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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Items 61-70 of 172

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  1. UPF 1069
    A4163 UPF 1069
    Target: PARP
    Summary: Selective PARP2 inhibitor
      insoluble in H2O; ≥12.7 mg/mL
  2. Vorinostat (SAHA, MK0683)
    A4084 Vorinostat (SAHA, MK0683)
     9 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor
      insoluble in EtOH; insoluble in H2O; ≥4.41 mg/mL
  3. Tubacin
    A4501 Tubacin
     3 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC6 inhibitor,potent,selective,reversible,cell-permeable
      insoluble in EtOH; insoluble in H2O; ≥7.19 mg/mL
  4. SCR7
    A8705 SCR7
     6 Citation
    Summary: DNA ligase IV inhibitor
      insoluble in H2O; ≥16.72 mg/mL
  5. BIBR 1532
    A1945 BIBR 1532
     2 Citation
    Target: telomerase
    Summary: Telomerase inhibitor,novel and selective
      insoluble in H2O; ≥15.65 mg/mL
  6. CRT0044876
    B3061 CRT0044876
    Target: AP endonucleases
    Summary: APE1 inhibitor, potent and selective
      ≥55.56 mg/mL
  7. A-966492
    A4160 A-966492
    Target: PARP
    Summary: PARP-1/-2 inhibitor, highly potent
      ≥32.4 mg/mL
  8. Mercaptopurine (6-MP)
    A2355 Mercaptopurine (6-MP)
    Summary: Purine synthesis inhibitor
      insoluble in EtOH; insoluble in H2O; ≥7.61 mg/mL
  9. Amsacrine
    B1302 Amsacrine
    Summary: Topoisomerase 2 inhibitor
      Soluble in DMSO
  10. Rocilinostat (ACY-1215)
    A4083 Rocilinostat (ACY-1215)
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: Selective HDAC6 inhibitor
      ≥21.675 mg/mL

Items 61-70 of 172

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  1. Category DNA Damage/DNA Repair Remove This Item
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Category
  1. MTH1 4item
  2. PARP 32item
  3. ATM/ATR 10item
  4. DNA Alkylating 1 item
  5. DNA Ligases 3item
  6. DNA Methyltransferase 1 item
  7. DNA-PK 8item
  8. DNA Synthesis 26item
  9. HDAC 52item
  10. Nucleoside Antimetabolite/Analogue 4item
  11. Telomerase 3item
  12. Topoisomerase 25item
  13. tankyrase 5item
Specificity
  1. Selective 59item
Reversibility
  1. Reversible 4item
Target
  1. Histone Deacetylases (HDACs) 33item
  2. PI3K 5item
  3. mTOR 1 item
  4. Thymidylate Synthase 2item
  5. STAT 1 item
  6. EGFR 1 item
  7. Tankyrases 1 item
  8. DNA-PK 4item
  9. TNKS 1 item
  10. Topoisomerases 9item
  11. ErbB 1 item
  12. PARP 7item
  13. ATM/ATR 6item
  14. AP endonucleases 1 item
  15. HSV 1 item
  16. FoxM1 1 item
  17. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  18. HDAC 1 item
  19. KDM 1 item
  20. HCV polymerase 1 item
  21. telomerase 1 item
  22. Ribonucleotide Reductases 1 item
  23. Adenosine Deaminases 1 item
  24. DNA Ligases 1 item
  25. PHF 1 item
  26. ATM 2item
  27. MTH1 1 item
Reported Experiments
  1. Animal Experiments 70item
  2. Cell Experiments 61item
Related Disease
  1. Acute Myelogenous Leukemia 2item
  2. Acute Myeloid Leukemia 1 item
  3. Bladder Cancer 3item
  4. Breast Cancer 17item
  5. Cancer 54item
  6. Chronic Lymphocytic Leukemia 1 item
  7. Colon Cancer 9item
  8. Colon Carcinoma 1 item
  9. Colorectal Cancer 6item
  10. Dyskinesia 1 item
  11. Epilepsy 1 item
  12. Friedreich's Ataxia 1 item
  13. Glioma 2item
  14. HCV 1 item
  15. Hepatic Cancer 1 item
  16. Hepatocellular Carcinoma 3item
  17. HIV Infections 1 item
  18. Inflammatory Diseases 1 item
  19. Leukemia 4item
  20. Liver Cancer 1 item
  21. Lung Cancer 5item
  22. Lymphoma 5item
  23. Melanoma 2item
  24. Multiple Myeloma 3item
  25. Myeloma 2item
  26. Neuroblastoma 2item
  27. Neuronal Protection 1 item
  28. Non-small Cell Lung Cancer 3item
  29. Ovarian Cancer 6item
  30. Pancreatic Cancer 3item
  31. Prostate Cancer 8item
  32. Renal Cancer 1 item
  33. Renal Cell Carcinoma 2item
  34. Testicular Cancer 1 item