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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Items 51-60 of 116

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  1. YM155
    A4221 YM155
     2 Citation
    Target: Survivin
    Summary: Survivin suppressant,apoptosis inhibitor
      ≥22.15 mg/mL
  2. XL147
    A5112 XL147
    Target: PI3K
    Summary: PI3K inhibitor,selective and reversible
      ≥22.45 mg/mL
  3. GSK1059615
    B2176 GSK1059615
    Target: PI3K|mTOR
    Summary: PI3K and mTOR inhibitor,potent and reversible
      insoluble in EtOH; insoluble in H2O; ≥8.33 mg/mL
  4. Reparixin L-lysine salt
    A3753 Reparixin L-lysine salt
     1 Citation
    Target: CXCR
    Summary: CXCR1/CXCR2 inhibitor
      insoluble in DMSO; ≥16.67 mg/mL
  5. LY2228820
    A5566 LY2228820
     1 Citation
    Target: p38
    Summary: P38 MAP kinase inhibitor
      ≥30.65 mg/mL
  6. AC480 (BMS-599626)
    A2822 AC480 (BMS-599626)
    Target: EGFR
    Summary: HER1/2 inhibitor,selective and efficacious
      ≥28.35 mg/mL
  7. PD 0332991 (Palbociclib) HCl
    A8316 PD 0332991 (Palbociclib) HCl
     5 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor,highly selective
      ≥14.48 mg/mL
  8. Axitinib (AG 013736)
    A8370 Axitinib (AG 013736)
     1 Citation
    Target: VEGFR|PDGFR|c-Kit
    Summary: VEGFR1/ c-Kit inhibitor
      insoluble in H2O; ≥19.3 mg/mL
  9. Wnt-C59
    A8685 Wnt-C59
     2 Citation
    Target: PORCN
    Summary: PORCN inhibitor,highly potent and selective
      .95 mg/mL
      insoluble in H2O; ≥18
  10. BAY 61-3606
    A3227 BAY 61-3606
    Target: Syk
    Summary: Syk Inhibitor
      insoluble in H2O; insoluble in EtOH; ≥7.94 mg/mL

Items 51-60 of 116

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  1. Reported Experiments Animal Experiments Remove This Item
  2. Related Disease Breast Cancer Remove This Item
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Category
  1. Signaling Pathways 113item
Specificity
  1. Selective 111item
Reversibility
  1. Reversible 9item
  2. Irreversible 3item
Target
  1. Cyclin-Dependent Kinases 5item
  2. Proteasome 2item
  3. Cathepsins 1 item
  4. Histone Deacetylases (HDACs) 9item
  5. Inhibitor of apoptosis proteins (IAP) 1 item
  6. Akt 3item
  7. Bcl-2 2item
  8. PI3K 8item
  9. CXCR 3item
  10. Aurora Kinases 3item
  11. Bcl-xl 2item
  12. CSF-1R 1 item
  13. EZH2 1 item
  14. mTOR 5item
  15. Bromodomains 1 item
  16. DT-diaphorases 1 item
  17. FLT3 2item
  18. P-glycoprotein (P-gp) 1 item
  19. PLK 1 item
  20. Chk 1 item
  21. VEGFR 9item
  22. PDGFR 4item
  23. c-Kit 3item
  24. Mcl-1 2item
  25. Thymidylate Synthase 1 item
  26. p38 1 item
  27. Bcr-Abl 1 item
  28. MEK 5item
  29. PORCN 1 item
  30. FGFR 2item
  31. Pim 2item
  32. Smoothened 1 item
  33. MET 1 item
  34. Src 1 item
  35. Trk Receptors 1 item
  36. STAT 2item
  37. Microtubules/Tubulins 1 item
  38. EGFR 8item
  39. FAK 1 item
  40. BMP and Other Activin Receptors 1 item
  41. JAK 2item
  42. Syk 1 item
  43. HSP90 5item
  44. Topoisomerases 2item
  45. Cytochrome P450 (CYP450) 3item
  46. Ksp 1 item
  47. ErbB 1 item
  48. Survivin 1 item
  49. c-MET 1 item
  50. PKC 2item
  51. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  52. HER2 2item
  53. USP 1 item
  54. PARP 1 item
  55. ALK 1 item
  56. ROS1 1 item
  57. D1 and D5 Receptors 1 item
  58. D2 Receptors 1 item
  59. D3 Receptors 1 item
  60. MELK 1 item
  61. CSF1R 1 item
  62. Autophagy 1 item
  63. COX 1 item
  64. CK2 1 item
  65. HIPK2 1 item
  66. HIPK3 1 item
  67. HIV Integrases 1 item
  68. PRAK 1 item
  69. MAPKAP-K2 1 item
  70. Guanine nucleotide exchange factors (GEFs) 1 item
  71. 20S proteasomal chymotrypsin 1 item
  72. Geranylgeranyltransferase I 1 item
  73. Farnesyltransferase 1 item
  74. Carbonic Anhydrases 1 item
  75. FoxM1 1 item
  76. Histone Demethylases 1 item
  77. Insulin Receptors 1 item
  78. IRG-1R 1 item
  79. eEF-2 1 item
  80. D4 Receptors 1 item
  81. DPP-4 1 item
  82. Aromatases 2item