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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Items 101-110 of 981

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  1. IPI-504 (Retaspimycin hydrochloride)
    A4061 IPI-504 (Retaspimycin hydrochloride)
     3 Citation
    Target: HSP90
    Summary: Hsp90 inhibitor,novel, potent,selective
      ≥26.1 mg/mL
  2. PHA-848125
    A8501 PHA-848125
    Target: Cyclin-Dependent Kinases
    Summary: CDK inhibitor,potent and ATP-competitive
      ≥23.05 mg/mL
  3. PF-3644022
    B5549 PF-3644022
    Target: MK2
    Summary: Potent and Selective MK2 inhibitor
      <14.98 mg/mL
  4. OTX-015
    A3692 OTX-015
     3 Citation
    Target: Bromodomains
    Summary: BRD inhibitor
      ≥24.6 mg/mL
  5. Cercosporamide
    A4511 Cercosporamide
    Target: JAK|MNK
    Summary: Mnk2 and JAK3 inhibitor
      soluble in DMSO
  6. ICG 001
    A8217 ICG 001
     1 Citation
    Summary: Wnt/β-catenin pathway inhibitor
      ≥27.43 mg/mL
  7. SRPIN340
    B2032 SRPIN340
    Target: SRPK1
    Summary: Selective SRPK1 inhibitor
      insoluble in H2O; ≥10.9 mg/mL
  8. ZIP (SCRAMBLED)
    A8830 ZIP (SCRAMBLED)
    Summary: PKMζ inhibitor
      ≥192.8 mg/mL
  9. PFI-1 (PF-6405761)
    A4184 PFI-1 (PF-6405761)
     1 Citation
    Target: Bromodomains
    Summary: BET inhibitor
      insoluble in H2O; insoluble in EtOH; ≥128.4 mg/mL
  10. GSK2606414
    A3448 GSK2606414
     4 Citation
    Summary: PERK inhibitor,potent and selective
      ≥22.57 mg/mL

Items 101-110 of 981

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  1. Signaling Pathways 942item
  2. Natural Products 8item
  3. Peptides 1 item
  4. Probes & Dyes 1 item
  5. Peptides & Proteins 2item
  6. Lab Reagents 4item
Specificity
  1. Selective 695item
  2. Non-Selective 5item
Reversibility
  1. Reversible 54item
  2. Irreversible 31item
Target
  1. Caspases 8item
  2. Cyclin-Dependent Kinases 25item
  3. Proteasome 12item
  4. Cathepsins 9item
  5. Histone Deacetylases (HDACs) 32item
  6. Inhibitor of apoptosis proteins (IAP) 2item
  7. Akt 13item
  8. Bcl-2 8item
  9. PI3K 36item
  10. CXCR 4item
  11. Raf 13item
  12. Aurora Kinases 20item
  13. Bcl-xl 2item
  14. CSF-1R 4item
  15. Glycoproteins 1 item
  16. p97 1 item
  17. Gap Junctions 1 item
  18. MDM2 2item
  19. EZH2 4item
  20. mTOR 20item
  21. Bromodomains 6item
  22. AP-1 1 item
  23. MMP 7item
  24. Thymidine Phosphorylases 1 item
  25. Androgen Receptors 4item
  26. Peptidylprolyl isomerases 1 item
  27. Acyl coenzyme A: cholesterol acyltransferases 1 item
  28. Myosin II ATPases 1 item
  29. DT-diaphorases 1 item
  30. Voltage-gated Potassium (KV) Channels 1 item
  31. MER 1 item
  32. FLT3 19item
  33. GSK-3 10item
  34. Factor Xa 4item
  35. P-glycoprotein (P-gp) 5item
  36. PLK 10item
  37. Chk 7item
  38. Eph Receptors 2item
  39. VEGFR 40item
  40. PDGFR 25item
  41. c-Kit 13item
  42. RET 4item
  43. IRAK 1 item
  44. Bromodomain-containing proteins(BRDs) 1 item
  45. Phosphodiesterases (PDEs) 16item
  46. Mcl-1 6item
  47. Hydrolase 1 item
  48. Thymidylate Synthase 3item
  49. p38 9item
  50. PKB 1 item
  51. JNK 3item
  52. SGK 1 item
  53. Bcr-Abl 13item
  54. Kynurenine-3-monooxygenase 1 item
  55. MEK 13item
  56. PORCN 1 item
  57. DOT1L 3item
  58. FGFR 17item
  59. Nrf2 2item
  60. Insulin-like growth factor receptors(IGFRs) 1 item
  61. Pim 4item
  62. Liver X receptors (LXRs) 1 item
  63. Sir2-like Family Deacetylases (Sirtuins) 3item
  64. Voltage-gated Sodium (NaV) Channels 1 item
  65. Deubiquitinating enzymes (DUBs) 3item
  66. PP1 1 item
  67. PP2A 1 item
  68. Smoothened 4item
  69. Neuraminidases (NA) 2item
  70. MET 7item
  71. Src 14item
  72. Trk Receptors 6item
  73. Integrins 1 item
  74. Aminopeptidases 3item
  75. NMDA Receptors 1 item
  76. STAT 11item
  77. ATP Citrate Lyases 1 item
  78. Microtubules/Tubulins 4item
  79. Estrogen and Related Receptors 1 item
  80. EGFR 23item
  81. Hedgehog 1 item
  82. Reverse Transcriptases 6item
  83. ROCK 9item
  84. BTK 1 item
  85. RIP kinases 1 item
  86. Monocyte chemotactic proteins 1 item
  87. PAK 3item
  88. Hypoxia Inducible Factors (HIFs) 2item
  89. Tankyrases 1 item
  90. Inositol Phosphatases 1 item
  91. FAK 7item
  92. BMP and Other Activin Receptors 3item
  93. JAK 20item
  94. p300 1 item
  95. Stearoyl-CoA 9-desaturase (SCD-1) 2item
  96. Syk 7item
  97. EZH1 2item
  98. DNA-PK 7item
  99. HSP90 12item
  100. AMPK 2item
  101. Gutathione S-transferase 1 item
  102. PDHK 1 item
  103. Angiotensin AT2 Receptors 1 item
  104. Notch 1 item
  105. S-nitrosoglutathione reductase 1 item
  106. CFTR 4item
  107. TNKS 1 item
  108. Topoisomerases 13item
  109. Cytochrome P450 (CYP450) 8item
  110. thrombin 1 item
  111. Ksp 2item
  112. Renin 1 item
  113. Influenza viruses 1 item
  114. ErbB 5item
  115. S6 kinases 1 item
  116. Toll-like receptors (TLRs) 3item
  117. Adenosine Kinases 2item
  118. Serine Proteases 2item
  119. DNA Methyltransferases 2item
  120. Survivin 1 item
  121. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  122. ERK 8item
  123. HMG-CoA Reductases 6item
  124. c-MET 8item
  125. BMI-1 1 item
  126. PKC 14item
  127. Calpains 5item
  128. Ubiquitin-specific proteases 1 item
  129. HCV Proteases 3item
  130. Ca2 /calmodulin-dependent protein kinases (CaMKs) 6item
  131. MLK3 1 item
  132. O-GlcNAcase 1 item
  133. CREBBP 1 item
  134. EP300 1 item
  135. Lyn 2item
  136. SGLT 1 item
  137. RAD51 2item
  138. Trypsins 1 item
  139. HER2 3item
  140. Pyk2 3item
  141. USP 1 item
  142. 5-HT2 Receptors 4item
  143. LRRK2 6item
  144. Voltage-gated Calcium Channels (CaV) 2item
  145. DGAT 2item
  146. Insulin and Insulin-like Receptors 4item
  147. PARP 7item
  148. CB1 Receptors 1 item
  149. Melanocortin (MC) Receptors 1 item
  150. Pyruvate dehydrogenases (PDH) 2item
  151. ALK 10item
  152. ROS1 2item
  153. Sphingosine kinases (SphKs) 3item
  154. Trypsin 1 item
  155. Chymotrypsin 1 item
  156. Kallikrein 1 item
  157. Trypsinogen 1 item
  158. Monocarboxylate transporters (MCTs) 2item
  159. CETP 2item
  160. Dehydrogenase 1 item
  161. PKG 2item
  162. PKA 6item
  163. Myosin light chain kinases (MLCKs) 2item
  164. HIV-1 gp120 1 item
  165. D1 and D5 Receptors 1 item
  166. D2 Receptors 3item
  167. D3 Receptors 2item
  168. 5-HT1 Receptors 2item
  169. 5-HT7 Receptors 1 item
  170. MELK 1 item
  171. Serotonin reuptake 1 item
  172. Insulin-like growth factors (IGFs) 1 item
  173. CSF1R 1 item
  174. Bromodomain and Extra-Terminal motif (BET) 1 item
  175. Lactate Dehydrogenases (LDH) 2item
  176. MK2 2item
  177. Fatty-acid-binding proteins (FABPs) 1 item
  178. Angiotensin-Converting Enzymes (ACEs) 6item
  179. Tie-2 5item
  180. RSK 3item
  181. p70 S6K 1 item
  182. Free Fatty Acid Receptors 1 item
  183. phosphatases 2item
  184. Autophagy 4item
  185. ATM/ATR 5item
  186. COX 12item
  187. CK1 1 item
  188. Farnesyl Diphosphate Synthases 1 item
  189. CK2 2item
  190. HIPK2 1 item
  191. HIPK3 1 item
  192. HIV Integrases 2item
  193. Squalene epoxidases 2item
  194. PRAK 1 item
  195. MAPKAP-K2 1 item
  196. Delayed rectifier outward potassium current (IKr) 1 item
  197. GpIIb/IIIa receptor 1 item
  198. Guanine nucleotide exchange factors (GEFs) 1 item
  199. 20S proteasomal chymotrypsin 1 item
  200. Geranylgeranyltransferase I 1 item
  201. Farnesyltransferase 1 item
  202. Nampt 3item
  203. eIF4F 1 item
  204. Cdc42 1 item
  205. SRPK1 1 item
  206. P2X Receptors 1 item
  207. Glutaminases 2item
  208. Carbonic Anhydrases 7item
  209. Ron 1 item
  210. G9a 1 item
  211. BLM 1 item
  212. HSV 1 item
  213. NADPH Oxidases 3item
  214. Calcium-activated chloride channels (CaCC) 1 item
  215. GPR35 1 item
  216. Aldehyde Dehydrogenases 1 item
  217. Synthases/Synthetases 2item
  218. MAGL 1 item
  219. Histamine H1 Receptors 2item
  220. Na /K ATPases 3item
  221. P110 1 item
  222. Hck 2item
  223. Inositol-requiring enzyme 1 (IRE1) 2item
  224. Na /K /Cl- Symporters (NKCCs) 2item
  225. GABAA Receptors 2item
  226. Phospholipases 1 item
  227. Monoamine oxidases (MAOs) 1 item
  228. Organic anion transporters (OATs) 1 item
  229. TRP Channel 1 item
  230. RNA Polymerases 2item
  231. Norepinephrine transporter 1 item
  232. 5-HT Transporters 3item
  233. Xanthine oxidoreductases 1 item
  234. Dihydroorotate dehydrogenase 1 item
  235. FoxM1 1 item
  236. Histone Demethylases 1 item
  237. MNK 2item
  238. 5-Lipoxygenases 1 item
  239. NO Donors / Precursors 2item
  240. CB2 Receptors 1 item
  241. HIV-1 reverse transcriptase 1 item
  242. IL Receptors 2item
  243. CCL2 1 item
  244. Noradrenaline reuptake 1 item
  245. Norepinephrine transporters 1 item
  246. Calcium-Activated Potassium (KCa) Channels 2item
  247. AChE 3item
  248. Insulin Receptors 1 item
  249. IRG-1R 1 item
  250. cAMP 1 item
  251. Sulfonylurea receptors 1 item
  252. Cdc2-like kinase (Clk) 1 item
  253. eEF-2 1 item
  254. Inward Rectifier Potassium (Kir) Channels 3item
  255. Cdc7 1 item
  256. CMV 1 item
  257. ZAP-70 1 item
  258. Catechol O-Methyltransferase (COMT) 2item
  259. fibrinolysis 1 item
  260. Angiotensin AT1 Receptors 1 item
  261. D4 Receptors 1 item
  262. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  263. NMDA receptor 1 item
  264. HBV Proteases 1 item
  265. Hydroxylases 2item
  266. Flk-1 1 item
  267. Papains 1 item
  268. Protein Arginine Methyltransferases 1 item
  269. IMPDH 1 item
  270. Na /Ca2 Exchangers (NCXs) 1 item
  271. NAE 2item
  272. Ubiquitin-activating Enzyme E1 2item
  273. SUMOylation 1 item
  274. ATGL 1 item
  275. BACE 1 item
  276. Cytidine deaminases 1 item
  277. GPR40 1 item
  278. angiogenesis 1 item
  279. Glucagon Receptors 1 item
  280. 15-PGDH 1 item
  281. DPP-4 5item
  282. PP4 1 item
  283. c-RET 3item
  284. Nonstructural protein 5B (NS5B) 1 item
  285. p70 rsk 3item
  286. voltage-gated chloride channels 1 item
  287. FPTase 1 item
  288. Microtubule/Tubulin 1 item
  289. VEGFR3/FLT4 1 item
  290. NTRK1/TRKA 1 item
  291. CSF-1R/c-Fms 1 item
  292. Tryptophan hydroxylases (TPH) 2item
  293. ADAMs 1 item
  294. NMPRTase 1 item
  295. Bfl-1 1 item
  296. TAM kinase 1 item
  297. p53-MDM2 interaction 1 item
  298. nuclear export 1 item
  299. CRM1 1 item
  300. PTP 1 item
  301. KDR 2item
  302. Fyn kinase 1 item
  303. Trypsin-like protease 1 item
  304. AXL 1 item
  305. Glyoxalase I 1 item
  306. ERAD 1 item
  307. Dipeptidyl-peptidase II 1 item
  308. p53 6item
  309. metalloprotease 1 item
  310. HDAC 2item
  311. 5-HT receptors 1 item
  312. sodium channel 3item
  313. c-Fms tyrosine kinase 1 item
  314. human lyase 1 item
  315. insulin 1 item
  316. Ub-conjugating enzyme (E2) complex 1 item
  317. Smoothened receptor 1 item
  318. cysteine protease 2item
  319. HDM2 ubiquitin ligase 1 item
  320. IKK 1 item
  321. MSK 1 item
  322. gp120-CD4 interaction 1 item
  323. HCV polymerase 2item
  324. Ftase 1 item
  325. PC-PLC 2item
  326. Elastases 1 item
  327. Glucosidases 1 item
  328. Mer tyrosine kinase 1 item
  329. Hec1 1 item
  330. neprilysin 1 item
  331. GLI 1 item
  332. decarboxylase 1 item
  333. HMGCR 1 item
  334. ErbB-2 1 item
  335. adrenergic receptor 2item
  336. 5-HT4 Receptor 1 item
  337. sterol demethylase 1 item
  338. PDK-1 1 item
  339. GAPDH 1 item
  340. Histone Acetyltransferases (HATs) 2item
  341. complex I of the mitochondrial electron transport chain 1 item
  342. F1 Fo-ATPase 1 item
  343. Prk 1 item
  344. potassium channel 1 item
  345. calcium channel 1 item
  346. Ribonucleotide Reductases 1 item
  347. Trx 1 item
  348. Tyrosinases 1 item
  349. HSP70 1 item
  350. ICAM 1 item
  351. ITK 1 item
  352. HIF-PH 1 item
  353. NUAK 1 item
  354. Rho 1 item
  355. Ubiquitin E3 Ligases 1 item
  356. DCLK2 1 item
  357. FAAH 1 item
  358. PTK 1 item
  359. integrase 1 item
  360. NOS 2item
  361. TYK2 2item
  362. MUSK 1 item
  363. MAP3K 1 item
  364. GPR3 1 item
  365. Adenosine Deaminases 2item
  366. mitochondrial pyruvate carrier (MPC) 1 item
  367. prolactin secretion 1 item
  368. gonadotropin release 1 item
  369. DprE 1 item
  370. carnitine reabsorption 1 item
  371. Histamine receptors 1 item
  372. GluR 1 item
  373. 5-HT receptor 1 item
  374. dopamine receptors 1 item
  375. AMPA receptor 1 item
  376. 5-alpha Reductases 1 item
  377. Flk1 2item
  378. p21 1 item
  379. Prostaglandin synthesis 1 item
  380. Protein Tyrosine Phosphatases 1 item
  381. alkaline phosphatases 1 item
  382. ATPases 1 item
  383. glutamate release 1 item
  384. PAFR 1 item
  385. Aromatases 2item
  386. DHFR 1 item
  387. GARFT 1 item
  388. FGR 1 item
  389. YES 2item
  390. Fyn 2item
  391. ARG 1 item
  392. Autotaxin 1 item
  393. UCH 1 item
  394. RHA 1 item
  395. HCV NS3-4A protease 1 item
  396. PKD 1 item
  397. Pyruvate kinases 1 item
  398. Thioredoxin Reductases 1 item
  399. enoyl-acyl-carrier protein reductase 1 item
  400. SHIP 1 item
  401. FKBP 1 item
  402. MCL1 1 item
  403. Bcl-w 1 item
  404. glutathione peroxidase 4 1 item
  405. S-adenosylhomocysteine hydrolase 1 item
  406. Rho-kinase 1 item
  407. tropomyosin receptor kinase 1 item
  408. LSD 1 item
  409. DDX3 1 item
  410. PRMT 1 item
  411. ACE 1 item
  412. GLP 1 item
  413. SK 1 item
  414. MST 1 item
  415. PPK 1 item
  416. c-Syk 1 item
  417. CDK1/CyclinB 1 item
  418. NHE 1 item
  419. IDO 2item
  420. Tph 1 item
  421. PIM1 kinase 1 item
  422. phospholipase A2 1 item
  423. reverse transcriptase 1 item
  424. epoxide hydrolase 1 item
  425. Serotonin (5-HT) reuptake 1 item
  426. Cholesterol absorption 1 item
  427. Vascular Disrupting Agents (VDA) 1 item
  428. Androgen Receptor 1 item
  429. Substance P/NK1 Receptor 1 item
  430. gp120/CD4 1 item
  431. ATM 1 item
  432. Sirtuin 1 item
  433. NE 1 item
  434. PIKfyve 1 item
  435. Bax 1 item
  436. Glycogen Phosphorylases 1 item
  437. MTH1 1 item
  438. PTEN 1 item
  439. Insulin Receptor 1 item
  440. NS3/4a Proteases 1 item
  441. Ca2 -ATPases 1 item
  442. p90 S6K 1 item
  443. Dynamins 1 item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acne 1 item
  3. Acute Disseminated Candidiasis 1 item
  4. Acute Kidney Injury 2item
  5. Acute Lung Injury 1 item
  6. Acute Myelogenous Leukemia 5item
  7. Acute Myeloid Leukemia 25item
  8. Acute Renal Failure 1 item
  9. Adrenocortical Carcinoma 4item
  10. Advanced Renal Cell Carcinoma 1 item
  11. Anesthesia 1 item
  12. Autoimmune Diseases 1 item
  13. Biliary Cancer 1 item
  14. Bladder Cancer 11item
  15. Bladder Carcinoma 4item
  16. Bladder Diseases 2item
  17. B-lymphoid Malignancies 1 item
  18. Brain Injuries Studies 3item
  19. Breast Cancer 116item
  20. Cancer 509item
  21. Candida Peritonitis 1 item
  22. Candidemia 1 item
  23. Castration-resistant Prostate Cancer 1 item
  24. Cervical Cancer 6item
  25. Cholangiocarcinoma 2item
  26. Chronic Lymphocytic Leukemia 8item
  27. Chronic Myeloproliferative Disorders 1 item
  28. Clear Cell Renal Cell Carcinoma 2item
  29. Cocaine-Related Disorders 2item
  30. Colon Cancer 42item
  31. Colon Carcinoma 7item
  32. Colorectal Cancer 40item
  33. Depression 2item
  34. Diabetes 7item
  35. Diffuse Large B-cell Lymphoma 1 item
  36. Dyskinesia 1 item
  37. Dyslipidemia 2item
  38. Epilepsy 4item
  39. Erectile Dysfunction 4item
  40. Friedreich's Ataxia 2item
  41. Fungal Infection 1 item
  42. Fungi 1 item
  43. Glioblastoma 30item
  44. Glioma 17item
  45. HCV 4item
  46. Heart Failure 3item
  47. Hepatic Cancer 2item
  48. Hepatitis C 4item
  49. Hepatocellular Carcinoma 7item
  50. HIV 13item
  51. HIV Infections 9item
  52. Hypercholesterolemia 3item
  53. Immunological Diseases 1 item
  54. Inflammation 1 item
  55. Inflammatory Bowel Disease 1 item
  56. Inflammatory Diseases 15item
  57. Influenza 3item
  58. Kidney Injury Studies 2item
  59. Leukemia 25item
  60. Liver Cancer 4item
  61. Lung Cancer 40item
  62. Lung Carcinoma 4item
  63. Lymphoma 28item
  64. Mantle Cell Lymphoma 2item
  65. Medulloblastoma 1 item
  66. Melanoma 31item
  67. Mixed Lineage Leukemia 3item
  68. Multiple Myeloma 21item
  69. Myelofibrosis 2item
  70. Myeloma 6item
  71. Neuroblastoma 13item
  72. Neurocognitive Disorders 1 item
  73. Neuronal Protection 1 item
  74. Non-small Cell Lung Cancer 26item
  75. Non-small Cell Lung Carcinoma 2item
  76. Obsessive-Compulsive Disorder 1 item
  77. Osteoporosis 2item
  78. Ovarian Cancer 34item
  79. Pancreatic Cancer 48item
  80. Pancreatic Carcinoma 3item
  81. Prostate Cancer 51item
  82. Psoriasis 4item
  83. Psoriasis Vulgaris 1 item
  84. Pulmonary Arterial Hypertension 2item
  85. Pulmonary Fibrosis 2item
  86. Renal Cancer 4item
  87. Renal Cell Carcinoma 8item
  88. Rheumatoid Arthritis 14item
  89. Sarcoma 1 item
  90. Schizophrenia 8item
  91. Sleep Disorders 2item
  92. Soft Tissue Sarcoma 1 item
  93. Squamous Cell Carcinoma 2item
  94. Testicular Cancer 2item
  95. Thyroid Cancer 6item
  96. Tuberculosis 1 item
  97. Type 2 Diabetes 13item