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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Items 71-80 of 123

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  1. LDE225 (NVP-LDE225,Erismodegib)
    B2266 LDE225 (NVP-LDE225,Erismodegib)
     1 Citation
    Target: Smoothened
    Summary: Smoothened inhibitor,potent and selective
      ≥24.3 mg/mL
  2. Motesanib
    A3632 Motesanib
    Target: VEGFR
    Summary: Inhibitor of Flk-1/Flt-4/PDGFR-/c-Kit
      ≥42 mg/mL
  3. AZD8055
    A8214 AZD8055
     2 Citation
    Target: mTOR
    Summary: MTOR inhibitor
      ≥23.3 mg/mL
  4. Dovitinib (TKI-258, CHIR-258)
    A2168 Dovitinib (TKI-258, CHIR-258)
     2 Citation
    Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Multitargeted RTK inhibitor
      insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
  5. Neratinib (HKI-272)
    A8322 Neratinib (HKI-272)
     1 Citation
    Target: EGFR
    Summary: HER2/EGFR inhibitor,potent and irreversible
      insoluble in H2O; ≥13.93 mg/mL
  6. WYE-125132 (WYE-132)
    B1642 WYE-125132 (WYE-132)
    Target: mTOR
    Summary: ATP-competitive mTOR inhibitor, highly potent
      insoluble in EtOH; insoluble in H2O; ≥13 mg/mL
  7. Gefitinib (ZD1839)
    A8219 Gefitinib (ZD1839)
     3 Citation
    Target: EGFR
    Summary: Selective EGFR inhibitor
      ≥22.34 mg/mL
  8. Indoximod (NLG-8189)
    B4900 Indoximod (NLG-8189)
    Summary: Indoleamine 2,3-dioxygenase (IDO) pathway inhibitor
      insoluble in DMSO; insoluble in EtOH; ≥1.12 mg/mL
  9. GDC-0068 (RG7440)
    A3006 GDC-0068 (RG7440)
    Target: Akt
    Summary: Pan-AKT inhibitor,highly selective
      ≥22.9 mg/mL
  10. LY2835219
    A1794 LY2835219
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor,potent and selective
      ≥30.15 mg/mL

Items 71-80 of 123

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  1. Related Disease Breast Cancer Remove This Item
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Category
  1. Signaling Pathways 120item
Specificity
  1. Selective 118item
Reversibility
  1. Reversible 9item
  2. Irreversible 3item
Target
  1. Cyclin-Dependent Kinases 6item
  2. Proteasome 2item
  3. Cathepsins 1 item
  4. Histone Deacetylases (HDACs) 10item
  5. Inhibitor of apoptosis proteins (IAP) 1 item
  6. Akt 3item
  7. Bcl-2 2item
  8. PI3K 8item
  9. CXCR 3item
  10. Aurora Kinases 4item
  11. Bcl-xl 2item
  12. CSF-1R 1 item
  13. EZH2 2item
  14. mTOR 5item
  15. Bromodomains 1 item
  16. DT-diaphorases 1 item
  17. FLT3 2item
  18. P-glycoprotein (P-gp) 1 item
  19. PLK 1 item
  20. Chk 1 item
  21. VEGFR 9item
  22. PDGFR 4item
  23. c-Kit 3item
  24. Mcl-1 2item
  25. Thymidylate Synthase 1 item
  26. p38 1 item
  27. 3-phosphoglycerate dehydrogenase 1 item
  28. Bcr-Abl 1 item
  29. MEK 5item
  30. PORCN 1 item
  31. FGFR 2item
  32. Pim 2item
  33. Smoothened 1 item
  34. MET 1 item
  35. Src 1 item
  36. Trk Receptors 1 item
  37. STAT 2item
  38. Microtubules/Tubulins 1 item
  39. EGFR 8item
  40. FAK 1 item
  41. BMP and Other Activin Receptors 1 item
  42. JAK 2item
  43. Syk 1 item
  44. HSP90 5item
  45. Topoisomerases 2item
  46. Cytochrome P450 (CYP450) 3item
  47. Ksp 1 item
  48. ErbB 1 item
  49. Survivin 1 item
  50. c-MET 1 item
  51. PKC 2item
  52. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  53. HER2 2item
  54. USP 1 item
  55. PARP 1 item
  56. ALK 1 item
  57. ROS1 1 item
  58. D1 and D5 Receptors 1 item
  59. D2 Receptors 1 item
  60. D3 Receptors 1 item
  61. MELK 1 item
  62. CSF1R 1 item
  63. Autophagy 1 item
  64. ATM/ATR 2item
  65. COX 1 item
  66. Heparanases 1 item
  67. CK2 1 item
  68. HIPK2 1 item
  69. HIPK3 1 item
  70. HIV Integrases 1 item
  71. PRAK 1 item
  72. MAPKAP-K2 1 item
  73. Guanine nucleotide exchange factors (GEFs) 1 item
  74. 20S proteasomal chymotrypsin 1 item
  75. Geranylgeranyltransferase I 1 item
  76. Farnesyltransferase 1 item
  77. Carbonic Anhydrases 1 item
  78. FoxM1 1 item
  79. Histone Demethylases 1 item
  80. Insulin Receptors 1 item
  81. IRG-1R 1 item
  82. eEF-2 1 item
  83. D4 Receptors 1 item
  84. DPP-4 1 item
  85. Aromatases 2item
Reported Experiments
  1. Animal Experiments 116item
  2. Cell Experiments 73item