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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Items 41-50 of 116

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  1. Apogossypolone (ApoG2)
    A4200 Apogossypolone (ApoG2)
     2 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor,nonpeptidic small molecule
      ≥24.55 mg/mL
  2. GSK1070916
    A4127 GSK1070916
    Target: Aurora Kinases
    Summary: Aurora B/C inhibitor
      ≥25.4 mg/mL
  3. Rigosertib
    B1288 Rigosertib
    Target: PI3K|PLK
    Summary: PI3K/PLK1 inhibitor
      Soluble in DMSO
  4. Rocilinostat (ACY-1215)
    A4083 Rocilinostat (ACY-1215)
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: Selective HDAC6 inhibitor
      ≥21.675 mg/mL
  5. U-104
    A4358 U-104
    Target: Carbonic Anhydrases
    Summary: CAIX inhibitor
      insoluble in H2O; ≥11.5 mg/mL
  6. U0126-EtOH
    A1337 U0126-EtOH
     10 Citation
    Target: MEK
    Summary: MEK1/2 inhibitor
      ≥21.33 mg/mL
  7. Everolimus (RAD001)
    A8169 Everolimus (RAD001)
     8 Citation
    Target: mTOR
    Summary: MTOR inhibitor
      ≥47.91 mg/mL
  8. Tivozanib (AV-951)
    A2251 Tivozanib (AV-951)
    Target: VEGFR
    Summary: VEGFR inhibitor,potent and selective
      ≥22.75 mg/mL
  9. Mitoxantrone HCl
    B2114 Mitoxantrone HCl
    Target: Pim|Topoisomerases|USP|HIV Integrases
    Summary: Topoisomerase II inhibitor, anti-neoplastic drug
      insoluble in EtOH; ≥51.53 mg/mL
  10. Silvestrol
    A3818 Silvestrol
    Summary: Antineoplastic
      Soluble in DMSO

Items 41-50 of 116

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  1. Reported Experiments Animal Experiments Remove This Item
  2. Related Disease Breast Cancer Remove This Item
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Category
  1. Signaling Pathways 113item
Specificity
  1. Selective 111item
Reversibility
  1. Reversible 9item
  2. Irreversible 3item
Target
  1. Cyclin-Dependent Kinases 5item
  2. Proteasome 2item
  3. Cathepsins 1 item
  4. Histone Deacetylases (HDACs) 9item
  5. Inhibitor of apoptosis proteins (IAP) 1 item
  6. Akt 3item
  7. Bcl-2 2item
  8. PI3K 8item
  9. CXCR 3item
  10. Aurora Kinases 3item
  11. Bcl-xl 2item
  12. CSF-1R 1 item
  13. EZH2 1 item
  14. mTOR 5item
  15. Bromodomains 1 item
  16. DT-diaphorases 1 item
  17. FLT3 2item
  18. P-glycoprotein (P-gp) 1 item
  19. PLK 1 item
  20. Chk 1 item
  21. VEGFR 9item
  22. PDGFR 4item
  23. c-Kit 3item
  24. Mcl-1 2item
  25. Thymidylate Synthase 1 item
  26. p38 1 item
  27. Bcr-Abl 1 item
  28. MEK 5item
  29. PORCN 1 item
  30. FGFR 2item
  31. Pim 2item
  32. Smoothened 1 item
  33. MET 1 item
  34. Src 1 item
  35. Trk Receptors 1 item
  36. STAT 2item
  37. Microtubules/Tubulins 1 item
  38. EGFR 8item
  39. FAK 1 item
  40. BMP and Other Activin Receptors 1 item
  41. JAK 2item
  42. Syk 1 item
  43. HSP90 5item
  44. Topoisomerases 2item
  45. Cytochrome P450 (CYP450) 3item
  46. Ksp 1 item
  47. ErbB 1 item
  48. Survivin 1 item
  49. c-MET 1 item
  50. PKC 2item
  51. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  52. HER2 2item
  53. USP 1 item
  54. PARP 1 item
  55. ALK 1 item
  56. ROS1 1 item
  57. D1 and D5 Receptors 1 item
  58. D2 Receptors 1 item
  59. D3 Receptors 1 item
  60. MELK 1 item
  61. CSF1R 1 item
  62. Autophagy 1 item
  63. COX 1 item
  64. CK2 1 item
  65. HIPK2 1 item
  66. HIPK3 1 item
  67. HIV Integrases 1 item
  68. PRAK 1 item
  69. MAPKAP-K2 1 item
  70. Guanine nucleotide exchange factors (GEFs) 1 item
  71. 20S proteasomal chymotrypsin 1 item
  72. Geranylgeranyltransferase I 1 item
  73. Farnesyltransferase 1 item
  74. Carbonic Anhydrases 1 item
  75. FoxM1 1 item
  76. Histone Demethylases 1 item
  77. Insulin Receptors 1 item
  78. IRG-1R 1 item
  79. eEF-2 1 item
  80. D4 Receptors 1 item
  81. DPP-4 1 item
  82. Aromatases 2item