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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Items 91-100 of 177

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  1. LY2584702
    B5815 LY2584702
    Target: p70 rsk
    Summary: p70 S6 kinase inhibitor
      ≥22.25 mg/mL
  2. Tideglusib
    B1539 Tideglusib
     1 Citation
    Summary: non-ATP-competitive GSK-3β inhibitor
      insoluble in EtOH; insoluble in H2O; ≥16.7 mg/mL
  3. WYE-354
    A1266 WYE-354
    Summary: MTOR inhibitor,potent,ATP-competitive and cell-permeable
      ≥49.6 mg/mL
  4. PHT-427
    A5884 PHT-427
    Summary: Akt and PDPK1 inhibitor
      insoluble in H2O; ≥20.5 mg/mL
  5. GNE-477
    B8001 GNE-477
    Summary: dual PI3K/mTOR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥16.69 mg/mL
  6. OSU-03012 (AR-12)
    A2846 OSU-03012 (AR-12)
     1 Citation
    Target: PDK-1
    Summary: Potent PDK1 inhibitor
      ≥23 mg/mL
  7. ETP-46464
    A8626 ETP-46464
    Target: PI3K|mTOR|DNA-PK|ATM/ATR
    Summary: ATR inhibitor,potent and selective
      ≥16.13 mg/mL
  8. Acalisib (GS-9820)
    B5831 Acalisib (GS-9820)
    Target: PI3K
    Summary: PI3Kδ inhibitor
      insoluble in H2O; insoluble in EtOH; ≥19.2 mg/mL
  9. PIK-294
    B2188 PIK-294
    Summary: highly selective p110δ inhibitor
      ≥24.5 mg/mL
  10. AS-252424
    B2180 AS-252424
    Target: Akt|PI3K
    Summary: PI3Kγ inhibitor,novel and potent
      insoluble in EtOH; insoluble in H2O; ≥30.5 mg/mL

Items 91-100 of 177

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  1. Category PI3K/Akt/mTOR Signaling Remove This Item
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Category
  1. Akt 26item
  2. AMPK 8item
  3. CK2 8item
  4. DNA-PK 5item
  5. eNOS 2item
  6. GSK-3 17item
  7. MELK 2item
  8. mTOR 29item
  9. PI3K 61item
  10. PI4K 1 item
  11. PDK-1 8item
  12. PIKfyve 1 item
  13. PKB 1 item
  14. S6 Kinase 9item
Specificity
  1. Selective 61item
Reversibility
  1. Reversible 4item
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 2item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 13item
  4. PI3K 35item
  5. mTOR 22item
  6. GSK-3 10item
  7. Eph Receptors 1 item
  8. VEGFR 1 item
  9. PDGFR 1 item
  10. Bcr-Abl 1 item
  11. Pim 1 item
  12. Ribosomal s6 kinases (RSK) 1 item
  13. Src 1 item
  14. DNA-PK 8item
  15. AMPK 2item
  16. S6 kinases 1 item
  17. ERK 1 item
  18. PKC 2item
  19. PKG 1 item
  20. PKA 3item
  21. MELK 1 item
  22. NUAK1 1 item
  23. NUAK2 1 item
  24. RSK 1 item
  25. ATM/ATR 2item
  26. CK2 3item
  27. HIPK2 1 item
  28. HIPK3 1 item
  29. P110 1 item
  30. Hck 1 item
  31. p70 rsk 3item
  32. PDK-1 1 item
  33. Prk 1 item
  34. NUAK 1 item
  35. NOS 1 item
  36. PIM1 kinase 1 item
  37. phospholipase A2 1 item
  38. ATM 1 item
  39. PIKfyve 1 item
  40. p90 S6K 1 item
Reported Experiments
  1. Animal Experiments 79item
  2. Cell Experiments 60item
Related Disease
  1. Adrenocortical Carcinoma 1 item
  2. Bladder Cancer 1 item
  3. Bladder Carcinoma 1 item
  4. Breast Cancer 14item
  5. Cancer 50item
  6. Cervical Cancer 1 item
  7. Cholangiocarcinoma 1 item
  8. Chronic Lymphocytic Leukemia 1 item
  9. Colon Cancer 3item
  10. Colon Carcinoma 1 item
  11. Colorectal Cancer 2item
  12. Diabetes 1 item
  13. Glioblastoma 5item
  14. Glioma 5item
  15. Hepatocellular Carcinoma 1 item
  16. Leukemia 1 item
  17. Lung Cancer 6item
  18. Melanoma 2item
  19. Neuroblastoma 2item
  20. Non-small Cell Lung Cancer 1 item
  21. Ovarian Cancer 4item
  22. Pancreatic Cancer 6item
  23. Prostate Cancer 5item
  24. Renal Cancer 1 item
  25. Rheumatoid Arthritis 1 item
  26. Type 2 Diabetes 1 item