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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

Search results for: 'p53 and mdm2 proteins interaction inhibitor chiral'

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  1. RG7112
    A3762 RG7112
     5 Citation
    Target: MDM2
    Summary: MDM2 inhibitor, first clinical
      ≥36.4 mg/mL
  2. AMG232
    A8804 AMG232
     2 Citation
    Target: p53-MDM2 interaction
    Summary: p53-MDM2 inhibitor, novel
      Soluble in DMSO
  3. GSK126
    A3446 GSK126
     5 Citation
    Target: EZH2
    Summary: EZH2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥4.38 mg/mL
  4. PF-04929113 (SNX-5422)
    A4065 PF-04929113 (SNX-5422)
    Target: HSP90
    Summary: Hsp90 inhibitor,potent and selective
      ≥23.85 mg/mL
  5. Tariquidar
    A8208 Tariquidar
     2 Citation
    Target: P-glycoprotein (P-gp)
    Summary: P-glycoprotein inhibitor,potent and non-competitive
      insoluble in H2O; insoluble in EtOH; ≥16.17 mg/mL
  6. MC1568
    A4094 MC1568
     3 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: Class II HDAC inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥15.7 mg/mL
  7. Valproic acid sodium salt (Sodium valproate)
    A4099 Valproic acid sodium salt (Sodium valproate)
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor
      ≥8.35 mg/mL
  8. 4E1RCat
    B3697 4E1RCat
    Target: eIF4F
    Summary: Dual inhibitor of eIF4E:eIF4G and eIF4E:4E-BP1 interaction
      ≥23.85 mg/mL
  9. Fostriecin sodium salt
    A4536 Fostriecin sodium salt
    Target: PP1|PP2A|Topoisomerases|PP4
    Summary: Antitumor antibiotic
      Soluble in H2O
  10. GDC-0941
    A8210 GDC-0941
     10 Citation
    Target: PI3K
    Summary: PI3K inhibitor,potent and selective
      ≥25.7 mg/mL

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  1. Signaling Pathways 235item
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Reversibility
  1. Reversible 9item
  2. Irreversible 9item
Target
  1. Caspases 2item
  2. Cyclin-Dependent Kinases 11item
  3. Proteasome 5item
  4. Cathepsins 2item
  5. Histone Deacetylases (HDACs) 12item
  6. Akt 3item
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  11. Aurora Kinases 7item
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  30. VEGFR 12item
  31. PDGFR 8item
  32. c-Kit 2item
  33. RET 1 item
  34. Bromodomain-containing proteins(BRDs) 1 item
  35. Phosphodiesterases (PDEs) 2item
  36. Mcl-1 2item
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  38. p38 2item
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  42. DOT1L 1 item
  43. FGFR 2item
  44. Pim 3item
  45. Deubiquitinating enzymes (DUBs) 1 item
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  58. EZH1 1 item
  59. DNA-PK 2item
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  66. HMG-CoA Reductases 1 item
  67. c-MET 5item
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  69. Calpains 2item
  70. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  71. Pyk2 2item
  72. USP 1 item
  73. 5-HT2 Receptors 1 item
  74. Insulin and Insulin-like Receptors 1 item
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  76. D1 and D5 Receptors 1 item
  77. D2 Receptors 1 item
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  79. MK2 1 item
  80. Angiotensin-Converting Enzymes (ACEs) 1 item
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  89. HIV Integrases 1 item
  90. PRAK 1 item
  91. MAPKAP-K2 1 item
  92. Guanine nucleotide exchange factors (GEFs) 1 item
  93. 20S proteasomal chymotrypsin 1 item
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  95. Farnesyltransferase 1 item
  96. Nampt 2item
  97. eIF4F 1 item
  98. Cdc42 1 item
  99. Glutaminases 1 item
  100. Carbonic Anhydrases 1 item
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  107. Inositol-requiring enzyme 1 (IRE1) 1 item
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  117. eEF-2 1 item
  118. Cdc7 1 item
  119. CMV 1 item
  120. ZAP-70 1 item
  121. Catechol O-Methyltransferase (COMT) 1 item
  122. fibrinolysis 1 item
  123. D4 Receptors 1 item
  124. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  125. Flk-1 1 item
  126. Papains 1 item
  127. Protein Arginine Methyltransferases 1 item
  128. NAE 2item
  129. Ubiquitin-activating Enzyme E1 1 item
  130. SUMOylation 1 item
  131. Cytidine deaminases 1 item
  132. angiogenesis 1 item
  133. DPP-4 1 item
  134. PP4 1 item
  135. TAM kinase 1 item
  136. p53-MDM2 interaction 1 item
  137. nuclear export 1 item
  138. CRM1 1 item
  139. AXL 1 item
  140. human lyase 1 item
  141. Ub-conjugating enzyme (E2) complex 1 item
  142. MCL1 1 item
  143. Bcl-w 1 item
  144. tropomyosin receptor kinase 1 item
  145. LSD 1 item
  146. SK 1 item
  147. IDO 1 item
  148. Substance P/NK1 Receptor 1 item