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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Items 101-110 of 172

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  1. Rucaparib (AG-014699,PF-01367338)
    A4156 Rucaparib (AG-014699,PF-01367338)
    Summary: Potent PARP inhibitor
      ≥21.08 mg/mL
  2. Ellagic acid
    A2306 Ellagic acid
    Summary: Casein kinase 2 (CK2) inhibitor
      insoluble in H2O; insoluble in EtOH; ≥3.78 mg/mL
  3. Romidepsin (FK228, depsipeptide)
    A8173 Romidepsin (FK228, depsipeptide)
     7 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC1/HDAC2 inhibitor, potent and selective
      ≥27.04 mg/mL
  4. AZ20
    A3210 AZ20
     1 Citation
    Target: ATM/ATR
    Summary: ATR inhibitor,potent and selective
      ≥20.65 mg/mL
  5. Fludarabine Phosphate (Fludara)
    A8317 Fludarabine Phosphate (Fludara)
     2 Citation
    Target: STAT
    Summary: Inhibits STAT1 activation and DNA synthesis
      insoluble in EtOH; ≥17.6 mg/mL
  6. LAQ824 (NVP-LAQ824,Dacinostat)
    A4103 LAQ824 (NVP-LAQ824,Dacinostat)
     1 Citation
    Summary: HDAC inhibitor,potent and novel
      insoluble in H2O; insoluble in EtOH; ≥17.45 mg/mL
  7. BYK 204165
    A4525 BYK 204165
    Summary: PARP-1 inhibitor,potent and selective
      <25.23 mg/mL
  8. 4-HQN
    A4524 4-HQN
    Summary: PARP inhibitor
      ≥7.4 mg/mL
  9. BYK 49187
    A4526 BYK 49187
    Summary: Potent PARP-1/PARP-2 inhibitor
      <16.77 mg/mL
  10. Resminostat (RAS2410)
    A4108 Resminostat (RAS2410)
     1 Citation
    Summary: Potent HDAC inhibitor
      Soluble in DMSO

Items 101-110 of 172

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  1. Category DNA Damage/DNA Repair Remove This Item
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Category
  1. MTH1 4item
  2. PARP 32item
  3. ATM/ATR 10item
  4. DNA Alkylating 1 item
  5. DNA Ligases 3item
  6. DNA Methyltransferase 1 item
  7. DNA-PK 8item
  8. DNA Synthesis 26item
  9. HDAC 52item
  10. Nucleoside Antimetabolite/Analogue 4item
  11. Telomerase 3item
  12. Topoisomerase 25item
  13. tankyrase 5item
Specificity
  1. Selective 59item
Reversibility
  1. Reversible 4item
Target
  1. Histone Deacetylases (HDACs) 33item
  2. PI3K 5item
  3. mTOR 1 item
  4. Thymidylate Synthase 2item
  5. STAT 1 item
  6. EGFR 1 item
  7. Tankyrases 1 item
  8. DNA-PK 4item
  9. TNKS 1 item
  10. Topoisomerases 9item
  11. ErbB 1 item
  12. PARP 7item
  13. ATM/ATR 6item
  14. AP endonucleases 1 item
  15. HSV 1 item
  16. FoxM1 1 item
  17. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  18. HDAC 1 item
  19. KDM 1 item
  20. HCV polymerase 1 item
  21. telomerase 1 item
  22. Ribonucleotide Reductases 1 item
  23. Adenosine Deaminases 1 item
  24. DNA Ligases 1 item
  25. PHF 1 item
  26. ATM 2item
  27. MTH1 1 item
Reported Experiments
  1. Animal Experiments 70item
  2. Cell Experiments 61item
Related Disease
  1. Acute Myelogenous Leukemia 2item
  2. Acute Myeloid Leukemia 1 item
  3. Bladder Cancer 3item
  4. Breast Cancer 17item
  5. Cancer 54item
  6. Chronic Lymphocytic Leukemia 1 item
  7. Colon Cancer 9item
  8. Colon Carcinoma 1 item
  9. Colorectal Cancer 6item
  10. Dyskinesia 1 item
  11. Epilepsy 1 item
  12. Friedreich's Ataxia 1 item
  13. Glioma 2item
  14. HCV 1 item
  15. Hepatic Cancer 1 item
  16. Hepatocellular Carcinoma 3item
  17. HIV Infections 1 item
  18. Inflammatory Diseases 1 item
  19. Leukemia 4item
  20. Liver Cancer 1 item
  21. Lung Cancer 5item
  22. Lymphoma 5item
  23. Melanoma 2item
  24. Multiple Myeloma 3item
  25. Myeloma 2item
  26. Neuroblastoma 2item
  27. Neuronal Protection 1 item
  28. Non-small Cell Lung Cancer 3item
  29. Ovarian Cancer 6item
  30. Pancreatic Cancer 3item
  31. Prostate Cancer 8item
  32. Renal Cancer 1 item
  33. Renal Cell Carcinoma 2item
  34. Testicular Cancer 1 item