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Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

A8395 CHIR-98014

Target: GSK-3

Summary: GSK-3β inhibitor,selective and ATP-competitive

insoluble in H2O; insoluble in EtOH; ≥8.1 mg/mL
A4489 TC-A 2317 hydrochloride

Target: Aurora Kinases

Summary: Aurora kinase A inhibitor,potent and selective

<39.29 mg/mL
B1642 WYE-125132 (WYE-132)

Target: mTOR

Summary: ATP-competitive mTOR inhibitor, highly potent

insoluble in EtOH; insoluble in H2O; ≥13 mg/mL
B1641 WAY-600

Target: mTOR

Summary: MTOR inhibitor

≥12.38 mg/mL
A1404 Rigosertib sodium salt

1 Citation

Target: PLK

Summary: Plk1 inhibitor

≥23.65 mg/mL
B3021 Atglistatin

Target: ATGL

Summary: ATGL inhibitor, potent and selective

insoluble in H2O; insoluble in EtOH; ≥14.15 mg/mL
B1309 GNE-617 hydrochloride

Target: Nampt

Summary: NAMPT inhibitor, potent and competitive

Soluble in DMSO
A8173 Romidepsin (FK228, depsipeptide)

7 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC1/HDAC2 inhibitor, potent and selective

≥27.04 mg/mL
A3126 5-R-Rivaroxaban

Target: Factor Xa

Summary: Factor Xa (FXa) inhibitor

≥20.85 mg/mL
A3185 AR-C155858

Target: Monocarboxylate transporters (MCTs)

Summary: MCT1 and MCT2 inhibitor

insoluble in H2O; ≥52.5 mg/mL