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Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

A8316 PD 0332991 (Palbociclib) HCl

5 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK4/6 inhibitor,highly selective

≥14.48 mg/mL
B4754 LDC000067

2 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK9 inhibitor, novel and highly specific

insoluble in H2O; insoluble in EtOH; ≥18.52 mg/mL
A8385 BMS265246

Target: Cyclin-Dependent Kinases

Summary: CDK1/2 inhibitor,potent and selective

insoluble in H2O; insoluble in EtOH; ≥17.25 mg/mL
A3336 CVT-313

1 Citation

Target: Cyclin-Dependent Kinases

Summary: Cdk2 inhibitor

≥20 mg/mL
A8477 MK-8776 (SCH-900776)

Target: Chk

Summary: Chk1 inhibitor,potent and selective

insoluble in H2O; insoluble in EtOH; ≥18.8 mg/mL
A1352 Zoledronic Acid

Target: Farnesyl Diphosphate Synthases

Summary: Potent nitrogen-containing bisphosphonates

insoluble in DMSO; insoluble in H2O; insoluble in EtOH
B1236 BML-277

Target: Chk

Summary: Chk2 inhibitor,potent and highly selective

insoluble in H2O; ≥18.2 mg/mL
B1162 FRAX597

1 Citation

Target: PAK

Summary: PAK inhibitor,potent and ATP-competitive

≥27.9 mg/mL
A8412 Dinaciclib (SCH727965)

2 Citation

Target: Cyclin-Dependent Kinases

Summary: Potent CDK inhibitor
B4094 NMS-1286937

Target: PLK

Summary: PLK1 inhibitor, orally bioavailable

insoluble in H2O; insoluble in EtOH; ≥13.33 mg/mL