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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Items 41-50 of 219

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  1. LY2603618
    A8638 LY2603618
     3 Citation
    Summary: Chk1 inhibitor,highly selective
      ≥43.6 mg/mL
  2. MLN0905
    A8680 MLN0905
    Target: PLK
    Summary: Potent PLK1 inhibitor
      ≥24.35 mg/mL
  3. LEE011
    A8641 LEE011
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥10.88 mg/mL
  4. ARRY 520 trifluoroacetate
    A4458 ARRY 520 trifluoroacetate
    Summary: KSP inhibitor
      Soluble in DMSO
  5. ML167
    B3707 ML167
    Target: Clk
    Summary: Clk4 inhibitor,highly selective
      insoluble in EtOH; insoluble in H2O; ≥16.75 mg/mL
  6. VE-822
    B1383 VE-822
     2 Citation
    Target: ATM/ATR
    Summary: ATR inhibitor
      ≥50 mg/mL
  7. THZ1 Hydrochloride
    B4736 THZ1 Hydrochloride
    Target: Cyclin-Dependent Kinases
    Summary: CDK7 inhibitor
      ≥30.13 mg/mL
  8. AMG 925
    B3277 AMG 925
    Target: Cyclin-Dependent Kinases|FLT3
    Summary: FLT3/CDK4 inhibitor,potent and selective
      insoluble in DMSO; insoluble in H2O; insoluble in EtOH
  9. ISRIB (trans-isomer)
    B3699 ISRIB (trans-isomer)
    Summary: PERK inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; insoluble in EtOH; ≥8.96 mg/mL
  10. LY2606368
    B1088 LY2606368
    Target: Chk
    Summary: CHK1 inhibitor
      insoluble in DMSO

Items 41-50 of 219

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Category
  1. ATM/ATR 9item
  2. Aurora Kinase 28item
  3. Cdc42 4item
  4. Cdc7 2item
  5. Chk 15item
  6. c-Myc 3item
  7. CRM1 4item
  8. Cyclin-Dependent Kinases 63item
  9. E1 enzyme 1 item
  10. G-quadruplex 2item
  11. Haspin 1 item
  12. HMTase 1 item
  13. Kinesin 7item
  14. Ksp 4item
  15. Microtubule/Tubulin 14item
  16. Mps1 3item
  17. Mitotic 1 item
  18. RAD51 2item
  19. ROCK 15item
  20. Rho 12item
  21. PAK1 4item
  22. PAK4 2item
  23. PERK 4item
  24. PLK 17item
  25. PTEN 2item
  26. Wee1 1 item
Specificity
  1. Selective 75item
Reversibility
  1. Reversible 9item
  2. Irreversible 2item
Target
  1. Cyclin-Dependent Kinases 30item
  2. PI3K 2item
  3. Aurora Kinases 20item
  4. mTOR 1 item
  5. FLT3 5item
  6. GSK-3 1 item
  7. PLK 11item
  8. Chk 8item
  9. VEGFR 1 item
  10. PDGFR 1 item
  11. RET 1 item
  12. Bromodomain-containing proteins(BRDs) 1 item
  13. MEK 1 item
  14. FGFR 1 item
  15. Src 3item
  16. Microtubules/Tubulins 2item
  17. ROCK 10item
  18. PAK 3item
  19. JAK 1 item
  20. DNA-PK 1 item
  21. Ksp 2item
  22. PKC 1 item
  23. RAD51 2item
  24. LRRK2 1 item
  25. KRAS G12C 1 item
  26. PKG 1 item
  27. PKA 1 item
  28. Myosin light chain kinases (MLCKs) 1 item
  29. Clk 1 item
  30. MK2 1 item
  31. ATM/ATR 6item
  32. Farnesyl Diphosphate Synthases 1 item
  33. Cdc42 1 item
  34. Hck 1 item
  35. Arp2/3 complex 1 item
  36. Cdc7 1 item
  37. Ubiquitin-activating Enzyme E1 1 item
  38. Microtubule/Tubulin 1 item
  39. VEGFR3/FLT4 1 item
  40. NTRK1/TRKA 1 item
  41. CSF-1R/c-Fms 1 item
  42. nuclear export 1 item
  43. CRM1 1 item
  44. Hec1 1 item
  45. Histone Acetyltransferases (HATs) 1 item
  46. Rho 1 item
  47. Lck 1 item
  48. FGR 1 item
  49. YES 1 item
  50. Fyn 1 item
  51. ARG 1 item
  52. Rho-kinase 1 item
  53. ATM 1 item
  54. PTEN 1 item
Reported Experiments
  1. Animal Experiments 84item
  2. Cell Experiments 69item
Related Disease
  1. Acute Myeloid Leukemia 7item
  2. B-lymphoid Malignancies 1 item
  3. Breast Cancer 14item
  4. Cancer 71item
  5. Cervical Cancer 1 item
  6. Chronic Lymphocytic Leukemia 2item
  7. Colon Cancer 10item
  8. Colon Carcinoma 1 item
  9. Colorectal Cancer 5item
  10. Glioblastoma 2item
  11. Glioma 2item
  12. Leukemia 1 item
  13. Liver Cancer 1 item
  14. Lung Cancer 6item
  15. Lymphoma 3item
  16. Mantle Cell Lymphoma 1 item
  17. Melanoma 2item
  18. Multiple Myeloma 1 item
  19. Neuroblastoma 1 item
  20. Non-small Cell Lung Carcinoma 1 item
  21. Ovarian Cancer 7item
  22. Pancreatic Cancer 7item
  23. Prostate Cancer 5item
  24. Renal Cell Carcinoma 1 item
  25. Thyroid Cancer 1 item