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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Items 51-60 of 69

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  1. VX-680 (MK-0457,Tozasertib)
    A4111 VX-680 (MK-0457,Tozasertib)
    Target: Aurora Kinases
    Summary: Aurora kinase inhibitor
      ≥23.25 mg/mL
  2. CYC116
    A4125 CYC116
    Target: Aurora Kinases|FLT3|VEGFR
    Summary: Potent Aurora A/B inhibitor
      insoluble in EtOH; insoluble in H2O; ≥18.4 mg/mL
  3. KPT-276
    B1463 KPT-276
    Target: nuclear export|CRM1
    Summary: inhibitor of nuclear export (SINE) and CRM1, orally bioavailable
      insoluble in EtOH; insoluble in H2O; ≥19.85 mg/mL
  4. AZD1152
    A3214 AZD1152
     1 Citation
    Target: Aurora Kinases
    Summary: Aurora B kinase inhibitor,highly potent and selective
      insoluble in H2O; insoluble in EtOH; ≥5.88 mg/mL
  5. JNJ-7706621
    A4115 JNJ-7706621
     1 Citation
    Target: Cyclin-Dependent Kinases|Aurora Kinases
    Summary: Potent CDK/Aurora kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥19.7 mg/mL
  6. PHA-680632
    A4122 PHA-680632
    Target: Aurora Kinases|PLK|FGFR
    Summary: Aurora kinase inhibitor,novel and potent
      ≥50.2 mg/mL
  7. SNS-314 Mesylate
    A4121 SNS-314 Mesylate
    Target: Aurora Kinases
    Summary: Aurora A/B/C kinases inhibitor, potent and selective
      ≥26.35 mg/mL
  8. GSK461364
    A8441 GSK461364
     3 Citation
    Target: PLK
    Summary: Plk1 inhibitor
  9. Fasudil
    B3523 Fasudil
    Target: ROCK|PKC|PKG|PKA|Myosin light chain kinases (MLCKs)
    Summary: calcium antagonist
      Soluble in DMSO
  10. ENMD-2076
    A4130 ENMD-2076
    Target: Aurora Kinases|FLT3|RET|Src|VEGFR3/FLT4|NTRK1/TRKA|CSF-1R/c-Fms
    Summary: Selective Aurora A/Flt3 inhibitor
      insoluble in H2O; ≥18.75 mg/mL

Items 51-60 of 69

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Category
  1. ATM/ATR 4item
  2. Aurora Kinase 17item
  3. Cdc42 1 item
  4. Cdc7 1 item
  5. Chk 4item
  6. CRM1 1 item
  7. Cyclin-Dependent Kinases 18item
  8. E1 enzyme 1 item
  9. Ksp 1 item
  10. Microtubule/Tubulin 3item
  11. RAD51 1 item
  12. ROCK 5item
  13. Rho 3item
  14. PERK 1 item
  15. PLK 8item
  16. PTEN 1 item
Specificity
  1. Selective 39item
Reversibility
  1. Reversible 4item
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 20item
  2. PI3K 1 item
  3. Aurora Kinases 16item
  4. mTOR 1 item
  5. FLT3 5item
  6. GSK-3 1 item
  7. PLK 9item
  8. Chk 4item
  9. VEGFR 1 item
  10. PDGFR 1 item
  11. RET 1 item
  12. Bromodomain-containing proteins(BRDs) 1 item
  13. MEK 1 item
  14. FGFR 1 item
  15. Src 3item
  16. Microtubules/Tubulins 1 item
  17. ROCK 5item
  18. JAK 1 item
  19. DNA-PK 1 item
  20. Ksp 1 item
  21. PKC 1 item
  22. RAD51 1 item
  23. LRRK2 1 item
  24. PKG 1 item
  25. PKA 1 item
  26. Myosin light chain kinases (MLCKs) 1 item
  27. MK2 1 item
  28. ATM/ATR 4item
  29. Farnesyl Diphosphate Synthases 1 item
  30. Cdc42 1 item
  31. Hck 1 item
  32. Cdc7 1 item
  33. Ubiquitin-activating Enzyme E1 1 item
  34. Microtubule/Tubulin 1 item
  35. VEGFR3/FLT4 1 item
  36. NTRK1/TRKA 1 item
  37. CSF-1R/c-Fms 1 item
  38. nuclear export 1 item
  39. CRM1 1 item
  40. Hec1 1 item
  41. Histone Acetyltransferases (HATs) 1 item
  42. Rho 1 item
  43. Lck 1 item
  44. FGR 1 item
  45. YES 1 item
  46. Fyn 1 item
  47. ARG 1 item
  48. Rho-kinase 1 item
  49. PTEN 1 item
Related Disease
  1. Acute Myeloid Leukemia 3item
  2. B-lymphoid Malignancies 1 item
  3. Breast Cancer 4item
  4. Cancer 46item
  5. Cervical Cancer 1 item
  6. Chronic Lymphocytic Leukemia 2item
  7. Colon Cancer 3item
  8. Colon Carcinoma 1 item
  9. Colorectal Cancer 3item
  10. Glioma 2item
  11. Leukemia 1 item
  12. Lung Cancer 2item
  13. Lymphoma 2item
  14. Mantle Cell Lymphoma 1 item
  15. Melanoma 1 item
  16. Multiple Myeloma 1 item
  17. Ovarian Cancer 3item
  18. Pancreatic Cancer 4item
  19. Prostate Cancer 2item
  20. Renal Cell Carcinoma 1 item
  21. Thyroid Cancer 1 item