Channels 1 item
  61. Deubiquitinating enzymes (DUBs) 2item
  62. PP1 1 item
  63. PP2A 1 item
  64. Smoothened 1 item
  65. Neuraminidases (NA) 1 item
  66. MET 5item
  67. Src 14item
  68. Trk Receptors 4item
  69. Aminopeptidases 1 item
  70. NMDA Receptors 1 item
  71. STAT 6item
  72. Microtubules/Tubulins 1 item
  73. Estrogen and Related Receptors 1 item
  74. EGFR 18item
  75. Reverse Transcriptases 5item
  76. ROCK 7item
  77. Hypoxia Inducible Factors (HIFs) 1 item
  78. FAK 3item
  79. JAK 17item
  80. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  81. Syk 4item
  82. EZH1 1 item
  83. DNA-PK 6item
  84. HSP90 8item
  85. AMPK 1 item
  86. CFTR 2item
  87. Topoisomerases 11item
  88. Cytochrome P450 (CYP450) 7item
  89. Ksp 1 item
  90. Renin 1 item
  91. ErbB 4item
  92. Toll-like receptors (TLRs) 2item
  93. Actin 2item
  94. Serine Proteases 1 item
  95. DNA Methyltransferases 1 item
  96. ERK 6item
  97. HMG-CoA Reductases 4item
  98. c-MET 6item
  99. PKC 12item
  100. Calpains 3item
  101. Ca2 /calmodulin-dependent protein kinases (CaMKs) 4item
  102. Protease-Activated Receptors 1 item
  103. Lyn 1 item
  104. RAD51 1 item
  105. HER2 1 item
  106. Pyk2 2item
  107. 5-HT2 Receptors 3item
  108. LRRK2 5item
  109. Voltage-gated Calcium Channels (CaV) 1 item
  110. DGAT 1 item
  111. Insulin and Insulin-like Receptors 4item
  112. PARP 6item
  113. Pyruvate dehydrogenases (PDH) 1 item
  114. ALK 6item
  115. Sphingosine kinases (SphKs) 2item
  116. Monocarboxylate transporters (MCTs) 1 item
  117. CETP 1 item
  118. PKG 2item
  119. PKA 5item
  120. Myosin light chain kinases (MLCKs) 2item
  121. D1 and D5 Receptors 1 item
  122. D2 Receptors 3item
  123. D3 Receptors 2item
  124. 5-HT1 Receptors 2item
  125. 5-HT7 Receptors 1 item
  126. Lactate Dehydrogenases (LDH) 2item
  127. MK2 2item
  128. Angiotensin-Converting Enzymes (ACEs) 3item
  129. Tie-2 3item
  130. RSK 2item
  131. phosphatases 1 item
  132. Autophagy 3item
  133. ATM/ATR 5item
  134. COX 10item
  135. CK1 1 item
  136. Farnesyl Diphosphate Synthases 1 item
  137. CK2 3item
  138. HIPK2 1 item
  139. HIPK3 1 item
  140. HIV Integrases 1 item
  141. Squalene epoxidases 1 item
  142. PRAK 1 item
  143. MAPKAP-K2 1 item
  144. 20S proteasomal chymotrypsin 1 item
  145. Geranylgeranyltransferase I 1 item
  146. Farnesyltransferase 1 item
  147. Nampt 3item
  148. eIF4F 1 item
  149. Cdc42 1 item
  150. SRPK1 1 item
  151. P2X Receptors 1 item
  152. Glutaminases 2item
  153. Carbonic Anhydrases 6item
  154. Ron 1 item
  155. G9a 1 item
  156. BLM 1 item
  157. HSV 1 item
  158. NADPH Oxidases 3item
  159. Calcium-activated chloride channels (CaCC) 1 item
  160. GPR35 1 item
  161. Aldehyde Dehydrogenases 1 item
  162. Synthases/Synthetases 2item
  163. Histamine H1 Receptors 2item
  164. Na /K ATPases 2item
  165. P110 1 item
  166. Hck 2item
  167. Inositol-requiring enzyme 1 (IRE1) 1 item
  168. Na /K /Cl- Symporters (NKCCs) 2item
  169. GABAA Receptors 2item
  170. Phospholipases 1 item
  171. RNA Polymerases 1 item
  172. DYRK 1 item
  173. Norepinephrine transporter 1 item
  174. 5-HT Transporters 3item
  175. Xanthine oxidoreductases 1 item
  176. Dihydroorotate dehydrogenase 1 item
  177. FoxM1 1 item
  178. MNK 2item
  179. 5-Lipoxygenases 1 item
  180. NO Donors / Precursors 1 item
  181. HIV-1 reverse transcriptase 1 item
  182. IL Receptors 2item
  183. CCL2 1 item
  184. Norepinephrine transporters 1 item
  185. Calcium-Activated Potassium (KCa) Channels 2item
  186. AChE 3item
  187. Insulin Receptors 1 item
  188. IRG-1R 1 item
  189. cAMP 1 item
  190. Sulfonylurea receptors 1 item
  191. eEF-2 1 item
  192. Inward Rectifier Potassium (Kir) Channels 2item
  193. Cdc7 1 item
  194. CMV 1 item
  195. ZAP-70 1 item
  196. Catechol O-Methyltransferase (COMT) 2item
  197. fibrinolysis 1 item
  198. Angiotensin AT1 Receptors 1 item
  199. D4 Receptors 1 item
  200. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  201. NMDA receptor 1 item
  202. HBV Proteases 1 item
  203. Hydroxylases 2item
  204. Flk-1 1 item
  205. Papains 1 item
  206. Protein Arginine Methyltransferases 1 item
  207. IMPDH 1 item
  208. Na /Ca2 Exchangers (NCXs) 1 item
  209. NAE 2item
  210. Ubiquitin-activating Enzyme E1 2item
  211. SUMOylation 1 item
  212. ATGL 1 item
  213. BACE 2item
  214. Cytidine deaminases 1 item
  215. GPR40 1 item
  216. angiogenesis 1 item
  217. Glucagon Receptors 1 item
  218. 15-PGDH 1 item
  219. DPP-4 5item
  220. PP4 1 item
  221. c-RET 3item
  222. Nonstructural protein 5B (NS5B) 1 item
  223. p70 rsk 3item
  224. voltage-gated chloride channels 1 item
  225. FPTase 1 item
  226. Microtubule/Tubulin 1 item
  227. VEGFR3/FLT4 1 item
  228. NTRK1/TRKA 1 item
  229. CSF-1R/c-Fms 1 item
  230. Menin-MLL 2item
  231. Tryptophan hydroxylases (TPH) 2item
  232. ADAMs 1 item
  233. NMPRTase 1 item
  234. Bfl-1 1 item
  235. TAM kinase 1 item
  236. p53-MDM2 interaction 2item
  237. nuclear export 1 item
  238. CRM1 1 item
  239. PTP 1 item
  240. KDR 2item
  241. Fyn kinase 1 item
  242. Abl kinases 1 item
  243. AXL 1 item
  244. Glyoxalase I 1 item
  245. dCTP Pyrophosphatases 1 item
  246. Protein polybromo-1 1 item
  247. SMARCA4 1 item
  248. SMARCA2 1 item
  249. Dipeptidyl-peptidase II 1 item
  250. p53 7item
  251. metalloprotease 1 item
  252. HDAC 2item
  253. KDM 2item
  254. 5-HT receptors 1 item
  255. sodium channel 2item
  256. c-Fms tyrosine kinase 1 item
  257. human lyase 1 item
  258. insulin 1 item
  259. Ub-conjugating enzyme (E2) complex 1 item
  260. Smoothened receptor 1 item
  261. quinone oxidoreductase 1 item
  262. cysteine protease 2item
  263. STK 1 item
  264. HDM2 ubiquitin ligase 1 item
  265. USP1/USF1 complex 1 item
  266. IKK 1 item
  267. MSK 1 item
  268. gp120-CD4 interaction 1 item
  269. HCV polymerase 3item
  270. Ftase 1 item
  271. Subtilisin/Kex2p-like proprotein convertase 1 item
  272. PC-PLC 2item
  273. Elastases 1 item
  274. P97 ATPase 1 item
  275. NTPDases 1 item
  276. Mer tyrosine kinase 1 item
  277. Hec1 1 item
  278. neprilysin 1 item
  279. GLI 1 item
  280. HMGCR 1 item
  281. AAT 1 item
  282. ErbB-2 1 item
  283. adrenergic receptor 2item
  284. 5-HT4 Receptor 1 item
  285. sterol demethylase 1 item
  286. PDK-1 1 item
  287. GAPDH 1 item
  288. telomerase 1 item
  289. Histone Acetyltransferases (HATs) 3item
  290. complex I of the mitochondrial electron transport chain 1 item
  291. F1 Fo-ATPase 1 item
  292. Prk 1 item
  293. potassium channel 1 item
  294. calcium channel 1 item
  295. Ribonucleotide Reductases 1 item
  296. Trx 1 item
  297. Tyrosinases 1 item
  298. HSP70 1 item
  299. ICAM 1 item
  300. ITK 1 item
  301. HIF-PH 1 item
  302. NOD1 1 item
  303. NUAK 1 item
  304. Rho 1 item
  305. Ubiquitin E3 Ligases 1 item
  306. DCLK2 1 item
  307. FAAH 1 item
  308. PTK 1 item
  309. integrase 1 item
  310. L3MBTL 1 item
  311. NOS 2item
  312. MDMX 1 item
  313. TYK2 2item
  314. MUSK 1 item
  315. MAP3K 1 item
  316. GPR3 1 item
  317. Lck 1 item
  318. Adenosine Deaminases 2item
  319. mitochondrial pyruvate carrier (MPC) 1 item
  320. prolactin secretion 1 item
  321. gonadotropin release 1 item
  322. DprE 1 item
  323. carnitine reabsorption 1 item
  324. Histamine receptors 1 item
  325. GluR 1 item
  326. 5-HT receptor 1 item
  327. dopamine receptors 1 item
  328. AMPA receptor 1 item
  329. 5-alpha Reductases 1 item
  330. Flk1 2item
  331. p21 1 item
  332. DNA Ligases 1 item
  333. Prostaglandin synthesis 1 item
  334. Protein Tyrosine Phosphatases 1 item
  335. alkaline phosphatases 1 item
  336. ATPases 1 item
  337. glutamate release 1 item
  338. PAFR 1 item
  339. Aromatases 2item
  340. DHFR 1 item
  341. GARFT 1 item
  342. PHF 1 item
  343. FGR 1 item
  344. YES 2item
  345. Fyn 2item
  346. ARG 1 item
  347. Autotaxin 1 item
  348. UCH 1 item
  349. RHA 1 item
  350. HCV NS3-4A protease 1 item
  351. PKD 1 item
  352. Thioredoxin Reductases 1 item
  353. enoyl-acyl-carrier protein reductase 1 item
  354. SHIP 1 item
  355. FKBP 1 item
  356. MCL1 1 item
  357. Bcl-w 1 item
  358. glutathione peroxidase 4 1 item
  359. NADH oxidase 1 item
  360. S-adenosylhomocysteine hydrolase 1 item
  361. Rho-kinase 1 item
  362. tropomyosin receptor kinase 1 item
  363. LSD 1 item
  364. DDX3 1 item
  365. PRMT 1 item
  366. ACE 1 item
  367. GLP 1 item
  368. SK 1 item
  369. MST 1 item
  370. PPK 1 item
  371. c-Syk 1 item
  372. CDK1/CyclinB 1 item
  373. NHE 1 item
  374. IDO 1 item
  375. Tph 1 item
  376. PIM1 kinase 1 item
  377. phospholipase A2 1 item
  378. reverse transcriptase 1 item
  379. epoxide hydrolase 1 item
  380. Serotonin (5-HT) reuptake 1 item
  381. Cholesterol absorption 1 item
  382. Vascular Disrupting Agents (VDA) 1 item
  383. Androgen Receptor 1 item
  384. Substance P/NK1 Receptor 1 item
  385. gp120/CD4 1 item
  386. ATM 1 item
  387. Sirtuin 1 item
  388. NE 1 item
  389. PIKfyve 1 item
  390. Bax 1 item
  391. Glycogen Phosphorylases 1 item
  392. MTH1 1 item
  393. PTEN 1 item
  394. Insulin Receptor 1 item
  395. NS3/4a Proteases 1 item
  396. p90 S6K 1 item
Related Disease
  1. Acne 1 item
  2. Acute Kidney Injury 2item
  3. Acute Lung Injury 1 item
  4. Acute Myelogenous Leukemia 4item
  5. Acute Myeloid Leukemia 18item
  6. Acute Renal Failure 1 item
  7. Adrenocortical Carcinoma 3item
  8. Anesthesia 1 item
  9. Biliary Cancer 1 item
  10. Bladder Cancer 9item
  11. Bladder Carcinoma 3item
  12. Bladder Diseases 2item
  13. B-lymphoid Malignancies 1 item
  14. Brain Injuries Studies 3item
  15. Breast Cancer 70item
  16. Cancer 343item
  17. Castration-resistant Prostate Cancer 1 item
  18. Cervical Cancer 4item
  19. Cholangiocarcinoma 1 item
  20. Chronic Lymphocytic Leukemia 6item
  21. Chronic Myeloproliferative Disorders 1 item
  22. Clear Cell Renal Cell Carcinoma 1 item
  23. Cocaine-Related Disorders 2item
  24. Colon Cancer 22item
  25. Colon Carcinoma 3item
  26. Colorectal Cancer 28item
  27. Depression 2item
  28. Diabetes 7item
  29. Diffuse Large B-cell Lymphoma 1 item
  30. Dyskinesia 1 item
  31. Dyslipidemia 2item
  32. Epilepsy 3item
  33. Erectile Dysfunction 3item
  34. Friedreich's Ataxia 1 item
  35. Fungi 1 item
  36. Glioblastoma 18item
  37. Glioma 10item
  38. HCV 3item
  39. Heart Failure 3item
  40. Hepatitis C 3item
  41. Hepatocellular Carcinoma 4item
  42. HIV 11item
  43. HIV Infections 9item
  44. Hypercholesterolemia 1 item
  45. Inflammation 1 item
  46. Inflammatory Diseases 4item
  47. Influenza 1 item
  48. Kidney Injury Studies 2item
  49. Leukemia 16item
  50. Liver Cancer 3item
  51. Lung Cancer 19item
  52. Lung Carcinoma 2item
  53. Lymphoma 22item
  54. Mantle Cell Lymphoma 2item
  55. Melanoma 18item
  56. Mixed Lineage Leukemia 1 item
  57. Multiple Myeloma 15item
  58. Myelofibrosis 2item
  59. Myeloma 2item
  60. Neuroblastoma 6item
  61. Neurocognitive Disorders 1 item
  62. Neuronal Protection 1 item
  63. Non-small Cell Lung Cancer 15item
  64. Non-small Cell Lung Carcinoma 1 item
  65. Obsessive-Compulsive Disorder 1 item
  66. Osteoporosis 2item
  67. Ovarian Cancer 21item
  68. Pancreatic Cancer 31item
  69. Pancreatic Carcinoma 1 item
  70. Prostate Cancer 35item
  71. Psoriasis 3item
  72. Psoriasis Vulgaris 1 item
  73. Pulmonary Fibrosis 2item
  74. Renal Cancer 3item
  75. Renal Cell Carcinoma 4item
  76. Rheumatoid Arthritis 11item
  77. Sarcoma 1 item
  78. Schizophrenia 4item
  79. Sleep Disorders 1 item
  80. Soft Tissue Sarcoma 1 item
  81. Squamous Cell Carcinoma 2item
  82. Thyroid Cancer 4item
  83. Tuberculosis 1 item
  84. Type 2 Diabetes 7item